Disrupted Rotational Perception During Simultaneous Stimulation of Rotation and Inertia
In this study, we analyzed the perceptual responses of 20 participants after pairwise rotational experiments, comprised of four control and four test sessions. In both control and test sessions, participants underwent clockwise and counterclockwise rotations in head-down and head-up positions. The difference between the control and test sessions was the head re-orientation relative to gravity after rotations, thereby providing only rotational cues in the control sessions and both rotational and inertial cues in the test sessions. The accuracy of perceptual responses was calculated by comparing the direction of rotational a...
Source: Cerebellum - May 3, 2024 Category: Neuroscience Authors: Ju-Young Lee So-Yeon Yun Yu-Jin Koo Jung-Mi Song Hyo-Jung Kim Jeong-Yoon Choi Ji-Soo Kim Source Type: research

Single-Session Cerebellar Transcranial Direct Current Stimulation Improves Postural Stability and Reduces Ataxia Symptoms in Spinocerebellar Ataxia
In conclusion, our study suggests that a single session of ctDCS, in combination with postural training, can enhance balance and alleviate ataxia symptoms in individuals with cerebellar ataxia. This study was approved by the local research ethics committee (No. 2.877.813) and registered on clinicaltrials.org (NCT04039048 - https://www.clinicaltrials.gov/study/NCT04039048 ) on 2019-07-28.PMID:38693314 | DOI:10.1007/s12311-024-01696-9 (Source: Cerebellum)
Source: Cerebellum - May 1, 2024 Category: Neuroscience Authors: Rodrigo Brito Jo ão Victor Fabrício Aurine Araujo Gabriel Barreto Adriana Baltar K átia Monte-Silva Source Type: research

Single-Session Cerebellar Transcranial Direct Current Stimulation Improves Postural Stability and Reduces Ataxia Symptoms in Spinocerebellar Ataxia
In conclusion, our study suggests that a single session of ctDCS, in combination with postural training, can enhance balance and alleviate ataxia symptoms in individuals with cerebellar ataxia. This study was approved by the local research ethics committee (No. 2.877.813) and registered on clinicaltrials.org (NCT04039048 - https://www.clinicaltrials.gov/study/NCT04039048 ) on 2019-07-28.PMID:38693314 | DOI:10.1007/s12311-024-01696-9 (Source: Cerebellum)
Source: Cerebellum - May 1, 2024 Category: Neuroscience Authors: Rodrigo Brito Jo ão Victor Fabrício Aurine Araujo Gabriel Barreto Adriana Baltar K átia Monte-Silva Source Type: research

Single-Session Cerebellar Transcranial Direct Current Stimulation Improves Postural Stability and Reduces Ataxia Symptoms in Spinocerebellar Ataxia
In conclusion, our study suggests that a single session of ctDCS, in combination with postural training, can enhance balance and alleviate ataxia symptoms in individuals with cerebellar ataxia. This study was approved by the local research ethics committee (No. 2.877.813) and registered on clinicaltrials.org (NCT04039048 - https://www.clinicaltrials.gov/study/NCT04039048 ) on 2019-07-28.PMID:38693314 | DOI:10.1007/s12311-024-01696-9 (Source: Cerebellum)
Source: Cerebellum - May 1, 2024 Category: Neuroscience Authors: Rodrigo Brito Jo ão Victor Fabrício Aurine Araujo Gabriel Barreto Adriana Baltar K átia Monte-Silva Source Type: research

The Evolution of the Optimization of Cognitive and Social Functions in the Cerebellum and Thereby the Rise of Homo sapiens Through Cumulative Culture
Cerebellum. 2024 Apr 27. doi: 10.1007/s12311-024-01692-z. Online ahead of print.ABSTRACTThe evolution of the prominent role of the cerebellum in the development of composite tools, and cumulative culture, leading to the rise of Homo sapiens is examined. Following Stout and Hecht's (2017) detailed description of stone-tool making, eight key repetitive involvements of the cerebellum are highlighted. These key cerebellar learning involvements include the following: (1) optimization of cognitive-social control, (2) prediction (3) focus of attention, (4) automaticity of smoothness, appropriateness, and speed of movement and cog...
Source: Cerebellum - April 27, 2024 Category: Neuroscience Authors: Larry Vandervert Mario Manto Michael Adamaszek Chiara Ferrari Andrea Ciricugno Zaira Cattaneo Source Type: research

