Epidemiology of Disorders of the Gut-Brain Interaction: An Appraisal of the Rome IV Criteria and Beyond
Gut Liver. 2024 Apr 29. doi: 10.5009/gnl230396. Online ahead of print.ABSTRACTDisorders of the gut-brain interaction (DGBIs) are presently classified into mutually exclusive anatomical area-related symptom-based categories according to the Rome IV criteria. The pathophysiology of visceral nociception, which contributes to the wide range of symptoms of DGBIs, involves complex psychobiological processes arising from the bidirectional interactions of multiple systems at the gut and brain levels, which affect symptom expression and illness behaviors. The attitude toward an illness and expression of pain and bowel habit vary ac...
Source: Gut and Liver - April 29, 2024 Category: Gastroenterology Authors: Gautam Ray Uday Chand Ghoshal Source Type: research

Trends in Mortality Related to Hepatitis B and C from 1990 to 2019 in the Western Pacific Region
CONCLUSIONS: : Although the mortality rate from hepatitis B and C decreased from 1990 to 2019, notable variation was observed among 27 Western Pacific countries. Efforts targeting hepatitis B and C prevention and treatment are still required in this region, especially for the pandemic countries.PMID:38638100 | DOI:10.5009/gnl230023 (Source: Gut and Liver)
Source: Gut and Liver - April 19, 2024 Category: Gastroenterology Authors: Hua Zhou Mengxia Yan Datian Che Bin Wu Source Type: research

The Circular RNA Circ_0043947 Promoted Gastric Cancer Progression by Sponging miR-384 to Regulate CREB1 Expression
CONCLUSIONS: : Circ_0043947 acted as an oncogenic factor in GC to mediate GC cell proliferation, migration, and invasion, the cell cycle and apoptosis by regulating the miR-384/CREB1 axis. Circ_0043947 may be a potential target for GC diagnosis and therapy.PMID:38638101 | DOI:10.5009/gnl230173 (Source: Gut and Liver)
Source: Gut and Liver - April 19, 2024 Category: Gastroenterology Authors: Chongxin Zhang Fan Zhang Yukun Li Pengfei Yang Yang Liu Wenxiao Yang Source Type: research

Trends in Mortality Related to Hepatitis B and C from 1990 to 2019 in the Western Pacific Region
CONCLUSIONS: : Although the mortality rate from hepatitis B and C decreased from 1990 to 2019, notable variation was observed among 27 Western Pacific countries. Efforts targeting hepatitis B and C prevention and treatment are still required in this region, especially for the pandemic countries.PMID:38638100 | DOI:10.5009/gnl230023 (Source: Gut and Liver)
Source: Gut and Liver - April 19, 2024 Category: Gastroenterology Authors: Hua Zhou Mengxia Yan Datian Che Bin Wu Source Type: research

The Circular RNA Circ_0043947 Promoted Gastric Cancer Progression by Sponging miR-384 to Regulate CREB1 Expression
CONCLUSIONS: : Circ_0043947 acted as an oncogenic factor in GC to mediate GC cell proliferation, migration, and invasion, the cell cycle and apoptosis by regulating the miR-384/CREB1 axis. Circ_0043947 may be a potential target for GC diagnosis and therapy.PMID:38638101 | DOI:10.5009/gnl230173 (Source: Gut and Liver)
Source: Gut and Liver - April 19, 2024 Category: Gastroenterology Authors: Chongxin Zhang Fan Zhang Yukun Li Pengfei Yang Yang Liu Wenxiao Yang Source Type: research

Trends in Mortality Related to Hepatitis B and C from 1990 to 2019 in the Western Pacific Region
CONCLUSIONS: : Although the mortality rate from hepatitis B and C decreased from 1990 to 2019, notable variation was observed among 27 Western Pacific countries. Efforts targeting hepatitis B and C prevention and treatment are still required in this region, especially for the pandemic countries.PMID:38638100 | DOI:10.5009/gnl230023 (Source: Gut and Liver)
Source: Gut and Liver - April 19, 2024 Category: Gastroenterology Authors: Hua Zhou Mengxia Yan Datian Che Bin Wu Source Type: research

The Circular RNA Circ_0043947 Promoted Gastric Cancer Progression by Sponging miR-384 to Regulate CREB1 Expression
CONCLUSIONS: : Circ_0043947 acted as an oncogenic factor in GC to mediate GC cell proliferation, migration, and invasion, the cell cycle and apoptosis by regulating the miR-384/CREB1 axis. Circ_0043947 may be a potential target for GC diagnosis and therapy.PMID:38638101 | DOI:10.5009/gnl230173 (Source: Gut and Liver)
Source: Gut and Liver - April 19, 2024 Category: Gastroenterology Authors: Chongxin Zhang Fan Zhang Yukun Li Pengfei Yang Yang Liu Wenxiao Yang Source Type: research

