In-vitro effects of novel periodontal scalers with a planar ultrasonic piezoelectric transducer on periodontal biofilm removal, dentine surface roughness, and periodontal ligament fibroblasts adhesion
ConclusionsThe planar piezoelectric scaler prototypes are able to efficiently remove biofilm without dentine surface alterations, regardless of the operating frequency or instrument material.Clinical relevanceUltrasonic scalers based on a planar piezoelectric transducer might be an alternative to currently available ultrasonic scalers. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - May 3, 2024 Category: Dentistry Source Type: research

Association between blood ethylene oxide levels and the prevalence of periodontitis: evidence from NHANES 2013 –2014
ConclusionsThese findings suggest a correlation between HbEO levels and an increased susceptibility to periodontitis. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - May 2, 2024 Category: Dentistry Source Type: research

Quantitative evaluation of the impact of indoor relative humidity on deposition of aerosols generated during tooth grinding in a real-world clinical setting
ConclusionsIncreasing the IRH level can effectively promote the deposition of aerosol particles, with a return to baseline within 15  min after reaching 60% or above.Clinical RelevanceOur study suggested that maintaining IRH above 70% during the cleaning process, allowing natural recovery to ambient humidity levels within 15  min after cleaning, and taking basic precautions, may lead to an adequate reduction in the possible health risks of aerosol contamination. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - May 2, 2024 Category: Dentistry Source Type: research

Evaluation of salivary stress markers and inflammatory cytokine levels in peri-implantitis patients
ConclusionThe study findings suggest that psychological stress may increase the inflammation associated with peri-implantitis by affecting cytokine expression levels.Clinical relevanceTo prevent peri-implantitis or reduce its prevalence, it could be beneficial to evaluate stress levels and identify individuals experiencing stress. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - May 1, 2024 Category: Dentistry Source Type: research

Periodontal grading —estimation of responsiveness to therapy and progression of disease
ConclusionThe present data indicate that indirect evidence may lead to inaccuracies compared to direct evidence regarding the estimation of periodontal progression. However, indirect evidence seems to be more suitable in the estimation of responsiveness to therapy than direct evidence, helping to identify cases that are more likely to require additional therapies such as re-instrumentation or periodontal surgery.Clinical relevanceRegarding the estimation of disease progression and responsiveness to periodontal therapy, accuracy and reliability of both direct and indirect evidence are limited when grading periodontitis. (So...
Source: Clinical Oral Investigations - May 1, 2024 Category: Dentistry Source Type: research

Treatment of multiple adjacent gingival recessions using leucocyte- and platelet-rich fibrin with coronally advanced flap: a 12-month split-mouth controlled randomized clinical trial
ConclusionsThe current study concludes that L-PRF were equally effective as CTG in treating MAGRs in terms of RC and CRC. Additionally, RC and CRC outcomes appeared to be influenced by GMCEJ, PW, and RW.Clinical relevanceL-PRF could represent a feasible substitute for CTG in treating MAGRs. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - May 1, 2024 Category: Dentistry Source Type: research

Influence of malocclusion on OHRQoL in adolescents in initial orthodontic treatment phase
ConclusionsAt the beginning of orthodontic treatment, the OHRQoL slightly worsens, probably due to the discomfort and appearance of the appliances. However, 6 months after the start of orthodontic treatment, OHRQoL improved again in patients with severe malocclusion (IOTN 4 and 5), and approached baseline values.Clinical relevanceThe results help the clinician to better understand specific aspects of oral health that may be affected by different malocclusions, thereby improving the child ’s satisfaction and overall quality of life. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 30, 2024 Category: Dentistry Source Type: research

Identification of a novel de novo mutation in SOX4 for syndromic tooth agenesis
ConclusionsOur findings link a novelSOX4 mutation to syndromic tooth agenesis in CSS. This is the first report ofSOX4 missense mutation causing syndromic tooth agenesis.Clinical RelevanceThis study not only enhances our understanding of the pathogenic mutation for syndromic tooth agenesis but also provides genetic diagnosis and potential therapeutic insights for syndromic tooth agenesis. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 30, 2024 Category: Dentistry Source Type: research

