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Follow The 1x Objective on Twitteremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Follow me on Twitter: https://twitter.com/1xObjective Catch the rest of the story after the break... (Source: The 1x Objective)
Source: The 1x Objective - March 11, 2010 Category: Pathologists Authors: robstak Tags: Informatics Medicine Pathology Source Type: blogs

BioImagene PR Doing It The Apple Way…email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
I brought this up last year with one of my first blog posts, and it looks like BioImagene is at it again.  It speaks nothing about their actual products/services, but I really think more companies... Catch the rest of the story after the break... (Source: The 1x Objective)
Source: The 1x Objective - March 11, 2010 Category: Pathologists Authors: robstak Tags: Uncategorized Source Type: blogs

Technology Causes Upheaval in the Air Force; Relevance for Diagnosticiansemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Although we are not always acutely aware that such changes are occurring, technology innovations can have a profound effect on various aspects of our lives such as the nature of our work or business models. One example of such an innovation is digital radiology which set the stage for Nighthawk Radiology Services and the emergence of global teleradiology networks. A recent article discussed the conundrum for U.S. Air Force generals about how to manage and reward drone pilots who have never stepped into a combat jet (see: Combat Generation: Drone operators climb on winds of change in the Air Force). Below is an excerpt from...
Source: Lab Soft News - March 11, 2010 Category: Pathologists Authors: Bruce Friedman Tags: Anatomic Pathology Digital Imaging in Pathology Healthcare Solutions Other than Lab Hospitals and Healthcare Delivery Imaging Other Than Pathology Source Type: blogs

more tweeting!email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Hi everyone - just wanted to let y'all know, we're going to start Tweeting a bit more... up 'till now we've used our Twitter feed as a way to let you know when we've posted something on the blog.  Which is great, but a lot of other stuff happens at Aperio too, and we want to let you know about all of those things.  So, please follow us on Twitter and we'll keep you posted! (Source: The Daily Scan)
Source: The Daily Scan - March 11, 2010 Category: Pathologists Authors: Ole Eichhorn Source Type: blogs

BioImagene Introduces the iSlide™ to Enhance the Transition from Manual to Digital Pathologyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
BioImagene has provided sneak peeks of this technology in the past year.  One of the last hurdles for digital pathology adoption remains the human user interface component.  While the mouse is suitable for a number of computing functions, devices or inputs that are similar to conventional glass slides and microscopy may be critical for most users.  This may provide one device that in addition to reasonable scan times and faster viewing will allow for increased use.  (Source: Digital Pathology Blog)
Source: Digital Pathology Blog - March 11, 2010 Category: Pathologists Authors: Kaps Source Type: blogs

Marijuana Use by Seniors Increases; Medical Record Implicationsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
There's no surprise in this news. People who began to use marijuana as their recreational drug of choice in the 1960's and 1970's have continued this habit as they age. This has lead to an emerging "drug problem" for seniors (see: Marijuana use by seniors goes up as boomers age). I use quotes here because I am not sure that a problem actually exists, but read on. Below is an excerpt from the article:The number of people aged 50 and older reporting marijuana use in the prior year went up from 1.9 percent to 2.9 percent from 2002 to 2008, according to surveys from the Substance Abuse and Mental Health S...
Source: Lab Soft News - March 10, 2010 Category: Pathologists Authors: Bruce Friedman Tags: Electronic Medical Record Hospitals and Healthcare Delivery Medical Consumerism Source Type: blogs

Dose of platelets in prophylactic transfusions for severe thrombocytopeniaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Slichter and colleagues published a multi-institutional randomized trial in the February 18 issue of New England Journal of Medicine (article abstract) that evaluates the effect of platelet dose on various transfusion and clinical outcomes in patients receiving prophylactic transfusions for severe hypoproliferative thrombocytopenia.The study included 1272 hospitalized patients who underwent allogeneic or autologous hematopoietic stem cell transplant (HSCT) or chemotherapy for hematologic or solid malignancies who were expected to have platelet counts of 10,000/mm3 or less for 5 or more days and received at least 1 plt tran...
Source: The Daily Sign-Out - March 10, 2010 Category: Pathologists Authors: Mark D. Pool, M.D. Tags: Blood Banking Platelet Transfusion Transfusion Medicine Source Type: blogs

