Biotechnological potential of red yeast isolated from birch forests in Poland
CONCLUSION: Silver birch is a good natural source for the isolation of new strains of red yeast with wide biotechnological potential.PMID:38687405 | DOI:10.1007/s10529-024-03482-3 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 30, 2024 Category: Biotechnology Authors: Anna M Kot Paulina Laszek Marek Kieliszek Katarzyna Pobiega Stanis ław Błażejak Source Type: research
Biotechnological potential of red yeast isolated from birch forests in Poland
CONCLUSION: Silver birch is a good natural source for the isolation of new strains of red yeast with wide biotechnological potential.PMID:38687405 | DOI:10.1007/s10529-024-03482-3 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 30, 2024 Category: Biotechnology Authors: Anna M Kot Paulina Laszek Marek Kieliszek Katarzyna Pobiega Stanis ław Błażejak Source Type: research
Biotechnological potential of red yeast isolated from birch forests in Poland
CONCLUSION: Silver birch is a good natural source for the isolation of new strains of red yeast with wide biotechnological potential.PMID:38687405 | DOI:10.1007/s10529-024-03482-3 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 30, 2024 Category: Biotechnology Authors: Anna M Kot Paulina Laszek Marek Kieliszek Katarzyna Pobiega Stanis ław Błażejak Source Type: research
Facile engineering of aptamer-coupled silk fibroin encapsulated myogenic gold nanocomposites: investigation of antiproliferative activity and apoptosis induction
This study assessed the cytotoxicity of gold nanocomposites (Au NCs) enclosed within silk fibroin (SF), aptamer (Ap), and the myogenic Talaromyces purpureogenus (TP) against a human liver cancer cell (HepG2). The ultimate product, Ap-SF-TP@Au NCs, results from a three-step process. This process involves the myogenic synthesis of TP@Au NCs derived from TP mycelial extract, encapsulation of SF on TP@Au NCs (SF-TP@Au NCs), and the conjugation of Ap within SF-TP@Au NCs. The synthesized NCs are analyzed by various characteristic techniques. Ap-SF-TP@Au NCs induced potential cell death in HepG2 cells but exhibited no cytotoxicit...
Source: Biotechnology Letters - April 27, 2024 Category: Biotechnology Authors: Poorni Kaliyappan Elayappan Kavitha Kandasamy Vadivukkarasi Sasikumar Muruganantham Bharathi Abdurahman Hajinur Hirad Abdullah A Alarfaj Palanisamy Arulselvan Ravindran Jaganathan Rajeswari Ravindran Jagadeesh Suriyaprakash Indumathi Thangavelu Source Type: research
Facile engineering of aptamer-coupled silk fibroin encapsulated myogenic gold nanocomposites: investigation of antiproliferative activity and apoptosis induction
This study assessed the cytotoxicity of gold nanocomposites (Au NCs) enclosed within silk fibroin (SF), aptamer (Ap), and the myogenic Talaromyces purpureogenus (TP) against a human liver cancer cell (HepG2). The ultimate product, Ap-SF-TP@Au NCs, results from a three-step process. This process involves the myogenic synthesis of TP@Au NCs derived from TP mycelial extract, encapsulation of SF on TP@Au NCs (SF-TP@Au NCs), and the conjugation of Ap within SF-TP@Au NCs. The synthesized NCs are analyzed by various characteristic techniques. Ap-SF-TP@Au NCs induced potential cell death in HepG2 cells but exhibited no cytotoxicit...
Source: Biotechnology Letters - April 27, 2024 Category: Biotechnology Authors: Poorni Kaliyappan Elayappan Kavitha Kandasamy Vadivukkarasi Sasikumar Muruganantham Bharathi Abdurahman Hajinur Hirad Abdullah A Alarfaj Palanisamy Arulselvan Ravindran Jaganathan Rajeswari Ravindran Jagadeesh Suriyaprakash Indumathi Thangavelu Source Type: research
Facile engineering of aptamer-coupled silk fibroin encapsulated myogenic gold nanocomposites: investigation of antiproliferative activity and apoptosis induction
This study assessed the cytotoxicity of gold nanocomposites (Au NCs) enclosed within silk fibroin (SF), aptamer (Ap), and the myogenic Talaromyces purpureogenus (TP) against a human liver cancer cell (HepG2). The ultimate product, Ap-SF-TP@Au NCs, results from a three-step process. This process involves the myogenic synthesis of TP@Au NCs derived from TP mycelial extract, encapsulation of SF on TP@Au NCs (SF-TP@Au NCs), and the conjugation of Ap within SF-TP@Au NCs. The synthesized NCs are analyzed by various characteristic techniques. Ap-SF-TP@Au NCs induced potential cell death in HepG2 cells but exhibited no cytotoxicit...
Source: Biotechnology Letters - April 27, 2024 Category: Biotechnology Authors: Poorni Kaliyappan Elayappan Kavitha Kandasamy Vadivukkarasi Sasikumar Muruganantham Bharathi Abdurahman Hajinur Hirad Abdullah A Alarfaj Palanisamy Arulselvan Ravindran Jaganathan Rajeswari Ravindran Jagadeesh Suriyaprakash Indumathi Thangavelu Source Type: research
Novel small multidrug resistance protein Tmt endows the Escherichia coli with triphenylmethane dyes bioremediation capability
Biotechnol Lett. 2024 Apr 25. doi: 10.1007/s10529-024-03480-5. Online ahead of print.ABSTRACTDye contamination in printing and dyeing wastewater has long been a major concern due to its serious impact on both the environment and human health. In the quest for bioremediation of these hazardous dyes, biological resources such as biodegradation bacteria and enzymes have been investigated in severely polluted environments. In this context, the triphenylmethane transporter gene (tmt) was identified in six distinct clones from a metagenomic library of the printing and dyeing wastewater treatment system. Escherichia coli expressi...
