Notes on sewall wright: genetic drift
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Continuing my series of notes on the work of Sewall Wright, this one deals with the subject of genetic drift. I had originally planned to call this note 'Inbreeding and the decline of genetic variance', but anyone interested in the matters covered here, and searching for them on the internet, is far more likely to search for 'genetic drift'. This is one of the subjects most closely associated with Wright, to the extent that genetic drift was formerly often known as the 'Sewall Wright Effect'. My main aim is to help people follow Wright's own derivation of his key results, and to clarify the relationship between genetic dri...
Source: Gene Expression - May 8, 2008 Category: Geneticists and Genetics Commentators Source Type: blogs
Platypus genome
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Neil has a great summary of the results from the Platypus genome sequencing project.
© Jason Stajich for Fungal Genomes and Comparative Genomics, 2008. |
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Source: Fungal Genomes and Comparative Genomics - May 8, 2008 Category: Geneticists and Genetics Commentators Authors: Jason Stajich Tags: genome genome sequencing platypus Source Type: blogs
Genetic ethics - testing and storing our kids’ dna
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Scientists and policy developers at the Translating ELSI, Ethical Legal Social Implications of Human Genetics Research conference have been mulling over the myriad of ethical arguments over testing and storing our kids’ DNA.
The biggest driver for the advancement of genetic testing is the ‘early detection improves outcomes’ argument and if an individual is found to be at risk of a particular disease then life-long surveillance is a remedy.
However, consider the scenario that you’ve just discovered that your 9 year old daughter has a risk of developing breast and ovarian cancer and your 6 yea...
Source: Genetics and Health - May 7, 2008 Category: Geneticists and Genetics Commentators Authors: Elaine Tags: General Genetics and Health Genetic Ethics Genetic information and education bioethics Genetics and the Law Source Type: blogs
Genetic testing ethics - consent forms becoming incomprehensible
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Following my recent article on ethical guidelines for informed consent in genomic studies, a group of scientists met at the Translating ESLI conference in Cleveland to debate this whole ethical argument. This issue is particularly critical for genome-wide association studies and in establishing and using large biobanks.
It was universally acknowledged that consent forms are difficult to read for participants who do not have reading skills beyond middle school or high school, for example. As a result, these paticipants may be unaware of what exactly the research could mean to them.
Laura Beskow, a researcher at Duke Univ...
Source: Genetics and Health - May 7, 2008 Category: Geneticists and Genetics Commentators Authors: Elaine Tags: General Genetics and Health Genetic Ethics Genetic information and education Genetics and the Law bioethics consent consent forms informed consent Source Type: blogs
Cfs and me, chronic fatigue syndrome - genetic origin not only psychological
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(Image source: www.livingwithcfs.wordpress.com)
Researchers from St George’s Hospital, University of London have identified a biological basis for 7 different genetic types of Chronic Fatigue Syndrome (CFS).
The St George’s study looked at 55 patients from the US and UK with the condition, and carried out a genetic analysis of them and 75 healthy blood donors.
It identified the seven distinct subtypes of CFS/ME identified by a specific genetic pattern. These were linked to specific symptoms.
1. Type one had the worst anxiety and depression levels, along with poor sleep and high pain levels,
2. Type two w...
Source: Genetics and Health - May 7, 2008 Category: Geneticists and Genetics Commentators Authors: Elaine Tags: General Genetics and Health Genes Genetic Testing Genetics of Disease Mental health CFS Chronic fatigue syndrome Source Type: blogs
Personalized genetics: privacy and the virtual gene
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Here is the regular post about the recent improvements of individualized medicine. This week, T. Ryan Gregory at Genomicron attempted to define the term genome. While The New York Times tried to redefine disease, genes and all.
Daniel MacArthur at Genetic Future reported the low technical error rates for personal genomics companies: Of the 560,299 sites analysed by both companies (23andMe and DecodeMe), just 23 showed a different result between the two scans! Funny number, isn’t it?
Another privacy threat: personal genome projects (Kyose Blog):
What if a unauthorized person get access to the 23andme database? He ...
