Indian Journal of Surgical Oncology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Dysgerminoma with Syncytiotrophoblastic Giant Cells Associated with a Concurrent Ectopic Pregnancy
AbstractBackgroundDysgerminomas constitute around 1 –2% of all germ cell tumours. It is very very rare to have dysgerminoma with concurrent pregnancy with an incidence of 0.2–1 per 100,000 pregnancies. It is extremely difficult to conceive with no assisted reproductive interventions and carry it till completion with no complications in a concurre nt dysgerminoma. Dysgerminoma has a characteristic specific histomorphology and is easy to diagnose. However, occasionally, syncytiotrophoblastic differentiation can be seen in dysgerminoma although it is a rare histopathological finding. Also, the raised serum B-HCG levels du...
Source: Indian Journal of Surgical Oncology - May 1, 2024 Category: Cancer & Oncology Source Type: research

The Role of Neoadjuvant and Adjuvant Chemotherapy in Pancreatic Cancer
AbstractPancreatic cancer is an aggressive malignancy. Recurrences are very high despite high-quality surgery necessitating adjuvant therapy. The evolution of adjuvant therapy took several decades and gradually evolved from single-agent chemotherapy to multi-agent chemotherapy. The two important agents that are active in pancreatic cancer are 5-fluorouracil and gemcitabine, and with several combinations showing better results in the subsequent trials, the most recent trial PRODIGE 24 shows a median survival of 54.4  months. The role of neoadjuvant therapy is still evolving in resectable cancers. The role of adjuvant radio...
Source: Indian Journal of Surgical Oncology - April 26, 2024 Category: Cancer & Oncology Source Type: research

Isolated Inguinal Lymph Node Metastasis from Colon Cancer: A Case Report
We reported a rare case of isolated metachronous inguinal lymph node metastasis from colon cancer with a round ligament route of spread as the hypothesized mechanism. Surgical resection with inguinal LN dissection is the preferred treatment option for isolated inguinal lymph node metastasis from colon cancer followed by adjuvant chemotherapy, yet long term follow-up data is needed to support this strategy. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - April 23, 2024 Category: Cancer & Oncology Source Type: research

Short Report of Retained Radiopaque Marker in Gauze and Comparison of Ease of Dislodging and Breaking
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - April 22, 2024 Category: Cancer & Oncology Source Type: research

Ectopic Follicular Variant of Papillary Thyroid Carcinoma in Anterior Neck Region with a Normal Thyroid Gland —A Rare Entity
We report a rare case of ectopic follicular variant of papillary carcinoma in a 73-year-old female with a normal orthotopic thyroid gland. Despite a few reports on ectopic papillary carcinoma thyroid (PTC) in submental, thyroglossal duct cysts, and bronchial cleft cysts with normal pathologic examinations of orthotopic thyroid, only one case of PTC in the anterior neck region without any neoplastic involvement of the orthotopic thyroid gland has been reported. Ectopic thyroid carcinoma should be taken into account in the differential diagnosis of a mass lesion in the front of the neck even in the presence of a normal thyro...
Source: Indian Journal of Surgical Oncology - April 19, 2024 Category: Cancer & Oncology Source Type: research

Utility of Microvascular Reconstruction in Gastrointestinal Cancer Surgery During Complex Resections and Emergency Salvage
AbstractMajor gastrointestinal surgical resections and subsequent reconstruction can occasionally need arterial or venous resection, can encounter variant anatomy, or may lead to injury to vessels. These can lead to arterial and/or venous insufficiency of viscera like the stomach, liver, colon, or spleen. Left unaddressed, these can lead to, partial or total, organ ischemia or necrosis. This can trigger a cascade of systemic clinical complications resulting in significant morbidity or even mortality. The aim of this case series is to highlight the utility of microvascular plastic surgical principles and practices in counte...
Source: Indian Journal of Surgical Oncology - April 15, 2024 Category: Cancer & Oncology Source Type: research

Heterotopic Pancreas: Unusual Cause of Usual Diarrhoea
AbstractHeterotopic pancreas (HP) also known as ectopic pancreas, pancreatic crest or accessory pancreas is the normal pancreatic tissue, found in a remote area other than its natural location, with no anatomic or vascular connection to main pancreatic tissue. It is a rare congenital anomaly and has been reported at many locations such as stomach (antrum) and small intestine. HP is usually an incidental finding and asymptomatic, however there are reports of pancreatitis, obstruction, perforation and malignant transformation as uncommon manifestations. Diagnosis of HP is primarily based on histological examination either by...
Source: Indian Journal of Surgical Oncology - April 14, 2024 Category: Cancer & Oncology Source Type: research

Life Time Saga with Custom Mega Prosthesis in Bone Tumors (The Chennai Experience)
(Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - April 12, 2024 Category: Cancer & Oncology Source Type: research

