The Characteristics and Management Considerations of Late-onset Rheumatoid Arthritis
Intern Med. 2024 May 2. doi: 10.2169/internalmedicine.3786-24. Online ahead of print.NO ABSTRACTPMID:38692913 | DOI:10.2169/internalmedicine.3786-24 (Source: Internal Medicine)
Source: Internal Medicine - May 1, 2024 Category: Internal Medicine Authors: Ryusuke Yoshimi Hideaki Nakajima Source Type: research

Positive anti-nuclear antibody in patients with polyclonal hypergammaglobulinemia suggests the presence of multiple distinct comorbidities
Conclusion These results establish a previously underappreciated unique immunological state of multimorbidity in PHGG and indicate that the gamma-globulin levels and ANAs could serve as markers for the clinical assessment of comorbidities in PHGG.PMID:38692914 | DOI:10.2169/internalmedicine.3594-24 (Source: Internal Medicine)
Source: Internal Medicine - May 1, 2024 Category: Internal Medicine Authors: Yasutaka Masuda Ken Morita Mineo Kurokawa Source Type: research

A preliminary survey of rheumatologists on the management of late-onset rheumatoid arthritis in Japan
Conclusion This preliminary survey highlighted various rheumatologists' perspectives regarding the management of LORA.PMID:38692915 | DOI:10.2169/internalmedicine.3288-23 (Source: Internal Medicine)
Source: Internal Medicine - May 1, 2024 Category: Internal Medicine Authors: Satoshi Takanashi Yuko Kaneko Yutaka Kawahito Takashi Kida Takahiko Sugihara Toshihisa Kojima Ryozo Harada Michinori Ishitoku Shintaro Hirata Motomu Hashimoto Toshihiko Hidaka Asami Abe Hajime Ishikawa Hiromu Ito Mitsumasa Kishimoto Kazuo Matsui Toshihiro Source Type: research

Chronic bromine intoxication complicated with Fanconi syndrome: A case report
In this report, we describe a unique case of an 80-year-old woman who developed chronic bromine poisoning due to the prolonged ingestion of over-the-counter (OTC) medication containing bromovalerylurea (BVU), thus leading to the onset of drug-induced partial Fanconi syndrome and resultant osteomalacia. The patient's condition improved following the cessation of bromide intake. This case highlights the potential risks of chronic BVU exposure and the importance of caution regarding the use of OTC medications containing BVU.PMID:38692916 | DOI:10.2169/internalmedicine.3128-23 (Source: Internal Medicine)
Source: Internal Medicine - May 1, 2024 Category: Internal Medicine Authors: Yusuke Makio Taku Harada Kazushi Yamasato Toshiyuki Nakanishi Mori Nakai Source Type: research

Status epilepticus with unilateral brain edema in COVID-19
Intern Med. 2024 May 2. doi: 10.2169/internalmedicine.3080-23. Online ahead of print.NO ABSTRACTPMID:38692917 | DOI:10.2169/internalmedicine.3080-23 (Source: Internal Medicine)
Source: Internal Medicine - May 1, 2024 Category: Internal Medicine Authors: Yasuhiro Aso Teruaki Masuda Noriyuki Kimura Etsuro Matsubara Source Type: research

The Characteristics and Management Considerations of Late-onset Rheumatoid Arthritis
Intern Med. 2024 May 2. doi: 10.2169/internalmedicine.3786-24. Online ahead of print.NO ABSTRACTPMID:38692913 | DOI:10.2169/internalmedicine.3786-24 (Source: Internal Medicine)
Source: Internal Medicine - May 1, 2024 Category: Internal Medicine Authors: Ryusuke Yoshimi Hideaki Nakajima Source Type: research

Positive anti-nuclear antibody in patients with polyclonal hypergammaglobulinemia suggests the presence of multiple distinct comorbidities
Conclusion These results establish a previously underappreciated unique immunological state of multimorbidity in PHGG and indicate that the gamma-globulin levels and ANAs could serve as markers for the clinical assessment of comorbidities in PHGG.PMID:38692914 | DOI:10.2169/internalmedicine.3594-24 (Source: Internal Medicine)
Source: Internal Medicine - May 1, 2024 Category: Internal Medicine Authors: Yasutaka Masuda Ken Morita Mineo Kurokawa Source Type: research

A preliminary survey of rheumatologists on the management of late-onset rheumatoid arthritis in Japan
Conclusion This preliminary survey highlighted various rheumatologists' perspectives regarding the management of LORA.PMID:38692915 | DOI:10.2169/internalmedicine.3288-23 (Source: Internal Medicine)
Source: Internal Medicine - May 1, 2024 Category: Internal Medicine Authors: Satoshi Takanashi Yuko Kaneko Yutaka Kawahito Takashi Kida Takahiko Sugihara Toshihisa Kojima Ryozo Harada Michinori Ishitoku Shintaro Hirata Motomu Hashimoto Toshihiko Hidaka Asami Abe Hajime Ishikawa Hiromu Ito Mitsumasa Kishimoto Kazuo Matsui Toshihiro Source Type: research

