Transition-Metal-Based Nanozymes: Synthesis, Mechanisms of Therapeutic Action, and Applications in Cancer Treatment
ACS Nano. 2024 May 1. doi: 10.1021/acsnano.4c02265. Online ahead of print.ABSTRACTCancer, as one of the leading causes of death worldwide, drives the advancement of cutting-edge technologies for cancer treatment. Transition-metal-based nanozymes emerge as promising therapeutic nanodrugs that provide a reference for cancer therapy. In this review, we present recent breakthrough nanozymes for cancer treatment. First, we comprehensively outline the preparation strategies involved in creating transition-metal-based nanozymes, including hydrothermal method, solvothermal method, chemical reduction method, biomimetic mineralizati...
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Qinrui Fu Chuang Wei Mengzhen Wang Source Type: research

Positional obstructive sleep apnea and periodic limb movement during sleep: A large multi-center study
CONCLUSION: The POSA group tended to have a higher prevalence of PLMS, particularly in those with severe OSA. If PLMS is prominent, diagnosis and treatment of POSA and OSA may be considered.PMID:38693650 | DOI:10.21053/ceo.2024.00034 (Source: Cancer Control)
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Jae Hyun Soh Yun Jin Kang Won-Hyuck Yoon Chan-Soon Park Hyun-Woo Shin Source Type: research

Analysis of the epidemiological situation of influenza in Guangzhou under the prevention and control of COVID-19 in June 2022
CONCLUSION: A high proportion of adolescents and adults has respiratory pathogens detected during fever illnesses during June in 2022 under the prevention and control of COVID-19. These data indicate that diagnosis, prevention, and control of respiratory tract infection should be paid attention under the prevention and control of COVID-19.PMID:38693702 | DOI:10.1111/crj.13754 (Source: Cancer Control)
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Yuezhi Deng Yongping Lin Weihong Lin Source Type: research

Localization of Intramuscular mRNA Delivery using Deep Eutectic-Lipid Nanocomposites
This article is protected by copyright. All rights reserved.PMID:38693774 | DOI:10.1002/adhm.202400327 (Source: Cancer Control)
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: A M Curreri M Dunne G Bibbey N Kapate J Kim S Mitragotri Source Type: research

Early-pregnancy sex steroid and thyroid function hormones, thyroid autoimmunity, and maternal papillary thyroid cancer incidence in the Finnish Maternity Cohort
Int J Cancer. 2024 May 2. doi: 10.1002/ijc.34974. Online ahead of print.ABSTRACTThyroid cancer more commonly affects women than men and is the third most frequently diagnosed cancer among women of reproductive age. We conducted a nested case-control study within the Finnish Maternity Cohort to evaluate pre-diagnostic sex steroid and thyroid function markers in relation to subsequent maternal papillary thyroid cancer. Cases (n = 605) were women ages 18-44 years, who provided an early-pregnancy (<20 weeks gestation) blood sample and were diagnosed with papillary thyroid cancer up to 11 years afterward. Controls (n = 1185)...
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Cari M Kitahara Helj ä-Marja Surcel Roni Falk Ruth M Pfeiffer Tuija M ännistö Mika Gissler Britton Trabert Source Type: research

Laser Interstitial Thermotherapy (LITT) in Recurrent Glioblastoma: What Window of Opportunity for This Treatment?
We describe the most recent updates regarding several studies and case reports that have evaluated the efficacy and safety of Laser Interstitial Thermotherapy for recurrent gliomas. These studies have reported different outcomes, with some demonstrating promising results in terms of tumor control and patient survival, while others have shown mixed outcomes. The success of Laser Interstitial Thermotherapy depends on various factors, including tumor characteristics, patient selection, and the experience of the surgical team, but the future direction of treatment of recurrent gliomas will include a combined approach, comprisi...
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Alberto Morello Andrea Bianconi Francesca Rizzo Jacopo Bellomo Anna Cristina Meyer Diego Garbossa Luca Regli Fabio Cofano Source Type: research

New synergistic combination therapy approaches with HDAC inhibitor quisinostat, cisplatin or PARP inhibitor talazoparib for urothelial carcinoma
In conclusion, our results suggest new promising combination regimes for treatment of UC, also in the cisplatin-resistant setting.PMID:38693852 | DOI:10.1111/jcmm.18342 (Source: Cancer Control)
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Sarah Meneceur Caroline E De Vos Patrick Petzsch Karl K öhrer G ünter Niegisch Mich èle J Hoffmann Source Type: research

Economic Considerations for Implementing Tobacco Cessation Programs in Cancer Care Settings
Cancer Prev Res (Phila). 2024 May 2;17(5):197-199. doi: 10.1158/1940-6207.CAPR-24-0122.ABSTRACTIncreasingly, research demonstrates economic benefits of tobacco cessation in cancer care, as seen in a new study by Kypriotakis and colleagues of the MD Anderson cessation program, demonstrating median health care cost savings of $1,095 per patient over 3 months. While the cost-effectiveness of tobacco cessation programs from a hospital perspective is important, implementation decisions in a predominantly fee-for-service system, such as in the United States, too often insufficiently value this outcome. Economic barriers, stakeho...
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Ramzi G Salloum Kimberly A Shoenbill Adam O Goldstein Source Type: research