Registration Is Open for Pathology Visions 2010email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
JOIN US FOR PATHOLOGY VISIONS 2010 (Source: Digital Pathology Blog)
Source: Digital Pathology Blog - March 10, 2010 Category: Pathologists Authors: Kaps Source Type: blogs

Plans for Lab Week?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
National Medical Laboratory Week is an annual celebration of the clinical laboratory’s greatest asset—the staff! This year the celebration will be held April 18-24. What plans do you have for recognizing your team’s dedication, talent, skills and devotion...(read more) (Source: ADVANCE Discourse: Lab)
Source: ADVANCE Discourse: Lab - March 9, 2010 Category: Pathologists Authors: Lynn Nace Source Type: blogs

Platelets Can Replicate in the Blood Steam Despite the Absense of Nucleiemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Among the many ideas that were drummed into my head during my early training years was that platelets could not reproduce in the blood stream. This stands to reason in that they are anucleate, having budded off from the cytoplasm of megakaryocytes in the marrow. It now turns out that this idea may not be correct (see: Understanding Of Blood Cell Development Challenged By Discovery That Platelets Can Reproduce In Circulation). Below is an excerpt from an article from the web:University of Utah researchers led an international team of scientists that is the first to report on the previously undescribed ability of platelets t...
Source: Lab Soft News - March 9, 2010 Category: Pathologists Authors: Bruce Friedman Tags: Blood Banking Clinical Lab Industry News Laboratory Industry Trends Medical Research Source Type: blogs

What is the relative prevalence of CNS metastases versus primary tumors?: Simple question, complex answeremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
During the pre-exam pathology review session at my medical school, one of the students asked about the relative incidence of metastases to the CNS versus primary CNS neoplasms. I answered that metastases are ten times more common than primary tumors. After the presentation, a colleague in the audience pointed out to me that the current issue of Robbins and Cotran (p. 1330) says: "about half to three quarters are primary tumors, and the rest are metastatic." I said, "No way!" and produced another textbook (the current edition of "Greenfield's Neuropathology"), which states the following on page 2116: "Metastatic tumors to t...
Source: neuropathology blog - March 9, 2010 Category: Pathologists Source Type: blogs

VA shuts access to DoD medical records after data errorsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Health information interoperability efforts between the Veterans Health Administration and the Military Health System suffered another setback, as the Department of Veterans Affairs cut off access to the Defense Department's AHLTA EMR after VA officials found errors in medical records downloaded from AHLTA. (Source: Digital Pathology Blog)
Source: Digital Pathology Blog - March 9, 2010 Category: Pathologists Authors: Kaps Source Type: blogs

Case of the Week 45email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
An inflamed appendix was removed surgically and sent to Surgical Pathology. When it was cut open, approximately 15 of the following objects were found inside the lumen: (Source: pathtalk.org)
Source: pathtalk.org - March 8, 2010 Category: Pathologists Authors: Bobbi Pritt Tags: Cases Microbiology Source Type: blogs

Answer to Case of the Week 44email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Well, this was definitely a challenging case this week! Many of you wrote in with suggestions that this is some type of fly larvae, and that is certainly a good thought. However, there are no structures such as spines or mouth parts to confirm this identity, and the history would be a bit odd. Instead, this is actually a proglottid of Dipylidium caninum, the double-pored dog tapeworm. Although classically likened to “grains of rice,” mature and gravid proglottids have been described as “pumpkin seed” shaped (as seen here). The diagnosis is confirmed by identifying the characteristic egg packets of...
Source: pathtalk.org - March 8, 2010 Category: Pathologists Authors: Bobbi Pritt Tags: Cases Microbiology Source Type: blogs

Case of the Week 108email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
An inflamed appendix was removed surgically and sent to Surgical Pathology. When it was cut open, approximately 15 of the following objects were found inside the lumen:(CLICK ON IMAGES TO ENLARGE) (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - March 8, 2010 Category: Pathologists Source Type: blogs

Culture of Trust in Healthcareemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Culture is yet another buzz word in healthcare, where it often seems we are “buzzed” in all directions. Sometimes, it is my head that is buzzing nonstop. An article at Compliance On-Line discusses a culture of trust in the workplace. Katherine Holmes,...(read more) (Source: Changing Face of Lab Medicine)
Source: Changing Face of Lab Medicine - March 8, 2010 Category: Pathologists Authors: Sheryl Whitlock Tags: Employee/Staffing Issues Source Type: blogs

