Analytical and Bioanalytical Methods for the Determination of Dipeptidyl Peptidase-4 Inhibitors in Various Matrices: A Comprehensive Review
CONCLUSION: The comprehensive assessment of methods for analysing DPP-4 inhibitors can be a valuable resource for researchers and healthcare practitioners. Hitherto, no review encompassing all DPP-4 inhibitors has been presented. Therefore, gaps in the data available on a particular subject, need to be required to collect data on a particular construct. The review suggests that chromatographic techniques were majorly used for analysis wherein solvents like acetonitrile, methanol, and buffer solutions were used as mobile phases that can deteriorate HPLC columns and equipment. So, scientists could investigate new methods for...
Source: Current Diabetes Reviews - May 6, 2024 Category: Endocrinology Authors: Sakshi Hadawale Sanjay Sharma Source Type: research
Therapeutic Interventions for Diabetes Mellitus-Associated Complications
CONCLUSION: This review has emphasized the need for an improved understanding of these advancements, which is essential to enhance clinicians' ability to identify the most effective therapeutic interventions.PMID:38706367 | DOI:10.2174/0115733998291870240408043837 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - May 6, 2024 Category: Endocrinology Authors: Dharmendra Pradhan Prafulla Kumar Sahu Sukumar Purohit Santosh Kumar Ranajit Biswajeet Acharya Shreya Sangam Amit Kumar Shrivastava Source Type: research
Impaired Fibroblast Growth Factor 21 (FGF21) Associated with Visceral Adiposity Leads to Insulin Resistance: The Core Defect in Diabetes Mellitus
Curr Diabetes Rev. 2024 Apr 26. doi: 10.2174/0115733998265915231116043813. Online ahead of print.ABSTRACTThe Central nervous system (CNS) is the prime regulator of signaling pathways whose function includes regulation of food intake (consumption), energy expenditure, and other metabolic responses like glycolysis, gluconeogenesis, fatty acid oxidation, and thermogenesis that have been implicated in chronic inflammatory disorders. Type 2 diabetes mellitus (T2DM) and obesity are two metabolic disorders that are linked together and have become an epidemic worldwide, thus raising significant public health concerns. Fibroblast g...
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Unnati Jain Priyanka Srivastava Ashwani Sharma Subrata Sinha Surabhi Johari Source Type: research
Phloridzin's Diabetic Wound Healing Potential through DPP-4 Enzyme Inhibition: A Review Article
This study offers new research directions for examining phloridzin's capacity to withstand oxidative stress, as well as for redefining its tactical function as a powerful DPP-4 inhibitor to regulate the process involved in the healing of diabetic wounds.PMID:38676506 | DOI:10.2174/0115733998291941240416053855 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Khushi Sharma Vadivelan Ramachandran Ashutosh Sharma Tharani Mohanasundaram Harshini Mageshkumar Source Type: research
A Scoping Review of GIS Mapping of Type 1 Diabetes in Children: Identifying Current Gaps and Future Research Directions Using PRISMA-ScR
CONCLUSION: Studies on type 1 diabetes highlight the complex relationship between incidence and risk, suggesting comprehensive prevention and treatment. Geographical mapping has potential in low- and middle-income nations, but further research is needed to develop innovative strategies. The importance of geomappping in understanding the risk factors for Type 1 Diabetes is highlighted in this scoping review, which also suggests a possible direction for focused interventions, particularly in settings with low resources.PMID:38676507 | DOI:10.2174/0115733998288125240402052930 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Demi Miriam Navendu Chaudhary Sushil Yewale Anuradha Khadilkar Source Type: research
Technology for the Management of Type 1 Diabetes Mellitus in Saudi Arabia and MENA Region: A Systematic Review
CONCLUSION: There was a positive impact of insulin pumps, continuous glucose monitoring (CGM) systems, and telemedicine in achieving optimal glucose control and better QoL. Further studies are recommended to clarify the significant role of advanced diabetes technologies.PMID:38676508 | DOI:10.2174/0115733998295755240416060913 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Ayman Al Hayek Mohamed A Al Dawish Source Type: research
Probiotic Supplementation during Pregnancy: Evaluating the Current Clinical Evidence Against Gestational Diabetes Mellitus
CONCLUSION: Probiotic supplementation at conventional dosages and in combination with a balanced healthy diet, and lifestyle seems to reduce the the risk of developing GDM, while ameliorating the severity of its symptoms. Further clinical studies taking into account the above considerations should be performed to establish conclusive results, while the future meta-analyses should include studies with the feasibly lowest heterogeneity.PMID:38676509 | DOI:10.2174/0115733998284749240417052006 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Eleni Pavlidou Olga Alexatou Gerasimos Tsourouflis Georgios Antasouras Sousana K Papadopoulou Dimitrios Papandreou Anastasia Sampani Constantinos Giaginis Source Type: research
Impaired Fibroblast Growth Factor 21 (FGF21) Associated with Visceral Adiposity Leads to Insulin Resistance: The Core Defect in Diabetes Mellitus
Curr Diabetes Rev. 2024 Apr 26. doi: 10.2174/0115733998265915231116043813. Online ahead of print.ABSTRACTThe Central nervous system (CNS) is the prime regulator of signaling pathways whose function includes regulation of food intake (consumption), energy expenditure, and other metabolic responses like glycolysis, gluconeogenesis, fatty acid oxidation, and thermogenesis that have been implicated in chronic inflammatory disorders. Type 2 diabetes mellitus (T2DM) and obesity are two metabolic disorders that are linked together and have become an epidemic worldwide, thus raising significant public health concerns. Fibroblast g...
