Analytical and Bioanalytical Chemistry 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Supramolecular deep eutectic solvent: a powerful tool for pre-concentration of trace metals in edible oil
Anal Bioanal Chem. 2024 May 1. doi: 10.1007/s00216-024-05304-x. Online ahead of print.ABSTRACTThe utilization of supramolecular deep eutectic solvent eddy-assisted liquid-liquid microextraction utilizing 2-hydroxypropyl β-cyclodextrin (SUPRADES) has been identified as a successful method for pre-enriching Cu, Zn, and Mn in vegetable oil samples. Determination of each element was conducted by inductively coupled plasma optical emission spectrometry (ICP-OES) after digestion of metal-enriched phases. Various parameters were examined, including the composition of SUPRADES species [2HP-β-CD: DL-lactic acid], a cyclodextrin m...
Source: Analytical and Bioanalytical Chemistry - May 1, 2024 Category: Chemistry Authors: Peng Sun Chao Wang Shuo Li Nan Li Yuling Gao Source Type: research
A green reaction-based turn-off fluorescence sensor for determination of copper ions: DFT calculations, quenching mechanism, green chemistry metrics, and application in environmental samples
Anal Bioanal Chem. 2024 Apr 29. doi: 10.1007/s00216-024-05293-x. Online ahead of print.ABSTRACTWhen Cu(II) reacts with ascorbic acid (AA) to form Cu(I), Cu(I) can combine with eosin Y (EY) to form ionic associations, resulting in significant fluorescence quenching of the EY. Based on the turn-off of fluorescence in the chemosensor EY, a green reaction is proposed herein for the detection of Cu(II). The novel detection method for Cu(II) demonstrates simplicity, high sensitivity, and excellent selectivity, rendering it suitable for analyzing environmental samples. A static fluorescence quenching mechanism is validated throug...
Source: Analytical and Bioanalytical Chemistry - April 28, 2024 Category: Chemistry Authors: Jian Wang Ling Chen Yanan Li Merilyn Manley-Harris Source Type: research
A green reaction-based turn-off fluorescence sensor for determination of copper ions: DFT calculations, quenching mechanism, green chemistry metrics, and application in environmental samples
Anal Bioanal Chem. 2024 Apr 29. doi: 10.1007/s00216-024-05293-x. Online ahead of print.ABSTRACTWhen Cu(II) reacts with ascorbic acid (AA) to form Cu(I), Cu(I) can combine with eosin Y (EY) to form ionic associations, resulting in significant fluorescence quenching of the EY. Based on the turn-off of fluorescence in the chemosensor EY, a green reaction is proposed herein for the detection of Cu(II). The novel detection method for Cu(II) demonstrates simplicity, high sensitivity, and excellent selectivity, rendering it suitable for analyzing environmental samples. A static fluorescence quenching mechanism is validated throug...
Source: Analytical and Bioanalytical Chemistry - April 28, 2024 Category: Chemistry Authors: Jian Wang Ling Chen Yanan Li Merilyn Manley-Harris Source Type: research
Mixed-phase weak anion-exchange/reversed-phase LC-MS/MS for analysis of nucleotide sugars in human fibroblasts
In conclusion, a novel, semi-quantitative method was established for the analysis of nucleotide sugars that can be applied to diagnose several genetic glycosylation disorders in fibroblasts and beyond.PMID:38676823 | DOI:10.1007/s00216-024-05313-w (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - April 27, 2024 Category: Chemistry Authors: Moritz Rahm Hanneke Kwast Hans J C T Wessels Marek J Noga Dirk J Lefeber Source Type: research
In situ generated CdTe quantum dot-encapsulated hafnium polymer membrane to boost electrochemiluminescence analysis of tumor biomarkers
Anal Bioanal Chem. 2024 Apr 27. doi: 10.1007/s00216-024-05310-z. Online ahead of print.ABSTRACTExploring the construction of an interface with bright emission, fabulous stability, and good function to develop high-performance electrochemiluminescence (ECL) biosensors for tumor biomarkers is in high demand but faces a huge challenge. Herein, we report an oriented attachment and in situ self-assembling strategy for one-step fabrication of CdTe QD-encapsulated Hf polymer membrane onto an ITO surface (Hf-CP/CdTe QDs/APS/ITO). Hf-CP/CdTe QDs/APS/ITO is fascinating with excellent stability, high ECL emission, and specific adsorp...