Source: ScienceRoll - May 7, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Genome Health Medicine Personal Health Record Personalized medicine Video genetics Source Type: blogs
Our enemy, the state
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Last fall I argued that the relatively light death toll of hurricane Sidr was due to improvements in the institutional framework of the Bangladeshi polity. More recently, I suggested that Burma's social & economic deficits vis-a-vis Bangladesh were due to negative government action. Now Chris Mooney has an article up on the reverberations of hurricane Nargis. Here's what caught my attention: Read the rest of this post... | Read the comments on this post... (Source: Gene Expression)
Source: Gene Expression - May 7, 2008 Category: Geneticists and Genetics Commentators Tags: Politics Source Type: blogs
Medicine 2.0 carnival at canadian medicine
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The 23rd edition is up at the Canadian Medicine! Check out the many posts and news about the world of medicine 2.0 and health 2.0. I’m thankful to the whole Canadian Medicine Team, and especially Sam Solomon, for hosting Medicine 2.0!
Medicine 2.0 editions so far:
Edition #1: Scienceroll
Edition #2: Scienceroll
Edition #3: Medical 2.0
Edition #4: Healthline Connects
Edition #5: The Health Wisdom Blog
Edition #6: Sharp Brains
Edition #7: DavidRothman.net
Edition #8: Constructive Medicine
Edition #9: Clinical Cases and Images
Edition #10: Highlight HEALTH
Edition #11: The Health Wisdom Blog
Edition#12: Medical 2.0
Editio...
Source: ScienceRoll - May 7, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Blog Carnival Medicine Medicine 2.0 Source Type: blogs
Pleiotropy in melanocortin receptors
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In the comments here, rosko points me to a study on the effects on MC4R, a gene implicated in natural variation in human weight, on pathways involved in sexual function. It's well known, of course, that genetic pathways can be involved in multiple physiological processes--in particular, signaling pathway can generate many different phenotypes depending on what the downstream target of the signal is. The effects of MC4R simulation in humans are, as rosko comments, kind of interesting:Methods. Ten subjects were enrolled in a double-blind, placebo-controlled, crossover study. Melanotan II (0.025 mg/kg) and vehicle were each a...
Source: Gene Expression - May 7, 2008 Category: Geneticists and Genetics Commentators Tags: Genetics Source Type: blogs
Get off your ass and start this project: viral videos
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Having already motivated this series, I'll provide the first example of how to put your time to more productive use than participating in the WikiProject G.I. Joe or the still more urgent WikiProject Transformers. If you get interesting results, post them on your blog and provide a link in the comments here. I'll gather up all the results after awhile and summarize them in a follow-up post.PurposeCultural transmission has often been described verbally as viral. Mathematical models of culture incorporate this idea by borrowing epidemic disease models from biology. The goal here is to see if data on "viral videos" support th...
Source: Gene Expression - May 6, 2008 Category: Geneticists and Genetics Commentators Tags: do it yourself studies Source Type: blogs
Deep est sequencing = rna-seq
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The transcriptional landscape of yeast has been (further) defined with Solexa sequencing in a method deemed "RNA-Seq", but what I would call "deep EST sequencing". This approach for transcriptional profiling by sequencing alone is sure to be used by many labs looking for lower and more complete ways to describe and quantitate the full population of transcripts in an organism.
Nagalakshmi, U., Wang, Z., Waern, K., Shou, C., Raha, D., Gerstein, M., Snyder, M. (2008). The Transcriptional Landscape of the Yeast Genome Defined by RNA Sequencing. Science DOI: 10.1126/science.1158441
© Jason Stajich for Funga...
Source: Fungal Genomes and Comparative Genomics - May 6, 2008 Category: Geneticists and Genetics Commentators Authors: Jason Stajich Tags: genome sequencing saccharomyces yeast solexa transcripts Source Type: blogs
Involvement of bardet-biedl proteins in neural crest cell migration
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Proc Natl Acad Sci U S A. 2008 Apr 28 [Epub ahead of print]
Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung’s disease in Bardet-Biedl syndrome.
