Liraglutide and not lifestyle intervention reduces soluble CD163 after comparable weight loss in obese participants with prediabetes or type 2 diabetes mellitus
The GLP-1 receptor agonist liraglutide is used to treat hyperglycemia in type 2 diabetes but is also known to induce weight loss, preserve the beta cell and reduce cardiovascular risk. The mechanisms underlyin... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 29, 2024 Category: Cardiology Authors: Helene Grannes, Thor Ueland, Paola Simeone, Rossella Liani, Maria Teresa Guagnano, P ål Aukrust, Annika E. Michelsen, Kåre Birkeland, Augusto di Castelnuovo, Francesco Cipollone, Agostino Consoli, Bente Halvorsen, Ida Gregersen and Francesca Santilli Tags: Research Source Type: research

The prognostic impact of insulin resistance surrogates in patients with acute myocardial infarction with and without type 2 diabetes
Cardiovascular disease is the major cause of morbidity and mortality, particularly in type 2 diabetes mellitus (T2DM). Novel markers of insulin resistance and progression of atherosclerosis include the triglyc... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 29, 2024 Category: Cardiology Authors: Dominika Rokicka, Bartosz Hudzik, Marta Wr óbel, Tomasz Stołtny, Dorota Stołtny, Alicja Nowowiejska-Wiewióra, Sonia Rokicka, Mariusz Gąsior and Krzysztof Strojek Tags: Research Source Type: research

Glycemic control and clinical outcomes in diabetic patients with heart failure and reduced ejection fraction: insight from ventricular remodeling using cardiac MRI
Glycemic control, as measured by glycosylated hemoglobin (HbA1c), is an important biomarker to evaluate diabetes severity and is believed to be associated with heart failure development. Type 2 diabetes mellit... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 29, 2024 Category: Cardiology Authors: Ke Shi, Ge Zhang, Hang Fu, Xue-Ming Li, Yue Gao, Rui Shi, Hua-Yan Xu, Yuan Li, Ying-Kun Guo and Zhi-Gang Yang Tags: Research Source Type: research

Association of the triglyceride-glucose index with early-onset atherosclerotic cardiovascular disease events and all-cause mortality: a prospective cohort study
The association between the triglyceride glucose (TyG) index and the risk of early-onset atherosclerotic cardiovascular disease (ASCVD) events or all-cause mortality in young and middle-aged people is not full... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 29, 2024 Category: Cardiology Authors: Qiqi Hou, Qi Qi, Quanle Han, Jie Yu, Jianmei Wu, Hui Yang, Shuohua Chen, Shouling Wu and Kangbo Li Tags: Research Source Type: research

Ketone body levels and its associations with cardiac markers following an acute myocardial infarction: a post hoc analysis of the EMMY trial
Sodium-glucose co-transporter 2 inhibitors (SGLT2i) have been suggested to exert cardioprotective effects in patients with heart failure, possibly by improving the metabolism of ketone bodies in the myocardium. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 27, 2024 Category: Cardiology Authors: Faisal Aziz, Norbert J. Tripolt, Peter N. Pferschy, Hubert Scharnagl, Mahmoud Abdellatif, Abderrahim Oulhaj, Martin Benedikt, Ewald Kolesnik, Dirk von Lewinski and Harald Sourij Tags: Research Source Type: research

Sex-specific differences in myocardial glucose metabolic rate in non-diabetic, pre-diabetic and type 2 diabetic subjects
Evidence has shown that women with type 2 diabetes (T2DM) have a higher excess risk for cardiovascular disease (CVD) than men with T2DM. Subjects with either T2DM or prediabetes exhibit myocardial insulin resi... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 26, 2024 Category: Cardiology Authors: Elena Succurro, Patrizia Vizza, Francesco Cicone, Velia Cassano, Mattia Massimino, Federica Giofr è, Teresa Vanessa Fiorentino, Maria Perticone, Angela Sciacqua, Pietro Hiram Guzzi, Pierangelo Veltri, Francesco Andreozzi, Giuseppe Lucio Cascini and Giorg Tags: Research Source Type: research

Stroke incidence increases with diabetic retinopathy severity and macular edema in type 1 diabetes
As the retina is suggested to mirror the brain, we hypothesized that diabetic retinopathy and macular edema are indicative of stroke risk in type 1 diabetes and sought to assess this association in individuals... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 25, 2024 Category: Cardiology Authors: Marika I Eriksson, Kustaa Hietala, Paula Summanen, Valma Harjutsalo, Jukka Putaala, Anni Ylinen, Stefanie H ägg-Holmberg, Per-Henrik Groop and Lena M Thorn Tags: Research Source Type: research

