Automated Measurement and Three-Dimensional Fitting of Corneal Ulcerations and Erosions via AI-Based Image Analysis
CONCLUSIONS: The developed algorithm is capable of reliably providing exact values for corneal lesion sizes. Additionally, three-dimensional modeling of the corneal surface is essential for an accurate measurement of lesion sizes. Besides telemedicine applications, this approach harbors great potential for clinical trials where exact quantitative and observer-independent measurements are essential.PMID:38689527 | DOI:10.1080/02713683.2024.2344197 (Source: Current Eye Research)
Source: Current Eye Research - May 1, 2024 Category: Opthalmology Authors: David A Merle Astrid Heidinger Jutta Horwath-Winter Wolfgang List Heimo Bauer Michael Weissensteiner Patrick Kraus-F üreder Michael Mayrhofer-Reinhartshuber Philipp Kainz Gernot Steinwender Andreas Wedrich Source Type: research
Effect of Resveratrol on MMP-2 Expression in Scleral Fibroblasts: An < em > In Vitro < /em > Study
CONCLUSIONS: In conclusion, these findings suggest that Res increases COL1A1 expression while inhibiting MMP-2 and cell apoptosis in HFSFs, possibly through modulation of the JAK2/STAT3 signaling pathway.PMID:38679893 | DOI:10.1080/02713683.2024.2346940 (Source: Current Eye Research)
Source: Current Eye Research - April 29, 2024 Category: Opthalmology Authors: Xiaolan Tang Sha Lv Shichun Liu Shengfang Song Hua Li Source Type: research
Choriocapillaris Perfusion after 8 Weeks of High-Speed Circuit Training in Older Healthy Adults
CONCLUSION: CCD appeared to remain stable after 8 weeks of HSCT in healthy older individuals, possibly due to autoregulation. Further research with extended training may be necessary to verify these findings.PMID:38679899 | DOI:10.1080/02713683.2024.2346538 (Source: Current Eye Research)
Source: Current Eye Research - April 29, 2024 Category: Opthalmology Authors: Ava-Gaye Simms Joseph F Signorile Gustavo Rosa Gameiro Abdulrahman Mamoon Allaf Jianhua Wang Hong Jiang Source Type: research
Analyzing Tear Fluid Composition by Synchronous Fluorescence for Diagnosing Dry Eye Disease and the Role of Phytotherapy Intervention
CONCLUSION: There was change in the electrical conductivity of tear fluid proteins. In the case of dry eyes, they became electrical insulators, while in the case of treatment with extracts, their electrical conductivity properties improved. The effects of phytotherapy can be related to the high content of ellagic acid and anthocyanin of pomegranate extract, while in green tea, they are related to catechins and phenolic compounds.PMID:38679902 | DOI:10.1080/02713683.2024.2344184 (Source: Current Eye Research)
Source: Current Eye Research - April 29, 2024 Category: Opthalmology Authors: Shaimaa M Moussa Sherif S Mahmoud Eman M Aly Mona S Talaat Source Type: research
The Effect of Steroid Intervention before Vitrectomy for Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment: A Meta-Analysis and Systematic Review
CONCLUSION: Patients with rhegmatogenous retinal detachment associated with choroidal detachment who did not receive preoperative steroids achieved the same effect as patients with rhegmatogenous retinal detachment associated with choroidal detachment who did receive preoperative steroids in terms of retinal reattachment rate and visual acuity. It is recommended that patients with rhegmatogenous retinal detachment associated with choroidal detachment undergo surgery as promptly as possible.PMID:38679916 | DOI:10.1080/02713683.2024.2343333 (Source: Current Eye Research)
Source: Current Eye Research - April 29, 2024 Category: Opthalmology Authors: Pingping Li Lu Li Jianhua Wu Source Type: research
Effect of Resveratrol on MMP-2 Expression in Scleral Fibroblasts: An < em > In Vitro < /em > Study
CONCLUSIONS: In conclusion, these findings suggest that Res increases COL1A1 expression while inhibiting MMP-2 and cell apoptosis in HFSFs, possibly through modulation of the JAK2/STAT3 signaling pathway.PMID:38679893 | DOI:10.1080/02713683.2024.2346940 (Source: Current Eye Research)
Source: Current Eye Research - April 29, 2024 Category: Opthalmology Authors: Xiaolan Tang Sha Lv Shichun Liu Shengfang Song Hua Li Source Type: research
Choriocapillaris Perfusion after 8 Weeks of High-Speed Circuit Training in Older Healthy Adults
CONCLUSION: CCD appeared to remain stable after 8 weeks of HSCT in healthy older individuals, possibly due to autoregulation. Further research with extended training may be necessary to verify these findings.PMID:38679899 | DOI:10.1080/02713683.2024.2346538 (Source: Current Eye Research)
Source: Current Eye Research - April 29, 2024 Category: Opthalmology Authors: Ava-Gaye Simms Joseph F Signorile Gustavo Rosa Gameiro Abdulrahman Mamoon Allaf Jianhua Wang Hong Jiang Source Type: research
Analyzing Tear Fluid Composition by Synchronous Fluorescence for Diagnosing Dry Eye Disease and the Role of Phytotherapy Intervention
CONCLUSION: There was change in the electrical conductivity of tear fluid proteins. In the case of dry eyes, they became electrical insulators, while in the case of treatment with extracts, their electrical conductivity properties improved. The effects of phytotherapy can be related to the high content of ellagic acid and anthocyanin of pomegranate extract, while in green tea, they are related to catechins and phenolic compounds.PMID:38679902 | DOI:10.1080/02713683.2024.2344184 (Source: Current Eye Research)