Tobin JL, Di Franco M, Eichers E, May-Simera H, Garcia M, Yan J, Quinlan R, Justice MJ, Hennekam RC, Briscoe J, Tada M, Mayor R, Burns AJ, Lupski JR, Hammond P, Beales PL.
In this publication, the authors combine data from facial dysmorphology modeling, with experiments in mice and zebrafish to demonstrate their hypothesis that the proteins mutated in Bardet-Biedl syndrome are involved in neural crest cell migration.
Thank you very ...
Source: The OMMBID Blog - May 6, 2008 Category: Geneticists and Genetics Commentators Authors: pcampeau Tags: Part 30: MULTISYSTEM INBORN ERRORS OF DEVELOPMENT Source Type: blogs
Lancet and the sherpa
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After reading an editorial from the Lancet...I think that they may be reading the Sherpa. Let me know what you think. From the Lancet "Genome Wide Open"Interpretations of the effects of human genotypes on disease are today just entering the foothills of a forbidding massif. In particular, a much richer understanding of human genetic variation is needed. However, the relentless ascent of human genomics is coinciding with growing public interest in maintaining health and participating in health-care choices. Doctors will face challenges in guiding their patients through genetic terrain strewn with difficult language and conc...
Source: Gene Sherpas: Personalized Medicine and You - May 6, 2008 Category: Geneticists and Genetics Commentators Tags: Lancet helix health drudge report DNA direct 23 and me navigenics Source Type: blogs
Osteoporosis and gene tests
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Osteoporosis, or porous bone, is a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures, especially of the hip, spine and wrist, although any bone can be affected.In simpler terms, osteoporosis is a condition in which the bones become weak and can break from a minor fall or, in serious cases, from a simple action such as a sneeze.About 85-90% of adult bone mass is acquired by age 18 in girls and 20 in boys. Building strong bones during childhood and adolescence can help to preventosteoporosis later in life.In the U.S. toda...
Source: Gene Sherpas: Personalized Medicine and You - May 6, 2008 Category: Geneticists and Genetics Commentators Tags: helix health deCode hillary clinton DNA direct barack obama 23 and me osteoporosis navigenics john mccain Source Type: blogs
Weight gain, diabetes, expanding waist line and a gene sequence
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Scientists from Imperial College London and other international institutions have discovered a gene sequence that is associated with a 2cm expansion in waist circumference, a 2kg gain in weight, and a tendency to become resistant to insulin, which can lead to type 2 diabetes. The sequence is found in 50% of the UK population.
The study shows that the sequence is a third more common in those with Indian Asian than in those with European ancestry. This could provide a possible genetic explanation for the particularly high levels of obesity and insulin resistance in Indian Asians, who make up 25% of the world’s po...
Source: Genetics and Health - May 5, 2008 Category: Geneticists and Genetics Commentators Authors: Elaine Tags: DNA sequencing Diabetes General Genetics and Health Genetics of Disease obesity weight gain Source Type: blogs
Get off your ass and do this study: introductory pep talk
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I was recently directed to this panegyric on Wikipedia, which claims that editing Wikipedia is a better use of the cognitive surplus that might otherwise be spent watching TV. Like 99% of technology pundits, the author is so out of touch with reality that it is not worth taking him to task in depth. Instead, reading that has moved me to begin a regular column wherein I propose a fairly simple study for someone to carry out and increase our understanding of the world.In fairness, it is often tough to think of a study to do, or how you would concretely carry it out. But since my soul is a font of generosity, I'm literally gi...
Source: Gene Expression - May 5, 2008 Category: Geneticists and Genetics Commentators Tags: do it yourself studies Source Type: blogs
Jim manzi on expelled
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Show Me the Science. Read the comments on this post... (Source: Gene Expression)
Source: Gene Expression - May 5, 2008 Category: Geneticists and Genetics Commentators Tags: Creationism Source Type: blogs
Squirrel fun
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For many years, Grey Squirrels (an introduced North American species) has been driving out the indigenous Red Squirrel over most of mainland Britain. But now it is reported that a mutant black variety of the Grey Squirrel is threatening to displace the Greys. Apparently, the black ones have higher testosterone levels, are more aggressive, and more attractive to the lady squirrels. (Don't worry, our White Nationalist readers, this isn't a parable. I think.) Joking apart, the real interest of this is that it seems to be a case of a single mutation with a relatively conspicuous phenotypic effect having a strong evolutionary a...
