Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
CONCLUSION: An individualized risk-based approach is recommended. Our study suggests that lymphovascular invasion may be associated with a higher risk of persistence/recurrence and should therefore be considered for decision making in children and adolescents with PTC.PMID:38683018 | DOI:10.4274/jcrpe.galenos.2024.2024-1-25 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Francisca Marques Puga Laura Correia In ês Vieira Joana Serra Caetano Rita Cardoso Isabel Dinis Alice Mirante Source Type: research

Predictors and Trends of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes Mellitus in Malaysian Children
CONCLUSION: DKA rates at initial diagnosis of T1DM in Malaysian children are high and severe DKA accounts for a significant burden. Though misdiagnosis and age ≥5 years are predictors of DKA, misdiagnosis can be improved through awareness and education. The lack of downward trends in DKA and severe DKA highlights the urgency to develop measures to curb its rates.PMID:38683019 | DOI:10.4274/jcrpe.galenos.2024.2024-1-8 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Meenal Mavinkurve Nurul Hanis Ramzi Muhammad Yazid Bin Jalaludin Nurshadia Samingan Azriyanti Anuar Zaini Source Type: research

The Relationship Between Sleep Quality, Sleep Duration, Social Jet Lag and Obesity in Adolescents
CONCLUSION: Adolescents with obesity reveal poorer sleep quality and a longer duration of SJL compared to adolescents with normal-weight. Moreover, increased SJL was linked to an increase in BMI. Maintaining good sleep quality and less exposure to SJL may help reduce the risk of obesity.PMID:38683020 | DOI:10.4274/jcrpe.galenos.2024.2024-2-2 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Funda Y ıldız Melike Zeynep Tu ğrul Aksakal Raif Y ıldız Firdevs Ba ş Source Type: research

Delayed Puberty and Management of Treatment
J Clin Res Pediatr Endocrinol. 2024 Apr 29. doi: 10.4274/jcrpe.galenos.2024.2024-2-7. Online ahead of print.ABSTRACTDelayed puberty is defined as the lack of development of secondary sex characteristics in childhood. Based on a review of the literature, delayed puberty can be divided into three main categories: (i) hypergonadotropic hypogonadism (congenital and acquired), (ii) permanent hypogonadotropic hypogonadism (congenital and acquired), and (iii) transient hypogonadotropic hypogonadism [constitutional delay of growth and puberty (CDGP) and functional hypogonadotropic hypogonadism (FHH)]. CDGP is the most common cause...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Ayhan Abac ı Özge Besci Source Type: research

Current Diagnostic Approaches in the Genetic Diagnosis of Disorders of Sex Development
In conclusion, the clinical and genetic diagnosis of DSD is difficult, and molecular genetic diagnosis is often not available. This has psychosocial and health implications for patients and their families. New genetic techniques, especially those targeting the whole genome, may provide a better understanding of DSD through the identification of little-known genetic causes. This review focuses on conventional genetic and next-generation genetic techniques used in the genetic diagnosis of DSD, as well as possible genetic diagnostic techniques and approaches that may be used in routine practice in near future.PMID:38683034 | ...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Deniz Özalp Kızılay Samim Özen Source Type: research

Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
CONCLUSION: An individualized risk-based approach is recommended. Our study suggests that lymphovascular invasion may be associated with a higher risk of persistence/recurrence and should therefore be considered for decision making in children and adolescents with PTC.PMID:38683018 | DOI:10.4274/jcrpe.galenos.2024.2024-1-25 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Francisca Marques Puga Laura Correia In ês Vieira Joana Serra Caetano Rita Cardoso Isabel Dinis Alice Mirante Source Type: research

Predictors and Trends of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes Mellitus in Malaysian Children
CONCLUSION: DKA rates at initial diagnosis of T1DM in Malaysian children are high and severe DKA accounts for a significant burden. Though misdiagnosis and age ≥5 years are predictors of DKA, misdiagnosis can be improved through awareness and education. The lack of downward trends in DKA and severe DKA highlights the urgency to develop measures to curb its rates.PMID:38683019 | DOI:10.4274/jcrpe.galenos.2024.2024-1-8 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Meenal Mavinkurve Nurul Hanis Ramzi Muhammad Yazid Bin Jalaludin Nurshadia Samingan Azriyanti Anuar Zaini Source Type: research

The Relationship Between Sleep Quality, Sleep Duration, Social Jet Lag and Obesity in Adolescents
CONCLUSION: Adolescents with obesity reveal poorer sleep quality and a longer duration of SJL compared to adolescents with normal-weight. Moreover, increased SJL was linked to an increase in BMI. Maintaining good sleep quality and less exposure to SJL may help reduce the risk of obesity.PMID:38683020 | DOI:10.4274/jcrpe.galenos.2024.2024-2-2 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Funda Y ıldız Melike Zeynep Tu ğrul Aksakal Raif Y ıldız Firdevs Ba ş Source Type: research

