Is there potential for estradiol receptor signaling in lophotrochozoans?
Gen Comp Endocrinol. 2024 Apr 25:114519. doi: 10.1016/j.ygcen.2024.114519. Online ahead of print.ABSTRACTEstrogen receptors (ERs) are thought to be the ancestor of all steroid receptors and are present in most lophotrochozoans studied to date, including molluscs, annelids, and rotifers. A number of studies have investigated the functional role of estrogen receptors in invertebrate species, although most are in molluscs, where the receptor is constitutively active. In vitro experiments provided evidence for ligand-activated estrogen receptors in annelids, raising important questions about the role of estrogen signalling in ...
Source: General and Comparative Endocrinology - April 27, 2024 Category: Endocrinology Authors: A M Murillo J Y Wilson Source Type: research

Recent insights into egg quality and larval vitality of the European EEL anguilla anguilla
Gen Comp Endocrinol. 2024 Apr 24:114531. doi: 10.1016/j.ygcen.2024.114531. Online ahead of print.ABSTRACTTo date, the eel industry still depends on wild-caught juveniles that are grown to marketable size. There is an urgent need to close the eel life cycle in captivity to make aquaculture independent of the natural population. With this artificial reproduction protocol, yolk-sac larvae can be produced but egg quality may be impaired. Low survival rates and high deformity rates are frequently observed during the first week after hatching. Over the past four years, we have conducted studies with the aim to optimize the artif...
Source: General and Comparative Endocrinology - April 26, 2024 Category: Endocrinology Authors: Pauline J éhannet Leon T N Heinsbroek William Swinkels Arjan P Palstra Source Type: research

Corrigendum to "Does variation in glucocorticoid concentrations predict fitness? A phylogenetic meta-analysis" [Gen. Comp. Endocrinol. 300 (2021) 113611]
Gen Comp Endocrinol. 2024 Apr 26:114518. doi: 10.1016/j.ygcen.2024.114518. Online ahead of print.NO ABSTRACTPMID:38670848 | DOI:10.1016/j.ygcen.2024.114518 (Source: General and Comparative Endocrinology)
Source: General and Comparative Endocrinology - April 26, 2024 Category: Endocrinology Authors: Laura A Schoenle Cedric Zimmer Eliot T Miller Maren N Vitousek Source Type: research

The regulation of prolactin secretion and its targeting function of teleost
Gen Comp Endocrinol. 2024 Apr 22:114530. doi: 10.1016/j.ygcen.2024.114530. Online ahead of print.ABSTRACTProlactin is involved in regulating various physiological activities of vertebrates and is one of the most momentous pituitary hormones. However, not enough attention is currently paid to prolactin, especially in teleost. This paper aims to gather, organize, and analyze recent studies on the regulation and functions of prolactin. By comparing with other animal groups, it highlights the significant role of prolactin in fish reproduction, immunity, growth, and osmotic pressure regulation, as well as the upstream and downs...
Source: General and Comparative Endocrinology - April 24, 2024 Category: Endocrinology Authors: Zhu Tiansheng Li Wensheng Source Type: research

The regulation of prolactin secretion and its targeting function of teleost
Gen Comp Endocrinol. 2024 Apr 22:114530. doi: 10.1016/j.ygcen.2024.114530. Online ahead of print.ABSTRACTProlactin is involved in regulating various physiological activities of vertebrates and is one of the most momentous pituitary hormones. However, not enough attention is currently paid to prolactin, especially in teleost. This paper aims to gather, organize, and analyze recent studies on the regulation and functions of prolactin. By comparing with other animal groups, it highlights the significant role of prolactin in fish reproduction, immunity, growth, and osmotic pressure regulation, as well as the upstream and downs...
Source: General and Comparative Endocrinology - April 24, 2024 Category: Endocrinology Authors: Zhu Tiansheng Li Wensheng Source Type: research

The regulation of prolactin secretion and its targeting function of teleost
Gen Comp Endocrinol. 2024 Apr 22:114530. doi: 10.1016/j.ygcen.2024.114530. Online ahead of print.ABSTRACTProlactin is involved in regulating various physiological activities of vertebrates and is one of the most momentous pituitary hormones. However, not enough attention is currently paid to prolactin, especially in teleost. This paper aims to gather, organize, and analyze recent studies on the regulation and functions of prolactin. By comparing with other animal groups, it highlights the significant role of prolactin in fish reproduction, immunity, growth, and osmotic pressure regulation, as well as the upstream and downs...
Source: General and Comparative Endocrinology - April 24, 2024 Category: Endocrinology Authors: Zhu Tiansheng Li Wensheng Source Type: research

