Bridging current knowledge gap: better primary colorectal cancer prevention in people living with metabolic dysfunction-associated steatotic liver
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - April 30, 2024 Category: Emergency Medicine Source Type: research

Ecology of emergency care in lower-tier healthcare providers in Ghana: an empirical data-driven Bayesian network analytical approach
This study aimed to assess the emergency care preparedness and readiness of primary healthcare providers using a robust evaluation approach. A multicentre retrospective cross-sectional study was conducted on  460 healthcare facilities  using the standardised Health Facilities Emergency Preparedness Assessment Tool (HeFEPAT). Data were analysed via Bayesian Belief network. Emergency preparedness was associated with facility location, type, ownership, and in-charge personnel. Over 70% of facilities lacked specialised emergency/critical care personnel. Although 65% of in-charges reported protocol knowledge, only 7.8% c...
Source: Internal and Emergency Medicine - April 29, 2024 Category: Emergency Medicine Source Type: research

Chinese authors are overrepresented in medical articles retracted for fake peer review or paper mill
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - April 29, 2024 Category: Emergency Medicine Source Type: research

Site and duration of abdominal pain discriminate symptomatic uncomplicated diverticular disease from previous diverticulitis patients
AbstractAbdominal pain in patients with diverticular disease (DD) can be challenging in clinical practice. Patients with symptomatic uncomplicated diverticular disease (SUDD) and patients with a previous acute diverticulitis (PD) may share a similar clinical pattern, difficult to differentiate from irritable bowel syndrome (IBS). We used standardized questionnaires for DD (short and long lasting abdominal pain) and IBS (following Rome III Criteria) to assess clinical features of abdominal pain, in terms of presence, severity and length, in SUDD and PD patients. One hundred and forty-eight SUDD and 118 PD patients completed...
Source: Internal and Emergency Medicine - April 27, 2024 Category: Emergency Medicine Source Type: research

Fasting hyperglycaemia and fatty liver drive colorectal cancer: a retrospective analysis in 1145 patients
ConclusionMASLD and increased FPG may play a role in the clinical background of CRC, bringing to light the fascinating possibility of a reversed gut –liver axis communication in the pathogenesis of CRC. Thus, the use of non-invasive scores of fatty liver may be helpful to predict the risk of CRC and serve as novel prognostic factors for prevention and therapeutic strategies. (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - April 26, 2024 Category: Emergency Medicine Source Type: research

Multidimensional versus unidimensional pain scales for the assessment of analgesic requirement in the emergency department: a systematic review
AbstractPain is a multidimensional experience, potentially rendering unidimensional pain scales inappropriate for assessment. Prior research highlighted their inadequacy as reliable indicators of analgesic requirement. This systematic review aimed to compare multidimensional with unidimensional pain scales in assessing analgesic requirements in the emergency department (ED). Embase, Medline, CINAHL, and PubMed Central were searched to identify ED studies utilizing both unidimensional and multidimensional pain scales. Primary outcome was desire for analgesia. Secondary outcomes were amount of administered analgesia and pati...
Source: Internal and Emergency Medicine - April 25, 2024 Category: Emergency Medicine Source Type: research

Role of triglyceride-glucose index in metabolic assessment of sarcoidosis patients
AbstractSarcoidosis is a rare granulomatous disease that can affect any organ. It leads to an increased risk of metabolic syndrome and insulin resistance, due to biochemical pathways involved in low-grade inflammation in both diseases. The aim of our retrospective case –control study was to evaluate the utility of triglyceride-glucose (TyG) index, a surrogate of insulin resistance, for metabolic assessment of sarcoidosis patients. A cohort of 90 sarcoidosis patients and a cohort of 90 control subjects were enrolled. Clinical, anamnestic, and biochemical data wer e collected. Results showed that TyG index values were high...
Source: Internal and Emergency Medicine - April 24, 2024 Category: Emergency Medicine Source Type: research

A COVID-19 specific multiparametric and ECG-based score for the prediction of in-hospital mortality: ELCOVID score
AbstractWe aimed to develop and validate a COVID-19 specific scoring system, also including some ECG features, to predict all-cause in-hospital mortality at admission. Patients were retrieved from the ELCOVID study (ClinicalTrials.govidentifier: NCT04367129), a prospective, multicenter Italian study enrolling COVID-19 patients between May to September 2020. For the model validation, we randomly selected two-thirds of participants to create a derivation dataset and we used the remaining one-third of participants as the validation set. Over the study period, 1014 hospitalized COVID-19 patients (mean age 74  years, 61% males...
Source: Internal and Emergency Medicine - April 23, 2024 Category: Emergency Medicine Source Type: research

Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review. Comment
AbstractIn this letter to the Editor, the author reports his comment on the review article entitled “Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review”, published in this Journal. (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - April 23, 2024 Category: Emergency Medicine Source Type: research

Treating colonic diverticula with rifaximin: a call to action
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - April 20, 2024 Category: Emergency Medicine Source Type: research

Metabolic risks remain a serious threat to cardiovascular disease: findings from the Global Burden of Disease Study 2019
AbstractMetabolic factors are major and controllable risk factors for cardiovascular diseases (CVD), and few studies have described this burden. We aim to assess it from 1990 to 2019 and predict the trends through 2034. Global Burden of Disease (GBD) provides data on sex, age, and socio-demographic index (SDI) levels. Numbers, age-standardized death rates (ASDR) and estimated annual percentage change (EAPC) were used. Future trends were estimated by NORDPRED model. The deaths cases of metabolic-related CVD increased from 8.61 million (95% UI: 7.91 –9.29) to 13.71 million (95% UI: 12.24–14.94) globally. The ASDR continu...
Source: Internal and Emergency Medicine - April 20, 2024 Category: Emergency Medicine Source Type: research

Inpatient opioid withdrawal: a qualitative study of the patient perspective
In this study, we aimed to capture the patient-reported experience of opioid withdrawal during hospitalization and its impact on the desire to continue treatment for opioid use disorder after discharge. We performed a single-center qualitative study involving semi-structured interviews of hospitalized patients with opioid use disorder (OUD) experiencing opioid withdrawal. Investigators conducted in-person interviews utilizing a combination of open-ended and dichotomous questions. Interview transcripts were then analyzed with open coding for emergent themes. Nineteen interviews were performed. All participants were linked t...
Source: Internal and Emergency Medicine - April 20, 2024 Category: Emergency Medicine Source Type: research

When pulmonary arterial hypertension complicates connective tissue diseases: we still have not found what we are looking for
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - April 18, 2024 Category: Emergency Medicine Source Type: research

Evaluation of use and identification of predictive factors for nonuse of peripheral venous catheters in the emergency department
AbstractThe placement of peripheral venous catheters (PVC) is a frequent procedure in the emergency department (ED), which exposes patients to complications (hematoma, fluid leakage, phlebitis, edema, infection), increases hemolysis of blood samples, is time-consuming and costly. The main aim of this study is to analyze the rate of PVC nonuse in the ED and to identify predictive factors of their nonuse. This prospective single-center observational study was conducted in the ED of the Saint-Antoine Hospital in Paris, France between February and March 2022. Adult patients receiving a PVC were included. In addition to demogra...
Source: Internal and Emergency Medicine - April 17, 2024 Category: Emergency Medicine Source Type: research

High early mortality rate among Nursing Home residents treated by Mobile Intensive Care Unit
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - April 17, 2024 Category: Emergency Medicine Source Type: research