Basilic vein variation encountered during surgery for arm vein port: A case report
CONCLUSION: Venous variation is rare and requires detailed intraoperative and postoperative examination to ensure accuracy, so as not to affect subsequent treatment.PMID:38680270 | PMC:PMC11045501 | DOI:10.12998/wjcc.v12.i12.2086 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 29, 2024 Category: Cancer & Oncology Authors: Cheng-Da Hu Rui Lv Ya-Xin Zhao Ming-Hao Zhang Hong-Dou Zeng Yi-Wen Mao Source Type: research
Determining individual suitability for neoadjuvant systemic therapy in breast cancer patients through deep learning
CONCLUSIONS: Our results demonstrated the potential of BITES to aid in clinical treatment decisions and offer quantitative treatment insights. In our further research, these models should be validated in clinical settings and additional patient features as well as outcome measures should be studied in depth.PMID:38678522 | DOI:10.1007/s12094-024-03459-8 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 28, 2024 Category: Cancer & Oncology Authors: Enzhao Zhu Linmei Zhang Yixian Liu Tianyu Ji Jianmeng Dai Ruichen Tang Jiayi Wang Chunyu Hu Kai Chen Qianyi Yu Qiuyi Lu Zisheng Ai Source Type: research
The Influence of Inset and Shaping of Abdominal-Based Free Flap Breast Reconstruction on Patient-Reported Aesthetic Outcome Scores-A Systematic Review
Conclusions: Emphasis on the aesthetic outcome in terms of breast shape and symmetry, providing an individualized approach of flap inset, considering the contralateral breast's shape and volume, results in higher satisfaction scores.PMID:38673668 | PMC:PMC11051228 | DOI:10.3390/jcm13082395 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 27, 2024 Category: Cancer & Oncology Authors: Isabel Zucal Laura De Pellegrin Corrado Parodi Yves Harder Riccardo Schweizer Source Type: research
Abrogating PDK4 activates autophagy-dependent ferroptosis in breast cancer via ASK1/JNK pathway
CONCLUSION: To sum up, deficiency of PDK4 activated ASK1/JNK pathway to stimulate autophagy-dependent ferroptosis in breast cancer.PMID:38678126 | PMC:PMC11055733 | DOI:10.1007/s00432-024-05748-9 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 27, 2024 Category: Cancer & Oncology Authors: Wenbiao Shi Jian Wang Jianbin Chen Xiaoyan Jin Yuanfan Wang Linjun Yang Source Type: research
The Influence of Inset and Shaping of Abdominal-Based Free Flap Breast Reconstruction on Patient-Reported Aesthetic Outcome Scores-A Systematic Review
Conclusions: Emphasis on the aesthetic outcome in terms of breast shape and symmetry, providing an individualized approach of flap inset, considering the contralateral breast's shape and volume, results in higher satisfaction scores.PMID:38673668 | DOI:10.3390/jcm13082395 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 27, 2024 Category: Cancer & Oncology Authors: Isabel Zucal Laura De Pellegrin Corrado Parodi Yves Harder Riccardo Schweizer Source Type: research
Availability of genome-matched therapy based on clinical practice
CONCLUSION: This study demonstrated the usefulness of CGP for patients with sarcoma and HNC in addition to lung cancer in clinical practice. Performing CGP at the front line has the potential to improve the availability of genome-matched therapy.PMID:38668785 | DOI:10.1007/s10147-024-02533-z (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Naomi Hayashi Seiichi Mori Akihiro Ohmoto Ippei Fukada Masumi Yamazaki Mari Hosonaga Xiaofei Wang Arisa Ueki Kazuma Kiyotani Akiko Tonooka Kengo Takeuchi Shunji Takahashi Source Type: research
Association between serum α-Klotho levels and osteoarthritis prevalence among middle-aged and older adults: an analysis of the NHANES 2007-2016
CONCLUSION: Serum α-Klotho levels exhibit a significant negative linear correlation with the prevalence of osteoarthritis in middle-aged and elderly populations in the United States.PMID:38670226 | DOI:10.1016/j.rceng.2024.04.012 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Xu Qi Wang Jiale Li Hanzhi Gao Yuwan Source Type: research
Survival Outcomes in Thyroid Cancer Patients with Co-Occurring Breast Cancer: Evidence of Mortality Risk Attenuation
CONCLUSION: These findings suggest that hormone pathways may play a role in the co-occurrence of thyroid and breast cancers. Patients with TC coexisting with luminal A BC have higher survival rates. However, further studies on the mechanisms underlying the association between BC and TC are warranted.PMID:38670860 | DOI:10.1016/j.clbc.2024.04.002 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Matheus Wohlfahrt Baumgarten Iuri Martin Goemann Rafael Selbach Scheffel Ana Luiza Maia Source Type: research
Screening Mammography for Males With Elevated Breast Cancer Risk, Mutation Carriers, and Gynecomastia
CONCLUSION: Gynecomastia may be associated with an increased risk of breast cancer in carriers. Larger studies are needed to determine whether and when to screen male carriers.PMID:38670861 | DOI:10.1016/j.clbc.2024.03.014 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Ahuva Grubstein Marva Dahan Wael Jomar Tal Friehmann Shlomit Tamir Tzippy Shochat Eli Atar Tanir M Allweis Source Type: research
