3D printing of Ceffe-infused scaffolds for tailored nipple-like cartilage development
The reconstruction of a stable, nipple-shaped cartilage graft that precisely matches the natural nipple in shape and size on the contralateral side is a clinical challenge. While 3D printing technology can eff... (Source: BMC Biotechnology)
Source: BMC Biotechnology - April 30, 2024 Category: Biotechnology Authors: Jinghao Ding, Chuanzhi Wei, Yong Xu, Wufei Dai and Ru Chen Tags: Research Source Type: research
A cleavable peptide adapter augments the activity of targeted toxins in combination with the glycosidic endosomal escape enhancer SO1861
Treatment with tumor-targeted toxins attempts to overcome the disadvantages of conventional cancer therapies by directing a drug ’s cytotoxic effect specifically towards cancer cells. However, success with targ... (Source: BMC Biotechnology)
Source: BMC Biotechnology - April 29, 2024 Category: Biotechnology Authors: Finn J. Schulze, Mazdak Asadian-Birjand, Michael Pradela, Nicole Niesler, Gregor Nagel and Hendrik Fuchs Tags: Research Source Type: research
Multiprotein collagen/keratin hydrogel promoted myogenesis and angiogenesis of injured skeletal muscles in a mouse model
Volumetric loss is one of the challenging issues in muscle tissue structure that causes functio laesa. Tissue engineering of muscle tissue using suitable hydrogels is an alternative to restoring the physiological... (Source: BMC Biotechnology)
Source: BMC Biotechnology - April 26, 2024 Category: Biotechnology Authors: Atieh Rezaei Namjoo, Ayla Hassani, Hassan Amini, Fateme Nazaryabrbekoh, Sepideh Saghati, Mohammad Ali Ebrahimi Saadatlou, Ali Baradar Khoshfetrat, Nafiseh Didar Khosrowshahi and Reza Rahbarghazi Tags: Research Source Type: research
Analysis of the impact of pluronic acid on the thermal stability and infectivity of AAV6.2FF
The advancement of AAV vectors into clinical testing has accelerated rapidly over the past two decades. While many of the AAV vectors being utilized in clinical trials are derived from natural serotypes, engin... (Source: BMC Biotechnology)
Source: BMC Biotechnology - April 25, 2024 Category: Biotechnology Authors: Sylvia P. Thomas, Marcus M. Spinelli, Amira D. Rghei, Jordyn A. Lopes, Nicole Zielinska, Benjamin M. McLeod, Yanlong Pei, Wei Zhang, Bernard Thebaud, Khalil Karimi and Sarah K. Wootton Tags: Research Source Type: research
Rice yellow mottle virus is a suitable amplicon vector for an efficient production of an anti-leishmianiasis vaccine in Nicotiana benthamiana leaves
Since the 2000 ’s, plants have been used as bioreactors for the transient production of molecules of interest such as vaccines. To improve protein yield, “amplicon” vectors based on plant viruses are used. Thes... (Source: BMC Biotechnology)
Source: BMC Biotechnology - April 24, 2024 Category: Biotechnology Authors: PKA Bamogo, F Tiendr ébéogo, C Brugidou, D Sérémé, FW Djigma, J Simporé and S Lacombe Tags: Research Source Type: research
Extraction and analysis of high-quality chloroplast DNA with reduced nuclear DNA for medicinal plants
Obtaining high-quality chloroplast genome sequences requires chloroplast DNA (cpDNA) samples that meet the sequencing requirements. The quality of extracted cpDNA directly impacts the efficiency and accuracy o... (Source: BMC Biotechnology)
Source: BMC Biotechnology - April 18, 2024 Category: Biotechnology Authors: Yifan Yu, Xinxin Wang, Renjun Qu, Zhen OuYang, Juan Guo, Yujun Zhao and Luqi Huang Tags: Research Source Type: research
Transcriptomic and targeted metabolomic analyses provide insights into the flavonoids biosynthesis in the flowers of Lonicera macranthoides
In this study, combined transcriptomic and targeted metabo... (Source: BMC Biotechnology)
Source: BMC Biotechnology - April 12, 2024 Category: Biotechnology Authors: Ling Ling Lv, Li Yun Li, Long Qian Xiao and Jian Hui Pi Tags: Research Source Type: research
Effects of solid lipid nanocarrier containing methyl urolithin A by coating folate-bound chitosan and evaluation of its anti-cancer activity
