Potential Efficacy of Janus Kinase Inhibitors in the Treatment of a Patient With Coexisting Peripheral and Axial Spondyloarthritis and Ulcerative Colitis
J Rheumatol. 2024 May 1:jrheum.2024-0055. doi: 10.3899/jrheum.2024-0055. Online ahead of print.ABSTRACTTumor necrosis factor inhibitors are effective and recommended in treating patients with coexisting spondyloarthritis (SpA) and ulcerative colitis (UC); however, the evidence of their superiority over other drugs is insufficient.1 Although Janus kinase inhibitors (JAKi) have shown effectiveness in treating UC and psoriatic arthritis, there are no reports of treating coexisting SpA and UC with JAKi monotherapy.PMID:38692666 | DOI:10.3899/jrheum.2024-0055 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Sho Ishigaki Nobuhiko Kajio Noritada Yoshikawa Hiroaki Taguchi Source Type: research
Interpersonal process of dyadic coping in rheumatoid arthritis: a perspective from the Australian Rheumatology Association Database (ARAD)
CONCLUSION: Participants and spouse's own views of supportive and negative dyadic coping they receive intimately affects their psychological distress and relationship quality. Also, having a partner with rheumatoid arthritis also seemed to impact the spouse especially when there was a negative dyadic coping pattern.PMID:38692667 | DOI:10.3899/jrheum.2023-0664 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Manasi M Mittinty Murthy N Mittinty Rachelle Buchbinder Marissa Lassere Vibhasha Chand Samuel Whittle Lyn March Catherine Hill Source Type: research
Sex-related differences in dispensation of rheumatic medications in older patients with inflammatory arthritis: A population-based study
CONCLUSION: This study did not identify any sex difference in use of DMARDs among older RA and PsA patients. Reasons for the higher use of opioids and NSAIDs among female RA patients warrants further research.PMID:38692668 | DOI:10.3899/jrheum.2023-1148 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Sanjana Tarannum Jessica Widdifield C Fangyun Wu Sindhu R Johnson Paula Rochon Lihi Eder Source Type: research
The Impact of Rheumatoid Arthritis on First Nations and How We Can Work With Communities to Prevent It
J Rheumatol. 2024 May 1:jrheum.2024-0369. doi: 10.3899/jrheum.2024-0369. Online ahead of print.ABSTRACTRheumatoid arthritis (RA) is prevalent in many Indigenous North American First Nations (FN) and tends to be seropositive, familial, and disabling, as well as associated with highly unfavorable outcomes such as early mortality. The risk of developing RA is based on a perfect storm of gene-environment interactions underpinning this risk. The gene-environment interactions include a high frequency of shared epitope encoding HLA alleles, particularly HLA-DRB1*1402, in the background population, and prevalent predisposing envir...
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Hani El-Gabalawy Source Type: research
Circulating interleukin 17A and other inflammatory proteins may predict cardiovascular disease in early rheumatoid arthritis
CONCLUSION: Circulating IL-17A at RA diagnosis predicted future CVD, although we cannot exclude that this finding is due to multiple testing. The association was independent of traditional CVD risk factors, and of ESR at the time of diagnosis. Furthermore, OPG may be a predictor of CVD. We also identified some novel potential biomarkers for CVD in RA.PMID:38692670 | DOI:10.3899/jrheum.2023-1078 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Emil Rydell Lennart T H Jacobsson Carl Turesson Source Type: research
Potential Efficacy of Janus Kinase Inhibitors in the Treatment of a Patient With Coexisting Peripheral and Axial Spondyloarthritis and Ulcerative Colitis
J Rheumatol. 2024 May 1:jrheum.2024-0055. doi: 10.3899/jrheum.2024-0055. Online ahead of print.ABSTRACTTumor necrosis factor inhibitors are effective and recommended in treating patients with coexisting spondyloarthritis (SpA) and ulcerative colitis (UC); however, the evidence of their superiority over other drugs is insufficient.1 Although Janus kinase inhibitors (JAKi) have shown effectiveness in treating UC and psoriatic arthritis, there are no reports of treating coexisting SpA and UC with JAKi monotherapy.PMID:38692666 | DOI:10.3899/jrheum.2024-0055 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Sho Ishigaki Nobuhiko Kajio Noritada Yoshikawa Hiroaki Taguchi Source Type: research
Interpersonal process of dyadic coping in rheumatoid arthritis: a perspective from the Australian Rheumatology Association Database (ARAD)
CONCLUSION: Participants and spouse's own views of supportive and negative dyadic coping they receive intimately affects their psychological distress and relationship quality. Also, having a partner with rheumatoid arthritis also seemed to impact the spouse especially when there was a negative dyadic coping pattern.PMID:38692667 | DOI:10.3899/jrheum.2023-0664 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Manasi M Mittinty Murthy N Mittinty Rachelle Buchbinder Marissa Lassere Vibhasha Chand Samuel Whittle Lyn March Catherine Hill Source Type: research
Sex-related differences in dispensation of rheumatic medications in older patients with inflammatory arthritis: A population-based study
CONCLUSION: This study did not identify any sex difference in use of DMARDs among older RA and PsA patients. Reasons for the higher use of opioids and NSAIDs among female RA patients warrants further research.PMID:38692668 | DOI:10.3899/jrheum.2023-1148 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Sanjana Tarannum Jessica Widdifield C Fangyun Wu Sindhu R Johnson Paula Rochon Lihi Eder Source Type: research
The Impact of Rheumatoid Arthritis on First Nations and How We Can Work With Communities to Prevent It
J Rheumatol. 2024 May 1:jrheum.2024-0369. doi: 10.3899/jrheum.2024-0369. Online ahead of print.ABSTRACTRheumatoid arthritis (RA) is prevalent in many Indigenous North American First Nations (FN) and tends to be seropositive, familial, and disabling, as well as associated with highly unfavorable outcomes such as early mortality. The risk of developing RA is based on a perfect storm of gene-environment interactions underpinning this risk. The gene-environment interactions include a high frequency of shared epitope encoding HLA alleles, particularly HLA-DRB1*1402, in the background population, and prevalent predisposing envir...