Correlation of Sociodemographic Status with Personal Engagement in Cancer Screening Programsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Of great interest to me is the strong correlation of good health and long life with one's level of education. It's a much stronger correlation than even wealth and socio-economic status. On the face of it and in order to explain this finding, one might surmise that more educated people have a better understanding about how to preserve their health or seek therapy when sick. There is also an interesting parallel theory that educated people have invested time and money over many years in themselves, postponing their high-earning years to later in life. A conclusion, based on this scenario, is that their concern for b...
Source: Lab Soft News - March 8, 2010 Category: Pathologists Authors: Bruce Friedman Tags: Clinical Lab Industry News Clinical Lab Testing Hospitals and Healthcare Delivery Laboratory Industry Trends Medical Consumerism Public Health Informatics Source Type: blogs

www.tissuestudio.com Now Liveemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Digital Pathology Blog)
Source: Digital Pathology Blog - March 7, 2010 Category: Pathologists Authors: Kaps Source Type: blogs

Disruptive Integration and Health Careemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
When Disruptive Integration Comes to Health CarePosted using ShareThisInteresting article containing an interview with Dr. Jason Hwang co-author of The Innovator’s Prescription: A Disruptive Solution for Health Care (McGraw-Hill, 2009).It got me thinking about niches where "disruptive innovation" may occur in laboratory medicine and pathology.  Please share any thoughts you may have--let's get a conversation started about this!One area is lab testing for wellness or serial monitoring of chronic diseases managed on an outpatient basis.  The traditional hospital-based lab (like mine) just has not ...
Source: The Daily Sign-Out - March 5, 2010 Category: Pathologists Authors: Mark D. Pool, M.D. Tags: Health Care Policy Integrated Diagnostics Medicine 2.0 Source Type: blogs

Google Health gains partnersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CNet reports Google Health gains partners:Google is moving forward in the booming health care technology market. The search giant this week announced several new partnerships designed to expand its free Google Health service. Google Health is the company's attempt to offer an online medical portal where you can research medical conditions and issues, find doctors and health care professionals, and track down other health-related Web sites. You can also compile and store a health profile by adding test results, names of medications, insurance information, and electronic medical records from your computer or f...
Source: The Daily Scan - March 5, 2010 Category: Pathologists Authors: Ole Eichhorn Source Type: blogs

Assessing the "True Cost" of Clinical Lab Testingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dr. Brian Jackson has raised a very interesting discussion topic, the "true cost" of clinical lab testing (see: ARUP Laboratories Launches Three Tools to Promote Cost-Effective Laboratory Testing). This goes to the very heart of the cost-effectiveness of lab testing. Below is an excerpt from the article which is self-explanatory: According to Brian Jackson, MD, MS, ARUP’s medical director of medical informatics, the true cost of a diagnostic test includes many factors beyond the direct price of performing the test. For example, an apparently inexpensive test, ordered in the wrong clinical setting or at the wron...
Source: Lab Soft News - March 5, 2010 Category: Pathologists Authors: Bruce Friedman Tags: Clinical Lab Industry News Clinical Lab Testing Lab Processes and Procedures Laboratory Industry Trends Source Type: blogs

An unusual case of CADASIL? Or something else?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
I recently did a brain autopsy on a 70-year-old woman who died from an intraparenchymal brain hemorrhage after a seven-year history of progressive dementia. The gross photograph follows: I know what you’re thinking: an amyloid angiopathic bleed, or perhaps a hypertensive bleed, in a patient with Alzheimer disease. That’s what I was thinking until I saw in the chart that abnormal white matter changes on MRI prompted the neurologist to order Notch3 genetic testing on the patient, which surprisingly came back positive for a mutation. The patient therefore carried a clinical diagnosis of Cerebral Autosomal Dominan...
Source: pathtalk.org - March 4, 2010 Category: Pathologists Authors: Brian Moore Tags: Autopsy General Neuropathology Source Type: blogs