Irisin as an emerging target in the regulation of reproductive functions in health and disease
Gen Comp Endocrinol. 2024 Apr 19:114529. doi: 10.1016/j.ygcen.2024.114529. Online ahead of print.ABSTRACTGerm cells are highly conserved in the gonads, nurtured to either develop into a gamete or self-renew into a stem cell reserve. Preserving the germ cell pool and protecting the reproductive organs is essential for maintaining an individual's fertility. Several factors, including a sedentary lifestyle, pollutants, hormonal disruption, drugs, and a disease condition, have been shown to impair normal reproductive function. Irisin has recently been identified as an adipomyokine involved in modulating physiological functions...
Source: General and Comparative Endocrinology - April 21, 2024 Category: Endocrinology Authors: Sree Vaishnavi Nalla P Jayapradha None Lalruatmawii K Nandheeswari Pratik Naxine G Vigneshwaran Gaurav Rohilla Itishree Dubey Sapana Kushwaha Source Type: research

Kisspeptin administration may promote precopulatory behavior in male rats independently or supplementally to testosterone and contribute to proceptive behavior in female partners, reducing mating failure
In conclusion, kisspeptin may involve an as-yet-unidentified neural pathway in sexual desire independently of the HPG axis.PMID:38643848 | DOI:10.1016/j.ygcen.2024.114528 (Source: General and Comparative Endocrinology)
Source: General and Comparative Endocrinology - April 21, 2024 Category: Endocrinology Authors: Shota Yamamoto Ryosuke Arakaki Hiroki Noguchi Asuka Takeda Maimi Uchishiba Shuhei Kamada Ayuka Mineda Masafumi Kon Riyo Kinouchi Yuri Yamamoto Kanako Yoshida Takashi Kaji Nobuo Shinohara Takeshi Iwasa Source Type: research

Irisin as an emerging target in the regulation of reproductive functions in health and disease
Gen Comp Endocrinol. 2024 Apr 19:114529. doi: 10.1016/j.ygcen.2024.114529. Online ahead of print.ABSTRACTGerm cells are highly conserved in the gonads, nurtured to either develop into a gamete or self-renew into a stem cell reserve. Preserving the germ cell pool and protecting the reproductive organs is essential for maintaining an individual's fertility. Several factors, including a sedentary lifestyle, pollutants, hormonal disruption, drugs, and a disease condition, have been shown to impair normal reproductive function. Irisin has recently been identified as an adipomyokine involved in modulating physiological functions...
Source: General and Comparative Endocrinology - April 21, 2024 Category: Endocrinology Authors: Sree Vaishnavi Nalla P Jayapradha None Lalruatmawii K Nandheeswari Pratik Naxine G Vigneshwaran Gaurav Rohilla Itishree Dubey Sapana Kushwaha Source Type: research

Kisspeptin administration may promote precopulatory behavior in male rats independently or supplementally to testosterone and contribute to proceptive behavior in female partners, reducing mating failure
In conclusion, kisspeptin may involve an as-yet-unidentified neural pathway in sexual desire independently of the HPG axis.PMID:38643848 | DOI:10.1016/j.ygcen.2024.114528 (Source: General and Comparative Endocrinology)
Source: General and Comparative Endocrinology - April 21, 2024 Category: Endocrinology Authors: Shota Yamamoto Ryosuke Arakaki Hiroki Noguchi Asuka Takeda Maimi Uchishiba Shuhei Kamada Ayuka Mineda Masafumi Kon Riyo Kinouchi Yuri Yamamoto Kanako Yoshida Takashi Kaji Nobuo Shinohara Takeshi Iwasa Source Type: research

Molecular characterization of GPR84 in domestic cats
This study aimed to present the molecular characterization of GPR84 in domestic cats. The deduced amino acid sequence of the feline GPR84 shows high sequence homology (83-89 %) with the orthologues from other mammalians by cDNA cloning of feline GPR84. Remarkably high mRNA expression was observed in the bone marrow by Q-PCR analysis. The inhibition of intracellular cAMP concentration was observed in cells transfected with feline GPR84 and treated with medium-chain fatty acids. Immunostaining of GPR84 and free fatty acid receptor 2 (FFAR2)/GPR43 in the bone marrow, where high mRNA expression was observed, showed reactions i...
Source: General and Comparative Endocrinology - April 19, 2024 Category: Endocrinology Authors: Ichiro Yamamoto Masaki Michishita Koki Fujita Tamami Sakai Noriyasu Sasaki Koh Kawasumi Source Type: research

