Atypical memory B cells increase in the peripheral blood of patients with breast cancer regardless of lymph node involvement
Breast cancer is the most common cancer in females. The immune system has a crucial role in the fight against cancer. B and T cells, the two main components of the adaptive immunity, are critical players that ... (Source: BMC Immunology)
Source: BMC Immunology - May 3, 2024 Category: Allergy & Immunology Authors: Atefeh Azizi, Fereshteh Mehdipour, Morteza Samadi, Reza Rasolmali, Abdol-Rasoul Talei and Abbas Ghaderi Tags: Research Source Type: research

The role of the immune system in early-onset schizophrenia: identifying immune characteristic genes and cells from peripheral blood
Early-onset schizophrenia (EOS) is a type of schizophrenia (SCZ) with an age of onset of   (Source: BMC Immunology)
Source: BMC Immunology - May 3, 2024 Category: Allergy & Immunology Authors: Zi Chen, Yuxue Li, Yao Gao, Xiaoxuan Fan, Xinzhe Du, Xinrong Li, Zhifen Liu, Sha Liu and Xiaohua Cao Tags: Research Source Type: research

The influence of neonatal BCG vaccination on in vitro cytokine responses to Plasmodium falciparum
Bacillus Calmette –Guérin (BCG) vaccination has off-target protective effects against infections unrelated to tuberculosis. Among these, murine and human studies suggest that BCG vaccination may protect against... (Source: BMC Immunology)
Source: BMC Immunology - April 30, 2024 Category: Allergy & Immunology Authors: NL Messina, M Wang, EK Forbes, B Freyne, WP Hasang, S Germano, R Bonnici, F Summons, K Gardiner, S Donath, R Gordon, SJ Rogerson and N Curtis Tags: Research Source Type: research

Basophil activation in insect venom allergy: comparison of an established test using liquid reagents with a test using 5-color tubes with dried antibody reagents
Flow cytometry-based basophil activation tests (BAT) have been performed with various modifications, differing in the use of distinct identification and activation markers. Established tests use liquid reagent... (Source: BMC Immunology)
Source: BMC Immunology - April 27, 2024 Category: Allergy & Immunology Authors: Sebastian Waldherr, Miriam Hils, Martin K öberle, Knut Brockow, Ulf Darsow, Simon Blank, Tilo Biedermann and Bernadette Eberlein Tags: Research Source Type: research

Advanced in immunological monitoring of HIV infection: profile of immune cells and cytokines in people living with HIV-1 in Benin
Immune cells and cytokines have been linked to viremia dynamic and immune status during HIV infection. They may serve as useful biomarkers in the monitoring of people living with HIV-1 (PLHIV-1). The present w... (Source: BMC Immunology)
Source: BMC Immunology - April 20, 2024 Category: Allergy & Immunology Authors: Yaou Pierrot Assogba, Adefounke Prudencia Adechina, Edmond Tchiakpe, Odilon Paterne Nouatin, Ren é K. Kèkè, Moussa Bachabi, Honoré Sourou Bankole and Akadiri Yessoufou Tags: Research Source Type: research

Helminth-derived proteins as immune system regulators: a systematic review of their promise in alleviating colitis
Helminth-derived proteins have immunomodulatory properties, influencing the host ’s immune response as an adaptive strategy for helminth survival. Helminth-derived proteins modulate the immune response by induc... (Source: BMC Immunology)
Source: BMC Immunology - April 18, 2024 Category: Allergy & Immunology Authors: Maimonah Alghanmi, Faisal Minshawi, Tarfa A. Altorki, Ayat Zawawi, Isra Alsaady, Abdallah Y Naser, Hassan Alwafi, Soa ’ad M. Alsulami, Ala A. Azhari, Anwar M Hashem and Rowa Alhabbab Tags: Research Source Type: research

Association of interleukin-17A and chemokine/vascular endothelial growth factor-induced angiogenesis in newly diagnosed patients with bladder cancer
The human interleukin-17 (IL-17) family comprises IL-17A to IL-17 F; their receptors are IL-17RA to IL-17RE. Evidence revealed that these cytokines can have a tumor-supportive or anti-tumor impact on human mal... (Source: BMC Immunology)
Source: BMC Immunology - March 21, 2024 Category: Allergy & Immunology Authors: Ali Moadab, Mohammad Rafie Valizadeh, Alireza Nazari and Hossein Khorramdelazad Tags: Research Source Type: research

