Comparative effect of Tai Chi and aerobic exercise on cognitive function in advanced lung cancer survivors with perceived cognitive impairment: a three-arm randomized controlled trial with mediation analysis
ConclusionsTai Chi demonstrated beneficial effects on cognitive function in advanced lung cancer survivors with perceived cognitive impairment. Improvement in cognitive function was mediated by reducing sleep disturbance, fatigue, anxiety, and depression, highlighting the importance of addressing these symptoms in future interventions to improve cognitive function, with anxiety playing a significant role at an earlier stage.Implications for Cancer SurvivorsTai Chi is a potentially safe complementary therapeutic option for managing cognitive impairment in this vulnerable population.Trial registrationClinicalTrials.gov ident...
Source: Journal of Cancer Survivorship - May 1, 2024 Category: Cancer & Oncology Source Type: research
Functional decline in older breast cancer survivors treated with and without chemotherapy and non-cancer controls: results from the Hurria Older PatiEnts (HOPE) prospective study
ConclusionIn this cohort of older adults with early-stage breast cancer, the combination of breast cancer and chemotherapy contributes to accelerated functional decline. Our findings reinforce the need to develop interventions aimed at preserving physical function, particularly during and after chemotherapy.Implications for Cancer SurvivorsThe high prevalence of accelerated functional decline in older women undergoing breast cancer chemotherapy underscores the urgency to develop interventions aimed at preserving physical function and improving health outcomes.Clinical TrialNCT01472094, Hurria Older PatiEnts (HOPE) with Bre...
Source: Journal of Cancer Survivorship - April 28, 2024 Category: Cancer & Oncology Source Type: research
Determining the relationship of p16INK4a and additional molecular markers of aging with clinical frailty in hematologic malignancy
ConclusionsOur pilot data suggest that multiple blood-based aging biomarkers have potential to identify frailty in older adults with HM.Implications for Cancer SurvivorsWe developed the I2 index to quantify impairments across geriatric domains and discovered that PBTL p16, Hannum, PhenoAge, and DunedinPACE are promising indicators of frailty in HM. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 28, 2024 Category: Cancer & Oncology Source Type: research
The prevalence of mild cognitive impairment in breast cancer patients receiving chemotherapy according to the criteria of the National Institute on Aging-Alzheimer ’s Association (NIA-AA)
ConclusionsTwenty percent of breast cancer patients treated with chemotherapy met NIA-AA criteria for MCI, compared with 7.6% of the controls.Implications for Cancer SurvivorsThese criteria, which include formal test performance as well as a person ’s symptoms and functional status, can be useful in clinical practice and scientific research. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 26, 2024 Category: Cancer & Oncology Source Type: research
Long-term quality of life of testicular cancer survivors differs according to applied adjuvant treatment and tumour type
ConclusionsThe applied adjuvant treatment and the tumour entity had a significant impact on the long-term QoL of TC survivors, even more than 25 years after the completion of therapy. Both RT and CT had a negative impact compared to survivors treated with RPLND, except for sexual concerns. NSGCT survivors had a lower impairment of QoL compared to seminoma survivors, except in terms of sexual concerns.Implications for Cancer SurvivorsImplications for cancer survivors are to raise awareness of aspects of long-term and late effects on QoL in TC survivors; offer supportive care, such as psycho-oncological support or lifestyl...