An case of CADASIL? Or something else?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
I recently did a brain autopsy on a 70-year-old woman who died from an intraparenchymal brain hemorrhage after a seven-year history of progressive dementia. The gross photograph follows: I know what you’re thinking: an amyloid angiopathic bleed, or perhaps a hypertensive bleed, in a patient with Alzheimer disease. That’s what I was thinking until I saw in the chart that abnormal white matter changes on MRI prompted the neurologist to order Notch3 genetic testing on the patient, which surprisingly came back positive for a mutation. The patient therefore carried a clinical diagnosis of Cerebral Autosomal Dominant...
Source: pathtalk.org - March 4, 2010 Category: Pathologists Authors: Brian Moore Tags: Autopsy General Neuropathology Source Type: blogs

Prostatic Cancer Metastases May Be Programmed by a Single Gene -- EZH2email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
One of the challenges of clinical oncology has been that some cancer patients are being overtreated. Their tumors may have a biologic nature such that they remain quiescent for long periods of time. However, patients with such lesions are often treated in the same fashion as patients with more aggressive lesions. With current surgical pathology techniques, malignant tumors incapable of metastasizing often cannot be distinguished from those that have this capacity. This knowledge gap may soon be resolved, at least for prostatic cancer (see: Advance Toward Test for Aggressive Prostate Cancer). Below is an excerpt from this a...
Source: Lab Soft News - March 4, 2010 Category: Pathologists Authors: Bruce Friedman Tags: Clinical Lab Industry News Clinical Lab Testing Laboratory Industry Trends Medical Research Surgical Pathology Source Type: blogs

An unusual case of CADASIL? Or something else?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
I recently did a brain autopsy on a 70-year-old woman who died from an intraparenchymal brain hemorrhage after a seven-year history of progressive dementia. The gross photograph (provided by Chad Jeffers, Memorial Medical Center, Springfield, IL)  follows:I know what you're thinking: an amyloid angiopathic bleed, or perhaps a hypertensive bleed, in a patient with Alzheimer disease. That's what I was thinking until I saw in the chart that abnormal white matter changes on MRI prompted the neurologist to order Notch3 genetic testing on the patient, which surprisingly came back positive for a mutation. The patient therefo...
Source: neuropathology blog - March 4, 2010 Category: Pathologists Tags: vascular disease Alzheimer's disease Source Type: blogs

An case of CADASIL? Or something else?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
I recently did a brain autopsy on a 70-year-old woman who died from an intraparenchymal brain hemorrhage after a seven-year history of progressive dementia. The gross photograph (provided by Chad Jeffers, Memorial Medical Center, Springfield, IL)  follows:I know what you're thinking: an amyloid angiopathic bleed, or perhaps a hypertensive bleed, in a patient with Alzheimer disease. That's what I was thinking until I saw in the chart that abnormal white matter changes on MRI prompted the neurologist to order Notch3 genetic testing on the patient, which surprisingly came back positive for a mutation. The patient therefo...
Source: neuropathology blog - March 4, 2010 Category: Pathologists Tags: vascular disease Alzheimer's disease Source Type: blogs

Updates on respiratory bronchiolitis/interstitial lung diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study consisted of 23 consecutive lobectomy specimens for malignant neoplasms with extensive and systematic sampling of non-neoplastic lung (27 sections per case!).  None of the patients had clinical evidence of ILD.  Also, all patients had CT scans but none showed radiographic evidence of diffuse ILD.  20/23 patients were smokers, 10 current.  One interesting point in this article is the proportion of women to men: 15 subjects were women versus 8 men.  This seems unusual both in terms of a series of lobectomies for malignancy as well as a study of ILD since men are usually more com...
Source: The Daily Sign-Out - March 3, 2010 Category: Pathologists Authors: Mark D. Pool, M.D. Tags: Interstitial Lung Disease Source Type: blogs

Omnyx Licenses Olympus Digital Pathology Patentsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
: Olympus America Inc. has signed a nonexclusive worldwide licensing agreement with Omnyx, LLC, a joint venture of GE Healthcare and the University of Pittsburgh Medical Center, allowing Omnyx to access an extensive portfolio of Olympus America patents in the field of virtual microscopy and digital pathology, to help develop solutions in the digital pathology field. The agreement helps clear the path for future imaging and data handling technologies that may one day facilitate the way doctors review and manage millions of biopsy slides and other pathology specimens now handled using glass slides and traditional optical mi...
Source: The Daily Scan - March 3, 2010 Category: Pathologists Authors: Ole Eichhorn Source Type: blogs