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Unnati Jain Priyanka Srivastava Ashwani Sharma Subrata Sinha Surabhi Johari Source Type: research
Phloridzin's Diabetic Wound Healing Potential through DPP-4 Enzyme Inhibition: A Review Article
This study offers new research directions for examining phloridzin's capacity to withstand oxidative stress, as well as for redefining its tactical function as a powerful DPP-4 inhibitor to regulate the process involved in the healing of diabetic wounds.PMID:38676506 | DOI:10.2174/0115733998291941240416053855 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Khushi Sharma Vadivelan Ramachandran Ashutosh Sharma Tharani Mohanasundaram Harshini Mageshkumar Source Type: research
A Scoping Review of GIS Mapping of Type 1 Diabetes in Children: Identifying Current Gaps and Future Research Directions Using PRISMA-ScR
CONCLUSION: Studies on type 1 diabetes highlight the complex relationship between incidence and risk, suggesting comprehensive prevention and treatment. Geographical mapping has potential in low- and middle-income nations, but further research is needed to develop innovative strategies. The importance of geomappping in understanding the risk factors for Type 1 Diabetes is highlighted in this scoping review, which also suggests a possible direction for focused interventions, particularly in settings with low resources.PMID:38676507 | DOI:10.2174/0115733998288125240402052930 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Demi Miriam Navendu Chaudhary Sushil Yewale Anuradha Khadilkar Source Type: research
Technology for the Management of Type 1 Diabetes Mellitus in Saudi Arabia and MENA Region: A Systematic Review
CONCLUSION: There was a positive impact of insulin pumps, continuous glucose monitoring (CGM) systems, and telemedicine in achieving optimal glucose control and better QoL. Further studies are recommended to clarify the significant role of advanced diabetes technologies.PMID:38676508 | DOI:10.2174/0115733998295755240416060913 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Ayman Al Hayek Mohamed A Al Dawish Source Type: research
Probiotic Supplementation during Pregnancy: Evaluating the Current Clinical Evidence Against Gestational Diabetes Mellitus
CONCLUSION: Probiotic supplementation at conventional dosages and in combination with a balanced healthy diet, and lifestyle seems to reduce the the risk of developing GDM, while ameliorating the severity of its symptoms. Further clinical studies taking into account the above considerations should be performed to establish conclusive results, while the future meta-analyses should include studies with the feasibly lowest heterogeneity.PMID:38676509 | DOI:10.2174/0115733998284749240417052006 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Eleni Pavlidou Olga Alexatou Gerasimos Tsourouflis Georgios Antasouras Sousana K Papadopoulou Dimitrios Papandreou Anastasia Sampani Constantinos Giaginis Source Type: research
Impaired Fibroblast Growth Factor 21 (FGF21) Associated with Visceral Adiposity Leads to Insulin Resistance: The Core Defect in Diabetes Mellitus
Curr Diabetes Rev. 2024 Apr 26. doi: 10.2174/0115733998265915231116043813. Online ahead of print.ABSTRACTThe Central nervous system (CNS) is the prime regulator of signaling pathways whose function includes regulation of food intake (consumption), energy expenditure, and other metabolic responses like glycolysis, gluconeogenesis, fatty acid oxidation, and thermogenesis that have been implicated in chronic inflammatory disorders. Type 2 diabetes mellitus (T2DM) and obesity are two metabolic disorders that are linked together and have become an epidemic worldwide, thus raising significant public health concerns. Fibroblast g...
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Unnati Jain Priyanka Srivastava Ashwani Sharma Subrata Sinha Surabhi Johari Source Type: research
Phloridzin's Diabetic Wound Healing Potential through DPP-4 Enzyme Inhibition: A Review Article
This study offers new research directions for examining phloridzin's capacity to withstand oxidative stress, as well as for redefining its tactical function as a powerful DPP-4 inhibitor to regulate the process involved in the healing of diabetic wounds.PMID:38676506 | DOI:10.2174/0115733998291941240416053855 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Khushi Sharma Vadivelan Ramachandran Ashutosh Sharma Tharani Mohanasundaram Harshini Mageshkumar Source Type: research
A Scoping Review of GIS Mapping of Type 1 Diabetes in Children: Identifying Current Gaps and Future Research Directions Using PRISMA-ScR
CONCLUSION: Studies on type 1 diabetes highlight the complex relationship between incidence and risk, suggesting comprehensive prevention and treatment. Geographical mapping has potential in low- and middle-income nations, but further research is needed to develop innovative strategies. The importance of geomappping in understanding the risk factors for Type 1 Diabetes is highlighted in this scoping review, which also suggests a possible direction for focused interventions, particularly in settings with low resources.PMID:38676507 | DOI:10.2174/0115733998288125240402052930 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Demi Miriam Navendu Chaudhary Sushil Yewale Anuradha Khadilkar Source Type: research