The Evolution of the Optimization of Cognitive and Social Functions in the Cerebellum and Thereby the Rise of Homo sapiens Through Cumulative Culture
Cerebellum. 2024 Apr 27. doi: 10.1007/s12311-024-01692-z. Online ahead of print.ABSTRACTThe evolution of the prominent role of the cerebellum in the development of composite tools, and cumulative culture, leading to the rise of Homo sapiens is examined. Following Stout and Hecht's (2017) detailed description of stone-tool making, eight key repetitive involvements of the cerebellum are highlighted. These key cerebellar learning involvements include the following: (1) optimization of cognitive-social control, (2) prediction (3) focus of attention, (4) automaticity of smoothness, appropriateness, and speed of movement and cog...
Source: Cerebellum - April 27, 2024 Category: Neuroscience Authors: Larry Vandervert Mario Manto Michael Adamaszek Chiara Ferrari Andrea Ciricugno Zaira Cattaneo Source Type: research

The Evolution of the Optimization of Cognitive and Social Functions in the Cerebellum and Thereby the Rise of Homo sapiens Through Cumulative Culture
Cerebellum. 2024 Apr 27. doi: 10.1007/s12311-024-01692-z. Online ahead of print.ABSTRACTThe evolution of the prominent role of the cerebellum in the development of composite tools, and cumulative culture, leading to the rise of Homo sapiens is examined. Following Stout and Hecht's (2017) detailed description of stone-tool making, eight key repetitive involvements of the cerebellum are highlighted. These key cerebellar learning involvements include the following: (1) optimization of cognitive-social control, (2) prediction (3) focus of attention, (4) automaticity of smoothness, appropriateness, and speed of movement and cog...
Source: Cerebellum - April 27, 2024 Category: Neuroscience Authors: Larry Vandervert Mario Manto Michael Adamaszek Chiara Ferrari Andrea Ciricugno Zaira Cattaneo Source Type: research

The Role of Verbal Fluency in the Cerebellar Cognitive Affective Syndrome Scale in Friedreich Ataxia
This study explored the relationship between performance on the CCAS-S and clinical metrics of disease severity in 57 adults with FRDA. In addition, this study explored the relationship between measures of intelligibility and naturalness of speech and scores on the CCAS-S in a subgroup of 39 individuals with FRDA. We demonstrated a significant relationship between clinical metrics and performance on the CCAS-S. In addition, we confirmed the items that returned the greatest rate of failure were based on Verbal Fluency Tasks, revealing a significant relationship between these items and measures of speech. Measures of speech ...
Source: Cerebellum - April 20, 2024 Category: Neuroscience Authors: Louise A Corben Eliza Blomfield Geneieve Tai Hiba Bilal Ian H Harding Nellie Georgiou-Karistianis Martin B Delatycki Adam P Vogel Source Type: research

The Role of Verbal Fluency in the Cerebellar Cognitive Affective Syndrome Scale in Friedreich Ataxia
This study explored the relationship between performance on the CCAS-S and clinical metrics of disease severity in 57 adults with FRDA. In addition, this study explored the relationship between measures of intelligibility and naturalness of speech and scores on the CCAS-S in a subgroup of 39 individuals with FRDA. We demonstrated a significant relationship between clinical metrics and performance on the CCAS-S. In addition, we confirmed the items that returned the greatest rate of failure were based on Verbal Fluency Tasks, revealing a significant relationship between these items and measures of speech. Measures of speech ...
Source: Cerebellum - April 20, 2024 Category: Neuroscience Authors: Louise A Corben Eliza Blomfield Geneieve Tai Hiba Bilal Ian H Harding Nellie Georgiou-Karistianis Martin B Delatycki Adam P Vogel Source Type: research

The Role of Verbal Fluency in the Cerebellar Cognitive Affective Syndrome Scale in Friedreich Ataxia
This study explored the relationship between performance on the CCAS-S and clinical metrics of disease severity in 57 adults with FRDA. In addition, this study explored the relationship between measures of intelligibility and naturalness of speech and scores on the CCAS-S in a subgroup of 39 individuals with FRDA. We demonstrated a significant relationship between clinical metrics and performance on the CCAS-S. In addition, we confirmed the items that returned the greatest rate of failure were based on Verbal Fluency Tasks, revealing a significant relationship between these items and measures of speech. Measures of speech ...
Source: Cerebellum - April 20, 2024 Category: Neuroscience Authors: Louise A Corben Eliza Blomfield Geneieve Tai Hiba Bilal Ian H Harding Nellie Georgiou-Karistianis Martin B Delatycki Adam P Vogel Source Type: research

