Environmental profiles, hazard identification, and toxicological hallmarks of emerging tire rubber-related contaminants 6PPD and 6PPD-quinone
Environ Int. 2024 Apr 21;187:108677. doi: 10.1016/j.envint.2024.108677. Online ahead of print.ABSTRACTN-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) is commonly used in rubber compounds as antioxidants to protect against degradation from heat, oxygen, and ozone exposure. This practice extends the lifespan of rubber products, including tires, by preventing cracking, aging, and deterioration. However, the environmental consequences of waste generated during rubber product use, particularly the formation of 6PPD-quinone (6PPD-Q) through the reaction of 6PPD with ozone, have raised significant concerns due to their ...
Source: Environment International - April 27, 2024 Category: Environmental Health Authors: Yang Jiang Chunzhi Wang Ling Ma Tiantian Gao Y án Wāng Source Type: research

Large walking and wellbeing behaviour benefits of co-designed sustainable park improvements: A natural experimental study in a UK deprived urban area
Environ Int. 2024 Apr 21;187:108669. doi: 10.1016/j.envint.2024.108669. Online ahead of print.ABSTRACTThere is little robust evidence of how sustainable park interventions impact on physical activity and other behaviours important for wellbeing. This controlled natural experimental study aimed to examine the effects of co-designing a sustainable park intervention, in a deprived UK urban area, on walking and other wellbeing behaviours. Behaviour observations were conducted at two intervention sites and two matched comparison sites (n = 4,783). Walking observations (primary outcome), wellbeing behaviours (vigorous, sedentary...
Source: Environment International - April 27, 2024 Category: Environmental Health Authors: Jamie Anderson Jack S Benton Junyan Ye Ellie Barker Vanessa G Macintyre Jack Wilkinson James Rothwell Matthew Dennis David P French Source Type: research

Aircraft noise exposure and body mass index among female participants in two Nurses' Health Study prospective cohorts living around 90 airports in the United States
This study investigates the association between aircraft noise and obesity among female participants in two prospective Nurses' Health Study (NHS and NHSII) cohorts.METHODS: Aircraft day-night average sound levels (DNL) were estimated at participant residential addresses from modeled 1 dB (dB) noise contours above 44 dB for 90 United States (U.S.) airports in 5-year intervals 1995-2010. Biennial surveys (1994-2017) provided information on body mass index (BMI; dichotomized, categorical) and other individual characteristics. Change in BMI from age 18 (BMI18; tertiles) was also calculated. Aircraft noise exposures were dicho...
Source: Environment International - April 27, 2024 Category: Environmental Health Authors: Matthew Bozigar Francine Laden Jaime E Hart Susan Redline Tianyi Huang Eric A Whitsel Elizabeth J Nelson Stephanie T Grady Jonathan I Levy Junenette L Peters Source Type: research

Prenatal exposure to air pollutant mixtures and birthweight in the upstate KIDS cohort
DISCUSSION: Prenatal exposure to air pollutants, notably PM2.5, during the final two weeks of pregnancy may negatively impact birthweight. The non-linear relationships between air pollution and birthweight highlight the importance of studying pollutant mixtures and their interactions.PMID:38677086 | DOI:10.1016/j.envint.2024.108692 (Source: Environment International)
Source: Environment International - April 27, 2024 Category: Environmental Health Authors: Ian R Trees Abhisek Saha Diane L Putnick Priscilla K Clayton Pauline Mendola Erin M Bell Rajeshwari Sundaram Edwina H Yeung Source Type: research

Letter to the editor
Environ Int. 2024 Apr 18;187:108665. doi: 10.1016/j.envint.2024.108665. Online ahead of print.ABSTRACTSome have looked forward to the publication of the results of the COSMOS study on brain tumors, because the potential biases from retrospective investigations predominating the search for brain tumor risks of mobile phone use since the late 1990 s were deemed unresolvable by further investigations of that type. Indeed, prospective cohort studies typically have the advantage of being not or less affected by differential exposure misclassification, recall and selection bias, and, as they proceed in the direction of the time ...
Source: Environment International - April 27, 2024 Category: Environmental Health Authors: Michael Kundi Source Type: research

