Olaparib and niraparib as maintenance therapy in patients with newly diagnosed and platinum-sensitive recurrent ovarian cancer: A single-center study in China
CONCLUSIONS: Olaparib and niraparib were effective in patients with ovarian cancer without any new safety signals except for skin pigmentation. In patients with BRCAm, the 24-month PFS of the PARPi used in the PSR-M setting was even higher than that used in the FL-M setting.PMID:38679485 | DOI:10.1097/CM9.0000000000003125 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 28, 2024 Category: General Medicine Authors: Dengfeng Wang Xunwei Shi Jiao Pei Can Zhang Liping Peng Jie Zhang Jing Zheng Chunrong Peng Xiaoqiao Huang Xiaoshi Liu Hong Liu Guonan Zhang Source Type: research

Precise capture of circulating endometrial cells in endometriosis
CONCLUSION: The number and characteristics of CECs are related to the clinical course characteristics of patients with EM, such as pain and changes in lesion size, and may be used as biomarkers for personalized treatment and management of EM in the future.PMID:38679794 | DOI:10.1097/CM9.0000000000002910 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 28, 2024 Category: General Medicine Authors: Shang Wang Hongyan Cheng Honglan Zhu Xiaoming Yu Xue Ye Xiaohong Chang Source Type: research

Olaparib and niraparib as maintenance therapy in patients with newly diagnosed and platinum-sensitive recurrent ovarian cancer: A single-center study in China
CONCLUSIONS: Olaparib and niraparib were effective in patients with ovarian cancer without any new safety signals except for skin pigmentation. In patients with BRCAm, the 24-month PFS of the PARPi used in the PSR-M setting was even higher than that used in the FL-M setting.PMID:38679485 | DOI:10.1097/CM9.0000000000003125 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 28, 2024 Category: General Medicine Authors: Dengfeng Wang Xunwei Shi Jiao Pei Can Zhang Liping Peng Jie Zhang Jing Zheng Chunrong Peng Xiaoqiao Huang Xiaoshi Liu Hong Liu Guonan Zhang Source Type: research

Precise capture of circulating endometrial cells in endometriosis
CONCLUSION: The number and characteristics of CECs are related to the clinical course characteristics of patients with EM, such as pain and changes in lesion size, and may be used as biomarkers for personalized treatment and management of EM in the future.PMID:38679794 | DOI:10.1097/CM9.0000000000002910 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 28, 2024 Category: General Medicine Authors: Shang Wang Hongyan Cheng Honglan Zhu Xiaoming Yu Xue Ye Xiaohong Chang Source Type: research

Olaparib and niraparib as maintenance therapy in patients with newly diagnosed and platinum-sensitive recurrent ovarian cancer: A single-center study in China
CONCLUSIONS: Olaparib and niraparib were effective in patients with ovarian cancer without any new safety signals except for skin pigmentation. In patients with BRCAm, the 24-month PFS of the PARPi used in the PSR-M setting was even higher than that used in the FL-M setting.PMID:38679485 | DOI:10.1097/CM9.0000000000003125 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 28, 2024 Category: General Medicine Authors: Dengfeng Wang Xunwei Shi Jiao Pei Can Zhang Liping Peng Jie Zhang Jing Zheng Chunrong Peng Xiaoqiao Huang Xiaoshi Liu Hong Liu Guonan Zhang Source Type: research

Precise capture of circulating endometrial cells in endometriosis
CONCLUSION: The number and characteristics of CECs are related to the clinical course characteristics of patients with EM, such as pain and changes in lesion size, and may be used as biomarkers for personalized treatment and management of EM in the future.PMID:38679794 | DOI:10.1097/CM9.0000000000002910 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 28, 2024 Category: General Medicine Authors: Shang Wang Hongyan Cheng Honglan Zhu Xiaoming Yu Xue Ye Xiaohong Chang Source Type: research

Olaparib and niraparib as maintenance therapy in patients with newly diagnosed and platinum-sensitive recurrent ovarian cancer: A single-center study in China
CONCLUSIONS: Olaparib and niraparib were effective in patients with ovarian cancer without any new safety signals except for skin pigmentation. In patients with BRCAm, the 24-month PFS of the PARPi used in the PSR-M setting was even higher than that used in the FL-M setting.PMID:38679485 | DOI:10.1097/CM9.0000000000003125 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 28, 2024 Category: General Medicine Authors: Dengfeng Wang Xunwei Shi Jiao Pei Can Zhang Liping Peng Jie Zhang Jing Zheng Chunrong Peng Xiaoqiao Huang Xiaoshi Liu Hong Liu Guonan Zhang Source Type: research

Precise capture of circulating endometrial cells in endometriosis
CONCLUSION: The number and characteristics of CECs are related to the clinical course characteristics of patients with EM, such as pain and changes in lesion size, and may be used as biomarkers for personalized treatment and management of EM in the future.PMID:38679794 | DOI:10.1097/CM9.0000000000002910 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 28, 2024 Category: General Medicine Authors: Shang Wang Hongyan Cheng Honglan Zhu Xiaoming Yu Xue Ye Xiaohong Chang Source Type: research