The Efficiency and Toxicity Of Anlotinib in Combination With Docetaxel Followed by Epirubicin and Cyclophosphamide Regimen as Neoadjuvant Treatment in IIB to IIIA Triple Negative Breast Cancer: A Single-Arm, Multicenter, Open-Label, Phase II Study
CONCLUSION: The combination of anlotinib and EC-T chemotherapy demonstrated tolerable side effects in the neoadjuvant treatment of early TNBC. pCR was higher than what has been reported in previous clinical studies of chemotherapy alone. This study provides additional rationale for using anlotinib plus docetaxel-epirubicin-based chemotherapy regimen in patients with early-stage TNBCs.PMID:38670862 | DOI:10.1016/j.clbc.2024.01.018 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Xi Chen Xinyu Wei Peizhuo Yao Yanbin Liu Haitao Guan Huafeng Kang Di Liu Yan Diao Xiaobin Ma Weili Min Changyou Shan Yang Zhao Fang Zhao Yuanyuan Chen Dong Xiao Qing She Youhuai Liu Yinbin Zhang Shuqun Zhang Source Type: research
Availability of genome-matched therapy based on clinical practice
CONCLUSION: This study demonstrated the usefulness of CGP for patients with sarcoma and HNC in addition to lung cancer in clinical practice. Performing CGP at the front line has the potential to improve the availability of genome-matched therapy.PMID:38668785 | DOI:10.1007/s10147-024-02533-z (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 26, 2024 Category: Cancer & Oncology Authors: Naomi Hayashi Seiichi Mori Akihiro Ohmoto Ippei Fukada Masumi Yamazaki Mari Hosonaga Xiaofei Wang Arisa Ueki Kazuma Kiyotani Akiko Tonooka Kengo Takeuchi Shunji Takahashi Source Type: research
Extrachromosomal circular DNA (eccDNA): from carcinogenesis to drug resistance
Clin Exp Med. 2024 Apr 25;24(1):83. doi: 10.1007/s10238-024-01348-6.ABSTRACTExtrachromosomal circular DNA (eccDNA) is a circular form of DNA that exists outside of the chromosome. Although it has only been a few decades since its discovery, in recent years, it has been found to have a close relationship with cancer, which has attracted widespread attention from researchers. Thus far, under the persistent research of researchers from all over the world, eccDNA has been found to play an important role in a variety of tumors, including breast cancer, lung cancer, ovarian cancer, etc. Herein, we review the sources of eccDNA, c...
Source: Clinical Genitourinary Cancer - April 25, 2024 Category: Cancer & Oncology Authors: Zhaoxing Li Daohai Qian Source Type: research
Noni enhances the anticancer activity of cyclophosphamide and suppresses myelotoxicity and hepatotoxicity in tumor-bearing mice
CONCLUSIONS: The present study suggested that CYL treatment can cause serious myelotoxicity and hepatic injury in cancer patients. In conclusion, the combined use of noni with CYL potentially enhances the antitumor activity of CYL and suppresses myelotoxicity and hepatotoxicity induced by CYL in tumor-bearing mice.PMID:38662247 | DOI:10.1007/s00432-024-05734-1 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 25, 2024 Category: Cancer & Oncology Authors: Mohammad Ali S N Manjula Ishfaq Mohiuddin K Mruthunjaya Faiyaz Shakeel Suhail Ahmad Mir Shahid Ud Din Wani Source Type: research
Precision medicine in colorectal cancer: Leveraging multi-omics, spatial omics, and artificial intelligence
Clin Chim Acta. 2024 Apr 23:119686. doi: 10.1016/j.cca.2024.119686. Online ahead of print.ABSTRACTColorectal cancer (CRC) is a leading cause of cancer-related deaths. Recent advancements in genomic technologies and analytical approaches have revolutionized CRC research, enabling precision medicine. This review highlights the integration of multi-omics, spatial omics, and artificial intelligence (AI) in advancing precision medicine for CRC. Multi-omics approaches have uncovered molecular mechanisms driving CRC progression, while spatial omics have provided insights into the spatial heterogeneity of gene expression in CRC ti...
Source: Clinical Genitourinary Cancer - April 25, 2024 Category: Cancer & Oncology Authors: Zishan Xu Wei Li Xiangyang Dong Yingying Chen Dan Zhang Jingnan Wang Lin Zhou Guoyang He Source Type: research
Targeting tumor markers in ovarian cancer treatment
Clin Chim Acta. 2024 Apr 23:119687. doi: 10.1016/j.cca.2024.119687. Online ahead of print.ABSTRACTOvarian cancers (OC) are the most common, lethal, and stage-dependent cancers at the global level, specifically in female patients. Targeted therapies involve the administration of drugs that specifically target the alterations in tumour cells responsible for their growth, proliferation, and metastasis, with the aim of treating particular patients. Presently, within the realm of gynaecological malignancies, specifically in breast and OCs, there exist various prospective therapeutic targets encompassing tumour-intrinsic signall...
Source: Clinical Genitourinary Cancer - April 25, 2024 Category: Cancer & Oncology Authors: Subham Preetam Sagar Mondal Swati Priya Jutishna Bora Seema Ramaniwas Sarves Rastagi Naeem F Qusty Saad Alghamdi Ahmad O Babalghith Abdullah Siddiqi Sumira Malik Source Type: research