Delayed Puberty and Management of Treatment
J Clin Res Pediatr Endocrinol. 2024 Apr 29. doi: 10.4274/jcrpe.galenos.2024.2024-2-7. Online ahead of print.ABSTRACTDelayed puberty is defined as the lack of development of secondary sex characteristics in childhood. Based on a review of the literature, delayed puberty can be divided into three main categories: (i) hypergonadotropic hypogonadism (congenital and acquired), (ii) permanent hypogonadotropic hypogonadism (congenital and acquired), and (iii) transient hypogonadotropic hypogonadism [constitutional delay of growth and puberty (CDGP) and functional hypogonadotropic hypogonadism (FHH)]. CDGP is the most common cause...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Ayhan Abac ı Özge Besci Source Type: research

Current Diagnostic Approaches in the Genetic Diagnosis of Disorders of Sex Development
In conclusion, the clinical and genetic diagnosis of DSD is difficult, and molecular genetic diagnosis is often not available. This has psychosocial and health implications for patients and their families. New genetic techniques, especially those targeting the whole genome, may provide a better understanding of DSD through the identification of little-known genetic causes. This review focuses on conventional genetic and next-generation genetic techniques used in the genetic diagnosis of DSD, as well as possible genetic diagnostic techniques and approaches that may be used in routine practice in near future.PMID:38683034 | ...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Deniz Özalp Kızılay Samim Özen Source Type: research

Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
CONCLUSION: An individualized risk-based approach is recommended. Our study suggests that lymphovascular invasion may be associated with a higher risk of persistence/recurrence and should therefore be considered for decision making in children and adolescents with PTC.PMID:38683018 | DOI:10.4274/jcrpe.galenos.2024.2024-1-25 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Francisca Marques Puga Laura Correia In ês Vieira Joana Serra Caetano Rita Cardoso Isabel Dinis Alice Mirante Source Type: research

Predictors and Trends of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes Mellitus in Malaysian Children
CONCLUSION: DKA rates at initial diagnosis of T1DM in Malaysian children are high and severe DKA accounts for a significant burden. Though misdiagnosis and age ≥5 years are predictors of DKA, misdiagnosis can be improved through awareness and education. The lack of downward trends in DKA and severe DKA highlights the urgency to develop measures to curb its rates.PMID:38683019 | DOI:10.4274/jcrpe.galenos.2024.2024-1-8 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Meenal Mavinkurve Nurul Hanis Ramzi Muhammad Yazid Bin Jalaludin Nurshadia Samingan Azriyanti Anuar Zaini Source Type: research

The Relationship Between Sleep Quality, Sleep Duration, Social Jet Lag and Obesity in Adolescents
CONCLUSION: Adolescents with obesity reveal poorer sleep quality and a longer duration of SJL compared to adolescents with normal-weight. Moreover, increased SJL was linked to an increase in BMI. Maintaining good sleep quality and less exposure to SJL may help reduce the risk of obesity.PMID:38683020 | DOI:10.4274/jcrpe.galenos.2024.2024-2-2 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Funda Y ıldız Melike Zeynep Tu ğrul Aksakal Raif Y ıldız Firdevs Ba ş Source Type: research

Delayed Puberty and Management of Treatment
J Clin Res Pediatr Endocrinol. 2024 Apr 29. doi: 10.4274/jcrpe.galenos.2024.2024-2-7. Online ahead of print.ABSTRACTDelayed puberty is defined as the lack of development of secondary sex characteristics in childhood. Based on a review of the literature, delayed puberty can be divided into three main categories: (i) hypergonadotropic hypogonadism (congenital and acquired), (ii) permanent hypogonadotropic hypogonadism (congenital and acquired), and (iii) transient hypogonadotropic hypogonadism [constitutional delay of growth and puberty (CDGP) and functional hypogonadotropic hypogonadism (FHH)]. CDGP is the most common cause...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Ayhan Abac ı Özge Besci Source Type: research

Current Diagnostic Approaches in the Genetic Diagnosis of Disorders of Sex Development
In conclusion, the clinical and genetic diagnosis of DSD is difficult, and molecular genetic diagnosis is often not available. This has psychosocial and health implications for patients and their families. New genetic techniques, especially those targeting the whole genome, may provide a better understanding of DSD through the identification of little-known genetic causes. This review focuses on conventional genetic and next-generation genetic techniques used in the genetic diagnosis of DSD, as well as possible genetic diagnostic techniques and approaches that may be used in routine practice in near future.PMID:38683034 | ...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Deniz Özalp Kızılay Samim Özen Source Type: research