Characterization of myoinhibitory peptide signaling system and its implication in larval metamorphosis and spawning behavior in Pacific abalone
In this study, we identified the MIP signaling system in the Pacific abalone Haliotis discus hannai (Hdh). Similar to the invertebrate MIPs, a total of eight paracopies of MIPs (named Hdh-MIP1 to Hdh-MIP8), harboring a WX5-7Wamide motif, except for Hdh-MIP2, were found in the Hdh-MIP precursor. Furthermore, we characterized a functional Hdh-MIPR, which responded to the Hdh-MIPs, except for Hdh-MIP2, possibly linked with the PKC/Ca2+ and PKA/cAMP signaling pathways. Hdh-MIPs delayed larval metamorphosis but increased the spawning behavior. These results suggest that the Hdh-MIP signaling system provides insights into the un...
Source: General and Comparative Endocrinology - April 15, 2024 Category: Endocrinology Authors: Sungwoo Park Mi Ae Kim Young Chang Sohn Source Type: research

Characterization of myoinhibitory peptide signaling system and its implication in larval metamorphosis and spawning behavior in Pacific abalone
In this study, we identified the MIP signaling system in the Pacific abalone Haliotis discus hannai (Hdh). Similar to the invertebrate MIPs, a total of eight paracopies of MIPs (named Hdh-MIP1 to Hdh-MIP8), harboring a WX5-7Wamide motif, except for Hdh-MIP2, were found in the Hdh-MIP precursor. Furthermore, we characterized a functional Hdh-MIPR, which responded to the Hdh-MIPs, except for Hdh-MIP2, possibly linked with the PKC/Ca2+ and PKA/cAMP signaling pathways. Hdh-MIPs delayed larval metamorphosis but increased the spawning behavior. These results suggest that the Hdh-MIP signaling system provides insights into the un...
Source: General and Comparative Endocrinology - April 15, 2024 Category: Endocrinology Authors: Sungwoo Park Mi Ae Kim Young Chang Sohn Source Type: research

Characterization of myoinhibitory peptide signaling system and its implication in larval metamorphosis and spawning behavior in Pacific abalone
In this study, we identified the MIP signaling system in the Pacific abalone Haliotis discus hannai (Hdh). Similar to the invertebrate MIPs, a total of eight paracopies of MIPs (named Hdh-MIP1 to Hdh-MIP8), harboring a WX5-7Wamide motif, except for Hdh-MIP2, were found in the Hdh-MIP precursor. Furthermore, we characterized a functional Hdh-MIPR, which responded to the Hdh-MIPs, except for Hdh-MIP2, possibly linked with the PKC/Ca2+ and PKA/cAMP signaling pathways. Hdh-MIPs delayed larval metamorphosis but increased the spawning behavior. These results suggest that the Hdh-MIP signaling system provides insights into the un...
Source: General and Comparative Endocrinology - April 15, 2024 Category: Endocrinology Authors: Sungwoo Park Mi Ae Kim Young Chang Sohn Source Type: research

Baseline and stress-induced steroid plasma levels and immune function vary annually and are associated with vocal activity in male toads (Rhinella icterica)
This study investigated annual variation in plasma corticosterone and testosterone levels, plasma bacterial killing ability (BKA), and neutrophil to lymphocyte ratio (NLR) in free-living male toads (Rhinella icterica). Toads were sampled in the field (baseline) and 1 h-post restraint over five months, and we considered the occurrence of vocal activity. Baseline corticosterone, testosterone, and BKA showed higher values during the reproductive period, specifically in calling male toads. The NLR was similar throughout the year, but higher values were observed in calling toads. Moreover, baseline NLR and BKA were positively c...
Source: General and Comparative Endocrinology - April 14, 2024 Category: Endocrinology Authors: Braz Titon Junior Adriana Maria Giorgi Barsotti Stefanny Christie Monteiro Titon Renata Ibelli Vaz Aymam Cobo de Figueiredo Ronyelle Vasconcelos-Teixeira Carlos A Navas Fernando Ribeiro Gomes Source Type: research