Isolation of four new monoterpenes from Ailanthus altissima (mill.) Swingle and their enzyme inhibitory effects
Fitoterapia. 2024 May 1:105984. doi: 10.1016/j.fitote.2024.105984. Online ahead of print.ABSTRACTA phytochemical study of the ethanol extract from Ailanthus altissima (Mill.) Swingle leaves resulted in the isolation of four new monoterpenoids (1-3, 5). The structures were elucidated using HRESIMS data, NMR spectroscopic data, quantum chemical calculations for NMR and ECD, and custom DP4+ probability analysis. Additionally, the absolute configuration of sugar was determined by acid hydrolysis. Compounds 1-4 are cyclogeraniane monocyclic monoterpenes, while compound 5 contains an acyclic mycrane monoterpenes skeleton. Anti-t...
Source: Fitoterapia - May 3, 2024 Category: Biochemistry Authors: Qi Song Zhi-Kang Duan Ya-Nuo Tan Zhi-Heng Gao Dai Liu Jin-Le Hao Bin Lin Xiao-Xiao Huang Shao-Jiang Song Source Type: research
A comprehensive review on ethnomedicinal, phytochemical and pharmacological properties of genus Bistorta (L.) scop
The objective of this review is to present up-to-date information from the scientific literature about the phytochemistry, pharmacology, and toxicology of Bistorta. At present, there is a lack of a comprehensive review that consolidates the various scientific studies conducted on the genus Bistorta. To address this knowledge gap, a global review has been compiled on the genus Bistorta, which emphasizes ethnomedicinal, phytochemistry, and pharmacology. To gather information about Bistorta, relevant keywords were used to search internet databases including Google scholar, PubMed, ResearchGate, Web of Science, Europe PMC, CNK...
Source: Fitoterapia - May 2, 2024 Category: Biochemistry Authors: Hanan Javid Ishrat Shaheen Roof Ul Qadir Junaid Ahmad Magray Bilal Ahmad Wani Irshad A Nawchoo Shabana Gulzar Source Type: research
A comprehensive review on ethnomedicinal, phytochemical and pharmacological properties of genus Bistorta (L.) scop
The objective of this review is to present up-to-date information from the scientific literature about the phytochemistry, pharmacology, and toxicology of Bistorta. At present, there is a lack of a comprehensive review that consolidates the various scientific studies conducted on the genus Bistorta. To address this knowledge gap, a global review has been compiled on the genus Bistorta, which emphasizes ethnomedicinal, phytochemistry, and pharmacology. To gather information about Bistorta, relevant keywords were used to search internet databases including Google scholar, PubMed, ResearchGate, Web of Science, Europe PMC, CNK...
Source: Fitoterapia - May 2, 2024 Category: Biochemistry Authors: Hanan Javid Ishrat Shaheen Roof Ul Qadir Junaid Ahmad Magray Bilal Ahmad Wani Irshad A Nawchoo Shabana Gulzar Source Type: research
Anogeissus leiocarpus (DC.) Guill. & amp; Perr. (Combretaceae): A review of the traditional uses, phytochemistry and pharmacology of African birch
Fitoterapia. 2024 Apr 29:105979. doi: 10.1016/j.fitote.2024.105979. Online ahead of print.ABSTRACTAnogeissus leiocarpus (DC.) Guill. & Perr. belongs to the family Combretaceae and is used both by African traditional medical practitioners and livestock rearers to treat diseases such as African trypanosomiasis, animal diarrhoea, asthma, cancer, cough, diabetes, dysentery, erectile dysfunction, fever, giardiasis, helminthiases, meningitis, menstrual disorders, monkeypox, oral infections, poliomyelitis, sickle cell anaemia, snake bites, toothache, urinary schistosomiasis, and yellow fever. Some of these activities have bee...