Source: Biotechnology Letters - April 25, 2024 Category: Biotechnology Authors: Zhou Wang Haoqiang Zhou Yilan Cheng Lijin An Dazhong Yan Hongjun Chao Jing Wu Source Type: research
Novel small multidrug resistance protein Tmt endows the Escherichia coli with triphenylmethane dyes bioremediation capability
Biotechnol Lett. 2024 Apr 25. doi: 10.1007/s10529-024-03480-5. Online ahead of print.ABSTRACTDye contamination in printing and dyeing wastewater has long been a major concern due to its serious impact on both the environment and human health. In the quest for bioremediation of these hazardous dyes, biological resources such as biodegradation bacteria and enzymes have been investigated in severely polluted environments. In this context, the triphenylmethane transporter gene (tmt) was identified in six distinct clones from a metagenomic library of the printing and dyeing wastewater treatment system. Escherichia coli expressi...
Source: Biotechnology Letters - April 25, 2024 Category: Biotechnology Authors: Zhou Wang Haoqiang Zhou Yilan Cheng Lijin An Dazhong Yan Hongjun Chao Jing Wu Source Type: research
Novel small multidrug resistance protein Tmt endows the Escherichia coli with triphenylmethane dyes bioremediation capability
Biotechnol Lett. 2024 Apr 25. doi: 10.1007/s10529-024-03480-5. Online ahead of print.ABSTRACTDye contamination in printing and dyeing wastewater has long been a major concern due to its serious impact on both the environment and human health. In the quest for bioremediation of these hazardous dyes, biological resources such as biodegradation bacteria and enzymes have been investigated in severely polluted environments. In this context, the triphenylmethane transporter gene (tmt) was identified in six distinct clones from a metagenomic library of the printing and dyeing wastewater treatment system. Escherichia coli expressi...
Source: Biotechnology Letters - April 25, 2024 Category: Biotechnology Authors: Zhou Wang Haoqiang Zhou Yilan Cheng Lijin An Dazhong Yan Hongjun Chao Jing Wu Source Type: research
Neutralizing anti-diphtheria toxin scFv produced by phage display
CONCLUSION: This study describes the prosperous construction and isolation of scFv from the immune library, which specifically neutralizes diphtheria toxin. The HuscFv produced in this study can be a potential candidate to substitute the animal antibody for treating diphtheria and detecting toxins.PMID:38607601 | DOI:10.1007/s10529-024-03476-1 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Ehsan Khalili Mostafa Lakzaei Mahdi Aminian Source Type: research
Epigenetic modifiers as inducer of bioactive secondary metabolites in fungi
This study delves into the possibility of utilizing epigenetic modifying agents to generate pharmacologically significant secondary metabolites from fungi.PMID:38607602 | DOI:10.1007/s10529-024-03478-z (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Vishal Sharma Shivali Panjgotra Nisha Sharma Vidushi Abrol Umesh Goutam Sundeep Jaglan Source Type: research
Pilot-scale production of Bacillus subtilis MSCL 897 spore biomass and antifungal secondary metabolites in a low-cost medium
CONCLUSION: An economically-feasible process for B. subtilis-based biocontrol agent production was successfully developed at the pilot scale.PMID:38607603 | DOI:10.1007/s10529-024-03481-4 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Emils Bolmanis Oskars Grigs Elina Didrihsone Maris Senkovs Vizma Nikolajeva Source Type: research
A cellulosomal yeast reaction system of lignin-degrading enzymes for cellulosic ethanol fermentation
In this study, a composite functional chimeric cellulosome equipped with laccase, versatile peroxidase, and lytic polysaccharide monooxygenase was riveted on the surface of Saccharomyces cerevisiae to construct a novel yeast strain YI/LVP for synergistic lignin degradation and cellulosic ethanol production. The assembly of cellulosome was assayed by immunofluorescence microscopy and flow cytometry. During the whole process of fermentation, the maximum ethanol concentration and cellulose conversion of engineering strain YI/LVP reached 8.68 g/L and 83.41%, respectively. The results proved the availability of artificial chime...
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Yutong Ye Han Liu Zhipeng Wang Qi Qi Jiliang Du Shen Tian Source Type: research
Neutralizing anti-diphtheria toxin scFv produced by phage display
CONCLUSION: This study describes the prosperous construction and isolation of scFv from the immune library, which specifically neutralizes diphtheria toxin. The HuscFv produced in this study can be a potential candidate to substitute the animal antibody for treating diphtheria and detecting toxins.PMID:38607601 | DOI:10.1007/s10529-024-03476-1 (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Ehsan Khalili Mostafa Lakzaei Mahdi Aminian Source Type: research
Epigenetic modifiers as inducer of bioactive secondary metabolites in fungi
This study delves into the possibility of utilizing epigenetic modifying agents to generate pharmacologically significant secondary metabolites from fungi.PMID:38607602 | DOI:10.1007/s10529-024-03478-z (Source: Biotechnology Letters)
Source: Biotechnology Letters - April 12, 2024 Category: Biotechnology Authors: Vishal Sharma Shivali Panjgotra Nisha Sharma Vidushi Abrol Umesh Goutam Sundeep Jaglan Source Type: research
