Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Immunosuppressive protocols after laryngeal transplantation: a systematic review
CONCLUSIONS: Beyond the surgical prowess, larynx transplantation is feasible and associated with a reasonably successful outcome when compared to other solid organ transplants. Immunosuppressive regimen protocols and technologies for the monitoring of the organ viability have evolved.SIGNIFICANCE: The reevaluation of this surgical option serves as the reminder of the critical necessity to implement a meticulous immunosuppression protocol when transplanting this inherently immunogenic composite organ, the larynx.PMID:38662869 | DOI:10.1080/00016489.2024.2339341 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 25, 2024 Category: ENT & OMF Authors: Robin Baudouin Florent Von Tokarski Tiffany Rigal Anna Crambert Alexandre Hertig St éphane Hans Source Type: research

Measurement of stapes footplate thickness using ultra-high-resolution computed tomography: stapes axial plane correlates better with otosclerosis than lateral semicircular canal plane
CONCLUSION: The stapes footplate was thickened at its AC in otosclerosis patients using only the stapes axial plane.SIGNIFICANCE: We propose to use the stapes axial plane instead of the lateral semicircular canal plane when analyzing the stapes.PMID:38662875 | DOI:10.1080/00016489.2024.2340083 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 25, 2024 Category: ENT & OMF Authors: Romain Gillet Michael Eliezer Gabriela Hossu Charles Lombard Fatma Boubaker Alain Blum Pedro Augusto Gondim Teixeira C écile Parietti-Winkler Source Type: research

Evaluation of magnetic resonance imaging to detect cholesteatoma in clinical healthcare
CONCLUSIONS AND SIGNIFICANCE: There is a clear annual trend with increased numbers of executed examinations during the study period. The diagnostic accuracy of non-EPI DW MRI does not reach acceptable levels in the existing everyday routine practice conditions. The accuracy of the examination increases when interpreted by an experienced radiologist and when using the definition of cholesteatoma recommended by EAONO/JOS.PMID:38662877 | DOI:10.1080/00016489.2024.2344820 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 25, 2024 Category: ENT & OMF Authors: Eleonor Koro Emely Ögren Katarina Olofsson Mimmi Werner Source Type: research

'Precursory symptoms, awareness or progression of facial palsy' are more useful than 'forehead wrinkling ability' in differentiating central facial palsy examined in the emergency department
CONCLUSIONS AND SIGNIFICANCE: Forehead wrinkling, a traditional CFP sign, is also common in early-stage PFP, decreasing its diagnostic reliability. Patients with solely CFP unable to wrinkle the forehead are very rare at a single institution. Evaluating precursors symptoms, and FP awareness and progression is crucial for differentiation.PMID:38662879 | DOI:10.1080/00016489.2024.2341974 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 25, 2024 Category: ENT & OMF Authors: Shinya Ohira Yusei Yamaguchi Ryosuke Yui Kota Wada Source Type: research

Spatiotemporal expression of AP-2/myosin Ⅵ in mouse cochlear IHCs and correlation with auditory function
CONCLUSIONS AND SIGNIFICANCE: AP-2 and myosin Ⅵ protein expression may differ in mice of different ages, and this variation probably leads to a difference in the efficiency in CME; it may also cause a defect in IHC function.PMID:38662892 | DOI:10.1080/00016489.2024.2341126 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 25, 2024 Category: ENT & OMF Authors: Xiang Gu Ling Lin Source Type: research

Cochlear implantation in patients with < em > Streptococcus suis < /em > meningitis: clinical characteristics and postoperative evaluation
CONCLUSIONS AND SIGNIFICANCE: It is recommended for S. suis meningitis CI candidates to undergo CI promptly after controlling infection, preferably within four to six weeks. CI users with S. suis meningitis tend to exhibit suboptimal hearing rehabilitation outcomes, possibly associated with the more severe damage on spiral ganglion cells after S. suis meningitis.PMID:38651889 | DOI:10.1080/00016489.2024.2323650 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 23, 2024 Category: ENT & OMF Authors: Zhuoyi Chen Minqian Gao Xiaying Huang Xianghui Li Xiaotong Huang Yongkang Ou Yiqing Zheng Haidi Yang Source Type: research

Cochlear implantation in patients with < em > Streptococcus suis < /em > meningitis: clinical characteristics and postoperative evaluation
CONCLUSIONS AND SIGNIFICANCE: It is recommended for S. suis meningitis CI candidates to undergo CI promptly after controlling infection, preferably within four to six weeks. CI users with S. suis meningitis tend to exhibit suboptimal hearing rehabilitation outcomes, possibly associated with the more severe damage on spiral ganglion cells after S. suis meningitis.PMID:38651889 | DOI:10.1080/00016489.2024.2323650 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 23, 2024 Category: ENT & OMF Authors: Zhuoyi Chen Minqian Gao Xiaying Huang Xianghui Li Xiaotong Huang Yongkang Ou Yiqing Zheng Haidi Yang Source Type: research

Cochlear implantation in patients with < em > Streptococcus suis < /em > meningitis: clinical characteristics and postoperative evaluation
CONCLUSIONS AND SIGNIFICANCE: It is recommended for S. suis meningitis CI candidates to undergo CI promptly after controlling infection, preferably within four to six weeks. CI users with S. suis meningitis tend to exhibit suboptimal hearing rehabilitation outcomes, possibly associated with the more severe damage on spiral ganglion cells after S. suis meningitis.PMID:38651889 | DOI:10.1080/00016489.2024.2323650 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 23, 2024 Category: ENT & OMF Authors: Zhuoyi Chen Minqian Gao Xiaying Huang Xianghui Li Xiaotong Huang Yongkang Ou Yiqing Zheng Haidi Yang Source Type: research

Impact of unilateral vs. bilateral evaluation on cochlear implant candidacy
Conclusions and Significance: Expanding the indication criteria opens up the possibility of improving the accurate identification of individual cases suitable for cochlear-implant provision.PMID:38648394 | DOI:10.1080/00016489.2024.2336562 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 22, 2024 Category: ENT & OMF Authors: Ulrich Hoppe Thomas Hocke Anne Hast Source Type: research