Trends in Mortality Related to Hepatitis B and C from 1990 to 2019 in the Western Pacific Region
CONCLUSIONS: : Although the mortality rate from hepatitis B and C decreased from 1990 to 2019, notable variation was observed among 27 Western Pacific countries. Efforts targeting hepatitis B and C prevention and treatment are still required in this region, especially for the pandemic countries.PMID:38638100 | DOI:10.5009/gnl230023 (Source: Gut and Liver)
Source: Gut and Liver - April 19, 2024 Category: Gastroenterology Authors: Hua Zhou Mengxia Yan Datian Che Bin Wu Source Type: research

The Circular RNA Circ_0043947 Promoted Gastric Cancer Progression by Sponging miR-384 to Regulate CREB1 Expression
CONCLUSIONS: : Circ_0043947 acted as an oncogenic factor in GC to mediate GC cell proliferation, migration, and invasion, the cell cycle and apoptosis by regulating the miR-384/CREB1 axis. Circ_0043947 may be a potential target for GC diagnosis and therapy.PMID:38638101 | DOI:10.5009/gnl230173 (Source: Gut and Liver)
Source: Gut and Liver - April 19, 2024 Category: Gastroenterology Authors: Chongxin Zhang Fan Zhang Yukun Li Pengfei Yang Yang Liu Wenxiao Yang Source Type: research

Trends in Mortality Related to Hepatitis B and C from 1990 to 2019 in the Western Pacific Region
CONCLUSIONS: : Although the mortality rate from hepatitis B and C decreased from 1990 to 2019, notable variation was observed among 27 Western Pacific countries. Efforts targeting hepatitis B and C prevention and treatment are still required in this region, especially for the pandemic countries.PMID:38638100 | DOI:10.5009/gnl230023 (Source: Gut and Liver)
Source: Gut and Liver - April 19, 2024 Category: Gastroenterology Authors: Hua Zhou Mengxia Yan Datian Che Bin Wu Source Type: research

The Circular RNA Circ_0043947 Promoted Gastric Cancer Progression by Sponging miR-384 to Regulate CREB1 Expression
CONCLUSIONS: : Circ_0043947 acted as an oncogenic factor in GC to mediate GC cell proliferation, migration, and invasion, the cell cycle and apoptosis by regulating the miR-384/CREB1 axis. Circ_0043947 may be a potential target for GC diagnosis and therapy.PMID:38638101 | DOI:10.5009/gnl230173 (Source: Gut and Liver)
Source: Gut and Liver - April 19, 2024 Category: Gastroenterology Authors: Chongxin Zhang Fan Zhang Yukun Li Pengfei Yang Yang Liu Wenxiao Yang Source Type: research

Unraveling the Heterogeneity of CD8+ T-Cell Subsets in Liver Cirrhosis: Implications for Disease Progression
CONCLUSIONS: : In summary, this comprehensive study defines specialized CD8+ T-cell subpopulations in cirrhosis, with CXCL13+ Tex cells displaying an exhausted phenotype associated with immune dysregulation and advanced disease. Key genes and pathways regulating these cells present potential therapeutic targets.PMID:38623058 | DOI:10.5009/gnl230345 (Source: Gut and Liver)
Source: Gut and Liver - April 16, 2024 Category: Gastroenterology Authors: Kepu Zheng Leiyang Dai Shengning Zhang Yingpeng Zhao Wang Li Yang Gao Yuanyi Mang Lingfeng Jiao Yu Tang Jianghua Ran Source Type: research

A New Risk Prediction Model for Detecting Endoscopic Activity of Ulcerative Colitis
CONCLUSIONS: : The nomogram, which incorporated activated partial thromboplastin time, fecal occult blood test, β2-globulin level, and fibrinogen degradation products, served as a prospective tool for evaluating UC activity in clinical practices.PMID:38623059 | DOI:10.5009/gnl230370 (Source: Gut and Liver)
Source: Gut and Liver - April 16, 2024 Category: Gastroenterology Authors: Guoyu Guan Sangdan Zhuoga Songbai Zheng Kangqiao Xu Tingwen Weng Wensi Qian Danian Ji Xiaofeng Yu Source Type: research

Long-term Outcome of Asymptomatic Esophageal Eosinophilia
CONCLUSIONS: : Some patients with aEE had improved findings without treatment, whereas others developed symptoms, emphasizing the importance of long-term monitoring and individualized treatment decisions.PMID:38623060 | DOI:10.5009/gnl230398 (Source: Gut and Liver)
Source: Gut and Liver - April 16, 2024 Category: Gastroenterology Authors: Yugo Suzuki Yorinari Ochiai Daisuke Kikuchi Mako Koseki Kenichi Ohashi Shu Hoteya Source Type: research