Source: Fitoterapia - May 1, 2024 Category: Biochemistry Authors: Yemi A Adekunle Babatunde B Samuel Lutfun Nahar Amos A Fatokun Satyajit D Sarker Source Type: research
Effectiveness of Semecarpus anacardium fruits in cancer and inflammatory diseases: A mini review
CONCLUSION: The findings will provide more support for investigating SCA fruits in cancer treatment and will furnish thorough reference data and recommendations for future studies on this botanical medication.PMID:38685508 | DOI:10.1016/j.fitote.2024.105978 (Source: Fitoterapia)
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Ashwini Kumar Mishra S L Neha Ankit Jain Chandrashekhar Y Jagtap Ganesh Dane Shweta Paroha Pravat Kumar Sahoo Source Type: research
In vivo anti-inflammatory activity of BACCHARIN from BRAZILIAN green PROPOLIS
Fitoterapia. 2024 Apr 27;175:105975. doi: 10.1016/j.fitote.2024.105975. Online ahead of print.ABSTRACTBaccharin is one of the major compounds found in Brazilian green propolis and its botanical source, Baccharis dracunculifolia. Considering the biological effects of propolis and B. dracunculifolia, this study aims to evaluate the analgesic and anti-inflammatory potential of baccharin. The neurodepressor potential was performed by the open field test, analgesia by mechanical stimulation with Dynamic Plantar Aesthesiometer, and by thermal stimulation with Hargreaves apparatus. In addition, the anti-inflammatory potential was...
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Silvio Almeida-Junior K átia Roberta Prieto de Oliveira La ís Prado Marques Jo ão Guilherme Martins Heloisa Ubeda Mario Ferreira Concei ção Santos Marcela Aldrovani Rodrigues Marcio Lu ís Andrade E Silva S érgio Ricardo Ambrósio Jairo Kenupp Basto Source Type: research
Diarylheptanoids with neuroprotective effects from Alpinia officinarum rhizomes
This study lay the foundation for the application of Alpinia officinarum rhizomes.PMID:38685510 | DOI:10.1016/j.fitote.2024.105980 (Source: Fitoterapia)
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Liping Mu Ji Wang Tang Zhou Wenhao Qiao Weiyan Hu Rongping Zhang Xinglong Chen Source Type: research
Chemical constituents from Notopterygium incisum and their anti-neuroinflammatory activity
Fitoterapia. 2024 Apr 27:105976. doi: 10.1016/j.fitote.2024.105976. Online ahead of print.ABSTRACTPhytochemical research on an extract of Notopterygium incisum yielded fifteen compounds (1-15), including four previously undescribed compounds (10-13). The structures of the unreported compounds were elucidated by spectroscopic and spectrometric data analysis such as 1D and 2D NMR, IR and HR-ESI-MS. Compounds 1-5 and 10-14 were isolated from N. incisum for the first time. 7S⁎,8R⁎-Phenethyl-(7-methoxy-8-isoeugenol)-ferulate (10), 7S⁎,8R⁎-p-hydroxyphenethyl-(7-methoxy-8-isoeugenol)-ferulate (11), 7S⁎,8R⁎-benzyl-(7-m...
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Li-Mei Ma Jiao-Tai Shi Tian Chai Mohammad Reza Naghavi Huan-Yan Liu Ai-Mei Yang Jun Wang Jun-Li Yang Source Type: research
Anti-inflammatory naphthoquinone-monoterpene adducts and neolignans from Eugenia caryophyllata
Fitoterapia. 2024 Apr 27;175:105982. doi: 10.1016/j.fitote.2024.105982. Online ahead of print.ABSTRACTA phytochemical investigation on the buds of edible medicinal plant, Eugenia carvophyllata, led to the discovery of seven new compounds, caryophones A-G (1-7), along with two biogenetically-related known ones, 2-methoxy-7-methyl-1,4-naphthalenedione (8) and eugenol (9). Compounds 1-3 represent the first examples of C-5-C-1' connected naphthoquinone-monoterpene adducts with a new carbon skeleton. Compounds 4-7 are a class of novel neolignans with unusual linkage patterns, in which the C-9 position of one phenylpropene unit ...
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Xue-Yi Li Jun Jiang Beiyi Shu Rui-Li Huang Hai-Xia Yang Ya-Li Chen Wei Tang Wen-Cai Ye Ying Wang Xiao-Jun Huang Jian-Guo Song Source Type: research
Oleanane and 30-noroleanane triterpenoids from the roots of Paeonia lactiflora
Fitoterapia. 2024 Apr 27:105981. doi: 10.1016/j.fitote.2024.105981. Online ahead of print.ABSTRACTAn investigation of EtOAc extract from the roots of Paeonia lactiflora yielded three new 30-noroleanane triterpenoids paeonenoides L-N (1-3) and one new oleanane triterpenoid paeonenoide O (4) together with 7 known compounds (5-11). Extensive spectrographic experiments were applied to identify the structures of 1-4, and their absolute configurations were unambiguously determined by theoretical calculations of ECD spectra, as well as the single-crystal X-ray diffraction analysis. Compounds 8, 9 and 10 were isolated from the Pae...
