The predictors and risk factors of two-year rejection in renal transplant patients: A multicenter case-control study
CONCLUSION: Our findings emphasize the need for appropriate prevention and management of infections following kidney transplantation to avoid more serious problems, such as rejection, which could significantly raise the likelihood of allograft failure and probably death. Further studies with larger sample size are needed to investigate the impact of serum chloride levels prior to transplant and intraoperative hypotension on the risk of rejection.PMID:38679014 | DOI:10.1159/000538963 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - April 28, 2024 Category: Urology & Nephrology Authors: Maram M Alsulami Nouf E Al-Otaibi Walaa A Alshahrani Abdulrahman Altheaby Khalefa M Al Thiab Lina I Alnajjar Mohamed A Albekery Reem F Almutairy Mohammed Y Asiri Sumaya N AlMohareb Faisal Aqeel Alsehli Alanoud T Binthuwaini Alaa Almagthali Sarah S Alwaily Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Proton Pump Inhibitors and Kidney Disease: Fact or Fiction?
Am J Nephrol. 2024 Apr 6. doi: 10.1159/000538755. Online ahead of print.ABSTRACTBACKGROUND: Proton pump inhibitors (PPI) are commonly prescribed medications for dyspepsia and gastroesophageal reflux. There are concerns about their use in the development of chronic kidney disease (CKD).SUMMARY: The available published literature fails to support an association with PPI and the development of CKD. Placebo-controlled trials demonstrate no difference on the incidence of CKD between placebo and PPI. If one examines the data according to the Bradford Hill perspective incorporating temporal relationship, strength of association, ...
Source: American Journal of Nephrology - April 7, 2024 Category: Urology & Nephrology Authors: Matthew Ryan Weir Source Type: research
Association of Sevelamer Initiation with Gastrointestinal Bleeding Hospitalization in Individuals Requiring Hemodialysis
Conclusion Among patients requiring hemodialysis, sevelamer (vs non-sevelamer) containing phosphate binders was not associated with increased risk of GIB hospitalization.PMID:38555633 | DOI:10.1159/000538253 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 31, 2024 Category: Urology & Nephrology Authors: Dustin Le Deidra C Crews Morgan E Grams Josef Coresh Jung-Im Shin Source Type: research
Association of Sevelamer Initiation with Gastrointestinal Bleeding Hospitalization in Individuals Requiring Hemodialysis
Conclusion Among patients requiring hemodialysis, sevelamer (vs non-sevelamer) containing phosphate binders was not associated with increased risk of GIB hospitalization.PMID:38555633 | DOI:10.1159/000538253 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 31, 2024 Category: Urology & Nephrology Authors: Dustin Le Deidra C Crews Morgan E Grams Josef Coresh Jung-Im Shin Source Type: research
Association of Sevelamer Initiation with Gastrointestinal Bleeding Hospitalization in Individuals Requiring Hemodialysis
Conclusion Among patients requiring hemodialysis, sevelamer (vs non-sevelamer) containing phosphate binders was not associated with increased risk of GIB hospitalization.PMID:38555633 | DOI:10.1159/000538253 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 31, 2024 Category: Urology & Nephrology Authors: Dustin Le Deidra C Crews Morgan E Grams Josef Coresh Jung-Im Shin Source Type: research