Source: Gene Expression - May 5, 2008 Category: Geneticists and Genetics Commentators Source Type: blogs
Nextbio: life sciences data search engine
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Almost a year ago, I wrote NextBio was just like using Pubmed but in a more dynamic way. Now the public version was launched so it’s free for everyone.
With NextBio, in just one click users can search through thousands of studies with billions of data points spanning across different experimental platforms, organisms and data types. It also searches across millions of publications to help find new articles pertaining to your search query. NextBio’s data and literature search engine makes massive amounts of disparate biological, clinical and chemical data from public and proprietary sources searchable, regard...
Source: ScienceRoll - May 5, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Bioinformatics Medical Search e-Science Source Type: blogs
4 in 1: video, podcast, photo and pubmed
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There are nearly 25 sites and services focusing on medical videos and animations on my list I’ve been working on for months. Here is the newest addition, The DAVE Project - Gastroenterology:
The DAVE Project, an acronym for the Digital Atlas of Video Education, is a collection of teaching tools. The project consists of a gastrointestinal endoscopy video atlas and medical lectures and presentations. The most recent additions to the collection are displayed below. Physicians are encouraged to submit material, for consideration, new entries to enrich and expand the atlas.
We can watch the videos or download them;...
Source: ScienceRoll - May 5, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Health Medical Imaging Medical education Medicine Medicine 2.0 Video Web 2.0 Source Type: blogs
Weight and genetics
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Two studies report this week on the association of variation near MC4R with body mass. This is the second convincingly replicated locus to be implicated in natural variation in weight, the first being FTO. There are a couple reasons I find this association interesting. 1. Coding mutations in MC4R are known to cause severe obesity. It's to be expected that less severe mutations (the region of the genome implicated in these studies is likely regulatory) could lead to more subtle effects on body weight, but it didn't have to be that way. And this forms part of a pattern that genes that cause Mendelian forms of a disease are a...
Source: Gene Expression - May 4, 2008 Category: Geneticists and Genetics Commentators Tags: Genetics Source Type: blogs
Dichotomous inverts
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Kevin has posted the newest Circus of the Spineless at Deep See Nudes News. Go get your monthly fix of inverts. Read the comments on this post... (Source: evolgen)
Source: evolgen - May 4, 2008 Category: Geneticists and Genetics Commentators Tags: Blog Carnivals Source Type: blogs
Strange bedfellows
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For general amusement, see this report from the BBC. (Via John Hawks.) (Source: Gene Expression)
Source: Gene Expression - May 4, 2008 Category: Geneticists and Genetics Commentators Source Type: blogs
Genetics blogs round up - gene genie#30
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(Image courtesy of Ricardo Vidal at My Biotech Life)
Many thanks to Razib at Gene Expression for hosting Gene Genie#30, the carnival of genetics blogs. Click on the following link to get a great summary on all that is happening in the genetics blog word. There are some great articles, including some from G&H.
http://scienceblogs.com/gnxp/2008/04/gene_genie_30.php
Here are links to all the previous Gene Genie Carnivals.
Issue #1: Scienceroll
Issue #2: Sciencesque
Issue #3: Genetics and Health
Issue #4: Sandwalk
Issue #5: Neurophilosophy
Issue #6: Scienceroll
Issue #7: Gene Sherpa
Issue #8: Eye on DNA
Issue #9: DN...
