Association of Retinal Thickness at Month 1 Post-Treatment with Later Thickness and Visual Acuity in Central Vein Occlusion
: To investigate the association of retinal thickness 1 month post-randomization (1 month after first study injection with aflibercept or bevacizumab) with later retinal thickness, visual acuity, and number of treatments in eyes with central or hemiretinal vein occlusion enrolled in the SCORE2 trial. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 3, 2024 Category: Opthalmology Authors: Ingrid U. Scott, Neal L. Oden, Michael S. Ip, Paul C. VanVeldhuisen, Barbara A. Blodi, SCORE2 Study Investigator Group Source Type: research

Causal Links Between Systemic Disorders and Keratoconus in European Population
The objective of this study was to establish the presence of a causal linkage between prevalent systemic diseases and keratoconus (KC). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 3, 2024 Category: Opthalmology Authors: Xiaxue Chen, Lanlan Chen Tags: Original Articles Source Type: research

Accuracy of Modern Intraocular Lens Formulas in Highly Myopic Eyes Implanted with Plate-Haptic Intraocular Lenses
Since the first successful implantation of an intraocular lens (IOL) by Dr. Harold Ridley in 1949, IOLs and power calculations have evolved over more than 70 years.1 During this period, there have been continual advancements in ocular biometry and IOL formulas, the diversity of IOL types has expanded, and patient expectations for postoperative visual quality have escalated, culminating in a paradigm shift in cataract surgery from purely visual restoration to a refractive procedure. Particularly for patients with high myopia (typically characterized by an axial length (AL) exceeding 26mm), cataract surgery holds dual import...
Source: American Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Er Mo, Zexin Chen, Ke Feng, Zehui Zhu, Jialin Xu, Chenyuan Zhu, Pingjun Chang, Jin Li, Yun-e Zhao Tags: Original Articles Source Type: research

Intraocular immune response in human uveitis: time to look beyond animal models
To review the current and future approaches to investigating the intraocular immune response in human uveitis. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Soumyava Basu, Lynn Hassman, Shilpa Kodati, Colin J Chu Tags: Perspective Source Type: research

Progression or Aging? A Deep Learning Approach for Distinguishing Glaucoma Progression from Age-Related Changes in OCT scans
To develop deep learning (DL) algorithm to detect glaucoma progression using optical coherence tomography (OCT) images, in the absence of a reference standard. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Sayan Mandal, Alessandro A. Jammal, Davina Malek, Felipe A. Medeiros Tags: Original Articles Source Type: research

Reduction of Optic Disc Microvasculature and Retinal Nerve Fiber Layer Thinning in Patients with Glaucoma
To assess the relationship between the change of optic disc vessel density (ODVD) and retinal nerve fiber layer (RNFL) thinning in primary open-angle glaucoma (POAG) patients. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 1, 2024 Category: Opthalmology Authors: Min Hee Suh, Robert N. Weinreb, Linda M. Zangwill, Evan Walke Source Type: research

Importance of Baseline Fluorescein Angiography for Patients Presenting to Tertiary Uveitis Clinic
To ascertain whether the use of ultra-wide-field fluorescein angiography (UWFFA) at baseline visit alters the assessment of disease activity and localization, as well as the management of patients presenting to a tertiary uveitis clinic. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - May 1, 2024 Category: Opthalmology Authors: Irmak Karaca, Albert Bromeo, Hashem Ghoraba, Xun Lyu, Zheng Xian Thng, Cigdem Yasar, Amir Akhavanrezayat, Negin Yavari, Gunay Uludag Kirimli, Ngoc Tuong Trong Than, YongUn Shin, Ankur Sudhir Gupta, Anadi Khatri, S. Saeed Mohammadi, Jia-Horung Hung, Christ Tags: Original Articles Source Type: research

