Genome-wide prediction and functional analysis of WOX genes in blueberry
WOX genes are a class of plant-specific transcription factors. The WUSCHEL-related homeobox (WOX) family is a member of the homeobox transcription factor superfamily. Previous studies have shown that WOX members ... (Source: BMC Genomics)
Source: BMC Genomics - May 2, 2024 Category: Genetics & Stem Cells Authors: Yanwen Wang, Lei Yang, Wenzhu Geng, Rui Cheng, Hongxia Zhang and Houjun Zhou Tags: Research Source Type: research

Dynamic evolution of the mTHF gene family associated with primary metabolism across life
The folate cycle of one-carbon (C1) metabolism, which plays a central role in the biosynthesis of nucleotides and amino acids, demonstrates the significance of metabolic adaptation. We investigated the evoluti... (Source: BMC Genomics)
Source: BMC Genomics - May 1, 2024 Category: Genetics & Stem Cells Authors: Adam M. Rork, Arthi S. Bala and Tanya Renner Tags: Research Source Type: research

DengueSeq: a pan-serotype whole genome amplicon sequencing protocol for dengue virus
The increasing burden of dengue virus on public health due to more explosive and frequent outbreaks highlights the need for improved surveillance and control. Genomic surveillance of dengue virus not only prov... (Source: BMC Genomics)
Source: BMC Genomics - May 1, 2024 Category: Genetics & Stem Cells Authors: Chantal B. F. Vogels, Verity Hill, Mallery I. Breban, Chrispin Chaguza, Lauren M. Paul, Afeez Sodeinde, Emma Taylor-Salmon, Isabel M. Ott, Mary E. Petrone, Dennis Dijk, Marcel Jonges, Matthijs R. A. Welkers, Timothy Locksmith, Yibo Dong, Namratha Tarigopu Tags: Research Source Type: research

Annotations of four high-quality indigenous chicken genomes identify more than one thousand missing genes in subtelomeric regions and micro-chromosomes with high G/C contents
Although multiple chicken genomes have been assembled and annotated, the numbers of protein-coding genes in chicken genomes and their variation among breeds are still uncertain due to the low quality of these ... (Source: BMC Genomics)
Source: BMC Genomics - May 1, 2024 Category: Genetics & Stem Cells Authors: Siwen Wu, Tengfei Dou, Sisi Yuan, Shixiong Yan, Zhiqiang Xu, Yong Liu, Zonghui Jian, Jingying Zhao, Rouhan Zhao, Xiannian Zi, Dahai Gu, Lixian Liu, Qihua Li, Dong-Dong Wu, Junjing Jia, Changrong Ge & hellip; Tags: Research Source Type: research

Ocular A-to-I RNA editing signatures associated with SARS-CoV-2 infection
Ophthalmic manifestations have recently been observed in acute and post-acute complications of COVID-19 caused by SARS-CoV-2 infection. Our precious study has shown that host RNA editing is linked to RNA viral... (Source: BMC Genomics)
Source: BMC Genomics - May 1, 2024 Category: Genetics & Stem Cells Authors: Yun-Yun Jin, Ya-Ping Liang, Wen-Hao Huang, Liang Guo, Li-Li Cheng, Tian-Tian Ran, Jin-Ping Yao, Lin Zhu and Jian-Huan Chen Tags: Research Source Type: research

Artificial selection footprints in indigenous and commercial chicken genomes
Although many studies have been done to reveal artificial selection signatures in commercial and indigenous chickens, a limited number of genes have been linked to specific traits. To identify more trait-relat... (Source: BMC Genomics)
Source: BMC Genomics - April 30, 2024 Category: Genetics & Stem Cells Authors: Siwen Wu, Tengfei Dou, Kun Wang, Sisi Yuan, Shixiong Yan, Zhiqiang Xu, Yong Liu, Zonghui Jian, Jingying Zhao, Rouhan Zhao, Hao Wu, Dahai Gu, Lixian Liu, Qihua Li, Dong-Dong Wu, Changrong Ge & hellip; Tags: Research Source Type: research

Cis-eQTLs in seven duck tissues identify novel candidate genes for growth and carcass traits
Expression quantitative trait loci (eQTL) studies aim to understand the influence of genetic variants on gene expression. The colocalization of eQTL mapping and GWAS strategy could help identify essential cand... (Source: BMC Genomics)
Source: BMC Genomics - April 30, 2024 Category: Genetics & Stem Cells Authors: Wentao Cai, Jian Hu, Yunsheng Zhang, Zhanbao Guo, Zhengkui Zhou and Shuisheng Hou Tags: Research Source Type: research

