Heterologous DNA Prime/Protein Boost Immunization Targeting Nef-Tat Fusion Antigen Induces Potent T-cell Activity and in vitro Anti-SCR HIV-1 Effects
CONCLUSION: The chimeric HIV-1 Nef-Tat antigen was highly immunogenic, especially when applied in a heterologous prime/ boost regimen. This regimen could direct immune response toward cellular immunity (Th1 and CTL activity) and increase IFN-γ secretion after virus exposure.PMID:38712371 | DOI:10.2174/011570162X297602240430142231 (Source: Current HIV Research)
Source: Current HIV Research - May 7, 2024 Category: Infectious Diseases Authors: Leila Sadeghi Azam Bolhassani Elham Mohit Kazem Baesi Mohammad Reza Aghasadeghi Source Type: research
Assessment of Knowledge and Concern of People Living with HIV Regarding Human Mpox and Vaccination
CONCLUSION: The future study should focus on continuous education, promoting awareness through programs and establishing measures to successfully overcome identified variables that contribute to mpox pandemic understanding and attitudes. Applying the lessons learned from the COVID-19 pandemic will help the management of mpox virus.PMID:38698752 | DOI:10.2174/011570162X293673240427062123 (Source: Current HIV Research)
Source: Current HIV Research - May 3, 2024 Category: Infectious Diseases Authors: Deniz Borcak Yusuf Emre Özdemir Ye şilyurt Zuhal Esra Ensaro ğlu Samiha Akkaya Kadriye Kart Ya şar Source Type: research
Assessment of Knowledge and Concern of People Living with HIV Regarding Human Mpox and Vaccination
CONCLUSION: The future study should focus on continuous education, promoting awareness through programs and establishing measures to successfully overcome identified variables that contribute to mpox pandemic understanding and attitudes. Applying the lessons learned from the COVID-19 pandemic will help the management of mpox virus.PMID:38698752 | DOI:10.2174/011570162X293673240427062123 (Source: Current HIV Research)
Source: Current HIV Research - May 3, 2024 Category: Infectious Diseases Authors: Deniz Borcak Yusuf Emre Özdemir Ye şilyurt Zuhal Esra Ensaro ğlu Samiha Akkaya Kadriye Kart Ya şar Source Type: research
Assessment of Knowledge and Concern of People Living with HIV Regarding Human Mpox and Vaccination
CONCLUSION: The future study should focus on continuous education, promoting awareness through programs and establishing measures to successfully overcome identified variables that contribute to mpox pandemic understanding and attitudes. Applying the lessons learned from the COVID-19 pandemic will help the management of mpox virus.PMID:38698752 | DOI:10.2174/011570162X293673240427062123 (Source: Current HIV Research)
Source: Current HIV Research - May 3, 2024 Category: Infectious Diseases Authors: Deniz Borcak Yusuf Emre Özdemir Ye şilyurt Zuhal Esra Ensaro ğlu Samiha Akkaya Kadriye Kart Ya şar Source Type: research
Assessment of Knowledge and Concern of People Living with HIV Regarding Human Mpox and Vaccination
CONCLUSION: The future study should focus on continuous education, promoting awareness through programs and establishing measures to successfully overcome identified variables that contribute to mpox pandemic understanding and attitudes. Applying the lessons learned from the COVID-19 pandemic will help the management of mpox virus.PMID:38698752 | DOI:10.2174/011570162X293673240427062123 (Source: Current HIV Research)
Source: Current HIV Research - May 3, 2024 Category: Infectious Diseases Authors: Deniz Borcak Yusuf Emre Özdemir Ye şilyurt Zuhal Esra Ensaro ğlu Samiha Akkaya Kadriye Kart Ya şar Source Type: research
Outcomes of Total Hip Arthroplasty Performed for HIV-Associated Osteonecrosis in China: A Retrospective Cohort Study
CONCLUSION: THA is safe and effective in Chinese AIDS patients with ONFH. However, optimal treatment has limited efficacy in AIDS patients undergoing THA for ONFH. The reconsideration and evaluation of the predictive value of CD4+ T lymphocytes for postoperative complications in joint replacement procedures is warranted.PMID:38638043 | DOI:10.2174/011570162X302889240408033958 (Source: Current HIV Research)
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Kangpeng Li Rui Ma Rugang Zhao Qiang Zhang Source Type: research
The Hidden Enemy Within: Uncovering the Secrets of HIV Tissues Reservoirs and Current mRNA Vaccine Development
Curr HIV Res. 2024 Apr 18. doi: 10.2174/011570162X301593240409072840. Online ahead of print.ABSTRACTHuman Immunodeficiency Viruses (HIV) continue to pose a significant global health threat despite the availability of antiretroviral therapy (ART). As a retrovirus, HIV persists as a stable, integrated, and replication-competent provirus within a diverse array of long-lived cells for many years, often termed "latent reservoirs" in individuals. Thus, this review aims to furnish a comprehensive overview of diverse tissue reservoirs where HIV persists, elucidating their pathogenesis and advancement in their strategies for clinic...