Source: Genetics and Health - May 4, 2008 Category: Geneticists and Genetics Commentators Authors: Elaine Tags: Featured Genetics and Health Blogs General Genetics and Health Genetics Blogging Genetics and Health Blog Carnivals gene-genie genetics carnivals Source Type: blogs
Meet gna - dna’s ‘ambidextrous’ cousin
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GNA
(Source: John Chaput, University of Arizona)
Nanotechnology researchers are continually on the lookout for new building blocks to push innovation and discovery to scales much smaller than the tiniest speck of dust. At present DNA nanotechnology researchers are basically limited by what they can buy off the shelf.
In the Biodesign Institute at Arizona State University, researchers led by John Chaput, are building synthetic molecules that assemble like DNA, but have additional properties not found in natural DNA. It’s called GNA. In the case of GNA, the sugar is the only difference with DNA. The five carbon ...
Source: Genetics and Health - May 4, 2008 Category: Geneticists and Genetics Commentators Authors: Elaine Tags: DNA General Genetics and Health nanotechnology GNA Source Type: blogs
Osteoporosis - finding the genetic fingerprint
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Osteoporosis
(Image source: www.soylabs.com)
An extensive genome-wide search has been undertaken to find the genes linked to osteoporosis and fracture. Five regions of interest have been identified that appear to warrant further scientific investigation.
The Garvan Institute for Medical Research collaborated with the Icelandic genetics company, deCode, in a project that looked at 1500 women from Garvan’s Dubbo Osteoporosis Epidemiology Study as well as more than 12,000 women from Iceland and Denmark.
The collaborative study examined more than 300,000 such markers and found 12 that were linked to bone mineral ...
Source: Genetics and Health - May 4, 2008 Category: Geneticists and Genetics Commentators Authors: Elaine Tags: DNA DNA profiling General Genetics and Health Genes Genetic Testing Genetics of Disease deCode geneticn testing osteoporosis SNPs Source Type: blogs
Female hair loss - new genetic test available
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(Photo source: www.female-alopecia.com)
Until now, Female Hair Loss has been difficult to predict and diagnose. That changes with today’s announcement that HairDX, LLC pioneers of consumer-friendly genetic tests for hair loss, has introduced a screening test using genetic markers strongly associated with Female Hair Loss (Female Androgenetic Alopecia).
The easy to understand test, which costs US$149, provides an accurate and understandable genetic analysis of a woman’s likelihood of developing this common type of hair loss.
“Helping women assess their risk for Female Hair Loss early in the course of th...
Source: Genetics and Health - May 4, 2008 Category: Geneticists and Genetics Commentators Authors: Elaine Tags: General Genetics and Health Genetic Testing baldness female female hair loss Source Type: blogs
Human genome - first map of cultural variations
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A nationwide team of researchers, funded in part by the National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), has produced the first sequence-based map of large-scale structural variation across the human genome.
Recently created maps such as the HapMap have catalogued the patterns of small-scale variations in the genome that involve single DNA letters, or bases. A sequence-based map provides much finer resolution and location information.
Researchers constructed the structural variation map by partially sequencing the genomes of eight people: four people of African descent, tw...
Source: Genetics and Health - May 4, 2008 Category: Geneticists and Genetics Commentators Authors: Elaine Tags: Ancestry DNA sequencing Genealogy and DNA General Genetics and Health Genome sequencing Human Genome geneaology genme sequencing HapMap sequence map Source Type: blogs
Leukemia - risk of which patients could relapse, identified
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(Photo courtesy www.leukemia101.com)
Researchers at the Ohio State University Comprehensive Cancer Center may have discovered a better way to distinguish acute leukemia patients who require aggressive treatment to prevent recurrence from those who need only standard therapy for cure.
About 13,300 new cases of AML and 8,200 deaths from the disease are expected this year in the United States.
In about half of cases, patients’ leukemia cells have chromosome changes that help doctors determine whether standard therapy will suffice to prevent recurrence, or whether the individual needs aggressive treatment such as a ste...
Source: Genetics and Health - May 4, 2008 Category: Geneticists and Genetics Commentators Authors: Elaine Tags: Chromosome abnormalities General Genetics and Health Genetics of Disease Leukemia Personalized Medicine RNA chromosomes acute myeloid leukemia cancer Genetic Testing microRNA relapse Source Type: blogs
Internal medicine journal search: personalize your searches!