NKX2-2 based nuclei sorting on frozen human archival pancreas enables the enrichment of islet endocrine populations for single-nucleus RNA sequencing
Current approaches to profile the single-cell transcriptomics of human pancreatic endocrine cells almost exclusively rely on freshly isolated islets. However, human islets are limited in availability. Furtherm... (Source: BMC Genomics)
Source: BMC Genomics - April 30, 2024 Category: Genetics & Stem Cells Authors: Gengqiang Xie, Maria Pilar Toledo, Xue Hu, Hyo Jeong Yong, Pamela Sandoval Sanchez, Chengyang Liu, Ali Naji, Jerome Irianto and Yue J. Wang Tags: Research Source Type: research

Elucidating the multichromosomal structure within the Brasenia schreberi mitochondrial genome through assembly and analysis
Brasenia schreberi, a plant species traditionally utilized in Chinese medicine and cuisine, represents an early evolutionary stage among flowering plants (angiosperms). While the plastid genome of this species ha... (Source: BMC Genomics)
Source: BMC Genomics - April 29, 2024 Category: Genetics & Stem Cells Authors: Yuanyu Shan, Jingling Li, Xinmei Duan, Xue Zhang and Jie Yu Tags: Research Source Type: research

scCompressSA: dual-channel self-attention based deep autoencoder model for single-cell clustering by compressing gene –gene interactions
Single-cell clustering has played an important role in exploring the molecular mechanisms about cell differentiation and human diseases. Due to highly-stochastic transcriptomics data, accurate detection of cel... (Source: BMC Genomics)
Source: BMC Genomics - April 29, 2024 Category: Genetics & Stem Cells Authors: Wei Zhang, Ruochen Yu, Zeqi Xu, Junnan Li, Wenhao Gao, Mingfeng Jiang and Qi Dai Tags: Research Source Type: research

Machine learning assists prediction of genes responsible for plant specialized metabolite biosynthesis by integrating multi-omics data
Plant specialized (or secondary) metabolites (PSM), also known as phytochemicals, natural products, or plant constituents, play essential roles in interactions between plants and environment. Although many res... (Source: BMC Genomics)
Source: BMC Genomics - April 29, 2024 Category: Genetics & Stem Cells Authors: Wenhui Bai, Cheng Li, Wei Li, Hai Wang, Xiaohong Han, Peipei Wang and Li Wang Tags: Research Source Type: research

Phylogenomic analyses and reclassification of the Mesorhizobium complex: proposal for 9 novel genera and reclassification of 15 species
The genus Mesorhizobium is shown by phylogenomics to be paraphyletic and forms part of a complex that includes the genera Aminobacter, Aquamicrobium, Pseudaminobacter and Tianweitania. The relationships for type ... (Source: BMC Genomics)
Source: BMC Genomics - April 29, 2024 Category: Genetics & Stem Cells Authors: Yan Li, Tingyan Guo, Liqin Sun, En-Tao Wang, J. Peter W. Young and Chang-Fu Tian Tags: Research Source Type: research

Selection signatures and landscape genomics analysis to reveal climate adaptation of goat breeds
Goats have achieved global prominence as essential livestock since their initial domestication, primarily owing to their remarkable adaptability to diverse environmental and production systems. Differential se... (Source: BMC Genomics)
Source: BMC Genomics - April 29, 2024 Category: Genetics & Stem Cells Authors: Weifeng Peng, Yiyuan Zhang, Lei Gao, Wanlu Shi, Zi Liu, Xinyu Guo, Yunxia Zhang, Bing Li, Guoyin Li, Jingya Cao and Mingsheng Yang Tags: Research Source Type: research

Using Portuguese BRCA pathogenic variation as a model to study the impact of human admixture on human health
Admixture occurs between different ethnic human populations. The global colonization in recent centuries by Europeans led to the most significant admixture in human history. While admixture may enhance genetic... (Source: BMC Genomics)
Source: BMC Genomics - April 27, 2024 Category: Genetics & Stem Cells Authors: Stephanie Andaluz, Bojin Zhao, Siddharth Sinha, Philip Naderev Panuringan Lagniton, Diogo Alpuim Costa, Xiaofan Ding, Miguel Brito and San Ming Wang Tags: Research Source Type: research

An autosomal recessive variant in PYGM causes myophosphorylase deficiency in Red Angus composite cattle
Between 2020 and 2022, eight calves in a Nebraska herd (composite Simmental, Red Angus, Gelbvieh) displayed exercise intolerance during forced activity. In some cases, the calves collapsed and did not recover.... (Source: BMC Genomics)
Source: BMC Genomics - April 27, 2024 Category: Genetics & Stem Cells Authors: Mackenzie C. Batt, Leila G. Venzor, Keri Gardner, Rachel R. Reith, Kelsey A. Roberts, Nicolas J. Herrera, Anna M. Fuller, Gary A. Sullivan, J. Travis Mulliniks, Matthew L. Spangler, Stephanie J. Valberg, David J. Steffen and Jessica L. Petersen Tags: Research Source Type: research