Persistent chronic calcific pancreatitis with intraductal calculi associated with secondary diabetes mellitus type 3 and diabetic ketoacidosis - A case report
Endocr Regul. 2024 Apr 24;58(1):101-104. doi: 10.2478/enr-2024-0011. Print 2024 Jan 1.ABSTRACTDiabetes mellitus type 3 refers to diabetes secondary to an existing disease or condition of the exocrine pancreas and is an uncommon cause of diabetes occurring due to pancreatogenic pathology. It accounts for 15-20% of diabetic patients in Indian and Southeast Asian continents. This is case report of a rare case of type 3 diabetes mellitus (T3DM) presenting with diabetic ketoacidosis (DKA). The patient was admitted for DKA along with complaint of hyperglycemia, blood glucose of 405 mg/dl with HbA1c level of 13.7%. Computed tomog...
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Gurusha Bahl Dinesh K Upadhyay Madhumati Varma Rajveer Singh Subhankar Das Sadique Hussain Source Type: research
Inhibition of signaling protein ERN1 increases the sensitivity of serine synthesis gene expressions to glucose and glutamine deprivations in U87MG glioblastoma cells
Conclusion. Taken together, the results of present study indicate that the expression of genes responsible for serine synthesis is sensitive to glucose and glutamine deprivations in gene-specific manner and that suppression of ERN1 signaling significantly modifies the impact of both glucose and glutamine deprivations on PHGDH, PSAT1, PSPH, ATF4, and SHMT1 gene expressions and reflects the ERN1-mediated genome reprograming introduced by nutrient deprivation condition.PMID:38656254 | DOI:10.2478/enr-2024-0010 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Oleksandr H Minchenko Myroslava Y Sliusar Olena O Khita Dmytro O Minchenko Yuliia M Viletska Oleh V Halkin Liudmyla O Levadna Anastasiia A Cherednychenko Yevgen P Khikhlo Source Type: research
Association of lipid profile and obesity in patients with polycystic ovary syndrome
Conclusion. The results showed that abnormal lipid profile and obesity have a significant association with PCOS patients. Regular monitoring and treatment of PCOS patients are required to reduce the risk of infertility, MetS, and CVD.PMID:38656255 | DOI:10.2478/enr-2024-0009 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Sadaf Parveen Saba Khan Mohammad Mustufa Khan Bhavana Gupta Ausaf Ahmad Roshan Alam Source Type: research
Oxytocin, GABA, and dopamine interplay in autism
Endocr Regul. 2024 Apr 24;58(1):105-114. doi: 10.2478/enr-2024-0012. Print 2024 Jan 1.ABSTRACTOxytocin plays an important role in brain development and is associated with various neurotransmitter systems in the brain. Abnormalities in the production, secretion, and distribution of oxytocin in the brain, at least during some stages of the development, are critical for the pathogenesis of neuropsychiatric diseases, particularly in the autism spectrum disorder. The etiology of autism includes changes in local sensory and dopaminergic areas of the brain, which are also supplied by the hypothalamic sources of oxytocin. It is ve...
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Tomas Havranek Zuzana Bacova Jan Bakos Source Type: research
Persistent chronic calcific pancreatitis with intraductal calculi associated with secondary diabetes mellitus type 3 and diabetic ketoacidosis - A case report
Endocr Regul. 2024 Apr 24;58(1):101-104. doi: 10.2478/enr-2024-0011. Print 2024 Jan 1.ABSTRACTDiabetes mellitus type 3 refers to diabetes secondary to an existing disease or condition of the exocrine pancreas and is an uncommon cause of diabetes occurring due to pancreatogenic pathology. It accounts for 15-20% of diabetic patients in Indian and Southeast Asian continents. This is case report of a rare case of type 3 diabetes mellitus (T3DM) presenting with diabetic ketoacidosis (DKA). The patient was admitted for DKA along with complaint of hyperglycemia, blood glucose of 405 mg/dl with HbA1c level of 13.7%. Computed tomog...
