Advancements in the management of obesity: a review of current evidence and emerging therapies
This study aimed to provide a narrative overview of the past, currently available, and future treatment options that offer therapeutic and preventive advantages for obesity management.AREAS COVERED: Historically, rimonabant, and lorcaserin, were approved and used for managing non-syndromic obesity. Currently, orlistat, naltrexone/bupropion, glucagon-like peptide-1 receptor agonist (GLP-1 RA), and a few promising therapeutic agents are under investigation, including retatrutide, cagrilintide and orforglipron, which show promising weight reduction effects. We have developed a search string of the Medical Subject Headings (Me...
Source: Expert Review of Endocrinology and Metabolism - April 30, 2024 Category: Endocrinology Authors: Mohammed Altigani Abdalla Ahmed Emmanuel Ssemmondo Charlotte Mark-Wagstaff Thozhukat Sathyapalan Source Type: research

Transition from pediatrics to adult health care in girls with turner syndrome
Expert Rev Endocrinol Metab. 2024 Apr 25:1-12. doi: 10.1080/17446651.2024.2347265. Online ahead of print.ABSTRACTINTRODUCTION: Turner Syndrome is a rare condition secondary to a complete or partial loss of one X chromosome, leading to a wide spectrum of clinical manifestations. Short stature, gonadal dysgenesis, cardiovascular malformations, and dysmorphic features characterize its common clinical picture.AREAS COVERED: The main endocrine challenges in adolescent girls with Turner Syndrome are puberty induction (closely intertwined with growth) and fertility preservation. We discuss the most important clinical aspects that...
Source: Expert Review of Endocrinology and Metabolism - April 26, 2024 Category: Endocrinology Authors: Chiara Sabbadin Loris Marin Jacopo Manso Chiara Mozzato Valentina Camozzi Alessandra Andrisani Cinzia Sacchetti Caterina Mian Carla Scaroni Laura Guazzarotti Filippo Ceccato Source Type: research

Methods to predict heart failure in diabetes patients
Expert Rev Endocrinol Metab. 2024 Apr 15:1-16. doi: 10.1080/17446651.2024.2342812. Online ahead of print.ABSTRACTINTRODUCTION: Type 2 diabetes mellitus (T2DM) is one of the leading causes of cardiovascular disease and powerful predictor for new-onset heart failure (HF).AREAS COVERED: We focus on the relevant literature covering evidence of risk stratification based on imaging predictors and circulating biomarkers to optimize approaches to preventing HF in DM patients.EXPERT OPINION: Multiple diagnostic algorithms based on echocardiographic parameters of cardiac remodeling including global longitudinal strain/strain rate ar...
Source: Expert Review of Endocrinology and Metabolism - April 16, 2024 Category: Endocrinology Authors: Alexander E Berezin Tetiana A Berezina Uta C Hoppe Michael Lichtenauer Alexander A Berezin Source Type: research

Enhancing type 2 diabetes treatment through digital plans of care - a randomized controlled trial: evaluation of change in patient reported outcome measures
CONCLUSION: In this prospective RCT, the findings point to how the provision of personalized care plans can result in an improvement in individuals' self-rated QoL. This may lead to longer term health benefits.PMID:38567714 | DOI:10.1080/17446651.2024.2334220 (Source: Expert Review of Endocrinology and Metabolism)
Source: Expert Review of Endocrinology and Metabolism - April 3, 2024 Category: Endocrinology Authors: Adrian Heald Sarah Roberts Lucia Albelda Gimeno Alison White Erin Gilingham Reena Patel Kelly Bowden Davies Anuj Saboo Martin Gibson Jonathan Abraham Source Type: research