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Have you ever heard about Google Co-op? According to Wikipedia:
Google Co-op is a platform provided by Google that allows web developers to feature specialized information in web searches, refine and categorise queries and create customized search engines, based on Google Web Search.
Flavio Guzmán created his own search engine, the Internal Medicine Journal Search where we can search on the top 5 medical journals: JAMA, NEJM, BMJ, AIM and Lancet.
This is a great example on how to create a customized search engine. Another example is the Scienceroll Personalized Search Engine where you can choose which databases to search...
Source: ScienceRoll - May 3, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Medical Search Medical journalism Medicine Medicine 2.0 Source Type: blogs
Gene2mesh: automated literature based genome annotation
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Some weeks ago, I mentioned on Twitter how hard it is to find proper gene-disease associations in Pubmed, the database of health-science data. Some days later, P. F. Anderson sent me this link: Gene2MeSH.
According to her:
Gene2MeSH was described 2 me as mapping various terms used 2 describe the same gene, or genes assoc w/ medical term
I gave it a try and made a search for psoriasis:
It looks like an interesting and useful idea, while the MeSH heading column seems to be totally unnecessary, for example.
I will keep on using it and will let you know how it goes.
Further reading:
NCBI Introduction to Molecular Biology In...
Source: ScienceRoll - May 3, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Bioinformatics Gene Invention Medicine genetics Source Type: blogs
What’s on the web (2008 may 3)
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Video: “I Wanna Be a DNR” Sung to Rockstar by Nickelback (Clinical Cases and Images):
What does DNA mean to you? #3 (Eye on DNA): It was my turn. Thank you, Hsien, for the opportunity!
QuizMD - practice exam questions (Medical Education Blog): I must try it now.
X-Games Athletes have Modified Anatomy (Street Anatomy):
New TED Talk: Ernest Madu talks about Bringing world-class health care to the poorest (Source: ScienceRoll)
Source: ScienceRoll - May 3, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Video What's on the web? Source Type: blogs
2 women, one prize, oprah and a new industry
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The Albany Medical Center Prize in Medicine and Biomedical Research was recently awarded to 2 scientists for their work on snRNPs and Telomerase. Oh yes, that magical molecule that will allow us to live as long as Methusaleh, or some would claim. What is telomerase?The "clock" of cellular life was once a mystery to scientists. But soon they found that telomeres, the tips of chromosomes. Or as Dr Oz loves to say, the wrapping at the end of the shoelace, becomes progressively shorter over the life of a cell and when they become too short, cells die.Dr. Blackburn one of the 2 scientists showed that telomerase can add DNA back...
Source: Gene Sherpas: Personalized Medicine and You - May 3, 2008 Category: Geneticists and Genetics Commentators Tags: mehmet oz oprah winfrey ta sciences O magazine barack obama 23andme telomere youtube telomerase Source Type: blogs
Iron man
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Saw Iron Man with that genderist SOB Jake Young. All I can say is that it is nice that G. K. Paltrow finally has a hit on her hands after all these years.... Read the comments on this post... (Source: Gene Expression)
Source: Gene Expression - May 3, 2008 Category: Geneticists and Genetics Commentators Source Type: blogs
Medical bloggers’ panel: anyone interested?
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We are currently recruiting bloggers who would be interested in participating in a Medical Bloggers’ Panel during the Medicine 2.0 Congress taking place in Toronto, Canada this September, 4-5.
Some details:
Panels are 45-60 min presentations or debate sessions of a group of leaders in a field discussing a broad issue of general interest from various perspectives.
Please note that normally we will not be able to cover the registration fee, travel and accommodation for any of the panelists.
The abstract should contain up to 500 words, containing a short overview of the common issues and 1-2 sentences per presenter abo...