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Gurusha Bahl Dinesh K Upadhyay Madhumati Varma Rajveer Singh Subhankar Das Sadique Hussain Source Type: research
Inhibition of signaling protein ERN1 increases the sensitivity of serine synthesis gene expressions to glucose and glutamine deprivations in U87MG glioblastoma cells
Conclusion. Taken together, the results of present study indicate that the expression of genes responsible for serine synthesis is sensitive to glucose and glutamine deprivations in gene-specific manner and that suppression of ERN1 signaling significantly modifies the impact of both glucose and glutamine deprivations on PHGDH, PSAT1, PSPH, ATF4, and SHMT1 gene expressions and reflects the ERN1-mediated genome reprograming introduced by nutrient deprivation condition.PMID:38656254 | DOI:10.2478/enr-2024-0010 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Oleksandr H Minchenko Myroslava Y Sliusar Olena O Khita Dmytro O Minchenko Yuliia M Viletska Oleh V Halkin Liudmyla O Levadna Anastasiia A Cherednychenko Yevgen P Khikhlo Source Type: research
Association of lipid profile and obesity in patients with polycystic ovary syndrome
Conclusion. The results showed that abnormal lipid profile and obesity have a significant association with PCOS patients. Regular monitoring and treatment of PCOS patients are required to reduce the risk of infertility, MetS, and CVD.PMID:38656255 | DOI:10.2478/enr-2024-0009 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Sadaf Parveen Saba Khan Mohammad Mustufa Khan Bhavana Gupta Ausaf Ahmad Roshan Alam Source Type: research
Oxytocin, GABA, and dopamine interplay in autism
Endocr Regul. 2024 Apr 24;58(1):105-114. doi: 10.2478/enr-2024-0012. Print 2024 Jan 1.ABSTRACTOxytocin plays an important role in brain development and is associated with various neurotransmitter systems in the brain. Abnormalities in the production, secretion, and distribution of oxytocin in the brain, at least during some stages of the development, are critical for the pathogenesis of neuropsychiatric diseases, particularly in the autism spectrum disorder. The etiology of autism includes changes in local sensory and dopaminergic areas of the brain, which are also supplied by the hypothalamic sources of oxytocin. It is ve...
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Tomas Havranek Zuzana Bacova Jan Bakos Source Type: research
Persistent chronic calcific pancreatitis with intraductal calculi associated with secondary diabetes mellitus type 3 and diabetic ketoacidosis - A case report
Endocr Regul. 2024 Apr 24;58(1):101-104. doi: 10.2478/enr-2024-0011. Print 2024 Jan 1.ABSTRACTDiabetes mellitus type 3 refers to diabetes secondary to an existing disease or condition of the exocrine pancreas and is an uncommon cause of diabetes occurring due to pancreatogenic pathology. It accounts for 15-20% of diabetic patients in Indian and Southeast Asian continents. This is case report of a rare case of type 3 diabetes mellitus (T3DM) presenting with diabetic ketoacidosis (DKA). The patient was admitted for DKA along with complaint of hyperglycemia, blood glucose of 405 mg/dl with HbA1c level of 13.7%. Computed tomog...