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Xiao-Feng Xia Ling-Yan Wang Gui-Yang Xia Huan Xia Lin-Nan Zhou Wan-Ting Li Peng-Cheng Lin Sheng Lin Source Type: research
Effectiveness of Semecarpus anacardium fruits in cancer and inflammatory diseases: A mini review
CONCLUSION: The findings will provide more support for investigating SCA fruits in cancer treatment and will furnish thorough reference data and recommendations for future studies on this botanical medication.PMID:38685508 | DOI:10.1016/j.fitote.2024.105978 (Source: Fitoterapia)
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Ashwini Kumar Mishra S L Neha Ankit Jain Chandrashekhar Y Jagtap Ganesh Dane Shweta Paroha Pravat Kumar Sahoo Source Type: research
In vivo anti-inflammatory activity of BACCHARIN from BRAZILIAN green PROPOLIS
Fitoterapia. 2024 Apr 27:105975. doi: 10.1016/j.fitote.2024.105975. Online ahead of print.ABSTRACTBaccharin is one of the major compounds found in Brazilian green propolis and its botanical source, Baccharis dracunculifolia. Considering the biological effects of propolis and B. dracunculifolia, this study aims to evaluate the analgesic and anti-inflammatory potential of baccharin. The neurodepressor potential was performed by the open field test, analgesia by mechanical stimulation with Dynamic Plantar Aesthesiometer, and by thermal stimulation with Hargreaves apparatus. In addition, the anti-inflammatory potential was ach...
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Silvio Almeida-Junior K átia Roberta Prieto de Oliveira La ís Prado Marques Jo ão Guilherme Martins Heloisa Ubeda Mario Ferreira Concei ção Santos Marcela Aldrovani Rodrigues Marcio Lu ís Andrade E Silva S érgio Ricardo Ambrósio Jairo Kenupp Basto Source Type: research
Diarylheptanoids with neuroprotective effects from Alpinia officinarum rhizomes
This study lay the foundation for the application of Alpinia officinarum rhizomes.PMID:38685510 | DOI:10.1016/j.fitote.2024.105980 (Source: Fitoterapia)
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Liping Mu Ji Wang Tang Zhou Wenhao Qiao Weiyan Hu Rongping Zhang Xinglong Chen Source Type: research
Chemical constituents from Notopterygium incisum and their anti-neuroinflammatory activity
Fitoterapia. 2024 Apr 27:105976. doi: 10.1016/j.fitote.2024.105976. Online ahead of print.ABSTRACTPhytochemical research on an extract of Notopterygium incisum yielded fifteen compounds (1-15), including four previously undescribed compounds (10-13). The structures of the unreported compounds were elucidated by spectroscopic and spectrometric data analysis such as 1D and 2D NMR, IR and HR-ESI-MS. Compounds 1-5 and 10-14 were isolated from N. incisum for the first time. 7S⁎,8R⁎-Phenethyl-(7-methoxy-8-isoeugenol)-ferulate (10), 7S⁎,8R⁎-p-hydroxyphenethyl-(7-methoxy-8-isoeugenol)-ferulate (11), 7S⁎,8R⁎-benzyl-(7-m...
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Li-Mei Ma Jiao-Tai Shi Tian Chai Mohammad Reza Naghavi Huan-Yan Liu Ai-Mei Yang Jun Wang Jun-Li Yang Source Type: research
Anti-inflammatory naphthoquinone-monoterpene adducts and neolignans from Eugenia caryophyllata
Fitoterapia. 2024 Apr 27:105982. doi: 10.1016/j.fitote.2024.105982. Online ahead of print.ABSTRACTA phytochemical investigation on the buds of edible medicinal plant, Eugenia carvophyllata, led to the discovery of seven new compounds, caryophones A-G (1-7), along with two biogenetically-related known ones, 2-methoxy-7-methyl-1,4-naphthalenedione (8) and eugenol (9). Compounds 1-3 represent the first examples of C-5-C-1' connected naphthoquinone-monoterpene adducts with a new carbon skeleton. Compounds 4-7 are a class of novel neolignans with unusual linkage patterns, in which the C-9 position of one phenylpropene unit coup...
Source: Fitoterapia - April 30, 2024 Category: Biochemistry Authors: Xue-Yi Li Jun Jiang Beiyi Shu Rui-Li Huang Hai-Xia Yang Ya-Li Chen Wei Tang Wen-Cai Ye Ying Wang Xiao-Jun Huang Jian-Guo Song Source Type: research
