BMP4 in human endometrial stromal cells can affect decidualization by regulating FOXO1 expression
CONCLUSIONS: Our findings highlighted the downregulation of BMP4 in both RSA patients and mice. BMP4 in human endometrial stromal cells was shown to modulate decidualization by regulating FOXO1 expression. Loss of BMP4 may contribute to the pathogenesis of RSA, suggesting potential avenues for abortion prevention strategies.PMID:38679470 | DOI:10.1210/endocr/bqae049 (Source: Endocrinology)
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Yanjie Huang Fangfang Dai Liping Chen Zhidian Li Hua Liu Yanxiang Cheng Source Type: research
Glycoprotein-glycoprotein receptor binding detection using bioluminescence resonance energy transfer
Endocrinology. 2024 Apr 29:bqae052. doi: 10.1210/endocr/bqae052. Online ahead of print.ABSTRACTThe glycoprotein receptors, members of the large G protein-coupled receptors (GPCRs) family, are characterized by a large extracellular domains responsible of binding their glycoprotein hormones. Hormone-receptor interactions are traditionally analyzed by ligand-binding assays most often using radiolabeling but also by thermal shift assays. Despite their high sensitivity, these assays require appropriate laboratory conditions and, often, purified plasma cell membranes, which do not provide information on receptor localization or ...
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Kamila Adamczuk Thu Ha Ngo Jakub Czapinski Adolfo Rivero-M üller Source Type: research
BMP4 in human endometrial stromal cells can affect decidualization by regulating FOXO1 expression
CONCLUSIONS: Our findings highlighted the downregulation of BMP4 in both RSA patients and mice. BMP4 in human endometrial stromal cells was shown to modulate decidualization by regulating FOXO1 expression. Loss of BMP4 may contribute to the pathogenesis of RSA, suggesting potential avenues for abortion prevention strategies.PMID:38679470 | DOI:10.1210/endocr/bqae049 (Source: Endocrinology)
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Yanjie Huang Fangfang Dai Liping Chen Zhidian Li Hua Liu Yanxiang Cheng Source Type: research
Glycoprotein-glycoprotein receptor binding detection using bioluminescence resonance energy transfer
Endocrinology. 2024 Apr 29:bqae052. doi: 10.1210/endocr/bqae052. Online ahead of print.ABSTRACTThe glycoprotein receptors, members of the large G protein-coupled receptors (GPCRs) family, are characterized by a large extracellular domains responsible of binding their glycoprotein hormones. Hormone-receptor interactions are traditionally analyzed by ligand-binding assays most often using radiolabeling but also by thermal shift assays. Despite their high sensitivity, these assays require appropriate laboratory conditions and, often, purified plasma cell membranes, which do not provide information on receptor localization or ...
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Kamila Adamczuk Thu Ha Ngo Jakub Czapinski Adolfo Rivero-M üller Source Type: research
BMP4 in human endometrial stromal cells can affect decidualization by regulating FOXO1 expression
CONCLUSIONS: Our findings highlighted the downregulation of BMP4 in both RSA patients and mice. BMP4 in human endometrial stromal cells was shown to modulate decidualization by regulating FOXO1 expression. Loss of BMP4 may contribute to the pathogenesis of RSA, suggesting potential avenues for abortion prevention strategies.PMID:38679470 | DOI:10.1210/endocr/bqae049 (Source: Endocrinology)
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Yanjie Huang Fangfang Dai Liping Chen Zhidian Li Hua Liu Yanxiang Cheng Source Type: research
Glycoprotein-glycoprotein receptor binding detection using bioluminescence resonance energy transfer
Endocrinology. 2024 Apr 29:bqae052. doi: 10.1210/endocr/bqae052. Online ahead of print.ABSTRACTThe glycoprotein receptors, members of the large G protein-coupled receptors (GPCRs) family, are characterized by a large extracellular domains responsible of binding their glycoprotein hormones. Hormone-receptor interactions are traditionally analyzed by ligand-binding assays most often using radiolabeling but also by thermal shift assays. Despite their high sensitivity, these assays require appropriate laboratory conditions and, often, purified plasma cell membranes, which do not provide information on receptor localization or ...
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Kamila Adamczuk Thu Ha Ngo Jakub Czapinski Adolfo Rivero-M üller Source Type: research
BMP4 in human endometrial stromal cells can affect decidualization by regulating FOXO1 expression
CONCLUSIONS: Our findings highlighted the downregulation of BMP4 in both RSA patients and mice. BMP4 in human endometrial stromal cells was shown to modulate decidualization by regulating FOXO1 expression. Loss of BMP4 may contribute to the pathogenesis of RSA, suggesting potential avenues for abortion prevention strategies.PMID:38679470 | DOI:10.1210/endocr/bqae049 (Source: Endocrinology)
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Yanjie Huang Fangfang Dai Liping Chen Zhidian Li Hua Liu Yanxiang Cheng Source Type: research
Glycoprotein-glycoprotein receptor binding detection using bioluminescence resonance energy transfer
Endocrinology. 2024 Apr 29:bqae052. doi: 10.1210/endocr/bqae052. Online ahead of print.ABSTRACTThe glycoprotein receptors, members of the large G protein-coupled receptors (GPCRs) family, are characterized by a large extracellular domains responsible of binding their glycoprotein hormones. Hormone-receptor interactions are traditionally analyzed by ligand-binding assays most often using radiolabeling but also by thermal shift assays. Despite their high sensitivity, these assays require appropriate laboratory conditions and, often, purified plasma cell membranes, which do not provide information on receptor localization or ...
