Psychiatrists, outmigration, and the sustainability of the mental health workforce: Insights from a source country - The Philippines
Asian J Psychiatr. 2024 Apr 15;96:104050. doi: 10.1016/j.ajp.2024.104050. Online ahead of print.NO ABSTRACTPMID:38663228 | DOI:10.1016/j.ajp.2024.104050 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - April 25, 2024 Category: Psychiatry Authors: Rowalt Alibudbud Source Type: research

Whole-exome sequencing in a Chinese sample provides preliminary evidence for the link between rare/low-frequency immune-related variants and early-onset schizophrenia
We examined the association of rare or low-frequency deleterious coding variants in Chinese patients with SCZ. We collected DNA samples in 197 patients with SCZ spectrum disorder and 82 healthy controls (HC), and performed exome sequencing. The AAO variable was ascertained in the majority of SCZ participants for identify the early-onset (EOS, AAO<=18) and adult-onset (AOS, AAO>18) subgroups. We examined the overall association of rare/low-frequency, damaging variants in SCZ versus HC, EOS versus HC, and AOS versus HC at the gene and gene-set levels using Sequence Kernel Association Test. The quantitative rare-variant...
Source: Asian Journal of Psychiatry - April 25, 2024 Category: Psychiatry Authors: Yuanxin Zhong Justin D Tubbs Perry B M Leung Na Zhan Tomy C K Hui Karen K Y Ho Karen S Y Hung Eric F C Cheung Hon-Cheong So Simon S Y Lui Pak C Sham Source Type: research

Exploring psychiatric patient restraints: Balancing safety, ethics, and patient rights in mental healthcare
Asian J Psychiatr. 2024 Apr 15;96:104051. doi: 10.1016/j.ajp.2024.104051. Online ahead of print.ABSTRACTRestraint, often linked with limiting an individual's freedom of movement, has become a focal point of extensive discussion and evaluation within the realm of mental healthcare. Striking a delicate balance between ensuring individual safety and minimizing reliance on restraint methods poses a significant challenge. In mental health inpatient settings, the prevalent forms of restraint encompass physical, chemical, environmental, and psychological methods. Paradoxically, the consequences of employing restraint can be sever...
Source: Asian Journal of Psychiatry - April 21, 2024 Category: Psychiatry Authors: Fayaz Ahmad Paul Aasim Ur Rehman Ganie Danishwar Rasool Dar Priyanka Saikia Indrajeet Banerjee Source Type: research

Prevalence and validity of ICD-11 posttraumatic stress disorder (PTSD) and complex PTSD: A population-based survey of Hong Kong adults
Asian J Psychiatr. 2024 Apr 10;96:104045. doi: 10.1016/j.ajp.2024.104045. Online ahead of print.ABSTRACTThe present study aimed to report the prevalence of ICD-11 posttraumatic stress disorder (PTSD) and complex PTSD (CPTSD) in the general adult Hong Kong population, and examine the validity of the Chinese International Trauma Questionnaire (ITQ). This descriptive cross-sectional population-based telephone survey included a representative sample of 1070 non-institutionalized permanent Hong Kong residents ages 18-64 years. Participants provided responses to the Chinese version of the ITQ, and measures of adverse childhood e...
Source: Asian Journal of Psychiatry - April 21, 2024 Category: Psychiatry Authors: Grace W K Ho Ko Ling Chan Thanos Karatzias Philip Hyland Hong Wang Fung Mark Shevlin Source Type: research

Exploring psychiatric patient restraints: Balancing safety, ethics, and patient rights in mental healthcare
Asian J Psychiatr. 2024 Apr 15;96:104051. doi: 10.1016/j.ajp.2024.104051. Online ahead of print.ABSTRACTRestraint, often linked with limiting an individual's freedom of movement, has become a focal point of extensive discussion and evaluation within the realm of mental healthcare. Striking a delicate balance between ensuring individual safety and minimizing reliance on restraint methods poses a significant challenge. In mental health inpatient settings, the prevalent forms of restraint encompass physical, chemical, environmental, and psychological methods. Paradoxically, the consequences of employing restraint can be sever...
Source: Asian Journal of Psychiatry - April 21, 2024 Category: Psychiatry Authors: Fayaz Ahmad Paul Aasim Ur Rehman Ganie Danishwar Rasool Dar Priyanka Saikia Indrajeet Banerjee Source Type: research