Chronic bromine intoxication complicated with Fanconi syndrome: A case report
In this report, we describe a unique case of an 80-year-old woman who developed chronic bromine poisoning due to the prolonged ingestion of over-the-counter (OTC) medication containing bromovalerylurea (BVU), thus leading to the onset of drug-induced partial Fanconi syndrome and resultant osteomalacia. The patient's condition improved following the cessation of bromide intake. This case highlights the potential risks of chronic BVU exposure and the importance of caution regarding the use of OTC medications containing BVU.PMID:38692916 | DOI:10.2169/internalmedicine.3128-23 (Source: Internal Medicine)
Source: Internal Medicine - May 1, 2024 Category: Internal Medicine Authors: Yusuke Makio Taku Harada Kazushi Yamasato Toshiyuki Nakanishi Mori Nakai Source Type: research

Status epilepticus with unilateral brain edema in COVID-19
Intern Med. 2024 May 2. doi: 10.2169/internalmedicine.3080-23. Online ahead of print.NO ABSTRACTPMID:38692917 | DOI:10.2169/internalmedicine.3080-23 (Source: Internal Medicine)
Source: Internal Medicine - May 1, 2024 Category: Internal Medicine Authors: Yasuhiro Aso Teruaki Masuda Noriyuki Kimura Etsuro Matsubara Source Type: research

Immune Checkpoint Inhibitor Myotoxicities: An Autoimmune Perspective
Intern Med. 2024 Apr 23. doi: 10.2169/internalmedicine.3700-24. Online ahead of print.NO ABSTRACTPMID:38658335 | DOI:10.2169/internalmedicine.3700-24 (Source: Internal Medicine)
Source: Internal Medicine - April 24, 2024 Category: Internal Medicine Authors: Kazuko Tajiri Source Type: research

Primary Extranodal Diffuse Large B-cell Lymphoma Presenting in the Lips: A Case Report and Literature Review
Intern Med. 2024 Apr 23. doi: 10.2169/internalmedicine.3675-24. Online ahead of print.ABSTRACTApproximately 30-40% of malignant lymphomas are classified as diffuse large B-cell lymphoma (DLBCL), with 30% of DLBCL cases manifesting as extranodal lymphomas. Among these extranodal DLBCLs, primary DLBCL in oral lesions, particularly in the lips, is rare. While the treatment methods, chemotherapy assessment, and prognosis for nodal and extranodal DLBCLs are generally similar, diagnostic challenges can lead to delayed therapeutic intervention. We herein present a recent case of primary extranodal DLBCL in the lips that was swift...
Source: Internal Medicine - April 24, 2024 Category: Internal Medicine Authors: Hideshige Seki Ken Morita Megumi Yasunaga Masanori Toho Hiroaki Maki Mineo Kurokawa Source Type: research

Fatal systemic capillary leak syndrome in a patient with a COVID-19 infection
Intern Med. 2024 Apr 23. doi: 10.2169/internalmedicine.3637-24. Online ahead of print.ABSTRACTA 29-year-old Japanese woman was admitted to our hospital with a fever, cardiogenic shock, and cardiac arrest. Laboratory data indicated multiple organ failure in addition to hemoconcentration, hypoalbuminemia, and myocardial damage. The coronary angiography findings were normal, and fulminant myocarditis was suspected. Venoarterial peripheral extracorporeal membrane oxygenation and an Impella CP left ventricular assist device were initiated, along with the administration of positive inotropic agents. However, hypovolemic shock an...
Source: Internal Medicine - April 24, 2024 Category: Internal Medicine Authors: Hiroaki Kawano Masataka Umeda Tomohiro Honda Ryosuke Iwasaki Shinji Okano Ryohei Akashi Tomohiro Koga Koichi Izumikawa Atsushi Kawakami Koji Maemura Source Type: research

Cases: Decompensated Heart Failure Secondary to Hypopituitarism in an Elderly Patient
Intern Med. 2024 Apr 23. doi: 10.2169/internalmedicine.3491-24. Online ahead of print.ABSTRACTHypopituitarism is difficult to diagnose because of its non-specific symptoms, especially in the presence of comorbidities. A 77-year-old woman with worsening anorexia and exertional dyspnea was initially diagnosed with decompensated dry cold-type heart failure. Hormonal laboratory tests indicated secondary hypothyroidism as a part of the evaluation of heart failure. Furthermore, pituitary magnetic resonance imaging revealed thickening of the pituitary stalk and a loss of signal intensity in the posterior pituitary, thus suggestin...
Source: Internal Medicine - April 24, 2024 Category: Internal Medicine Authors: Yumiko Yoshino Yoshihiro Harano Toshiro Shibata Junko Shiroko Source Type: research

Early gastric cancer accompanying Gastritis cystica profunda with a Giant cyst
Intern Med. 2024 Apr 23. doi: 10.2169/internalmedicine.3460-24. Online ahead of print.NO ABSTRACTPMID:38658339 | DOI:10.2169/internalmedicine.3460-24 (Source: Internal Medicine)
Source: Internal Medicine - April 24, 2024 Category: Internal Medicine Authors: Hironao Matsumoto Takeshi Yamashina Masaaki Shimatani Source Type: research