USPSTF Recommendation: Screening for Breast Cancer
This 2024 Recommendation Statement from the US Preventive Services Task Force recommends biennial screening mammography for women aged 40 to 74 years (B recommendation) and concludes that evidence is insufficient to assess the balance of benefits and harms of screening mammography in women 75 years or older (I statement) and of screening using ultrasonography or MRI in women with dense breasts on a negative mammogram (I statement). (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 30, 2024 Category: General Medicine Source Type: research

USPSTF Review: Screening for Breast Cancer
This systematic review to support a 2024 US Preventive Services Task Force Recommendation Statement summarizes published evidence on the benefits and harms of screening for breast cancer in adult females. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 30, 2024 Category: General Medicine Source Type: research

USPSTF Report: Collaborative Modeling to Compare Breast Cancer Screening Strategies
This modeling study uses Cancer Intervention and Surveillance Modeling Network models and national data on breast cancer incidence, mammography performance, treatment effects, and other-cause mortality in US women without previous cancer diagnoses to estimate outcomes of various mammography screening strategies. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 30, 2024 Category: General Medicine Source Type: research

Screening for Breast Cancer
In this JAMA Patient Page, the US Preventive Services Task Force provides a guide to screening for breast cancer. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 30, 2024 Category: General Medicine Source Type: research

Toward More Equitable Breast Cancer Outcomes
In its revised Recommendation Statement, the US Preventive Services Task Force (USPSTF) now recommends that all women undergo routine breast cancer screening every other year beginning at age 40 years. This is an adjustment from the 2016 recommendation for all women to start at age 50 and for women aged 40 to 49 to engage in individualized decision-making and part of an overarching aim to increase earlier detection of breast cancer and address inequalities in breast cancer mortality, especially among Black women. Additionally, the task force, in acknowledgment of evolving technology, updated the recommended primary screeni...
Source: JAMA - Journal of the American Medical Association - April 30, 2024 Category: General Medicine Source Type: research

Addition of Name to List of Investigators
This article was corrected online. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 30, 2024 Category: General Medicine Source Type: research

At-Home Diagnostics Solutions for Chlamydia and Gonorrhea
This Viewpoint discusses the US Food and Drug Administration ’s authorization of marketing an at-home testing system for chlamydia and gonorrhea as a good first step in boosting access to screening and treatment and in reducing infection rates. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 29, 2024 Category: General Medicine Source Type: research

Aspirin vs Placebo as Adjuvant Therapy for Breast Cancer
This study examines the potential benefits of aspirin as adjuvant therapy for survivors of early breast cancer. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 29, 2024 Category: General Medicine Source Type: research

Outcomes Following Localized Prostate Cancer Treatment —Reply
In Reply In response to our recent article, Drs Huang and Ding question the validity of using questionnaires to assess sexual function. While a patient ’s responses are subjective (ie, indicating how their function seems to them rather than it being measured more objectively), the use of standardized, validated instruments for patient-reported outcomes remains the standard for both clinical and research purposes. Furthermore, any subjectivity-bas ed misclassification would be expected to be nondifferential and, therefore, should not affect our comparative results. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 29, 2024 Category: General Medicine Source Type: research

Outcomes Following Localized Prostate Cancer Treatment
To the Editor In a recent article that compared adverse outcomes of localized prostate cancer treatment modalities, persistent urinary incontinence after radical prostatectomy was highlighted as a significant difference compared with other therapeutic options. However, the authors overlooked the existence of safe and effective curative options for postprostatectomy incontinence management. When pelvic floor muscle training after prostatic surgery is ineffective for postprostatectomy incontinence, various surgical options such as the artificial urinary sphincter or minimally invasive alternatives such as periurethral balloo...
Source: JAMA - Journal of the American Medical Association - April 29, 2024 Category: General Medicine Source Type: research

Outcomes Following Localized Prostate Cancer Treatment
To the Editor A recent study reported approximately 10-year follow-up data on functional outcomes of patients after treatment for localized prostate cancer, providing essential evidence-based medical evidence for clinical decision-making. We have 2 concerns regarding the data analyses on sexual function after radical prostatectomy. First, apart from androgen deprivation therapy, the potential influence of salvage radiotherapy on sexual function also needs to be considered because this therapy is frequently used after radical prostatectomy in clinical settings, especially among patients with unfavorable-prognosis prostate c...
Source: JAMA - Journal of the American Medical Association - April 29, 2024 Category: General Medicine Source Type: research

Global Production of Active Pharmaceutical Ingredients for US Generic Drugs Experiencing Shortages
This study evaluates the characteristics of generic active pharmaceutical ingredients (APIs) used to manufacture drugs with shortages in the US and facilities producing APIs worldwide. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 29, 2024 Category: General Medicine Source Type: research

Aspirin Use and Management of Breast Cancer
The Alliance trial led by Chen and colleagues and published in this issue of JAMA addresses an important topic in the management of breast cancer: can daily use of 300 mg of aspirin improve invasive disease –free survival among persons with a diagnosis of nonmetastatic, high-risk breast cancer? The answer is a fairly definitive no based on prespecified futility rules in a rigorous phase 3, randomized, placebo-controlled, double-blind trial. The trial (A011502) enrolled 3020 persons (3004 women [99.5% ] and 16 men [0.5%]) from 534 academic and community sites across the US and Canada. Although the trial was planned for 5 ...
Source: JAMA - Journal of the American Medical Association - April 29, 2024 Category: General Medicine Source Type: research

Patients with Long COVID May Tolerate Cautious Exercise Rehabilitation
This Medical News story discusses a clinical trial that tested symptom-guided exercise for patients with long COVID and postexertional malaise. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 26, 2024 Category: General Medicine Source Type: research

WHO Launches Broad Coronavirus Surveillance Network
A new initiative, known as the Coronavirus Network or CoViNet, will bring together experts in human, animal, and environmental health to monitor known coronaviruses such as SARS-CoV-2 and Middle East respiratory syndrome coronavirus, or MERS-CoV, the World Health Organization (WHO) said in a recent statement. CoViNet will also aid in the early detection of novel coronaviruses. The network involves 36 laboratories across 21 countries, including the US Centers for Disease Control and Prevention. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 26, 2024 Category: General Medicine Source Type: research