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Levetiracetam Induced Behavioural Changes in an Adult Female Patient: A Case Report
CONCLUSION: Consequently, the drug was discontinued, resulting in the resolution of the behavioural symptoms. This case highlights levetiracetam as the likely causative factor behind the observed significant behavioural changes.PMID:38584560 | DOI:10.2174/0115748863285429240326172920 (Source: Current Drug Safety)
Source: Current Drug Safety - April 8, 2024 Category: Drugs & Pharmacology Authors: Hemangi Amrutbhai Virani Hetal Kantilal Dabhi Piyushkumar Mansinh Pargi Source Type: research

Dopaminergic Drugs and Valproate-associated Refractory Hyponatremia Over Levosulpiride-induced Parkinsonism in an Elderly Female Patient When Deprescribing was the Only Therapy
CONCLUSION: The case highlights the need to be vigilant for adverse consequences of the prescribing cascade, especially for antiemetic drugs, such as levosulpiride, because of its propensity to induce extrapyramidal reactions in older patients. In cases of refractory hyponatremia, a trial of de-challenge of valproate and dopaminergic drugs should be considered. The identification and removal of the culprit drugs can rescue the patient from a disabling cycle of adverse drug reactions.PMID:38523545 | DOI:10.2174/0115748863288106240313042127 (Source: Current Drug Safety)
Source: Current Drug Safety - March 25, 2024 Category: Drugs & Pharmacology Authors: Amol Dehade Sankha Shubhra Chakrabarti Noti Taruni Srija Reddy Upinder Kaur Source Type: research

Dopaminergic Drugs and Valproate-associated Refractory Hyponatremia Over Levosulpiride-induced Parkinsonism in an Elderly Female Patient When Deprescribing was the Only Therapy
CONCLUSION: The case highlights the need to be vigilant for adverse consequences of the prescribing cascade, especially for antiemetic drugs, such as levosulpiride, because of its propensity to induce extrapyramidal reactions in older patients. In cases of refractory hyponatremia, a trial of de-challenge of valproate and dopaminergic drugs should be considered. In addition, the identification and removal of the culprit drugs can rescue the patient from a disabling cycle of adverse drug reactions.PMID:38523545 | DOI:10.2174/0115748863288106240313042127 (Source: Current Drug Safety)
Source: Current Drug Safety - March 25, 2024 Category: Drugs & Pharmacology Authors: Amol Dehade Sankha Shubhra Chakrabarti Not Taruni Srija Reddy Upinder Kaur Source Type: research