Source: ScienceRoll - May 2, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Blogging Conference Medicine 2.0 Source Type: blogs
I am still alive
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It may seem to all of you that I have disappeared. I am still here. I think about you all everyday. Unfortunately, things in my life have been super crazy lately causing me to have to quit my job.The good news is, after my last day at the end of this month, I will be back in full blogging mode! I hope to see you then! (Source: Mary Meets Dolly)
Source: Mary Meets Dolly - May 2, 2008 Category: Geneticists and Genetics Commentators Source Type: blogs
Katz
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Read the rest of this post... | Read the comments on this post... (Source: Gene Expression)
Source: Gene Expression - May 2, 2008 Category: Geneticists and Genetics Commentators Tags: Blog Source Type: blogs
Dioxin cleanup with fungi
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NYT article on the work of Paul Stamets using fungi like Pleurotus for Dioxin cleanup in Ft Bragg, CA.
Thanks for the link Pat!
© Jason Stajich for Fungal Genomes and Comparative Genomics, 2008. |
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Source: Fungal Genomes and Comparative Genomics - May 1, 2008 Category: Geneticists and Genetics Commentators Authors: Jason Stajich Tags: bioremediation fungi homobasidiomycota basidiomycete cleanup mushroom pleurotus Source Type: blogs
Ball's in bush's court and why i love genome technology online!
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I hope everyone who reads this will subscribe to Genome Technology Online (This is not a paid advertisement this is my opinion).Why? If you are asking this, it is likely because you have never received the email newsletter. I am always impressed by their ability to capture the essence of what is going on in the Genome World Daily. They have excellent reports for purchase as well. But frankly, just getting the email everyday makes my heart twitter (I can't get sued for using that word can I?)Today they poke fun at Corporate Genomics and make mention of 2 very well written articles. One over at the Wall Street Journal. Yeste...
Source: Gene Sherpas: Personalized Medicine and You - May 1, 2008 Category: Geneticists and Genetics Commentators Tags: deCODEme helix health Myriad hillary clinton DNA direct barack obama 23 and me BRCA navigenics Source Type: blogs
Health news in second life: virtual conference
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Second Life is a virtual world with more and more educational resources and in this series, I try to keep you up-to-date about these.
Second Life, Education: Health Science Endeavors in Second Life? Always growing! (EBM and Clinical Support Librarians@UCHC):A really comprehensive compilation of what we have now in Second Life in the medical field.
Search in Second Life Opens Up! (Health & Medicine in Second Life): The new build-in browser in SL opens up massive opportunities to search in web-based resources out there on the Web.
The site of Second Nature on Nature.com is quite impressive:
International Virtual...
Source: ScienceRoll - May 1, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Health Medicine Medicine 2.0 Second Life Web 2.0 Source Type: blogs
The mission of navigenics: interview
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Navigenics is a company focusing on personalized genetics and it launched its service just weeks ago. Dr. Dietrich Stephan, a human geneticist at Navigenics, agreed to answer some of my questions.
As a co-founder, why did you take part in constructing such a service?
My mother died of breast cancer when she was in her early 30’s due to a missed lump. This shaped my career and guided me toward developing effective early diagnostics and new knowledge-based therapies for human disease. I have been working in academia for the last 15 years to identify gene variants that cause human disease.
My group has been involved ...
Source: ScienceRoll - May 1, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Genetic testing Genome Health Medicine Navigenics Personalized medicine genetics Source Type: blogs
The new brca and subsegments of a segment
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First and Foremost,To all women who have hereditary patterns of Breast Cancer, but have a negative BRCA work up....there is new information which deCode has released in Nature Genetics. I was very excited about this and look forward to some significant replications.From a recent MarketWatch report Common variants previously discovered by deCODE on chromosomes 2q35 and 16q12 are together involved in an estimated 25% of ER+ breast cancers. The analysis in today's paper also reveals that a fourth known set of variants, located on chromosome 10q26 and accounting for approximately 16% of breast cancers, appear to confer risk ex...
Source: Gene Sherpas: Personalized Medicine and You - April 30, 2008 Category: Geneticists and Genetics Commentators Tags: deCODEme forbes helix health DNA direct 23 and me BRCA navigenics Source Type: blogs
Potential for vitamin d synthesis
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From The evolution of human skin coloration, page 12: Read the rest of this post... | Read the comments on this post... (Source: Gene Expression)
Source: Gene Expression - April 30, 2008 Category: Geneticists and Genetics Commentators Tags: Genetics Source Type: blogs
Doping & genetic background?