Prevalence and validity of ICD-11 posttraumatic stress disorder (PTSD) and complex PTSD: A population-based survey of Hong Kong adults
Asian J Psychiatr. 2024 Apr 10;96:104045. doi: 10.1016/j.ajp.2024.104045. Online ahead of print.ABSTRACTThe present study aimed to report the prevalence of ICD-11 posttraumatic stress disorder (PTSD) and complex PTSD (CPTSD) in the general adult Hong Kong population, and examine the validity of the Chinese International Trauma Questionnaire (ITQ). This descriptive cross-sectional population-based telephone survey included a representative sample of 1070 non-institutionalized permanent Hong Kong residents ages 18-64 years. Participants provided responses to the Chinese version of the ITQ, and measures of adverse childhood e...
Source: Asian Journal of Psychiatry - April 21, 2024 Category: Psychiatry Authors: Grace W K Ho Ko Ling Chan Thanos Karatzias Philip Hyland Hong Wang Fung Mark Shevlin Source Type: research

Exploring psychiatric patient restraints: Balancing safety, ethics, and patient rights in mental healthcare
Asian J Psychiatr. 2024 Apr 15;96:104051. doi: 10.1016/j.ajp.2024.104051. Online ahead of print.ABSTRACTRestraint, often linked with limiting an individual's freedom of movement, has become a focal point of extensive discussion and evaluation within the realm of mental healthcare. Striking a delicate balance between ensuring individual safety and minimizing reliance on restraint methods poses a significant challenge. In mental health inpatient settings, the prevalent forms of restraint encompass physical, chemical, environmental, and psychological methods. Paradoxically, the consequences of employing restraint can be sever...
Source: Asian Journal of Psychiatry - April 21, 2024 Category: Psychiatry Authors: Fayaz Ahmad Paul Aasim Ur Rehman Ganie Danishwar Rasool Dar Priyanka Saikia Indrajeet Banerjee Source Type: research

Prevalence and validity of ICD-11 posttraumatic stress disorder (PTSD) and complex PTSD: A population-based survey of Hong Kong adults
Asian J Psychiatr. 2024 Apr 10;96:104045. doi: 10.1016/j.ajp.2024.104045. Online ahead of print.ABSTRACTThe present study aimed to report the prevalence of ICD-11 posttraumatic stress disorder (PTSD) and complex PTSD (CPTSD) in the general adult Hong Kong population, and examine the validity of the Chinese International Trauma Questionnaire (ITQ). This descriptive cross-sectional population-based telephone survey included a representative sample of 1070 non-institutionalized permanent Hong Kong residents ages 18-64 years. Participants provided responses to the Chinese version of the ITQ, and measures of adverse childhood e...
Source: Asian Journal of Psychiatry - April 21, 2024 Category: Psychiatry Authors: Grace W K Ho Ko Ling Chan Thanos Karatzias Philip Hyland Hong Wang Fung Mark Shevlin Source Type: research

Changes in psychopharmacotherapy for patients with schizophrenia in a psychiatric institution in Japan: A 12-year prescription survey pre- and post-introduction of clozapine
Asian J Psychiatr. 2024 Apr 9;96:104047. doi: 10.1016/j.ajp.2024.104047. Online ahead of print.ABSTRACTPsychopharmacotherapy for patients with schizophrenia in Japan has a long history of polypharmacy, which is rare worldwide but remains a critical problem. One reason for this is that clozapine was not available in Japan until 2009. We aimed to investigate the changes in psychopharmacotherapy in patients with schizophrenia over 12 years pre- and post-introduction of clozapine to clarify how psychopharmacotherapy for patients with schizophrenia has changed with the introduction of clozapine. We retrospectively collected dat...
Source: Asian Journal of Psychiatry - April 19, 2024 Category: Psychiatry Authors: Kohei Kitagawa Shusuke Uekusa Yuki Hanai Itsuki Kimura Masaru Tsukahara Azusa Kagawa Kenji Sasaoka Yui Sakishiro Ayaka Miyake Yuki Watanabe Daiki Baba Masafumi Kodama Yoshiki Kishi Norihito Yamada Takashi Yoshio Kazuhiro Matsuo Source Type: research