Single-cell insights: pioneering an integrated atlas of chromatin accessibility and transcriptomic landscapes in diabetic cardiomyopathy
Diabetic cardiomyopathy (DCM) poses a growing health threat, elevating heart failure risk in diabetic individuals. Understanding DCM is crucial, with fibroblasts and endothelial cells playing pivotal roles in ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 25, 2024 Category: Cardiology Authors: Qiang Su, Wanzhong Huang, Yuan Huang, Rixin Dai, Chen Chang, Qiu-Yan Li, Hao Liu, Zhenhao Li, Yuxiang Zhao, Qiang Wu and Di-Guang Pan Tags: Research Source Type: research

BAG3 promotes proliferation and migration of arterial smooth muscle cells by regulating STAT3 phosphorylation in diabetic vascular remodeling
Diabetic vascular remodeling is the most important pathological basis of diabetic cardiovascular complications. The accumulation of advanced glycation end products (AGEs) caused by elevated blood glucose promo... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 25, 2024 Category: Cardiology Authors: Xinyue Huang, Jiayan Guo, Anqi Ning, Naijin Zhang and Yingxian Sun Tags: Research Source Type: research

Associations between cardiometabolic indices and the risk of diabetic kidney disease in patients with type 2 diabetes
This study was designed to assess the associations between emerging cardiometabolic indices —the atherogenic index of plasma (AIP), the stress hyperglycemia ratio (SHR), the triglyceride-glucose (TyG) index, an... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 25, 2024 Category: Cardiology Authors: Han Yan, Qing Zhou, Yaqiong Wang, Yifan Tu, Yuxin Zhao, Jie Yu, Kuangyang Chen, Yepeng Hu, Qiao Zhou, Wen Zhang and Chao Zheng Tags: Research Source Type: research

Effects of the stress hyperglycemia ratio on long-term mortality in patients with triple-vessel disease and acute coronary syndrome
Risk assessment for triple-vessel disease (TVD) remain challenging. Stress hyperglycemia represents the regulation of glucose metabolism in response to stress, and stress hyperglycemia ratio (SHR) is recently ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 25, 2024 Category: Cardiology Authors: Yu Zhang, Lei Guo, Hao Zhu, Lin Jiang, Lianjun Xu, Dong Wang, Yin Zhang, Xueyan Zhao, Kai Sun, Channa Zhang, Wei Zhao, Rutai Hui, Runlin Gao, Jizheng Wang, Jinqing Yuan, Yunlong Xia & hellip; Tags: Research Source Type: research

Association between triglyceride-glucose related indices with the all-cause and cause-specific mortality among the population with metabolic syndrome
Triglyceride-glucose (TyG) index has been determined to play a role in the onset of metabolic syndrome (MetS). Whether the TyG index and TyG with the combination of obesity indicators are associated with the c... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 24, 2024 Category: Cardiology Authors: Xiaoyuan Wei, Yu Min, Ge Song, Xin Ye and Lei Liu Tags: Research Source Type: research

Systolic blood pressure status modifies the associations between the triglyceride-glucose index and incident cardiovascular disease: a national cohort study in China
The triglyceride-glucose (TyG) index and blood pressure (BP) are correlated and serve as risk factors for cardiovascular disease (CVD). The potential impact of BP status on the association between the TyG inde... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 24, 2024 Category: Cardiology Authors: Weida Qiu, Anping Cai, Liwen Li and Yingqing Feng Tags: Research Source Type: research

The additive effect of metabolic syndrome on left ventricular impairment in patients with obstructive coronary artery disease assessed by 3.0 T cardiac magnetic resonance feature tracking
This study aimed to exp... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 23, 2024 Category: Cardiology Authors: Chen-Yan Min, Yue Gao, Yi-Ning Jiang, Ying-Kun Guo, Ke Shi, Zhi ‑Gang Yang and Yuan Li Tags: Research Source Type: research

Association between diabetes mellitus and primary restenosis following endovascular treatment: a comprehensive meta-analysis of randomized controlled trials
Diabetes mellitus (DM) is thought to be closely related to arterial stenotic or occlusive disease caused by atherosclerosis. However, there is still no definitive clinical evidence to confirm that patients wit... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 22, 2024 Category: Cardiology Authors: Xiaolei Sun, Cheng Zhang, Yarong Ma, Yanzheng He, Xiaodong Zhang and Jianbo Wu Tags: Research Source Type: research