The effects of NLRP3 inflammasome inhibition or knockout in experimental apical periodontitis induced in mice
ConclusionsNLRP3 inflammasome inhibition or knockout can attenuate the inflammatory events that result in the periapical lesion (AP) formation after pulpal exposure in mice.Clinical relevanceThe NLRP3 inflammasome may be a therapeutic target for AP, and new approaches may verify the impact of its inhibition (through intracanal medications or filling materials) on the bone repair process and treatment success. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 30, 2024 Category: Dentistry Source Type: research

Clinical Longevity of Obturators in Patients with Jaw Defects: a Retrospective Cohort Study
ConclusionsThe findings obtained in this study support the recommendation of using implant-supported obturators. Telescopic-crown attachments, either tooth- or implant-supported, seem to be favorable in terms of survival time. Attendance at a strict follow-up program seems to have a major influence on the longevity of the obturators.Clinical relevanceThe use of implant-supported obturators to cover permanent oral and maxillofacial defects is highly recommended. Additionally, the use of telescopic-crown attachments seems to be favorable in terms of survival time. Clasp-retained obturators and surgical splints should be used...
Source: Clinical Oral Investigations - April 30, 2024 Category: Dentistry Source Type: research

Changes in periodontal parameters of splinted versus non-splinted posterior teeth during ten years of supportive periodontal therapy – A retrospective evaluation
ConclusionsSplinting of periodontally compromised and mobile posterior teeth does not have any disadvantage regarding the clinical periodontal situation when regular SPT is applied. However, splint fractures occur very often.Clinical relevanceSplinting of posterior teeth is a treatment option in addition to active periodontal therapy when patients are disturbed by tooth mobility but splints have a high susceptibility to fracture. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 29, 2024 Category: Dentistry Source Type: research

Antimicrobial action, cytotoxicity and erosive potential of hypochlorous acid obtained from an electrolytic device compared with sodium hypochlorite
ConclusionsIt is possible to conclude that HClO obtained from an electrolytic device presented high antimicrobial activity and low cytotoxicity in both tested concentrations. 500 ppm HClO did not display erosion and showed great cleaning ability.Clinical relevanceThe use of 500 ppm hypochlorous acid may reduce unfavorable behavior of sodium hypochlorite whilst maintaining its antimicrobial action. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 29, 2024 Category: Dentistry Source Type: research

Pre-eruptive intramural resorption in unerupted teeth: a cone-beam computed tomography evaluation of prevalence and related factors
ConclusionPEIR should be suspected in transverse, inverted-angulated, centrally positioned unerupted teeth, particularly in molars, with no pericoronal space. Further monitoring through CBCT is recommended in such cases.Clinical relevanceThe management of unerupted teeth does not always involve surgical removal. Instead, they could be utilized for artificial eruption or tooth transplantation. The present study emphasizes the significance of early detection of PEIR. Clinical recommendations for screening PEIR in unerupted teeth are also proposed, which can be applied to routine plain radiographs. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 27, 2024 Category: Dentistry Source Type: research

Histological evaluation of nonsurgical periodontal treatment with and without the use of sodium hypochlorite / amino acids and cross-linked hyaluronic acid gels in dogs
ConclusionThe adjunctive subgingival application of sodium hypochlorite/amino acid and xHyA gels to SRP offers an innovative novel approach to enhance periodontal wound healing/regeneration.Clinical relevanceThe present findings have for the first-time shown histologic evidence for periodontal regeneration in support of this novel treatment modality. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 27, 2024 Category: Dentistry Source Type: research

Bleaching versus color change resistant adhesive in the discoloration of bracket-bonded tooth surfaces: an in vitro study
ConclusionsAfter coffee-induced enamel discoloration, bleaching of teeth bonded with TRXT produced acceptable color difference of the incisal, middle, and gingival regions of the crown. In teeth bonded with Orthocem, acceptable color difference was seen only in the middle of the crown.Clinical relevanceThe presented study will guide the clinician on how enamel discoloration side effect of fixed orthodontic appliance can reduce. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 27, 2024 Category: Dentistry Source Type: research