Outcomes of cataract surgery in eyes with axial length > 33 mm
The prevalence of myopia is increasing at an alarming rate worldwide, especially in Asia, and is projected to affect half of the global population by 2050.1 High myopia is defined differently, but is commonly characterized by an axial length (AL) exceeding 26.0 mm.2 As the AL elongates, there are significant changes in ocular structures, which are closely associated with various sight-threatening complications, such as cataract, macular pathologies, choroidal neovascularization, retinal detachment (RD) and glaucoma. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - April 30, 2024 Category: Opthalmology Authors: Yinglei Zhang, Yu Du, Anjian Wang, Xingtao Zhou, Yi Lu, Xiangjia Zhu Tags: Original Articles Source Type: research

Retinal image quality through an operating microscope with wavefront shaping extended depth of focus intraocular lens in model eye
Multifocal intraocular lenses (IOLs) are frequently used after cataract extractions because they reduce the need for spectacles which is convenient for the daily lives of patients.1,2 Multifocal IOLs have either refractive or diffractive optical structures to create multiple focal points.3,4 However, the discontinuous focus created by the multifocal IOLs leads to postoperative dysphotopsia including glare and halos due to light scattering. Extended depth-of-focus (EDoF) IOLs have an elongated focal point which results in an increase in the depth of focus, and they are used for the optical treatment of eyes after cataract e...
Source: American Journal of Ophthalmology - April 30, 2024 Category: Opthalmology Authors: Makoto Inoue, Yuji Itoh, Hiroko Bissen-Miyajima, Takashi Koto Tags: Original Articles Source Type: research

The effect of blue-light filtering intraocular lenses on the development and progression of macular atrophy in eyes with nAMD
To assess the effect of blue-light filtering (BLF) intraocular lenses (IOLs) on the development and progression of macular atrophy (MA) in eyes with neovascular age-related macular degeneration (nAMD). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - April 28, 2024 Category: Opthalmology Authors: Asaf Achiron, Omer Trivizki, Boris Knyazer, Uri Elbaz, Idan Hecht, Sohee Jeon, Piotr Kanclerz, Raimo Tuuminen Source Type: research

Comment on: NSAIDs and corticosteroids for the postoperative management of age-related cataract surgery: a systematic review and meta-analysis
Dear Editor, (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - April 27, 2024 Category: Opthalmology Authors: Kenneth J. Taubenslag, Andrzej Grzybowski, Stephen J. Kim Tags: Correspondence Source Type: research

Automated Bimanual Decompression of Intumescent Cataract: Alternate Solution for Challenging Cases
Video Description: (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - April 26, 2024 Category: Opthalmology Authors: Rajesh Deshmukh, Sam Myers Tags: Illustrations & Insights Source Type: research

Incidence Rate of Secondary Glaucoma Following Congenital Cataract Surgery: An In-Depth Systematic Review and Meta-Analysis
To assess the incidence of secondary glaucoma in children following congenital cataract surgery. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - April 26, 2024 Category: Opthalmology Authors: Li Li, Xi Wang, Changyang Liu, Shuai Wang, Xiaochen Wang Source Type: research

Malignancy Risk Associated with the Use of Systemic Immunomodulatory Therapy in the Management of Non-infectious Uveitis
Patients with non-infectious uveitis (NIU) can require treatment with systemic immunomodulatory therapy (IMT), but it is unclear whether IMT drug categories increase the risk of malignancy in NIU patients. The purpose of this study is to determine if the use of systemic IMT in patients with NIU is associated with an increased risk of malignancy. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: George N. Papaliodis, Yinxi Yu, Daniel A. Brill, Lucia Sobrin, Brian VanderBeek Tags: Original Articles Source Type: research

Alterations of the Ganglion Cell Complex in Age-Related Macular Degeneration: an AMISH Eye Study Analysis
To compare the Ganglion Cell Complex (GCC) thickness in eyes with age-related macular degeneration (AMD) versus healthy controls in an elderly Amish population (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Swetha Bindu Velaga, Ahmed Roshdy Alagorie, Mehdi Emamverdi, Maryam Ashrafkhorasani, Abbas Habibi, Muneeswar Gupta Nittala, Gagan Sing, Jonathan Haines, Margaret A. Pericak-Vance, Dwight Stambolian, Srinivas R. Sadda Tags: Original Articles Source Type: research