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Kamila Adamczuk Thu Ha Ngo Jakub Czapinski Adolfo Rivero-M üller Source Type: research
BMP4 in human endometrial stromal cells can affect decidualization by regulating FOXO1 expression
CONCLUSIONS: Our findings highlighted the downregulation of BMP4 in both RSA patients and mice. BMP4 in human endometrial stromal cells was shown to modulate decidualization by regulating FOXO1 expression. Loss of BMP4 may contribute to the pathogenesis of RSA, suggesting potential avenues for abortion prevention strategies.PMID:38679470 | DOI:10.1210/endocr/bqae049 (Source: Endocrinology)
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Yanjie Huang Fangfang Dai Liping Chen Zhidian Li Hua Liu Yanxiang Cheng Source Type: research
Glycoprotein-glycoprotein receptor binding detection using bioluminescence resonance energy transfer
Endocrinology. 2024 Apr 29:bqae052. doi: 10.1210/endocr/bqae052. Online ahead of print.ABSTRACTThe glycoprotein receptors, members of the large G protein-coupled receptors (GPCRs) family, are characterized by a large extracellular domains responsible of binding their glycoprotein hormones. Hormone-receptor interactions are traditionally analyzed by ligand-binding assays most often using radiolabeling but also by thermal shift assays. Despite their high sensitivity, these assays require appropriate laboratory conditions and, often, purified plasma cell membranes, which do not provide information on receptor localization or ...
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Kamila Adamczuk Thu Ha Ngo Jakub Czapinski Adolfo Rivero-M üller Source Type: research
BMP4 in human endometrial stromal cells can affect decidualization by regulating FOXO1 expression
CONCLUSIONS: Our findings highlighted the downregulation of BMP4 in both RSA patients and mice. BMP4 in human endometrial stromal cells was shown to modulate decidualization by regulating FOXO1 expression. Loss of BMP4 may contribute to the pathogenesis of RSA, suggesting potential avenues for abortion prevention strategies.PMID:38679470 | DOI:10.1210/endocr/bqae049 (Source: Endocrinology)
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Yanjie Huang Fangfang Dai Liping Chen Zhidian Li Hua Liu Yanxiang Cheng Source Type: research
Glycoprotein-glycoprotein receptor binding detection using bioluminescence resonance energy transfer
Endocrinology. 2024 Apr 29:bqae052. doi: 10.1210/endocr/bqae052. Online ahead of print.ABSTRACTThe glycoprotein receptors, members of the large G protein-coupled receptors (GPCRs) family, are characterized by a large extracellular domains responsible of binding their glycoprotein hormones. Hormone-receptor interactions are traditionally analyzed by ligand-binding assays most often using radiolabeling but also by thermal shift assays. Despite their high sensitivity, these assays require appropriate laboratory conditions and, often, purified plasma cell membranes, which do not provide information on receptor localization or ...
Source: Endocrinology - April 28, 2024 Category: Endocrinology Authors: Kamila Adamczuk Thu Ha Ngo Jakub Czapinski Adolfo Rivero-M üller Source Type: research
Correction to: "The Role of GLP-1 in the Metabolic Success of Bariatric Surgery"
Endocrinology. 2024 Mar 29;165(5):bqae042. doi: 10.1210/endocr/bqae042.NO ABSTRACTPMID:38651299 | DOI:10.1210/endocr/bqae042 (Source: Endocrinology)
Source: Endocrinology - April 23, 2024 Category: Endocrinology Source Type: research
Correction to: "The Role of GLP-1 in the Metabolic Success of Bariatric Surgery"
Endocrinology. 2024 Mar 29;165(5):bqae042. doi: 10.1210/endocr/bqae042.NO ABSTRACTPMID:38651299 | DOI:10.1210/endocr/bqae042 (Source: Endocrinology)
Source: Endocrinology - April 23, 2024 Category: Endocrinology Source Type: research
Correction to: "The Role of GLP-1 in the Metabolic Success of Bariatric Surgery"
Endocrinology. 2024 Mar 29;165(5):bqae042. doi: 10.1210/endocr/bqae042.NO ABSTRACTPMID:38651299 | DOI:10.1210/endocr/bqae042 (Source: Endocrinology)
Source: Endocrinology - April 23, 2024 Category: Endocrinology Source Type: research