The Role of Verbal Fluency in the Cerebellar Cognitive Affective Syndrome Scale in Friedreich Ataxia
This study explored the relationship between performance on the CCAS-S and clinical metrics of disease severity in 57 adults with FRDA. In addition, this study explored the relationship between measures of intelligibility and naturalness of speech and scores on the CCAS-S in a subgroup of 39 individuals with FRDA. We demonstrated a significant relationship between clinical metrics and performance on the CCAS-S. In addition, we confirmed the items that returned the greatest rate of failure were based on Verbal Fluency Tasks, revealing a significant relationship between these items and measures of speech. Measures of speech ...
Source: Cerebellum - April 20, 2024 Category: Neuroscience Authors: Louise A Corben Eliza Blomfield Geneieve Tai Hiba Bilal Ian H Harding Nellie Georgiou-Karistianis Martin B Delatycki Adam P Vogel Source Type: research

The Role of Cognitive Reserve in Protecting Cerebellar Volumes of Older Adults with mild Cognitive Impairment
This study suggests that a higher cognitive reserve is associated with specific cerebellar lobule volumes and that Working activity may play a predominant role in this association. These findings contribute to the understanding of the relationship between cerebellar volumes and cognitive reserve, highlighting the potential modulatory role of Working activity on cerebellum response to cognitive decline.PMID:38639874 | DOI:10.1007/s12311-024-01695-w (Source: Cerebellum)
Source: Cerebellum - April 19, 2024 Category: Neuroscience Authors: Maria Devita Giulia Debiasi Mariagiulia Anglani Chiara Ceolin Ilaria Mazzonetto Chiara Begliomini Simone Cauzzo Cecilia Raffaelli Alessandro Lazzarin Adele Ravelli Alessandra Bordignon Marina De Rui Giuseppe Sergi Alessandra Bertoldo Daniela Mapelli Aless Source Type: research

Role of the Cerebellum in the Construction of Functional and Geometrical Spaces
Cerebellum. 2024 Apr 16. doi: 10.1007/s12311-024-01693-y. Online ahead of print.ABSTRACTThe perceptual and motor systems appear to have a set of movement primitives that exhibit certain geometric and kinematic invariances. Complex patterns and mental representations can be produced by (re)combining some simple motor elements in various ways using basic operations, transformations, and respecting a set of laws referred to as kinematic laws of motion. For example, point-to-point hand movements are characterized by straight hand paths with single-peaked-bell-shaped velocity profiles, whereas hand speed profiles for curved tra...
Source: Cerebellum - April 16, 2024 Category: Neuroscience Authors: Eya Torkhani Langlois Daniel Bennequin Giovanni de Marco Source Type: research

Role of the Cerebellum in the Construction of Functional and Geometrical Spaces
Cerebellum. 2024 Apr 16. doi: 10.1007/s12311-024-01693-y. Online ahead of print.ABSTRACTThe perceptual and motor systems appear to have a set of movement primitives that exhibit certain geometric and kinematic invariances. Complex patterns and mental representations can be produced by (re)combining some simple motor elements in various ways using basic operations, transformations, and respecting a set of laws referred to as kinematic laws of motion. For example, point-to-point hand movements are characterized by straight hand paths with single-peaked-bell-shaped velocity profiles, whereas hand speed profiles for curved tra...
Source: Cerebellum - April 16, 2024 Category: Neuroscience Authors: Eya Torkhani Langlois Daniel Bennequin Giovanni de Marco Source Type: research

Role of the Cerebellum in the Construction of Functional and Geometrical Spaces
Cerebellum. 2024 Apr 16. doi: 10.1007/s12311-024-01693-y. Online ahead of print.ABSTRACTThe perceptual and motor systems appear to have a set of movement primitives that exhibit certain geometric and kinematic invariances. Complex patterns and mental representations can be produced by (re)combining some simple motor elements in various ways using basic operations, transformations, and respecting a set of laws referred to as kinematic laws of motion. For example, point-to-point hand movements are characterized by straight hand paths with single-peaked-bell-shaped velocity profiles, whereas hand speed profiles for curved tra...
Source: Cerebellum - April 16, 2024 Category: Neuroscience Authors: Eya Torkhani Langlois Daniel Bennequin Giovanni de Marco Source Type: research