Source: Analytical and Bioanalytical Chemistry - April 27, 2024 Category: Chemistry Authors: Haiyin Li Zhixin Wang Feng Li Panpan Gai Source Type: research
Mixed-phase weak anion-exchange/reversed-phase LC-MS/MS for analysis of nucleotide sugars in human fibroblasts
In conclusion, a novel, semi-quantitative method was established for the analysis of nucleotide sugars that can be applied to diagnose several genetic glycosylation disorders in fibroblasts and beyond.PMID:38676823 | DOI:10.1007/s00216-024-05313-w (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - April 27, 2024 Category: Chemistry Authors: Moritz Rahm Hanneke Kwast Hans J C T Wessels Marek J Noga Dirk J Lefeber Source Type: research
In situ generated CdTe quantum dot-encapsulated hafnium polymer membrane to boost electrochemiluminescence analysis of tumor biomarkers
Anal Bioanal Chem. 2024 Apr 27. doi: 10.1007/s00216-024-05310-z. Online ahead of print.ABSTRACTExploring the construction of an interface with bright emission, fabulous stability, and good function to develop high-performance electrochemiluminescence (ECL) biosensors for tumor biomarkers is in high demand but faces a huge challenge. Herein, we report an oriented attachment and in situ self-assembling strategy for one-step fabrication of CdTe QD-encapsulated Hf polymer membrane onto an ITO surface (Hf-CP/CdTe QDs/APS/ITO). Hf-CP/CdTe QDs/APS/ITO is fascinating with excellent stability, high ECL emission, and specific adsorp...
Source: Analytical and Bioanalytical Chemistry - April 27, 2024 Category: Chemistry Authors: Haiyin Li Zhixin Wang Feng Li Panpan Gai Source Type: research
Novel dummy molecularly imprinted polymer for simultaneous solid-phase extraction of stanozolol metabolites from urine
In this study, a novel dummy molecularly imprinted polymer (DMIP) is developed as a sorbent for solid-phase extraction of stanozolol metabolites from spiked human urine samples. The optimized DMIP is composed of stanozolol as the dummy template, methacrylic acid as the functional monomer, and ethylene glycol dimethacrylate as the cross-linker in a ratio of 1:10:80. The extracted analytes were quantitively determined using a newly developed and validated ultrahigh-performance liquid chromatography tandem mass spectrometry method, where the limits of detection and quantitation were 0.91 and 1.81 ng mL-1, respectively, fulfil...
Source: Analytical and Bioanalytical Chemistry - April 25, 2024 Category: Chemistry Authors: Yomna G Farag Rasha S Hanafi Mennatallah A Hammam Source Type: research
Challenges faced with 3D-printed electrochemical sensors in analytical applications
Anal Bioanal Chem. 2024 Apr 26. doi: 10.1007/s00216-024-05308-7. Online ahead of print.ABSTRACTPrototyping analytical devices with three-dimensional (3D) printing techniques is becoming common in research laboratories. The attractiveness is associated with printers' price reduction and the possibility of creating customized objects that could form complete analytical systems. Even though 3D printing enables the rapid fabrication of electrochemical sensors, its wider adoption by research laboratories is hindered by the lack of reference material and the high "entry barrier" to the field, manifested by the need to learn how ...
Source: Analytical and Bioanalytical Chemistry - April 25, 2024 Category: Chemistry Authors: Lauro A Pradela-Filho Diele A G Ara újo Vanessa N Ataide Gabriel N Meloni Thiago R L C Paix ão Source Type: research
Novel dummy molecularly imprinted polymer for simultaneous solid-phase extraction of stanozolol metabolites from urine
In this study, a novel dummy molecularly imprinted polymer (DMIP) is developed as a sorbent for solid-phase extraction of stanozolol metabolites from spiked human urine samples. The optimized DMIP is composed of stanozolol as the dummy template, methacrylic acid as the functional monomer, and ethylene glycol dimethacrylate as the cross-linker in a ratio of 1:10:80. The extracted analytes were quantitively determined using a newly developed and validated ultrahigh-performance liquid chromatography tandem mass spectrometry method, where the limits of detection and quantitation were 0.91 and 1.81 ng mL-1, respectively, fulfil...