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Gurusha Bahl Dinesh K Upadhyay Madhumati Varma Rajveer Singh Subhankar Das Sadique Hussain Source Type: research
Inhibition of signaling protein ERN1 increases the sensitivity of serine synthesis gene expressions to glucose and glutamine deprivations in U87MG glioblastoma cells
Conclusion. Taken together, the results of present study indicate that the expression of genes responsible for serine synthesis is sensitive to glucose and glutamine deprivations in gene-specific manner and that suppression of ERN1 signaling significantly modifies the impact of both glucose and glutamine deprivations on PHGDH, PSAT1, PSPH, ATF4, and SHMT1 gene expressions and reflects the ERN1-mediated genome reprograming introduced by nutrient deprivation condition.PMID:38656254 | DOI:10.2478/enr-2024-0010 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Oleksandr H Minchenko Myroslava Y Sliusar Olena O Khita Dmytro O Minchenko Yuliia M Viletska Oleh V Halkin Liudmyla O Levadna Anastasiia A Cherednychenko Yevgen P Khikhlo Source Type: research
Association of lipid profile and obesity in patients with polycystic ovary syndrome
Conclusion. The results showed that abnormal lipid profile and obesity have a significant association with PCOS patients. Regular monitoring and treatment of PCOS patients are required to reduce the risk of infertility, MetS, and CVD.PMID:38656255 | DOI:10.2478/enr-2024-0009 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Sadaf Parveen Saba Khan Mohammad Mustufa Khan Bhavana Gupta Ausaf Ahmad Roshan Alam Source Type: research
Oxytocin, GABA, and dopamine interplay in autism
Endocr Regul. 2024 Apr 24;58(1):105-114. doi: 10.2478/enr-2024-0012. Print 2024 Jan 1.ABSTRACTOxytocin plays an important role in brain development and is associated with various neurotransmitter systems in the brain. Abnormalities in the production, secretion, and distribution of oxytocin in the brain, at least during some stages of the development, are critical for the pathogenesis of neuropsychiatric diseases, particularly in the autism spectrum disorder. The etiology of autism includes changes in local sensory and dopaminergic areas of the brain, which are also supplied by the hypothalamic sources of oxytocin. It is ve...
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Tomas Havranek Zuzana Bacova Jan Bakos Source Type: research
Persistent chronic calcific pancreatitis with intraductal calculi associated with secondary diabetes mellitus type 3 and diabetic ketoacidosis - A case report
Endocr Regul. 2024 Apr 24;58(1):101-104. doi: 10.2478/enr-2024-0011. Print 2024 Jan 1.ABSTRACTDiabetes mellitus type 3 refers to diabetes secondary to an existing disease or condition of the exocrine pancreas and is an uncommon cause of diabetes occurring due to pancreatogenic pathology. It accounts for 15-20% of diabetic patients in Indian and Southeast Asian continents. This is case report of a rare case of type 3 diabetes mellitus (T3DM) presenting with diabetic ketoacidosis (DKA). The patient was admitted for DKA along with complaint of hyperglycemia, blood glucose of 405 mg/dl with HbA1c level of 13.7%. Computed tomog...
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Gurusha Bahl Dinesh K Upadhyay Madhumati Varma Rajveer Singh Subhankar Das Sadique Hussain Source Type: research
Inhibition of signaling protein ERN1 increases the sensitivity of serine synthesis gene expressions to glucose and glutamine deprivations in U87MG glioblastoma cells
Conclusion. Taken together, the results of present study indicate that the expression of genes responsible for serine synthesis is sensitive to glucose and glutamine deprivations in gene-specific manner and that suppression of ERN1 signaling significantly modifies the impact of both glucose and glutamine deprivations on PHGDH, PSAT1, PSPH, ATF4, and SHMT1 gene expressions and reflects the ERN1-mediated genome reprograming introduced by nutrient deprivation condition.PMID:38656254 | DOI:10.2478/enr-2024-0010 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Oleksandr H Minchenko Myroslava Y Sliusar Olena O Khita Dmytro O Minchenko Yuliia M Viletska Oleh V Halkin Liudmyla O Levadna Anastasiia A Cherednychenko Yevgen P Khikhlo Source Type: research
Association of lipid profile and obesity in patients with polycystic ovary syndrome
Conclusion. The results showed that abnormal lipid profile and obesity have a significant association with PCOS patients. Regular monitoring and treatment of PCOS patients are required to reduce the risk of infertility, MetS, and CVD.PMID:38656255 | DOI:10.2478/enr-2024-0009 (Source: Endocrine Regulations)
Source: Endocrine Regulations - April 24, 2024 Category: Endocrinology Authors: Sadaf Parveen Saba Khan Mohammad Mustufa Khan Bhavana Gupta Ausaf Ahmad Roshan Alam Source Type: research
