Composite Reconstruction With Irradiated Autograft Plus Total Hip Replacement After Type II Pelvic Resections for Tumors Is Feasible but Fraught With Complications
CONCLUSION: Composite reconstruction with extracorporeal irradiated autografts plus total hip replacement is a feasible reconstruction technique after Type II pelvic resections, although complications and reoperations were common. Although no reconstruction technique has been proven superior to other alternatives, the high risk of complications and reoperations associated with this technique should be considered when selecting from among possible alternative reconstruction methods.LEVEL OF EVIDENCE: Level IV, therapeutic study.PMID:38666740 | DOI:10.1097/CORR.0000000000003097 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 26, 2024 Category: Orthopaedics Authors: Arman Vahabi H üseyin Kaya Hakan Koray Tosyal ı Bur çin Keçeci D ündar Sabah Source Type: research

Contralateral Neck-shaft Angle Lower Than 130 ° Is Associated With Clinical Failure in Nongeriatric Individuals: Analysis of the National Femoral Neck Fracture Database of 1066 Patients
CONCLUSION: In our study of screw fixations for femoral neck fractures among nongeriatric patients, we identified that a contralateral NSA < 130° correlates with an increased risk of clinical failure including nonunion, AVN, functional failure, and reoperation. The effect is either direct or mediated through displaced fracture types. This is important for surgeons in order to recognize the elevated rate of clinical failure and nature of the challenging biomechanical environment, which should guide them in refining surgical details and selecting appropriate fixation and rehabilitation plans. Approaches to managing these...
Source: Clinical Orthopaedics and Related Research - April 25, 2024 Category: Orthopaedics Authors: Dajun Jiang Hongyi Zhu Jiaqing Cao Qianying Cai Feng Wu Xiaolin Li Kaifu Wang Weitao Jia Source Type: research

CORR Insights ®: Health Disparities in Patients With Musculoskeletal Injuries: Food Insecurity Is a Common and Clinically Challenging Problem
Clin Orthop Relat Res. 2024 Apr 18. doi: 10.1097/CORR.0000000000003089. Online ahead of print.NO ABSTRACTPMID:38662921 | DOI:10.1097/CORR.0000000000003089 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 25, 2024 Category: Orthopaedics Authors: Jeffrey Okewunmi Source Type: research

CORR Insights ®: Is Limited English Proficiency Associated With Differences in Care Processes and Treatment Outcomes in Patients Undergoing Orthopaedic Surgery? A Systematic Review
Clin Orthop Relat Res. 2024 Apr 18. doi: 10.1097/CORR.0000000000003085. Online ahead of print.NO ABSTRACTPMID:38662922 | DOI:10.1097/CORR.0000000000003085 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 25, 2024 Category: Orthopaedics Authors: Ronald A Navarro Source Type: research

Chondrocyte Invasion May Be a Mechanism for Persistent Staphylococcus Aureus Infection In Vitro
CONCLUSION: S. aureus readily invaded human chondrocytes (C20A4) in vitro and persisted viably for 6 days after infection, evading extracellular antibiotics. Chondrocytes demonstrated a greater level of intracellular invasion and persistence by S. aureus than positive control human osteoblast (MG63) and mouse fibroblast (NIH3T3) cell lines.CLINICAL RELEVANCE: Chondrocyte invasion and persistence may contribute to recurrent bone and joint infections. Additional research should assess longer periods of persistence and whether this mechanism is present in vivo.PMID:38662927 | DOI:10.1097/CORR.0000000000003074 (Source: Clinica...
Source: Clinical Orthopaedics and Related Research - April 25, 2024 Category: Orthopaedics Authors: Jerry Chang David Kerr Megan Zheng Thorsten Seyler Source Type: research

Human Infrapatellar Fat Pad Mesenchymal Stem Cell-derived Extracellular Vesicles Purified by Anion Exchange Chromatography Suppress Osteoarthritis Progression in a Mouse Model
CONCLUSION: Using an OA mouse model, we found that infrapatellar fat pad-derived MSC-extracellular vesicles could delay OA progression via alleviating pain and suppressing cartilage degeneration, osteophyte formation, and synovial inflammation. The autologous origin of extracellular vesicles and scalable purification method make our strategy potentially viable for clinical translation.CLINICAL RELEVANCE: Infrapatellar fat pad-derived MSC-extracellular vesicles isolated by anion exchange chromatography can suppress OA progression in a mouse model. Further studies with large-animal models, larger animal groups, and subsequen...
Source: Clinical Orthopaedics and Related Research - April 25, 2024 Category: Orthopaedics Authors: Qisong Liu Jianqun Wu Hua Wang Zhaofeng Jia Guangheng Li Source Type: research

