Expert Review of Molecular Diagnostics This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Artificial Intelligence in Digital Histopathology for predicting patient prognosis and treatment efficacy in breast cancer
Expert Rev Mol Diagn. 2024 Apr 24. doi: 10.1080/14737159.2024.2346545. Online ahead of print.ABSTRACTINTRODUCTION: Histological images contain phenotypic information predictive of patient outcomes. Due to the heavy workload of pathologists, the time-consuming nature of quantitatively assessing histological features, and human eye limitations to recognize spatial patterns, manually extracting prognostic information in routine pathological workflows remains challenging. Digital pathology has facilitated the mining and quantification of these features utilizing whole-slide image (WSI) scanners and artificial intelligence (AI)...
Source: Expert Review of Molecular Diagnostics - April 24, 2024 Category: Laboratory Medicine Authors: William M Gallagher Christine McCaffrey Chowdhury Jahangir Clodagh Murphy Caoimbhe Burke Arman Rahman Source Type: research

Clinical utilization of airway inflammatory biomarkers in the prediction and monitoring of clinical outcomes in patients with chronic obstructive pulmonary disease
Expert Rev Mol Diagn. 2024 Apr 18. doi: 10.1080/14737159.2024.2344777. Online ahead of print.ABSTRACTINTRODUCTION: Chronic obstructive pulmonary disease (COPD) accounts for 545 million people living with chronic respiratory disorders and is the third leading cause of morbidity and mortality around the world. COPD is a progressive disease, characterized by episodes of acute worsening of symptoms such as cough, dyspnea, and sputum production.AREAS COVERED: Airway inflammation is a prominent feature of COPD. Chronic airway inflammation results in airway structural remodeling and emphysema. Persistent airway inflammation is a ...
Source: Expert Review of Molecular Diagnostics - April 18, 2024 Category: Laboratory Medicine Authors: Dina Yehia Clarus Leung Don D Sin Source Type: research

The emerging role of liquid biopsy in oral squamous cell carcinoma detection: advantages and challenges
Expert Rev Mol Diagn. 2024 Apr;24(4):311-331. doi: 10.1080/14737159.2024.2340997. Epub 2024 Apr 12.ABSTRACTINTRODUCTION: Oral Squamous Cell Carcinoma (OSCC), the sixth most widespread malignancy in the world, accounts for 90% of all cases of oral cancer. The primary risk factors are tobacco chewing, alcohol consumption, viral infection, and genetic modifications. OSCC has a high morbidity rate due to the lack of early diagnostic methods. Nowadays, liquid biopsy plays a vital role in the initial diagnosis of oral cancer. ctNAs extracted from saliva and serum/plasma offer meaningful insights into tumor genetics and dynamics....
Source: Expert Review of Molecular Diagnostics - April 12, 2024 Category: Laboratory Medicine Authors: Sudha Gupta Brijesh Singh Rajul Abhishek Sameer Gupta Manisha Sachan Source Type: research

The emerging role of liquid biopsy in oral squamous cell carcinoma detection: advantages and challenges
Expert Rev Mol Diagn. 2024 Apr 12:1-21. doi: 10.1080/14737159.2024.2340997. Online ahead of print.ABSTRACTINTRODUCTION: Oral Squamous Cell Carcinoma (OSCC), the sixth most widespread malignancy in the world, accounts for 90% of all cases of oral cancer. The primary risk factors are tobacco chewing, alcohol consumption, viral infection, and genetic modifications. OSCC has a high morbidity rate due to the lack of early diagnostic methods. Nowadays, liquid biopsy plays a vital role in the initial diagnosis of oral cancer. ctNAs extracted from saliva and serum/plasma offer meaningful insights into tumor genetics and dynamics. ...
Source: Expert Review of Molecular Diagnostics - April 12, 2024 Category: Laboratory Medicine Authors: Sudha Gupta Brijesh Singh Rajul Abhishek Sameer Gupta Manisha Sachan Source Type: research

Body fluid markers for multiple sclerosis and differential diagnosis from atypical demyelinating disorders
Expert Rev Mol Diagn. 2024 Mar 27:1-15. doi: 10.1080/14737159.2024.2334849. Online ahead of print.ABSTRACTINTRODUCTION: Body fluid markers could be helpful to predict the conversion into clinically definite multiple sclerosis (MS) in people with a first demyelinating event of the central nervous system (CNS). Consequently, biomarkers such as oligoclonal bands, which are integrated in the current MS diagnostic criteria, could assist early MS diagnosis.AREAS COVERED: This review examines existing knowledge on a broad spectrum of body fluid markers in people with a first CNS demyelinating event, explores their potential to pr...
Source: Expert Review of Molecular Diagnostics - March 27, 2024 Category: Laboratory Medicine Authors: Angelika Bauer Harald Hegen Markus Reindl Source Type: research