Source: Analytical and Bioanalytical Chemistry - April 25, 2024 Category: Chemistry Authors: Yomna G Farag Rasha S Hanafi Mennatallah A Hammam Source Type: research
Challenges faced with 3D-printed electrochemical sensors in analytical applications
Anal Bioanal Chem. 2024 Apr 26. doi: 10.1007/s00216-024-05308-7. Online ahead of print.ABSTRACTPrototyping analytical devices with three-dimensional (3D) printing techniques is becoming common in research laboratories. The attractiveness is associated with printers' price reduction and the possibility of creating customized objects that could form complete analytical systems. Even though 3D printing enables the rapid fabrication of electrochemical sensors, its wider adoption by research laboratories is hindered by the lack of reference material and the high "entry barrier" to the field, manifested by the need to learn how ...
Source: Analytical and Bioanalytical Chemistry - April 25, 2024 Category: Chemistry Authors: Lauro A Pradela-Filho Diele A G Ara újo Vanessa N Ataide Gabriel N Meloni Thiago R L C Paix ão Source Type: research
Novel dummy molecularly imprinted polymer for simultaneous solid-phase extraction of stanozolol metabolites from urine
In this study, a novel dummy molecularly imprinted polymer (DMIP) is developed as a sorbent for solid-phase extraction of stanozolol metabolites from spiked human urine samples. The optimized DMIP is composed of stanozolol as the dummy template, methacrylic acid as the functional monomer, and ethylene glycol dimethacrylate as the cross-linker in a ratio of 1:10:80. The extracted analytes were quantitively determined using a newly developed and validated ultrahigh-performance liquid chromatography tandem mass spectrometry method, where the limits of detection and quantitation were 0.91 and 1.81 ng mL-1, respectively, fulfil...
Source: Analytical and Bioanalytical Chemistry - April 25, 2024 Category: Chemistry Authors: Yomna G Farag Rasha S Hanafi Mennatallah A Hammam Source Type: research
Challenges faced with 3D-printed electrochemical sensors in analytical applications
Anal Bioanal Chem. 2024 Apr 26. doi: 10.1007/s00216-024-05308-7. Online ahead of print.ABSTRACTPrototyping analytical devices with three-dimensional (3D) printing techniques is becoming common in research laboratories. The attractiveness is associated with printers' price reduction and the possibility of creating customized objects that could form complete analytical systems. Even though 3D printing enables the rapid fabrication of electrochemical sensors, its wider adoption by research laboratories is hindered by the lack of reference material and the high "entry barrier" to the field, manifested by the need to learn how ...
Source: Analytical and Bioanalytical Chemistry - April 25, 2024 Category: Chemistry Authors: Lauro A Pradela-Filho Diele A G Ara újo Vanessa N Ataide Gabriel N Meloni Thiago R L C Paix ão Source Type: research
Fluorescent carbon dots for labeling of bacteria: mechanism and prospects-a review
Anal Bioanal Chem. 2024 Apr 24. doi: 10.1007/s00216-024-05300-1. Online ahead of print.ABSTRACTThe search for bacteria-labeling agents that are more efficient and less toxic compared to existing staining dyes is ongoing. Fluorescent quantum dots and carbon dots (CDs) have been extensively researched for various bioimaging applications. Priority is given to CDs due to several advantages, including lower toxicity, versatility in tuning their properties, and better photostability compared to metal-based quantum dots. Although significant progress is still needed to replace existing dyes with CDs for bacteria labeling, they of...
Source: Analytical and Bioanalytical Chemistry - April 24, 2024 Category: Chemistry Authors: Anisha Anand Chih-Ching Huang Jui-Yang Lai Darakhshan Bano Helen Indah Pardede Amina Hussain Sehresh Saleem Binesh Unnikrishnan Source Type: research
Extrapolation of cytotoxic masked effects in planar in vitro assays
This study investigates whether these double peaks can be used for fitting a peak function to extrapolate the theoretical, unaffected signals. The precision of the modelling was evaluated for four individual peak functions, using 42 ideal, undistorted peaks from estrogenic model compounds in the p-YES. Modelled ED50-values from bisphenol A (BPA) experiments with cytotoxically disturbed signals were 13 times higher than for the apparent data without compensation for cytotoxicity (320 ± 63 ng versus 24 ± 17 ng). This finding has a high relevance for the modelling of mixture effects according to concentration addition that ...
Source: Analytical and Bioanalytical Chemistry - April 24, 2024 Category: Chemistry Authors: Timothy Rosenberger Anna Maria Bell Georg Reifferscheid Kilian E C Smith Andreas Sch äffer Thomas A Ternes Sebastian Buchinger Source Type: research