Undercover Bossemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Editor's note: The following is a guest blog by Amanda Koehler, our colleague over at ADVANCE for Medical Laboratory Technologists. CBS recently starting airing its new series called Undercover Boss . Based on a similar British series, it features company...(read more) (Source: ADVANCE Discourse: Lab)
Source: ADVANCE Discourse: Lab - March 3, 2010 Category: Pathologists Authors: Kelly Graham Tags: Practice/Business Management Source Type: blogs

An Explanation for the "Invisibility" of LIS and PACS Vendors at HIMSSemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Michael Cannavo recently used HIStalk as a forum to ask the following interesting question: why are PACS vendors and topics almost invisible at HIMSS? (See: Imaging Decisions Demand Up to Date Information). I will expand his question to include the question of why HIMSS also ignores the LIS world about which I have a better understanding. Below is an excerpt from his note:Five years ago, I was approached by a PACS vendor to put together a presentation for IT folks at HIMSS. We did the presentation titled Everything IT Needs to Know About PACS (but is afraid to ask) off-site and had 75 people there. Why off-site? The vendor...
Source: Lab Soft News - March 3, 2010 Category: Pathologists Authors: Bruce Friedman Tags: Electronic Medical Record Healthcare Business Healthcare Information Technology Hospitals and Healthcare Delivery Imaging Other Than Pathology Lab Information Products Source Type: blogs

Mayo cytogenetics pioneer passes awayemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
While I never had the fortune of working with Dr. Dewald, his reputation preceded him.  There are countless stories about his dedication and devotion to clinical cytogenetics.  Full obituary in local Rochester, MN newspaper. (Source: Digital Pathology Blog)
Source: Digital Pathology Blog - March 3, 2010 Category: Pathologists Authors: Kaps Source Type: blogs

High Grade Prostatic Intraepithelial Neoplasia (HGPIN)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
: Common questions asked about HGPIN are : -How do we as pathologists make these diagnoses? -What do they mean for the patient in terms of cancer risk? -What is/are the optimal strategies for follow-up so that if cancer does eventually develop it is caught at an early, curable stage? These questions are shortly discussed at www.oncopathology.blogspot.com (Source: pathtalk.org)
Source: pathtalk.org - March 2, 2010 Category: Pathologists Authors: Prashant Jani Tags: General Source Type: blogs

High Grade Prostatic Intraepithelial Neoplasia (HGPIN)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
:Common questions asked about HGPIN are :-How do we as pathologists make these diagnoses?-What do they mean for the patient in terms of cancer risk?-What is/are the optimal strategies for follow-up so that if cancer does eventually develop it is caught at an early, curable stage?Pathology criteria fro diagnosis of HGPIN:-Architecturally benign acini/ducts lined by atypical cells.-These cells show large nuclei and prominent nucleoli (cytologic features of carcinoma).-Generally at least 10% of the luminal cells should show these features to make the diagnosis. Diagnosis of HGPIN has been shown to be reproducible. Low grade p...
Source: Oncopathology - March 2, 2010 Category: Pathologists Tags: High Grade Prostatic Intraepithelial Neoplasia (HGPIN) Source Type: blogs

Why understanding medical risk is key to US health reformemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The McKinsey Quarterly has posted an interesting analysis: Why understanding medical risk is key to US health reform (PDF). The fundamental nature of medical risk in the United States has changed over the past 20 to 30 years — shifting away from random, infrequent, and catastrophic events driven by accidents, genetic predisposition, or contagious disease and toward behavior- and lifestyle-induced chronic conditions.  Treating them, and the serious medical events they commonly induce, now costs more than treating the more random, catastrophic events that health insurance was originally designed to cover. What’s mo...
Source: The Daily Scan - March 2, 2010 Category: Pathologists Authors: Jared Schwartz Source Type: blogs

Rigged Depression Survey on the Web Steers Readers to Lilly's Cymbaltaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
It seems to me that there's no obvious end-point to the dirty tricks that pharmaceutical companies will attempt to flog their products. I have previously raised the issues of under-the-table payments to physicians for presenting biased lectures (see: Medical Schools Share Some Blame in Scandals Involving Pharma Payments to Faculty), ghostwritten articles in medical journals steering physicians to certain drugs (see: Details Emerge About Ghost-Written Medical Articles for Wyeth), and even a phony medical journal created from scratch by a pharmaceutical company (see: Merck Creates Phony Peer-Reviewed Medical Journal to D...
Source: Lab Soft News - March 2, 2010 Category: Pathologists Authors: Bruce Friedman Tags: Medical Consumerism Medical Education Medical Ethics Source Type: blogs