Per- and polyfluoroalkyl substances induce lipid metabolic impairment in fish: Integration on field investigation and laboratory study
This study innovatively explored the adverse effects of PFOS and F-53B on lipid metabolism and their mechanisms at field and laboratory levels, highlighting concerns regarding PFASs health risks.PMID:38677088 | DOI:10.1016/j.envint.2024.108687 (Source: Environment International)
Source: Environment International - April 27, 2024 Category: Environmental Health Authors: Qiyu Wang Xueyan Gu Limin Mo Nannan Wan Liu Wu Shuai Liu Miao Zhang Mingqi Li Xi Liu Yu Liu Source Type: research

Assessing pesticides in the atmosphere: A global study on pollution, human health effects, monitoring network and regulatory performance
This study aimed to assess the extent of atmospheric pesticide pollution in countries worldwide and identify regional differences using a scoring approach. In addition to analyzing the health risks associated with pesticide pollution, we also examined agricultural practices and current air quality standards for pesticides in these countries. The pollution scores varied significantly among the countries, particularly in Europe. Asian and Oceanic countries generally had higher scores compared to those in the Americas, suggesting a relatively higher level of air pollution caused by pesticides in these regions. It is worth not...
Source: Environment International - April 26, 2024 Category: Environmental Health Authors: Yabi Huang Zijian Li Source Type: research

The research progress on the impact of antibiotics on the male reproductive system
Environ Int. 2024 Apr 24;187:108670. doi: 10.1016/j.envint.2024.108670. Online ahead of print.ABSTRACTAntibiotics are extensively utilized in the livestock and poultry industry and can accumulate in animals and the environment, leading to potential health risks for humans via food and water consumption. Research on antibiotic toxicity, particularly their impact as endocrine disruptors on the male reproductive system, is still in its nascent stages. This review highlights the toxic effect of antibiotics on the male reproductive system, detailing the common routes of exposure and the detrimental impact and mechanisms of vari...
Source: Environment International - April 26, 2024 Category: Environmental Health Authors: Lirui Hou Yuhan Fu Chong Zhao Lihong Fan Hongbo Hu Shutao Yin Source Type: research

Air quality on UK diesel and hybrid trains
Environ Int. 2024 Apr 20;187:108682. doi: 10.1016/j.envint.2024.108682. Online ahead of print.ABSTRACTConcentrations of particulate matter (PM10, PM2.5), ultrafine (UFP), particle number (PNC), black carbon (BC), nitrogen dioxide (NO2) and nitrogen oxides (NOX) were measured in train carriages on diesel and bi-mode trains on inter-city and long-distance journeys in the United Kingdom (UK) using a high-quality mobile measurement system. Air quality on 15 different routes was measured using highly-time resolved data on a total of 119 journeys during three campaigns in winter 2020 and summer 2021; this included 13 different t...
Source: Environment International - April 26, 2024 Category: Environmental Health Authors: Anna Font Michael Hedges Yiqun Han Shanon Lim Brendan Bos Anja H Tremper David C Green Source Type: research

Systematic investigation of organochlorine pesticides and polychlorinated biphenyls blood levels in Greek children from the Rhea birth cohort suggests historical exposure to DDT and through diet to DDE
Environ Int. 2024 Apr 23;187:108686. doi: 10.1016/j.envint.2024.108686. Online ahead of print.ABSTRACTThe blood levels of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) have been thoroughly investigated in Greek children from the Rhea birth cohort study. This investigation aimed to assess exposure levels, explore their possible relationship with children's age and sex, and indicate potential sources of exposure. Exposure patterns and common sources of PCBs and OCPs were analyzed using bivariate and multivariate statistics. A total of 947 blood samples from study participants were analyzed for OCP and...
Source: Environment International - April 26, 2024 Category: Environmental Health Authors: Danae Costopoulou Kleopatra Kedikoglou Marina Vafeiadi Theano Roumeliotaki Katerina Margetaki Euripides G Stephanou Antonis Myridakis Leondios Leondiadis Source Type: research