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Hani El-Gabalawy Source Type: research
Circulating interleukin 17A and other inflammatory proteins may predict cardiovascular disease in early rheumatoid arthritis
CONCLUSION: Circulating IL-17A at RA diagnosis predicted future CVD, although we cannot exclude that this finding is due to multiple testing. The association was independent of traditional CVD risk factors, and of ESR at the time of diagnosis. Furthermore, OPG may be a predictor of CVD. We also identified some novel potential biomarkers for CVD in RA.PMID:38692670 | DOI:10.3899/jrheum.2023-1078 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Emil Rydell Lennart T H Jacobsson Carl Turesson Source Type: research
ASDAS-CRP and ASDAS-ESR cut-offs for disease activity states in axial spondyloarthritis - Are they interchangeable?
CONCLUSION: We estimated the optimal ASDAS-ESR values corresponding to the established ASDAS-CRP cut-off values. However, applying the estimated cut-offs did not increase the level of agreement between ASDAS-ESR and ASDAS-CRP disease activity states to a relevant degree. Our findings did not provide evidence to reject the established cut-off values for ASDAS-ESR.PMID:38621792 | DOI:10.3899/jrheum.2023-1217 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Stylianos Georgiadis Lykke Midtb øll Ørnbjerg Brigitte Michelsen Tore K Kvien Daniela Di Giuseppe Johan K Wallman Jakub Z ávada Sella A Provan Eirik Klami Kristianslund Ana Maria Rodrigues Maria Jos é Santos Žiga Rotar Katja Perdan Pirkmajer Dan Nord Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
Patient-Initiated Follow-Up
J Rheumatol. 2024 Apr 15:jrheum.2024-0302. doi: 10.3899/jrheum.2024-0302. Online ahead of print.ABSTRACTIn the contemporary healthcare climate, we are acutely aware that our resources are finite. This is particularly pertinent in government-funded healthcare settings, where clinical teams often face the challenge of meeting increasing patient demand with static or dwindling capacity.1-4.PMID:38621794 | DOI:10.3899/jrheum.2024-0302 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Edward Alveyn James Galloway Laura C Coates Source Type: research
Fibromyalgia and the Difficult Synthesis
J Rheumatol. 2024 Apr 15:jrheum.2024-0321. doi: 10.3899/jrheum.2024-0321. Online ahead of print.ABSTRACTThe pathophysiological uncertainties in fibromyalgia (FM) mean that its diagnosis, to this day, remains a strictly clinical exercise. The physician's evaluation of symptoms is therefore of fundamental importance both for the correct diagnostic framing of the patient and also for guiding a personalized therapeutic approach.1.PMID:38621795 | DOI:10.3899/jrheum.2024-0321 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Marco Di Carlo Benedetta Bianchi Fausto Salaffi Source Type: research
Knowledge of and stated adherence to the 2020 ACR Guideline for Gout Management: Results of a survey of US rheumatologists
CONCLUSION: The self-reported practice of the surveyed US rheumatologists was generally concordant with the 2020 ACR Guideline for the Management of Gout. However, there were gaps in guideline knowledge and stated adherence among rheumatologists, mainly concerning the dosing of treatment regimens.PMID:38621796 | DOI:10.3899/jrheum.2023-0981 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Naomi Schlesinger Michael H Pillinger Peter E Lipsky Source Type: research
