Histopathological and statistical study of corneal repair in rabbits. A new way to understand corneal recovery
This study was conducted using a formula that combines histologic data categorizing their presence and/or type as beneficial for corneal repair. No statistically significant differences were found between the experimental and control eyes regarding all clinical signs and OCT measurements. However, a linear model using histopathological results showed a period-implant mode interaction with statistical significance (p=0.010). The use of the single-layer amniotic membrane resulted in improved corneal recovery with the stromal side showing better performance in the first week and the epithelial side proving to be more effectiv...
Source: Histology and Histopathology - May 3, 2024 Category: Cytology Authors: Patricia Ram írez-Perdomo Juan Daniel Hern ández-Marrero Santiago Guill én-Molina Pedro Saavedra-Santana M ónica de León-Vera Eduardo Jos é Araujo-Ruano Juan Francisco Loro-Ferrer Juan Jos é Cabrera-Galván Juan Andr és Ramírez-González Source Type: research
The role of CD98 heavy chain in cancer development
Histol Histopathol. 2024 Apr 16:18749. doi: 10.14670/HH-18-749. Online ahead of print.ABSTRACTThe glycoprotein CD98, or CD98 heavy chain (CD98hc), encoded by the SLC3A2 gene, plays a crucial role in cancer development and progression. CD98hc, forming heterodimeric complexes with various light chains, regulates neutral amino acid transport across cell membranes. The intricate interplay between CD98hc, integrins, and amino acid transporters shapes the tumor microenvironment and contributes to tumor growth. Elevated expression of CD98hc in various cancers correlates with poor prognosis, making it a potential prognostic marker...
Source: Histology and Histopathology - May 2, 2024 Category: Cytology Authors: Eunsun Park Hyesung Kim Seokho Yoon Bogun Jang Source Type: research
BPTF promotes glioma development through USP34-mediated de-ubiquitination of FOXC1
In conclusion, the BPTF/FOXC1 axis was identified as a key promotor in glioma development and may be a potential target in the inhibition of glioma development.PMID:38686761 | DOI:10.14670/HH-18-748 (Source: Histology and Histopathology)
Source: Histology and Histopathology - April 30, 2024 Category: Cytology Authors: Yanling Pan Feng Yuan Zhiren Lin Yijie Li Source Type: research
Optimal human ovarian follicle isolation: A review focused on enzymatic digestion
Histol Histopathol. 2024 Apr 12:18747. doi: 10.14670/HH-18-747. Online ahead of print.ABSTRACTThe damage or depletion of ovarian reserves due to aging or cancer treatment can increase the need for fertility preservation techniques. One of the most common ways of supporting fertility in prepubertal girls and women who require immediate cancer treatment is through ovarian tissue cryopreservation and re-transplantation following cancer treatment. However, a more appropriate method should be employed in diseases such as leukemia, where malignant cells may be present in cryopreserved tissue, instead of ovarian tissue transplant...
Source: Histology and Histopathology - April 29, 2024 Category: Cytology Authors: Farnaz Tajbakhsh Somayeh Tavana Mohammad Kazemi Ashtiani Christiani Andrade Amorim Rouhollah Fathi Source Type: research
Protection of Qingfei Xieding prescription from idiopathic pulmonary fibrosis by regulating renin-angiotensin and ferroptosis in MLE-12 cells
Histol Histopathol. 2024 Apr 11:18746. doi: 10.14670/HH-18-746. Online ahead of print.ABSTRACTIdiopathic pulmonary fibrosis (IPF) is a lifelong lung disease, but there is no specific drug for treatment. Qingfei Xieding prescription (QF) is active in the treatment of lung diseases. More comprehensive mechanisms over how QF exhibits anti-pulmonary fibrosis need to be elucidated. TGF-β was used to construct a pulmonary fibrosis cell model in vitro. Bleomycin was applied to induce a lung tissue fibrosis model in mice in vivo. Flow cytometry was used to detect cellular ROS and lipid oxidation levels. Cell substructure was obse...
Source: Histology and Histopathology - April 26, 2024 Category: Cytology Authors: Lifang Sun Xinxin He Jiao Kong Jianying Zhou Source Type: research
Comparison of epoprostenol and viscum album efficiencies in the treatment of avascular necrosis of the femoral head: An experimental animal study
CONCLUSION: Viscum album seems to be effective in decreasing the extention of necrosis and protecting the articular cartilage, and epoprostenol in increasing repair and regeneration.PMID:38661187 | DOI:10.14670/HH-18-745 (Source: Histology and Histopathology)
Source: Histology and Histopathology - April 25, 2024 Category: Cytology Authors: Mert Kumbaraci Banu Sarsik Kumbaraci Basak Doganavsargil Yakut Cenk Can Gulcin Basdemir Semih Aydogdu Source Type: research
The diverse functions of DYRK2 in response to cellular stress
Histol Histopathol. 2024 Apr 8:18744. doi: 10.14670/HH-18-744. Online ahead of print.ABSTRACTTo maintain microenvironmental and cellular homeostasis, cells respond to multiple stresses by activating characteristic cellular mechanisms consisting of receptors, signal transducers, and effectors. Dysfunction of these mechanisms can trigger multiple human diseases as well as cancers. Dual-specificity tyrosine-regulated kinases (DYRKs) are members of the CMGC group and are evolutionarily conserved from yeast to mammals. Previous studies revealed that DYRK2 has important roles in the regulation of the cell cycle and survival in c...
Source: Histology and Histopathology - April 24, 2024 Category: Cytology Authors: Akira Kawamura Saishu Yoshida Kiyotsugu Yoshida Source Type: research
Effect of 3D printing technology-assisted TKA on cartilage tissue in rabbit with knee osteoarthritis
CONCLUSION: 3D printing technology-assisted TKA exhibits a good treatment effect in rabbit KOA. This study provides an important basis for the clinical application of 3D printing technology-assisted TKA in KOA treatment.PMID:38639204 | DOI:10.14670/HH-18-740 (Source: Histology and Histopathology)
Source: Histology and Histopathology - April 19, 2024 Category: Cytology Authors: Guoliang Wang Feng Cheng Jianxun Cui Nan Chen Qing Li Source Type: research
