Peripheral blood biomarkers associated with combination of immune checkpoint blockade plus chemotherapy in NSCLC
CONCLUSIONS: We conclude that NK cells, CD4 + PD-1 + Tim-3 + T cells, and CXCL10 levels in pre-treatment peripheral blood may predict the efficacy of combination of ICI/chemotherapy in NSCLC.PMID:38669521 | DOI:10.3233/CBM-230301 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - April 26, 2024 Category: Cancer & Oncology Authors: Nozomu Kimura Yoko Tsukita Risa Ebina-Shibuya Eisaku Miyauchi Mitsuhiro Yamada Daisuke Narita Ryota Saito Chihiro Inoue Naoya Fujino Tomohiro Ichikawa Tsutomu Tamada Hisatoshi Sugiura Source Type: research

PRDM1 rs2185379, unlike BRCA1, is not a prognostic marker in patients with advanced ovarian cancer
CONCLUSIONS: Unlike age at diagnosis, OC histology or gBRCA1 status, rs2185379 in PRDM1 is unlikely a marker of long-term survival in patients with advance OC.PMID:38607753 | DOI:10.3233/CBM-230358 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - April 12, 2024 Category: Cancer & Oncology Authors: Klara Horackova Michal Vocka Sarka Lopatova Petra Zemankova Zdenek Kleibl Jana Soukupova Source Type: research

Circ_0049271 targets the miR-1197/PTRF axis to attenuate the malignancy of osteosarcoma
CONCLUSIONS: Our findings revealed that circ_0049271 targeted the miR-1197/PTRF axis to attenuate the malignancy of OS, suggesting a potential target for its clinical treatment.PMID:38578882 | DOI:10.3233/CBM-230191 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - April 5, 2024 Category: Cancer & Oncology Authors: Yixin Wen Feng Xu Hui Zhang Source Type: research