Static Versus Articulating Spacer: Does Infectious Pathogen Type Affect Treatment Success?
CONCLUSION: The lack of a difference in failure-free survival and insufficient evidence of a difference in the association between spacer type and treatment failure by pathogen type suggests that infectious organism may not be an important consideration in the decision about spacer treatment type. Further studies should aim to elucidate which patient factors are the most influential in surgeon decision-making when choosing a spacer type in patients with PJI of the knee.Level of Evidence Level III, therapeutic study.PMID:38662933 | DOI:10.1097/CORR.0000000000003075 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 25, 2024 Category: Orthopaedics Authors: Caitlin Grant Jerry Chang Emily Poehlein Cynthia L Green Jessica Seidelman William Jiranek Source Type: research

Very Few ACGME-accredited Orthopaedic Surgery Residency Programs Have Web-accessible Leave Policies Dedicated to Parental Leave for Residents, Despite ACGME Requirements
CONCLUSION: Although most ACGME-accredited allopathic orthopaedic surgery residency programs met the ACGME requirement of written parental leave policies in 2023, a small minority of programs have clear, accessible parental leave policies provided on their webpage.CLINICAL RELEVANCE: Parental leave policies should be easily accessible to prospective and current trainees and should clearly state compensation and length of leave. Ensuring orthopaedic surgery residency programs provide accessible and transparent parental leave policies is important for maintaining diversity in prospective applicants and supporting the work-li...
Source: Clinical Orthopaedics and Related Research - April 25, 2024 Category: Orthopaedics Authors: Angela M Mercurio Olivia L Lynch Beth E Shubin Stein Elizabeth G Matzkin Jo A Hannafin Dawn LaPorte Brittany M Ammerman Source Type: research

On Patient Safety: The Danger of Private Equity Involvement in Healthcare
Clin Orthop Relat Res. 2024 Apr 24. doi: 10.1097/CORR.0000000000003096. Online ahead of print.NO ABSTRACTPMID:38662944 | DOI:10.1097/CORR.0000000000003096 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 25, 2024 Category: Orthopaedics Authors: James Rickert Source Type: research

CORR Insights ®: Do Women and Minority Orthopaedic Residents Report Experiencing Worse Well-being and More Mistreatment Than Their Peers?
Clin Orthop Relat Res. 2024 Apr 11. doi: 10.1097/CORR.0000000000003061. Online ahead of print.NO ABSTRACTPMID:38629630 | DOI:10.1097/CORR.0000000000003061 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 17, 2024 Category: Orthopaedics Authors: Amanda Mener Source Type: research

CORR Insights ®: Do Women and Minority Orthopaedic Residents Report Experiencing Worse Well-being and More Mistreatment Than Their Peers?
Clin Orthop Relat Res. 2024 Apr 11. doi: 10.1097/CORR.0000000000003061. Online ahead of print.NO ABSTRACTPMID:38629630 | DOI:10.1097/CORR.0000000000003061 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 17, 2024 Category: Orthopaedics Authors: Amanda Mener Source Type: research

CORR Insights ®: Do Women and Minority Orthopaedic Residents Report Experiencing Worse Well-being and More Mistreatment Than Their Peers?
Clin Orthop Relat Res. 2024 Apr 11. doi: 10.1097/CORR.0000000000003061. Online ahead of print.NO ABSTRACTPMID:38629630 | DOI:10.1097/CORR.0000000000003061 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 17, 2024 Category: Orthopaedics Authors: Amanda Mener Source Type: research

CORR Insights ®: Do Women and Minority Orthopaedic Residents Report Experiencing Worse Well-being and More Mistreatment Than Their Peers?
Clin Orthop Relat Res. 2024 Apr 11. doi: 10.1097/CORR.0000000000003061. Online ahead of print.NO ABSTRACTPMID:38629630 | DOI:10.1097/CORR.0000000000003061 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 17, 2024 Category: Orthopaedics Authors: Amanda Mener Source Type: research

Erratum to: Are Fibular Allograft Struts Useful for Unicameral Bone Cysts of the Proximal Humerus in Skeletally Mature Patients?
Clin Orthop Relat Res. 2024 Apr 9;482(5):907. doi: 10.1097/CORR.0000000000003064. Online ahead of print.NO ABSTRACTPMID:38595142 | PMC:PMC11008665 | DOI:10.1097/CORR.0000000000003064 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 10, 2024 Category: Orthopaedics Authors: Khodamorad Jamshidi Mehrdad Bahradadi Marjan Bahrabadi Alireza Mirzaei Source Type: research

Erratum to: Are Fibular Allograft Struts Useful for Unicameral Bone Cysts of the Proximal Humerus in Skeletally Mature Patients?
Clin Orthop Relat Res. 2024 Apr 9;482(5):907. doi: 10.1097/CORR.0000000000003064. Online ahead of print.NO ABSTRACTPMID:38595142 | PMC:PMC11008665 | DOI:10.1097/CORR.0000000000003064 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 10, 2024 Category: Orthopaedics Authors: Khodamorad Jamshidi Mehrdad Bahradadi Marjan Bahrabadi Alireza Mirzaei Source Type: research