Source: Current Eye Research - April 29, 2024 Category: Opthalmology Authors: Shaimaa M Moussa Sherif S Mahmoud Eman M Aly Mona S Talaat Source Type: research
The Effect of Steroid Intervention before Vitrectomy for Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment: A Meta-Analysis and Systematic Review
CONCLUSION: Patients with rhegmatogenous retinal detachment associated with choroidal detachment who did not receive preoperative steroids achieved the same effect as patients with rhegmatogenous retinal detachment associated with choroidal detachment who did receive preoperative steroids in terms of retinal reattachment rate and visual acuity. It is recommended that patients with rhegmatogenous retinal detachment associated with choroidal detachment undergo surgery as promptly as possible.PMID:38679916 | DOI:10.1080/02713683.2024.2343333 (Source: Current Eye Research)
Source: Current Eye Research - April 29, 2024 Category: Opthalmology Authors: Pingping Li Lu Li Jianhua Wu Source Type: research
Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals
CONCLUSIONS: This pilot study demonstrates that successful subretinal delivery of gene therapy vectors is achievable using a direct injection without prior vitrectomy surgery.PMID:38666493 | DOI:10.1080/02713683.2024.2343335 (Source: Current Eye Research)
Source: Current Eye Research - April 26, 2024 Category: Opthalmology Authors: Zbynek Stranak Taras Ardan Yaroslav Nemesh Maria Toms Lyes Toualbi Richard Harbottle Zdenka Ellederova Lyubomyr Lytvynchuk Goran Petrovski Jan Motlik Mariya Moosajee Igor Kozak Source Type: research
Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals
CONCLUSIONS: This pilot study demonstrates that successful subretinal delivery of gene therapy vectors is achievable using a direct injection without prior vitrectomy surgery.PMID:38666493 | DOI:10.1080/02713683.2024.2343335 (Source: Current Eye Research)
Source: Current Eye Research - April 26, 2024 Category: Opthalmology Authors: Zbynek Stranak Taras Ardan Yaroslav Nemesh Maria Toms Lyes Toualbi Richard Harbottle Zdenka Ellederova Lyubomyr Lytvynchuk Goran Petrovski Jan Motlik Mariya Moosajee Igor Kozak Source Type: research
Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals
CONCLUSIONS: This pilot study demonstrates that successful subretinal delivery of gene therapy vectors is achievable using a direct injection without prior vitrectomy surgery.PMID:38666493 | DOI:10.1080/02713683.2024.2343335 (Source: Current Eye Research)
Source: Current Eye Research - April 26, 2024 Category: Opthalmology Authors: Zbynek Stranak Taras Ardan Yaroslav Nemesh Maria Toms Lyes Toualbi Richard Harbottle Zdenka Ellederova Lyubomyr Lytvynchuk Goran Petrovski Jan Motlik Mariya Moosajee Igor Kozak Source Type: research
Role of Mesenchymal Stem Cell-Derived Conditioned Medium in Modulating the Benzalkonium Chloride-Induced Cytotoxic Effects in Cultured Corneal Epithelial Cells < em > In Vitro < /em >
CONCLUSIONS: Our results suggest that the MSC-CM is effective in modulating the BAK-induced cell death, retardation of metabolic activity and proliferation in cultured HCECs, particularly at lower concentration (0.001%) and shorter exposure (15 min) of BAK.PMID:38646923 | DOI:10.1080/02713683.2024.2342355 (Source: Current Eye Research)
Source: Current Eye Research - April 22, 2024 Category: Opthalmology Authors: Sreya Mitra Vasudeva Tati Sayan Basu Sachin Shukla Source Type: research
Rose Bengal Photodynamic Therapy (RB-PDT) Modulates the Inflammatory Response in LPS-Stimulated Human Corneal Fibroblasts By Influencing NF- κB and p38 MAPK Signaling Pathways
CONCLUSION: Rose bengal photodynamic therapy of lipopolysaccharide-stimulated human corneal fibroblasts can modify the inflammatory response by inducing interleukin-6 and interleukin-8 expression, and decreasing intercellular adhesion molecule-1 production. C-C motif chemokine ligand-4, interferon regulatory factor-3, and interferon α and β expressions are not affected by rose bengal photodynamic therapy in these cells. The underlying mechanisms may be associated with nuclear factor kappa B and p38 mitogen-activated protein kinase pathway activation.PMID:38646925 | DOI:10.1080/02713683.2024.2342600 (Source: Current Eye Research)
Source: Current Eye Research - April 22, 2024 Category: Opthalmology Authors: Ning Chai Tanja Stachon Tim Berger Zhen Li Maryam Amini Shweta Suiwal Berthold Seitz Achim Langenbucher N óra Szentmáry Source Type: research
Myopia and Rate of Peripapillary Retinal Nerve Fiber Layer Thickness in Diabetic Patients Without Retinopathy: A 2-Year Longitudinal Study
CONCLUSIONS: The diabetes group showed a faster rate of average pRNFL thickness reduction compared to healthy controls, regardless of the presence of myopia. The average pRNFL thickness decreased more rapidly when diabetes and myopia were present simultaneously than in the individual diabetes or myopia group. Both diabetes and myopia were associated with accelerated pRNFL loss.PMID:38647053 | DOI:10.1080/02713683.2024.2327087 (Source: Current Eye Research)
Source: Current Eye Research - April 22, 2024 Category: Opthalmology Authors: Yi Wu Kang Ning Mingguang He Wenyong Huang Wei Wang Source Type: research