Corrigendum to "High-throughput screening of ancient forest plant extracts shows cytotoxicity towards triple-negative breast cancer" [Environ. Int. 181 (2023) 108279]
Environ Int. 2024 Apr 25:108695. doi: 10.1016/j.envint.2024.108695. Online ahead of print.NO ABSTRACTPMID:38670876 | DOI:10.1016/j.envint.2024.108695 (Source: Environment International)
Source: Environment International - April 26, 2024 Category: Environmental Health Authors: Yiyang Li Nyuk Ling Ma Huiling Chen Jiateng Zhong Dangquan Zhang Wanxi Peng Su Shiung Lam Yafeng Yang Xiaochen Yue Lijun Yan Ting Wang Bjarne Styrishave Tomasz Maciej Ciesielski Christian Sonne Source Type: research

Assessing pesticides in the atmosphere: A global study on pollution, human health effects, monitoring network and regulatory performance
This study aimed to assess the extent of atmospheric pesticide pollution in countries worldwide and identify regional differences using a scoring approach. In addition to analyzing the health risks associated with pesticide pollution, we also examined agricultural practices and current air quality standards for pesticides in these countries. The pollution scores varied significantly among the countries, particularly in Europe. Asian and Oceanic countries generally had higher scores compared to those in the Americas, suggesting a relatively higher level of air pollution caused by pesticides in these regions. It is worth not...
Source: Environment International - April 26, 2024 Category: Environmental Health Authors: Yabi Huang Zijian Li Source Type: research

The research progress on the impact of antibiotics on the male reproductive system
Environ Int. 2024 Apr 24;187:108670. doi: 10.1016/j.envint.2024.108670. Online ahead of print.ABSTRACTAntibiotics are extensively utilized in the livestock and poultry industry and can accumulate in animals and the environment, leading to potential health risks for humans via food and water consumption. Research on antibiotic toxicity, particularly their impact as endocrine disruptors on the male reproductive system, is still in its nascent stages. This review highlights the toxic effect of antibiotics on the male reproductive system, detailing the common routes of exposure and the detrimental impact and mechanisms of vari...
Source: Environment International - April 26, 2024 Category: Environmental Health Authors: Lirui Hou Yuhan Fu Chong Zhao Lihong Fan Hongbo Hu Shutao Yin Source Type: research

Air quality on UK diesel and hybrid trains
Environ Int. 2024 Apr 20;187:108682. doi: 10.1016/j.envint.2024.108682. Online ahead of print.ABSTRACTConcentrations of particulate matter (PM10, PM2.5), ultrafine (UFP), particle number (PNC), black carbon (BC), nitrogen dioxide (NO2) and nitrogen oxides (NOX) were measured in train carriages on diesel and bi-mode trains on inter-city and long-distance journeys in the United Kingdom (UK) using a high-quality mobile measurement system. Air quality on 15 different routes was measured using highly-time resolved data on a total of 119 journeys during three campaigns in winter 2020 and summer 2021; this included 13 different t...
Source: Environment International - April 26, 2024 Category: Environmental Health Authors: Anna Font Michael Hedges Yiqun Han Shanon Lim Brendan Bos Anja H Tremper David C Green Source Type: research

Systematic investigation of organochlorine pesticides and polychlorinated biphenyls blood levels in Greek children from the Rhea birth cohort suggests historical exposure to DDT and through diet to DDE
Environ Int. 2024 Apr 23;187:108686. doi: 10.1016/j.envint.2024.108686. Online ahead of print.ABSTRACTThe blood levels of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) have been thoroughly investigated in Greek children from the Rhea birth cohort study. This investigation aimed to assess exposure levels, explore their possible relationship with children's age and sex, and indicate potential sources of exposure. Exposure patterns and common sources of PCBs and OCPs were analyzed using bivariate and multivariate statistics. A total of 947 blood samples from study participants were analyzed for OCP and...
Source: Environment International - April 26, 2024 Category: Environmental Health Authors: Danae Costopoulou Kleopatra Kedikoglou Marina Vafeiadi Theano Roumeliotaki Katerina Margetaki Euripides G Stephanou Antonis Myridakis Leondios Leondiadis Source Type: research