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Satyendra Prakash Mayank Kumar Source Type: research
Outcomes of Total Hip Arthroplasty Performed for HIV-Associated Osteonecrosis in China: A Retrospective Cohort Study
CONCLUSION: THA is safe and effective in Chinese AIDS patients with ONFH. However, optimal treatment has limited efficacy in AIDS patients undergoing THA for ONFH. The reconsideration and evaluation of the predictive value of CD4+ T lymphocytes for postoperative complications in joint replacement procedures is warranted.PMID:38638043 | DOI:10.2174/011570162X302889240408033958 (Source: Current HIV Research)
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Kangpeng Li Rui Ma Rugang Zhao Qiang Zhang Source Type: research
The Hidden Enemy Within: Uncovering the Secrets of HIV Tissues Reservoirs and Current mRNA Vaccine Development
Curr HIV Res. 2024 Apr 18. doi: 10.2174/011570162X301593240409072840. Online ahead of print.ABSTRACTHuman Immunodeficiency Viruses (HIV) continue to pose a significant global health threat despite the availability of antiretroviral therapy (ART). As a retrovirus, HIV persists as a stable, integrated, and replication-competent provirus within a diverse array of long-lived cells for many years, often termed "latent reservoirs" in individuals. Thus, this review aims to furnish a comprehensive overview of diverse tissue reservoirs where HIV persists, elucidating their pathogenesis and advancement in their strategies for clinic...
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Satyendra Prakash Mayank Kumar Source Type: research
Outcomes of Total Hip Arthroplasty Performed for HIV-Associated Osteonecrosis in China: A Retrospective Cohort Study
CONCLUSION: THA is safe and effective in Chinese AIDS patients with ONFH. However, optimal treatment has limited efficacy in AIDS patients undergoing THA for ONFH. The reconsideration and evaluation of the predictive value of CD4+ T lymphocytes for postoperative complications in joint replacement procedures is warranted.PMID:38638043 | DOI:10.2174/011570162X302889240408033958 (Source: Current HIV Research)
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Kangpeng Li Rui Ma Rugang Zhao Qiang Zhang Source Type: research
The Hidden Enemy Within: Uncovering the Secrets of HIV Tissues Reservoirs and Current mRNA Vaccine Development
Curr HIV Res. 2024 Apr 18. doi: 10.2174/011570162X301593240409072840. Online ahead of print.ABSTRACTHuman Immunodeficiency Viruses (HIV) continue to pose a significant global health threat despite the availability of antiretroviral therapy (ART). As a retrovirus, HIV persists as a stable, integrated, and replication-competent provirus within a diverse array of long-lived cells for many years, often termed "latent reservoirs" in individuals. Thus, this review aims to furnish a comprehensive overview of diverse tissue reservoirs where HIV persists, elucidating their pathogenesis and advancement in their strategies for clinic...
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Satyendra Prakash Mayank Kumar Source Type: research
Outcomes of Total Hip Arthroplasty Performed for HIV-Associated Osteonecrosis in China: A Retrospective Cohort Study
CONCLUSION: THA is safe and effective in Chinese AIDS patients with ONFH. However, optimal treatment has limited efficacy in AIDS patients undergoing THA for ONFH. The reconsideration and evaluation of the predictive value of CD4+ T lymphocytes for postoperative complications in joint replacement procedures is warranted.PMID:38638043 | DOI:10.2174/011570162X302889240408033958 (Source: Current HIV Research)
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Kangpeng Li Rui Ma Rugang Zhao Qiang Zhang Source Type: research
The Hidden Enemy Within: Uncovering the Secrets of HIV Tissues Reservoirs and Current mRNA Vaccine Development
Curr HIV Res. 2024 Apr 18. doi: 10.2174/011570162X301593240409072840. Online ahead of print.ABSTRACTHuman Immunodeficiency Viruses (HIV) continue to pose a significant global health threat despite the availability of antiretroviral therapy (ART). As a retrovirus, HIV persists as a stable, integrated, and replication-competent provirus within a diverse array of long-lived cells for many years, often termed "latent reservoirs" in individuals. Thus, this review aims to furnish a comprehensive overview of diverse tissue reservoirs where HIV persists, elucidating their pathogenesis and advancement in their strategies for clinic...
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Satyendra Prakash Mayank Kumar Source Type: research
Outcomes of Total Hip Arthroplasty Performed for HIV-Associated Osteonecrosis in China: A Retrospective Cohort Study
CONCLUSION: THA is safe and effective in Chinese AIDS patients with ONFH. However, optimal treatment has limited efficacy in AIDS patients undergoing THA for ONFH. The reconsideration and evaluation of the predictive value of CD4+ T lymphocytes for postoperative complications in joint replacement procedures is warranted.PMID:38638043 | DOI:10.2174/011570162X302889240408033958 (Source: Current HIV Research)
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Kangpeng Li Rui Ma Rugang Zhao Qiang Zhang Source Type: research
The Hidden Enemy Within: Uncovering the Secrets of HIV Tissues Reservoirs and Current mRNA Vaccine Development
Curr HIV Res. 2024 Apr 18. doi: 10.2174/011570162X301593240409072840. Online ahead of print.ABSTRACTHuman Immunodeficiency Viruses (HIV) continue to pose a significant global health threat despite the availability of antiretroviral therapy (ART). As a retrovirus, HIV persists as a stable, integrated, and replication-competent provirus within a diverse array of long-lived cells for many years, often termed "latent reservoirs" in individuals. Thus, this review aims to furnish a comprehensive overview of diverse tissue reservoirs where HIV persists, elucidating their pathogenesis and advancement in their strategies for clinic...
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Satyendra Prakash Mayank Kumar Source Type: research