Evaluation of the effects of postoperative pleural empyema on survival rates of patients after pneumonectomy due to non-small cell lung cancer
CONCLUSIONS: Pleural empyema in NSCLC patients who underwent pneumonectomy seems to improve the survival outcomes compared to patients with uneventful recoveries.PMID:38693979 | PMC:PMC11059016 | DOI:10.5114/kitp.2024.138376 (Source: Cancer Control)
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Janusz W ójcik Tomasz Grodzki Krzysztof Safranow Jaros ław Pieróg Ma łgorzata Edyta Wojtyś Dawid Kordykiewicz Norbert W ójcik Source Type: research

The effects of resistance exercise and leucine-enriched essential amino acid supplementation on muscle mass and physical function in post-gastrectomy patients: a pilot randomized controlled trial
Conclusion] We failed to detect a significant difference in muscle mass due to resistance exercise with LEAA supplementation in post-gastrectomy patients. However, resistance exercise with LEAA supplementation might be beneficial for muscle strength recovery and QOL improvements.PMID:38694013 | PMC:PMC11060767 | DOI:10.1589/jpts.36.218 (Source: Cancer Control)
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Atsushi Sawada Kentaro Yoneta Eri Togashi Shogo Asaka Riho Tada Takaaki Asada Seiichi Son Makoto Tayama Masami Kimura Satoshi Fujita Source Type: research

Smoothed Nested Testing on Directed Acyclic Graphs
Biometrika. 2022 Jun;109(2):457-471. doi: 10.1093/biomet/asab041. Epub 2021 Jul 2.ABSTRACTWe consider the problem of multiple hypothesis testing when there is a logical nested structure to the hypotheses. When one hypothesis is nested inside another, the outer hypothesis must be false if the inner hypothesis is false. We model the nested structure as a directed acyclic graph, including chain and tree graphs as special cases. Each node in the graph is a hypothesis and rejecting a node requires also rejecting all of its ancestors. We propose a general framework for adjusting node-level test statistics using the known logical...
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: J H Loper L Lei W Fithian W Tansey Source Type: research

The nonvesicular sterol transporter Aster-C plays a minor role in whole body cholesterol balance
DISCUSSION: Collectively, these data indicate nominal effects of Aster-C on whole body cholesterol transport and metabolism under divergent dietary cholesterol conditions. These results strongly suggest that Aster-C alone is not sufficient to control whole body cholesterol balance, but can modestly impact circulating cortisol and bile acid levels when dietary cholesterol is limited.PMID:38694206 | PMC:PMC11061533 | DOI:10.3389/fphys.2024.1371096 (Source: Cancer Control)
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Rakhee Banerjee Rachel C Hohe Shijie Cao Bryan M Jung Anthony J Horak Iyappan Ramachandiran William J Massey Venkateshwari Varadharajan Natalie I Zajczenko Amy C Burrows Sumita Dutta Maryam Goudarzi Kala Mahen Abigail Carter Robert N Helsley Scott M Gordo Source Type: research

Pre-Treatment Knowledge and Side-Effects Experienced during Chemotherapy for Breast Cancer in a Nigerian Tertiary Hospital
CONCLUSION: Majority of the patients were aware of the side effects of chemotherapy. Having knowledge about side effects was associated with faster recovery. Pre-Chemotherapy counselling should be done routinely for patients starting on chemotherapy.PMID:38694219 | PMC:PMC11058440 | DOI:10.60787/NMJ-62-4-37 (Source: Cancer Control)
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Abbas Abdus-Salam Atara Ntekim Sharif Folorunso Ayorinde Folasire Mutiu Jimoh Adeniyi Adenipekun Source Type: research

Fractionated stereotactic radiotherapy of intracranial postoperative cavities after resection of brain metastases - Clinical outcome and prognostic factors
CONCLUSION: FSRT after surgical resection of BM is an effective and safe treatment approach with excellent local control and acceptable toxicity. Further prospective randomized trials are needed to establish standardized therapeutic guidelines.PMID:38694237 | PMC:PMC11061678 | DOI:10.1016/j.ctro.2024.100782 (Source: Cancer Control)
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: L Hahnemann A Kr ämer C Fink C Jungk M Thomas P Christopoulos J W Lischalk J Meis J H örner-Rieber T Eichkorn M Deng K Lang A Paul E Meixner F Weykamp J Debus L K önig Source Type: research

Assessment of species distribution and virulence factors of oral fungal carriage among hospitalized patients with COVID-19: a case-control study
CONCLUSIONS: It is crucial to understand the way that virulence factors of oral fungal carriage act in COVID-19 patients in order to come up with novel antifungal medications, identify the contributing factors to drug resistance, and manage clinical outcomes.PMID:38694283 | PMC:PMC11060290 | DOI:10.1097/MS9.0000000000001956 (Source: Cancer Control)
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Zahra Ramezanalipour Seyed Jamal Hashemi Roshanak Daie Ghazvini Mohammad Shenagari Meysam Sharifdini Hamid Salehiniya Mohammad-Hossein Keivanlou Keyhan Ashrafi Davoud Roostaei Fariborz Mansour Ghanaei Elahe Sasani Zahra Rafat Source Type: research