Not reinventing the wheel: Nesting suicide prevention and awareness activities within existing health programs
Asian J Psychiatr. 2024 Apr 16;96:104049. doi: 10.1016/j.ajp.2024.104049. Online ahead of print.NO ABSTRACTPMID:38640550 | DOI:10.1016/j.ajp.2024.104049 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - April 19, 2024 Category: Psychiatry Authors: Jilisha Gnanadhas Anish V Cherian Sujita Kumar Kar Vikas Menon Source Type: research

Subregional thalamic functional connectivity abnormalities and cognitive impairments in first-episode schizophrenia
CONCLUSION: Our findings suggest FC abnormalities between thalamic subregions and cortical areas in FES patients. Increased FC correlated with cognitive deficits and negative symptoms, highlighting the importance of thalamo-cortical connectivity in the pathophysiology of schizophrenia.PMID:38615577 | DOI:10.1016/j.ajp.2024.104042 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - April 14, 2024 Category: Psychiatry Authors: Li-Na Wang Shuo Lin Lu Tian Han Wu Wen-Qing Jin Wen Wang Wei-Gang Pan Chun-Lin Yang Yan-Ping Ren Xin Ma Yi-Lang Tang Source Type: research

The co-occurrence of multiple sclerosis and bipolar disorder: A case series on clinical and neuroimaging correlates
We describe the clinical profile and neuroimaging findings of four cases of MS with BD. Among them, two patients had multiple mood episodes preceding the neurological symptoms, one had concurrent manic and neurological symptoms, and one had multiple depressive episodes and an isolated steroid-induced manic episode. Frontal and temporal lobes, and Periventricular White Matter were involved in all four cases, and hence may be considered biological substrates of BD in MS. Larger studies are needed to validate the utility of these findings.PMID:38615578 | DOI:10.1016/j.ajp.2024.104041 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - April 14, 2024 Category: Psychiatry Authors: Harkishan Mamtani Kshiteeja Jain Preethi Reddy Rashmi Arasappa Sundarnag Ganjekar Harish Thippeswamy Maya Bhat M Netravathi Geetha Desai Source Type: research

Subregional thalamic functional connectivity abnormalities and cognitive impairments in first-episode schizophrenia
CONCLUSION: Our findings suggest FC abnormalities between thalamic subregions and cortical areas in FES patients. Increased FC correlated with cognitive deficits and negative symptoms, highlighting the importance of thalamo-cortical connectivity in the pathophysiology of schizophrenia.PMID:38615577 | DOI:10.1016/j.ajp.2024.104042 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - April 14, 2024 Category: Psychiatry Authors: Li-Na Wang Shuo Lin Lu Tian Han Wu Wen-Qing Jin Wen Wang Wei-Gang Pan Chun-Lin Yang Yan-Ping Ren Xin Ma Yi-Lang Tang Source Type: research

The co-occurrence of multiple sclerosis and bipolar disorder: A case series on clinical and neuroimaging correlates
We describe the clinical profile and neuroimaging findings of four cases of MS with BD. Among them, two patients had multiple mood episodes preceding the neurological symptoms, one had concurrent manic and neurological symptoms, and one had multiple depressive episodes and an isolated steroid-induced manic episode. Frontal and temporal lobes, and Periventricular White Matter were involved in all four cases, and hence may be considered biological substrates of BD in MS. Larger studies are needed to validate the utility of these findings.PMID:38615578 | DOI:10.1016/j.ajp.2024.104041 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - April 14, 2024 Category: Psychiatry Authors: Harkishan Mamtani Kshiteeja Jain Preethi Reddy Rashmi Arasappa Sundarnag Ganjekar Harish Thippeswamy Maya Bhat M Netravathi Geetha Desai Source Type: research

Subregional thalamic functional connectivity abnormalities and cognitive impairments in first-episode schizophrenia
CONCLUSION: Our findings suggest FC abnormalities between thalamic subregions and cortical areas in FES patients. Increased FC correlated with cognitive deficits and negative symptoms, highlighting the importance of thalamo-cortical connectivity in the pathophysiology of schizophrenia.PMID:38615577 | DOI:10.1016/j.ajp.2024.104042 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - April 14, 2024 Category: Psychiatry Authors: Li-Na Wang Shuo Lin Lu Tian Han Wu Wen-Qing Jin Wen Wang Wei-Gang Pan Chun-Lin Yang Yan-Ping Ren Xin Ma Yi-Lang Tang Source Type: research