Temporal trend in mortality due to congenital heart disease in China from 2008 to 2021
CONCLUSIONS: CHD mortality in China has dramatically decreased from 2008 to 2021. The slower decrease in CHD mortality in the central and western regions than in the eastern regions suggested that public health policymakers should pay more attention to health resources and health education for central and western regions.PMID:38663857 | DOI:10.1097/CM9.0000000000003057 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 25, 2024 Category: General Medicine Authors: Youping Tian Xiaojing Hu Qing Gu Miao Yang Pin Jia Xiaojing Ma Xiaoling Ge Quming Zhao Fang Liu Ming Ye Weili Yan Guoying Huang Source Type: research

Temporal trend in mortality due to congenital heart disease in China from 2008 to 2021
CONCLUSIONS: CHD mortality in China has dramatically decreased from 2008 to 2021. The slower decrease in CHD mortality in the central and western regions than in the eastern regions suggested that public health policymakers should pay more attention to health resources and health education for central and western regions.PMID:38663857 | DOI:10.1097/CM9.0000000000003057 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 25, 2024 Category: General Medicine Authors: Youping Tian Xiaojing Hu Qing Gu Miao Yang Pin Jia Xiaojing Ma Xiaoling Ge Quming Zhao Fang Liu Ming Ye Weili Yan Guoying Huang Source Type: research

Temporal trend in mortality due to congenital heart disease in China from 2008 to 2021
CONCLUSIONS: CHD mortality in China has dramatically decreased from 2008 to 2021. The slower decrease in CHD mortality in the central and western regions than in the eastern regions suggested that public health policymakers should pay more attention to health resources and health education for central and western regions.PMID:38663857 | DOI:10.1097/CM9.0000000000003057 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 25, 2024 Category: General Medicine Authors: Youping Tian Xiaojing Hu Qing Gu Miao Yang Pin Jia Xiaojing Ma Xiaoling Ge Quming Zhao Fang Liu Ming Ye Weili Yan Guoying Huang Source Type: research

Vonoprazan 10  mg or 20 mg vs. lansoprazole 15 mg as maintenance therapy in Asian patients with healed erosive esophagitis: A randomized controlled trial
CONCLUSION: Vonoprazan maintenance therapy was well-tolerated and noninferior to lansoprazole for preventing EE recurrence in Asian patients with healed EE.TRIAL REGISTRATION: https://clinicaltrials.gov; NCT02388737.PMID:38654422 | DOI:10.1097/CM9.0000000000003068 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 24, 2024 Category: General Medicine Authors: Yinglian Xiao Jiaming Qian Shutian Zhang Ning Dai Hoon Jai Chun Chengtang Chiu Chui Fung Chong Nobuo Funao Yuuichi Sakurai Jessica D Eisner Li Xie Minhu Chen Source Type: research

Vonoprazan 10  mg or 20 mg vs. lansoprazole 15 mg as maintenance therapy in Asian patients with healed erosive esophagitis: A randomized controlled trial
CONCLUSION: Vonoprazan maintenance therapy was well-tolerated and noninferior to lansoprazole for preventing EE recurrence in Asian patients with healed EE.TRIAL REGISTRATION: https://clinicaltrials.gov; NCT02388737.PMID:38654422 | DOI:10.1097/CM9.0000000000003068 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 24, 2024 Category: General Medicine Authors: Yinglian Xiao Jiaming Qian Shutian Zhang Ning Dai Hoon Jai Chun Chengtang Chiu Chui Fung Chong Nobuo Funao Yuuichi Sakurai Jessica D Eisner Li Xie Minhu Chen Source Type: research

Biliary spontaneous dislodgement spiral stent for short-term biliary drainage in patients undergoing complete stone removal: A randomized controlled study
Chin Med J (Engl). 2024 Apr 24. doi: 10.1097/CM9.0000000000003089. Online ahead of print.NO ABSTRACTPMID:38654406 | DOI:10.1097/CM9.0000000000003089 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 23, 2024 Category: General Medicine Authors: Liansong Ye Lifan Zhang Yi Mou Xianglei Yuan Wei Liu Chuncheng Wu Yonghong Luo Jiang Du Shuai Bai Jia Xie Qiongying Zhang Qinghua Tan Ling Liu Bing Hu Source Type: research

Shanghai Gynecologic Oncology Group's Consensus on the academic and industry's clinical trial types
Chin Med J (Engl). 2024 Apr 24. doi: 10.1097/CM9.0000000000003146. Online ahead of print.NO ABSTRACTPMID:38654409 | DOI:10.1097/CM9.0000000000003146 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - April 23, 2024 Category: General Medicine Authors: Tingyan Shi Jihong Liu Jianqing Zhu Xipeng Wang Wei Jiang Xin Lu Weiwei Feng Shengtao Zhou Yang Shen Gang Chen Zhenyu Wu Dongling Zou Peng Wu Huijuan Yang Sufang Wu Tao Zhu Huaying Wang Yingli Zhang Lihua Qiu Xiaoqing Guo Libing Xiang Wei Zhang Yulan Ren Source Type: research