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Common P-glycoprotein ( ABCB1 ) polymorphisms do not seem to be associated with the risk of rivaroxaban-related bleeding events: Preliminary data
CONCLUSIONS: The evaluated common ABCB1 polymorphisms do not seem to affect the risk of early bleeding in patients started on rivaroxaban.PMID:38665866 | PMC:PMC11042566 | DOI:10.11613/BM.2024.020703 (Source: Biochemia Medica)
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Ana Marija Sli šković Jozefina Pali ć Tamara Bo žina Lana Ganoci Majda Vrki ć Kirhmajer Vladimir Trkulja Jo ško Bulum Livija Šimičević Source Type: research

CLSI-based verification and de novo establishment of reference intervals for common biochemical assays in Croatian newborns
CONCLUSIONS: The CALIPER reference intervals can be implemented into routine laboratory and clinical practice for the tested newborn population for most of the analyzed assays, while own reference intervals for potassium, magnesium and direct bilirubin have been determined.PMID:38665867 | PMC:PMC11042559 | DOI:10.11613/BM.2024.020705 (Source: Biochemia Medica)
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Iva Fri ščić Sonja Perkov Andrea Radeljak Jasminka Stipanovi ć-Kastelić Mirjana Mariana Kardum Paro Source Type: research

A case report of biclonal immunoglobulin D lambda/lambda multiple myeloma in patient with liver echinococcosis
Biochem Med (Zagreb). 2024 Jun 15;34(2):020801. doi: 10.11613/BM.2024.020801. Epub 2024 Apr 15.ABSTRACTLess than 2% of all symptomatic multiple myeloma (MM) has immunoglobulin D (IgD) as monoclonal protein. Biclonal gammopathy is much rarer. At the time of diagnosis, disease is often in advanced stage, including renal failure, anemia, hypercalcemia and lytic bone lesions. Due to the rarity of myeloma itself, but also due to the fact that anti-IgD antisera is not used in routine practice, there are only a few reports of IgD MM described in the literature. This case report describes a patient with IgD lambda MM with anemia a...
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Andrea Prce Željka Dunđerović Ivanka Mikuli ć Vinka Mikuli ć Kristina Ljubi ć Ana Ćuk Ante Bogut Josip Petrovi ć Mile Volari ć Tomislav Čolak Fila Ragu ž Source Type: research

Corrigendum to: Negligible effect of vitamin D supplementation on exacerbation in patients with chronic obstructive pulmonary disease: meta-analysis
Biochem Med (Zagreb). 2024 Jun 15;34(2):021201. doi: 10.11613/BM.2024.021201.ABSTRACT[This corrects the article , PMID: 37841773.].PMID:38665869 | PMC:PMC11042563 | DOI:10.11613/BM.2024.021201 (Source: Biochemia Medica)
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Ye Hua Ting Jiang Jiangyi Feng Mi Zou Source Type: research

Quality assurance of add-on testing in plasma samples: stability limit for 29 biochemical analytes
CONCLUSIONS: A reduced stability of primary plasma samples was observed for five common biochemical analytes ordered in an emergency context. To ensure the quality of add-on testing for these samples, plasma aliquots provide stability for a longer period.PMID:38665870 | PMC:PMC11042558 | DOI:10.11613/BM.2024.020704 (Source: Biochemia Medica)
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Francisco J Illana Álvaro García-Osuna Mar ía Sospedra Rosa Ferrer Cec ília Martínez-Brú Leonor Gui ñón Source Type: research

Prediction interval: A powerful statistical tool for monitoring patients and analytical systems
Biochem Med (Zagreb). 2024 Jun 15;34(2):020101. doi: 10.11613/BM.2024.020101. Epub 2024 Apr 15.ABSTRACTMonitoring is indispensable for assessing disease prognosis and evaluating the effectiveness of treatment strategies, both of which rely on serial measurements of patients' data. It also plays a critical role in maintaining the stability of analytical systems, which is achieved through serial measurements of quality control samples. Accurate monitoring can be achieved through data collection, following a strict preanalytical and analytical protocol, and the application of a suitable statistical method. In a stable process...
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Abdurrahman Coskun Source Type: research

Hematological investigations in a case of intravascular hemolysis due to Clostridium perfringens infection
Biochem Med (Zagreb). 2024 Jun 15;34(2):021001. doi: 10.11613/BM.2024.021001. Epub 2024 Apr 15.ABSTRACTA patient presented with fever, severe pain and edematous tight due to hip trauma and was scheduled for urgent fasciotomy. Following physical examination, laboratory analyses were requested, and results revealed anemia and severe infection. As the patient's condition was serious, a new set of samples was sent to the laboratory four hours later. Following centrifugation, severely hemolyzed dark-colored serum and plasma samples were obtained and in vitro hemolysis was suspected. The collection of samples was repeated, but a...
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Anamarija Beljan Viktorija Blagec Ana Bronic Marina Pavi ć Source Type: research

Two cases with discrepancy in the quantitative cytological assessment of cerebrospinal fluid in neonatal samples using light microscopy in comparison with Sysmex XN-1000
We present two cases from the neonatal department with cerebrospinal fluid examination. We revealed a striking discrepancy in polymorphonuclear (PMN) and mononuclear (MN) cell counts using conventional light microscopy in comparison with automated analyzer Sysmex XN-1000 (PMNs - 13 vs. 173x106/L, MNs - 200 vs. 67x106/L in case 1 and PMNs - 13 vs. 372x106/L, MNs - 411 vs. 179x106/L in case 2). We revealed the dominant presence of hemosiderophages in both cases in cytospin slide. Even though Sysmex XN-1000 offers fast examination with a low sample volume, there is possibility of misdiagnosis, with negative impact on the pati...
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Pavel Broz Simona Kukralova Jana Palatova Klara Kolduskova Jana Zenkova Daniel Rajdl Jaroslav Racek Source Type: research

Comparison of lipemia interference created with native lipemic material and intravenous lipid emulsion in emergency laboratory tests
CONCLUSIONS: Significant differences were scrutinized in interference patterns of lipemia types, emphasizing the need for careful consideration of lipemia interferences in clinical laboratories. It is crucial to note that lipid emulsions inadequately replicate lipemic samples.PMID:38665874 | PMC:PMC11042557 | DOI:10.11613/BM.2024.020701 (Source: Biochemia Medica)
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Emel Çolak Samsum Hatice S ürer Serkan Bolat Mehmet Şeneş Do ğan Yücel Source Type: research

A survey on the practice of phlebotomy in Lithuania and adherence to the EFLM-COLABIOCLI recommendations: continuous training and clear standard operating procedures as tools for better quality
CONCLUSIONS: The findings of this study indicate that there is a significant need for improvement in compliance with the EFLM-COLABIOCLI recommendations on VBS among specialists in Lithuania. Essential measures include prioritizing ongoing phlebotomy training and establishing national guidelines. Harmonisation of blood collection practices across healthcare institutions is crucial.PMID:38665875 | PMC:PMC11042562 | DOI:10.11613/BM.2024.020702 (Source: Biochemia Medica)
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Ricardas Stonys Dalius Vitkus Source Type: research