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Some Athletes' Genes Help Outwit Doping Test :The 55 men in a drug doping study in Sweden were normal and healthy. And all agreed, for the sake of science, to be injected with testosterone and then undergo the standard urine test to screen for doping with the hormone.The results were unambiguous: the test worked for most of the men, showing that they had taken the drug. But 17 of the men tested negative. Their urine seemed fine, with no excess testosterone even though the men clearly had taken the drug.It was, researchers say, a striking demonstration of a genetic discovery. Those 17 men can build muscles with testosterone...
Source: Gene Expression - April 30, 2008 Category: Geneticists and Genetics Commentators Tags: Genetics Source Type: blogs
Stem rust
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Spread of wheat rust Puccinia strain Ug99 and consequences on already strained food supplies is discussed in an Op-Ed piece covered in GeneticMaize.
© Jason Stajich for Fungal Genomes and Comparative Genomics, 2008. |
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Want more on these topics ? Browse the archive of posts filed under plant pathogen, rusts. (Source: Fungal Genomes and Comparative Genomics)
Source: Fungal Genomes and Comparative Genomics - April 29, 2008 Category: Geneticists and Genetics Commentators Authors: Jason Stajich Tags: plant pathogen rusts food shortage grain puccinia wheat Source Type: blogs
Anatomical theatre
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I found this on BoingBoing:
Anatomical Theatre is a photographic exhibition documenting artifacts collected by and exhibited in medical museums throughout Europe and the United States. The objects in these photos range from preserved human remains to models made from ivory, wax, and papier mâché. The artifacts span from the 16th Century to the 20th, and include examples from a wide range of countries, artists, and preparators.
Further reading:
3D Anatomy Online
The Papier-Mache Anatomist
Anatomical heart made from candy hearts
Amazing medical images at Street Anatomy (Source: ScienceRoll)
Source: ScienceRoll - April 29, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Anatomy Art science Source Type: blogs
How not to give a presentation!
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This slideshow, I found at Clinical Cases and Images, is one of the best ones I’ve ever seen. It focuses on how not to give a presentation:
I’m a medical student so I know exactly what it is like to sit and watch plenty of bad and long presentations while I still believe even the worst and most boring subjects could be visualized properly on a well-structured slideshow.
I’ve given dozens of slideshows about web 2.0 and medicine and they changed a lot after my US trip this February. I realized the aim is not to transmit all the information you have, but to persuade your audience to search for your project...
Source: ScienceRoll - April 29, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Fun Medicine 2.0 Web 2.0 presentation Source Type: blogs
What predicts creationism?
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Public Acceptance of Evolution (Source: Gene Expression)
Source: Gene Expression - April 29, 2008 Category: Geneticists and Genetics Commentators Tags: creationism Source Type: blogs
Ben stein is a barbarian?
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John Derbyshire has a long column excoriating Ben Stein and the Discovery Institute titled A Blood Libel on Our Civilization: Read the rest of this post... | Read the comments on this post... (Source: Gene Expression)
Source: Gene Expression - April 29, 2008 Category: Geneticists and Genetics Commentators Tags: Creationism Source Type: blogs
Online gene tests: anyone purchased one of these tests?
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For an upcoming series on genetic testing, a major TV network would like to interview a person who has ordered an online gene test to assess their future risk of getting certain diseases, and would like to share their experience and reaction to their test results. Twelve complaints have been filed with the California Dept of Health, and the New York State Dept of Health has sent letters explaining the legal ramifications of testing New York residents without the proper clinical laboratory permit. Most of these complaints are anonymous. Would anyone speak on-camera to their issues and share their personal experience orderin...
Source: ScienceRoll - April 29, 2008 Category: Geneticists and Genetics Commentators Authors: Bertalan Meskó Tags: Genetic testing Source Type: blogs