Aperio Appoints a COOemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Recently Aperio named a Chief Medical Officer (Dr. Jared Schwartz) and now appoints a Chief Operating Officer, Keith B. Hagen: (Source: Digital Pathology Blog)
Source: Digital Pathology Blog - March 2, 2010 Category: Pathologists Authors: Kaps Source Type: blogs

Case of the Week 44email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The following object was found in the diaper of a 1 year old female. The mother noted that it was moving when found. Identification? (Source: pathtalk.org)
Source: pathtalk.org - March 1, 2010 Category: Pathologists Authors: Bobbi Pritt Tags: Cases Microbiology Source Type: blogs

Answer to Case of the Week 43email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Answer: Schistosoma mansoni eggs This case seemed to generate a lot of enthusiasm from the audience. Thank you all for the great comments! The eggs shown here are classic for S. mansoni, with their large size (>150 microns largest dimension) and classic lateral spine. Chris C. asked how I thought to do the squash preparation on this tissue. The answer is that this tissue was submitted specifically to look for Schistosoma eggs. As you can imagine, this is a rare request when you practice in an area that does not have endemic schistosomiasis. However, we do on occasion receive rectal biopsies in microbiology for this techni...
Source: pathtalk.org - March 1, 2010 Category: Pathologists Authors: Bobbi Pritt Tags: Cases Microbiology Source Type: blogs

chalk tip #35: setting image resolutionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Greetings all... Did you know?  In ImageScope, it is easy to set image resolution.  I'm going to show you *how* easy, and I'll talk a little bit about what image resolution is, too... First, what *is* image resolution?  Every image represents something with little dots called pixels.  Image resolution is simply the size which each pixel represents.  For example, suppose you had a picture which was 5" x 7" in dimension.  Maybe it consists of 1,500 x 2,100 pixels, so that each pixel represents 1/300th of an inch.  For this case the resolution of the image is 1/300...
Source: The Daily Scan - March 1, 2010 Category: Pathologists Authors: Ole Eichhorn Tags: chalk tips Source Type: blogs

Trastumuzab approved for treatment of HER2-positiveemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
from primeLines:"On December 17, 2009, Roche’s trastuzumab (Herceptin®) received a positive recommendation from the European Medicines Agency (EMEA) for use in combination with standard chemotherapy for the treatment of previously untreated patients with HER2-positive metastatic adenocarcinoma of the stomach or gastroesophageal junction. The positive opinion for this new indication was issued in record time due to high unmet medical need and data from the ToGA trial (my emphasis), which demonstrated an increase in overall survival (OS) for patients with advanced HER2-positive gastric cancer who received trastuzumab...
Source: The Daily Sign-Out - March 1, 2010 Category: Pathologists Authors: Mark D. Pool, M.D. Tags: Gastric cancer Molecular Pathology Prognostic/Predictive Cancer Markers Source Type: blogs

Case of the Week 107email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The following object was found in the diaper of a 1 year old female. The mother noted that it was moving when found. Identification? (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - March 1, 2010 Category: Pathologists Source Type: blogs

Did Google Change Its Search Algorithm in Early February?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
I have a hunch that Google may have changed its search algorithm in early February in a way that is favorable for Lab Soft News. Here's what I have been seeing on the blog in terms of inbound traffic, which is to say readers who are referred by a Google search or who navigate directly to the site. This is in contrast to the majority of readers who subscribe to the blog or follow it on Twitter and then read the notes via email, with an RSS news consolidator, or in Twitter. Beginning on February 2, 2010, my total inbound traffic has increased by about 70% in a steeply ascending curve. In the more than four years that I h...
Source: Lab Soft News - March 1, 2010 Category: Pathologists Authors: Bruce Friedman Tags: Blogosphere and Websphere Information Technology Web and Browsers Source Type: blogs