Treatment Outcomes of Incidental Gallbladder Cancer – Results from a High-Volume Tertiary Care Centre in North India
We present the institutional experience of a high-volume tertiary care center in northern India.  Retrospective analysis of a prospectively maintained database was performed and data of all IGBC patients between January 2014 to December 2021 was analyzed. There were 125 patients of IGBC among the 750 patients of GBC seen during the study period. Of these 125 patients, 72 (57.6%) patients were not eligible for surgery. Successful completion radical cholecystectomy (CRC) was possible in 37 (69.8%) of the 53 patients who underwent surgery. On univariate analysis, thickness of gallbladder wall 10 mm or more (p <  0.0...
Source: Indian Journal of Surgical Oncology - April 8, 2024 Category: Cancer & Oncology Source Type: research

Isolated Limb Perfusion for Extremity Soft Tissue Sarcoma and Malignant Melanoma
AbstractIsolated limb perfusion (ILP) is a regional chemotherapy technique used in the treatment of locally advanced or unresectable extremity soft tissue sarcoma (ESTS) or malignant melanoma (MM) of the limbs. It allows for high concentrations of chemotherapeutic agents to be perfused in the limb while minimising the risk of systemic side-effects. While the technique has been utilized for decades, the role of ILP has evolved as other treatment strategies have become available. Current indications for ILP in sarcoma include induction in unresectable ESTS to allow for future definitive limb preservation procedures  as well...
Source: Indian Journal of Surgical Oncology - April 8, 2024 Category: Cancer & Oncology Source Type: research

Osteosarcoma of Mandible — A Case Report
AbstractAfter plasma cell neoplasia, osteosarcoma is the most common primary bone tumor which accounts for 20% of all sarcomas. A malignant tumor is characterized by the formation of bone or osteoid by tumor cells. Long bones are the most common site of involvement. In the jaw bones, approximately 5% of involvement with an incidence of 1 in 1.5 million persons per year. It develops in a broad range of ages but is more common in the third and fourth decades, slightly more often in the mandible than in the maxilla. In this case report, a 24-year-old male patient reported a mass in the left mandible for the past 1  week whic...
Source: Indian Journal of Surgical Oncology - April 3, 2024 Category: Cancer & Oncology Source Type: research

Efficacy of Lapatinib Plus Capecitabine After TDM-1 in HER2-Positive Metastatic Breast Cancer Patients
This study evaluated the efficacy and tolerability of the lapatinib plus capecitabine combination after TDM-1 in HER2-positive metastatic breast cancer patients. We retrospectively evaluated the HER2-positive metastatic breast cancer patients ’ data. The patients who progressed after trastuzumab-based chemotherapy and TDM-1 were included in the study. We used the Kaplan–Meier for survival analysis. Eighteen patients were involved in the study. The average age was 48 (range 31–65). De novo metastatic patient’s number was 5 (27.8%) . The most common metastatic sites were liver (50%), lung (44.4%), and brain (44.4%), ...
Source: Indian Journal of Surgical Oncology - April 1, 2024 Category: Cancer & Oncology Source Type: research

Rechallenge of Trastuzumab-based Therapy in HER2-Positive Breast Cancer Patients who Progressed Under TDM-1
This study showed that rechallenge trastuzumab-based therapy was effective and good-tolerated in heavily pretreated patients who had progressed under TDM-1. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - April 1, 2024 Category: Cancer & Oncology Source Type: research

Flow-Through Radial Artery Forearm Flap for Tongue Revascularization After Excision of Base of Tongue Malignancies
We report here two cases of base of tongue excision for which free flow-through radial forearm flap was used to reconstruct the tongue defect as well as salvage the remaining part of ischemic tongue. This technique can be effectively considered in selected cases of vascular compromise due to lingual vessel sacrifice to preserve the cancer-free anterior native tongue tissue with improved functional outcomes. (Source: Indian Journal of Surgical Oncology)
Source: Indian Journal of Surgical Oncology - March 26, 2024 Category: Cancer & Oncology Source Type: research

Cartilaginous Transdifferentiation in Melanoma: A Diagnostic Challenge
AbstractMalignant melanoma  is a formidable tumor originating from melanocytes of neural crest origin, found in various anatomical locations, primarily in the skin, followed by the eyes and mucosal membranes. This tumor stands out due to its remarkable phenotypic diversity. Transdifferentiation, the process of differentiatio n into cell lineages other than the one from which the tumor originated, and phenotypic plasticity, characterized by changes in behavior, morphology, and physiology in response to different environmental conditions, can make melanoma a diagnostic conundrum for unwary pathologists. In this case repor t...
Source: Indian Journal of Surgical Oncology - March 26, 2024 Category: Cancer & Oncology Source Type: research