Causal relationship between immune cells and telomere length: mendelian randomization analysis
The causal relationship between immune cells and telomere length remains controversial. (Source: BMC Immunology)
Source: BMC Immunology - March 8, 2024 Category: Allergy & Immunology Authors: Yujian Li, Shenglin Lai and Xuan Kan Tags: Research Source Type: research

Subcutaneous immunoglobulin replacement therapy in patients with immunodeficiencies – impact of drug packaging and administration method on patient reported outcomes
Here, the perspective of patients with primary and secondary immunodeficiency receiving subcutaneous immunoglobulin (SCIg) via introductory smaller size pre-filled syringes (PFS) or vials were compared. (Source: BMC Immunology)
Source: BMC Immunology - February 20, 2024 Category: Allergy & Immunology Authors: R. Mallick, G. Solomon, P. Bassett, X. Zhang, P. Patel and O. Lepeshkina Tags: Research Source Type: research

Network pharmacology-based strategy to investigate the mechanisms of artemisinin in treating primary Sj ögren’s syndrome
The study aimed to explore the mechanism of artemisinin in treating primary Sj ögren’s syndrome (pSS) based on network pharmacology and experimental validation. (Source: BMC Immunology)
Source: BMC Immunology - February 12, 2024 Category: Allergy & Immunology Authors: Jia-he Liao, Qian He, Zi-wei Huang, Xin-bo Yu, Jian-ying Yang, Yan Zhang, Wei-jiang Song, Jing Luo and Qing-wen Tao Tags: Research Source Type: research

Dendritic cells under allergic condition enhance the activation of pruritogen-responsive neurons via inducing itch receptors in a co-culture study
Itch sensitization has been reported in patients with chronic allergic skin diseases and observed in a mouse model of allergic contact dermatitis (ACD). There is evidence suggesting that neuroimmune interactio... (Source: BMC Immunology)
Source: BMC Immunology - February 12, 2024 Category: Allergy & Immunology Authors: Tichakorn Singto, Viviane Filor, Jonathan Vidak, Robert Klopfleisch and Wolfgang B äumer Tags: Research Source Type: research

Immune responses to P falciparum antibodies in symptomatic malaria patients with variant hemoglobin genotypes in Ghana
Haemoglobin (Hb) variants such as sickle cell trait (SCT/HbAS) play a role in protecting against clinical malaria, but little is known about the development of immune responses against malaria parasite (Plasmodiu... (Source: BMC Immunology)
Source: BMC Immunology - February 9, 2024 Category: Allergy & Immunology Authors: Kwame Kumi Asare, Benjamin Agrah, Fiifi Solomon Ofori-Acquah, William Kudzi, Nii Ayite Aryee and Linda Eva Amoah Tags: Research Source Type: research

Hyperactivation and enhanced cytotoxicity of reduced CD8+ gamma delta T cells in the intestine of patients with Crohn ’s disease correlates with disease activity
We aimed to investigate the immune characteristics of intestinal CD8+ gamma delta T (CD8+ γδ T) cells in Crohn’s disease (CD) and their correlation with disease activity. (Source: BMC Immunology)
Source: BMC Immunology - February 9, 2024 Category: Allergy & Immunology Authors: Tao Zhu, Linlin Zhu, Caixia Sheng, Danju Wu, Qianru Gu, Zhinong Jiang, Jiaqi Xu, Guoxiang Fu and Yujie Jiang Tags: Research Source Type: research

Systematic evaluation of B-cell clonal family inference approaches
The reconstruction of clonal families (CFs) in B-cell receptor (BCR) repertoire analysis is a crucial step to understand the adaptive immune system and how it responds to antigens. The BCR repertoire of an ind... (Source: BMC Immunology)
Source: BMC Immunology - February 8, 2024 Category: Allergy & Immunology Authors: Daria Balashova, Barbera D. C. van Schaik, Maria Stratigopoulou, Jeroen E. J. Guikema, Tom G. Caniels, Mathieu Claireaux, Marit J. van Gils, Anne Musters, Dornatien C. Anang, Niek de Vries, Victor Greiff and Antoine H. C. van Kampen Tags: Research Source Type: research

Expression of the immune checkpoint molecules CD226 and TIGIT in preeclampsia patients
Imbalanced immune responses are involved in developing preeclampsia (PE). We wish to explore the expression and potential changes of immune checkpoint molecules TIGIT, CD226 and CD155 in PE patients. (Source: BMC Immunology)
Source: BMC Immunology - February 7, 2024 Category: Allergy & Immunology Authors: Cui Li, Haiyan Liu and Zhongliang Duan Tags: Research Source Type: research