Source: Journal of Cancer Survivorship - April 24, 2024 Category: Cancer & Oncology Source Type: research
Cardiovascular screening outcomes in the Dutch survivorship care program for Hodgkin lymphoma survivors
ConclusionsAdherence to the screening guidelines in the Dutch HL survivorship care program was reasonable to good and a substantial number of actionable (risk factors for) CVD were diagnosed.Implications for Cancer Survivors.Our findings inform HL survivors at high risk of late cardiotoxicity about cardiovascular screening findings and demonstrate appropriate therapeutic actions after diagnosis of (risk factors for) CVD. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 23, 2024 Category: Cancer & Oncology Source Type: research
Changes in physical activity and diabetes risk after cancer diagnosis: a nationwide cohort study
ConclusionsRegular physical activity starting before a cancer diagnosis is associated with a lower risk of diabetes following the diagnosis, independent of established diabetes risk factors.Implications for Cancer SurvivorsThe study underscores the importance of engaging in sufficient physical activity to mitigate the risk of diabetes in cancer survivors.Graphical abstract (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 22, 2024 Category: Cancer & Oncology Source Type: research
Social characteristics and social benefit use among premenopausal breast cancer survivors in Denmark: a population-based cohort study
ConclusionsUse of social benefits reflecting lost ability to work was highest in less educated women and in women living alone.Implications for Cancer Survivors.Awareness of these groups is crucial when tailoring efforts to support work participation in cancer survivors. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 22, 2024 Category: Cancer & Oncology Source Type: research
The association of pre-cancer diagnosis cardiovascular risk factors with memory aging after a cancer diagnosis, overall and by race/ethnicity
ConclusionsCVRFs were associated with worse baseline memory function, but not decline, for cancer-free adults and cancer survivors. Racial disparities were largely similar between cancer survivors and cancer-free adults.Implications for Cancer SurvivorsThese findings may inform hypotheses about pre-diagnosis multimorbidity and cognitive aging of cancer survivors from diverse groups. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 22, 2024 Category: Cancer & Oncology Source Type: research
Can strength training or tai ji quan training reduce frailty in postmenopausal women treated with chemotherapy? A secondary data analysis of the GET FIT trial
ConclusionsStrength training appears superior to tai ji quan and stretching with respect to reducing overall frailty phenotype among postmenopausal women treated with chemotherapy for cancer, but tai ji quan favorably reduced the number of frailty criteria.Trial registrationClinicalTrials.gov identifier: GET FIT was registered as a clinical trial in clinicaltrials.gov: NCT01635413.Implications for Cancer SurvivorsSupervised, group exercise training that emphasizes strength training and/or tai ji quan may help combat accelerated aging and reduce frailty after cancer treatment. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 20, 2024 Category: Cancer & Oncology Source Type: research
A pilot randomized controlled trial of an online intervention for Hodgkin lymphoma survivors to increase knowledge about late effects and recommended screening
ConclusionOnline education modules for high-risk HL survivors are an acceptable method to improve knowledge of health risks and screening guidelines. Future interventions should focus on improving screening uptake in this population.Implications for Cancer SurvivorsWeb-based learning can be useful in increasing cancer survivor knowledge of their unique risks and screening recommendations but does not necessarily change patient behavior. Involvement in a cancer survivorship program can help assess individual barriers and monitor uptake of screening. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 20, 2024 Category: Cancer & Oncology Source Type: research
Associations between mitochondrial copy number, exercise capacity, physiologic cost of walking, and cardiac strain in young adult survivors of childhood cancer
ConclusionsIncreased mtDNA-CN is associated with decreased odds of abnormal cardiac function in childhood cancer survivors.Implications for Cancer SurvivorsThese findings demonstrate a potential role for mtDNA-CN as a biomarker of early cardiac dysfunction in this population. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 18, 2024 Category: Cancer & Oncology Source Type: research
Spiritual well-being, faith, meaning in life, peace, and purpose in life for cancer-related fatigue: systematic review with meta-analysis and meta-regressions
ConclusionsCancer-related fatigue may be correlated with spiritual well-being. However, the certainty of evidence was very low across the meta-analyzed outcomes.Implications for Cancer SurvivorsA negative correlation was observed between spiritual well-being and cancer-related fatigue. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 18, 2024 Category: Cancer & Oncology Source Type: research
Attitudes of people diagnosed with cancer and cancer care providers towards use of nicotine vaping products in high-income countries: a scoping review
ConclusionFindings show differences in beliefs and attitudes of e-cigarettes between clinicians and people diagnosed with cancer. Additional research into the health impacts of e-cigarettes in people with a current or previous cancer diagnosis will allow for greater congruence between patients and clinicians and assist providers in recommending effective tools for smoking cessation within this population.Implications for Cancer SurvivorsThis study provides an overview of the attitudes, beliefs and perceptions of e-cigarette use among people with a current or previous diagnosis of cancer and health practitioners. Given the ...
Source: Journal of Cancer Survivorship - April 17, 2024 Category: Cancer & Oncology Source Type: research
Trends in ototoxicity monitoring among cisplatin-treated patients with cancer
ConclusionsOtotoxicity monitoring is an inconsistent practice, particularly during chemotherapy and for long-term surveillance of hearing loss. Patients with non –head and neck cancer may be at increased risk for loss of audiologic follow-up.Implications for Cancer SurvivorsCisplatin ototoxicity is a common occurrence that can be effectively managed with auditory rehabilitation. Therefore, referrals to audiology and counseling on treatment-related ototoxicity are recommended throughout chemotherapy and cancer survivorship. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - April 17, 2024 Category: Cancer & Oncology Source Type: research