Nanotechnology-based drug delivery systems have received much attention over the past decade. In the present study, we synthesized Methyl Urolithin A-loaded solid lipid nanoparticles decorated with the folic a... (Source: BMC Biotechnology)
Source: BMC Biotechnology - April 10, 2024 Category: Biotechnology Authors: Ilham Naeem Abd Ali Al-Fatlawi, Vahid Pouresmaeil, Fatemeh Davoodi-Dehaghani, Aida Pouresmaeil, Ali Akhtari and Masoud Homayouni Tabrizi Tags: Research Source Type: research
Neq2X7: a multi-purpose and open-source fusion DNA polymerase for advanced DNA engineering and diagnostics PCR
Thermostable DNA polymerases, such as Taq isolated from the thermophilic bacterium Thermus aquaticus, enable one-pot exponential DNA amplification known as polymerase chain reaction (PCR). However, properties oth... (Source: BMC Biotechnology)
Source: BMC Biotechnology - April 2, 2024 Category: Biotechnology Authors: Cristina Hern ández-Rollán, Anja K. Ehrmann, Arsenios Vlassis, Vijayalakshmi Kandasamy and Morten H. H. Nørholm Tags: Research Source Type: research
A solution for highly efficient electroporation of primary cytotoxic T lymphocytes
Cytotoxic T lymphocytes (CTLs) are central players in the adaptive immune response. Their functional characterization and clinical research depend on efficient and reliable transfection. Although various metho... (Source: BMC Biotechnology)
Source: BMC Biotechnology - March 26, 2024 Category: Biotechnology Authors: Nadia Alawar, Claudia Schirra, Meltem Hohmann and Ute Becherer Tags: Research Source Type: research
Adsorption of Hg2+/Cr6+ by metal-binding proteins heterologously expressed in Escherichia coli
In this study, the m... (Source: BMC Biotechnology)
Source: BMC Biotechnology - March 23, 2024 Category: Biotechnology Authors: Shuting Hu, Zixiang Wei, Teng Liu, Xinyu Zuo and Xiaoqiang Jia Tags: Research Source Type: research
Derivation of a novel antimicrobial peptide from the Red Sea Brine Pools modified to enhance its anticancer activity against U2OS cells
Cancer associated drug resistance is a major cause for cancer aggravation, particularly as conventional therapies have presented limited efficiency, low specificity, resulting in long term deleterious side eff... (Source: BMC Biotechnology)
Source: BMC Biotechnology - March 15, 2024 Category: Biotechnology Authors: Mona Elradi, Ahmed I. Ahmed, Ahmed M. Saleh, Khaled M. A. Abdel-Raouf, Lina Berika, Yara Daoud and Asma Amleh Tags: Research Source Type: research
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice
This study plan to explore the mechanism of Polyphyllin B in lung injury induced by cigarette smoke (CSE) in COPD. (Source: BMC Biotechnology)
Source: BMC Biotechnology - March 8, 2024 Category: Biotechnology Authors: Qing Wang, Zhiyi He, Jinqi Zhu, Mengyun Hu, Liu Yang and Hongzhong Yang Tags: Research Source Type: research
Quantifying carboxymethyl lysine and carboxyethyl lysine in human plasma: clinical insights into aging research using liquid chromatography-tandem mass spectrometry
The objective of this study was to establish a methodology for determining carboxymethyl lysine (CML) and carboxyethyl lysine (CEL) concentrations in human plasma using liquid chromatography-tandem mass spectr... (Source: BMC Biotechnology)
Source: BMC Biotechnology - March 7, 2024 Category: Biotechnology Authors: Daguang Wang, Junshan Wang, Xinghong Liu, Kehe Du, Hongjun Liu, Xiaofeng Yang, Tianyi Liu, Qian Liu, Meng Wang and Jian Guo Tags: Research Source Type: research
Iron/Copper/Phosphate nanocomposite as antimicrobial, antisnail, and wheat growth-promoting agent
One of the current challenges is to secure wheat crop production to meet the increasing global food demand and to face the increase in its purchasing power. Therefore, the current study aimed to exploit a new ... (Source: BMC Biotechnology)
Source: BMC Biotechnology - March 5, 2024 Category: Biotechnology Authors: Nashwa H. Abdullah, Nouran A. Elbialy, Mohamed Abdelnaser Amer, Mostafa Kh. Gabr, Amira Salah El-Din Youssef, Mohamed H. Sharaf, M. E. Shehata, Mohamed H. Kalaba and Elham R. S. Soliman Tags: Research Source Type: research