Answer to Case 107email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Well, this was definitely a challenging case this week! Many of you wrote in with suggestions that this is some type of fly larvae, and that is certainly a good thought. However, there are no structures such as spines or mouth parts to confirm this identity, and the history would be a bit odd. Instead, this is actually a proglottid of Dipylidium caninum, the double-pored dog tapeworm. Although classically likened to "grains of rice," mature and gravid proglottids have been described as "pumpkin seed" shaped (as seen here). The diagnosis is confirmed by identifying the characteristic egg packets of D. caninum. This can be a...
Source: Creepy Dreadful Wonderful Parasites - March 1, 2010 Category: Pathologists Source Type: blogs

Omnyx Licenses Olympus Digital Pathology Patentsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Interesting news from Omnyx and Olympus.  Think these types of agreements are of benefit to the digital pathology space. (Source: Digital Pathology Blog)
Source: Digital Pathology Blog - March 1, 2010 Category: Pathologists Authors: Kaps Source Type: blogs

First credit 5email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This is the fifth and last in a multi-part blog on the topic of FIRST CREDIT in the sciences.Sometimes, credit falls on the person who least understood the significance of his own work. In 1771, Charles Messier (1730 - 1817) , selected 103 heavenly objects that have captured the rapt attention of astronomers for nearly two and a half centuries. Messier selected regions of space that were nebulous, and obscured his view of comets (his sole interest). He made a point of categorizing the Messier objects as areas of space that should be avoided by serious astronomers. In 1771, his chosen spots might have been accurately called...
Source: Specified Life - February 28, 2010 Category: Pathologists Tags: first credit Source Type: blogs

MedPage Today Articleemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
I thought you would like to read the linked article: Extent of Lymph Node Resection Key to Endometrial CA Survival (CME/CE) Visit MedPage Today now. At MedPage Today, we are Putting Breaking Medical News into Practice(R). Sent from my iPhone (Source: The Daily Sign-Out)
Source: The Daily Sign-Out - February 27, 2010 Category: Pathologists Authors: Mark D. Pool, M.D. Source Type: blogs

First credit 4email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This is the fourth in a multi-part blog on the topic of FIRST CREDIT in the sciences.Johann Franz Encke (1791 - 1865) is given credit for the discovery of [Encke's] comet (1818), but Encke merely calculated the orbit, using a technique first developed more than a century earlier by Edmond Halley (1656-1742). In 1705, Halley applied Newton's laws of physics to correctly predict that a particular comet (known today as Halley's comet), observed in 1531, 1607, and 1682, would return in 1758. The comet known today as Encke's comet was named after a person who neither first-sighted the comet nor discovered the methodology to pre...
Source: Specified Life - February 27, 2010 Category: Pathologists Tags: first credit Source Type: blogs

Definiens has been selected to appear on 21st Century Health Television seriesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Press Release about Definiens: (Source: Digital Pathology Blog)
Source: Digital Pathology Blog - February 27, 2010 Category: Pathologists Authors: Kaps Source Type: blogs

Simple "Chip" Could Revolutionize Third World Diagnosticsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
George Whitesides, a chemistry professor at Harvard University, sees great beauty and possibility in simplicity. He’s also got a passion for bringing diagnostics to underprivileged, overpopulated areas. Laboratorians have heard talk of lab-on-a-chip technology...(read more) (Source: ADVANCE Discourse: Lab)
Source: ADVANCE Discourse: Lab - February 26, 2010 Category: Pathologists Authors: Kelly Graham Tags: Current Events Point-of-Care Testing Source Type: blogs

An Analysis of Digital Collaboration in the Context of Integrated Diagnosticsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
I recently participated in a wide-ranging discussion about integrated diagnostics and the term digital collaboration cropped up. I had not heard if before so I thought it would be useful to analyze it in this context. Integrated diagnostics refers to the closer collaboration, or even eventual merger, of the diagnostic specialties, particularly lab  medicine, pathology, and radiology.To get the ball rolling, digital collaboration can be defined in the following way: working together [by] sharing ideas and [information] using online technology. What then is its relevance with regard to the emerging closer collaboration...
Source: Lab Soft News - February 26, 2010 Category: Pathologists Authors: Bruce Friedman Tags: Anatomic Pathology Digital Imaging in Pathology Electronic Medical Record Healthcare Information Technology Imaging Other Than Pathology Lab Information Products Laboratory Industry Trends Surgical Pathology Source Type: blogs