PD-BAT: A novel approach of pooling basophil donors for expansion of commercial laboratory testing of Chronic Spontaneous Urticaria
In this study, we introduce an innovative approach where multiple potential basophil donors undergo rigorous BAT characterization alongside control samples. By selecting and pooling donors with optimal performance, we significantly enhance the inter-assay reproducibility of the indirect BAT test.PMID:38679364 | DOI:10.1016/j.jim.2024.113679 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 28, 2024 Category: Allergy & Immunology Authors: Saintedym Wills Jessica Chavez Ajay Grover Nathanael Beck Michele Romano Christina Bauer Michael Gerspach Michael Schneider Andre Valcour Source Type: research
PD-BAT: A novel approach of pooling basophil donors for expansion of commercial laboratory testing of Chronic Spontaneous Urticaria
In this study, we introduce an innovative approach where multiple potential basophil donors undergo rigorous BAT characterization alongside control samples. By selecting and pooling donors with optimal performance, we significantly enhance the inter-assay reproducibility of the indirect BAT test.PMID:38679364 | DOI:10.1016/j.jim.2024.113679 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 28, 2024 Category: Allergy & Immunology Authors: Saintedym Wills Jessica Chavez Ajay Grover Nathanael Beck Michele Romano Christina Bauer Michael Gerspach Michael Schneider Andre Valcour Source Type: research
PD-BAT: A novel approach of pooling basophil donors for expansion of commercial laboratory testing of Chronic Spontaneous Urticaria
In this study, we introduce an innovative approach where multiple potential basophil donors undergo rigorous BAT characterization alongside control samples. By selecting and pooling donors with optimal performance, we significantly enhance the inter-assay reproducibility of the indirect BAT test.PMID:38679364 | DOI:10.1016/j.jim.2024.113679 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 28, 2024 Category: Allergy & Immunology Authors: Saintedym Wills Jessica Chavez Ajay Grover Nathanael Beck Michele Romano Christina Bauer Michael Gerspach Michael Schneider Andre Valcour Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Development of a defibrinated human blood hemolysis assay for rapid testing of hemolytic activity compared to computational prediction
CONCLUSION: We introduce a standardized, more accurate protocol for assessing hemolytic activity using defibrinated human red blood cells. This approach, facilitated by the increased commercial availability of de-identified human blood and defibrination methods, offers a robust tool for evaluating toxicity of emerging drug compounds, especially AMPs.PMID:38604530 | DOI:10.1016/j.jim.2024.113670 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 11, 2024 Category: Allergy & Immunology Authors: Ashley M Carpenter Monique L van Hoek Source Type: research
Humoral and cellular response of two different vaccines against SARS-CoV-2 in a group of healthcare workers: Comment
J Immunol Methods. 2024 Apr 7;529:113671. doi: 10.1016/j.jim.2024.113671. Online ahead of print.NO ABSTRACTPMID:38593868 | DOI:10.1016/j.jim.2024.113671 (Source: Journal of Immunological Methods)
Source: Journal of Immunological Methods - April 9, 2024 Category: Allergy & Immunology Authors: Hinpetch Daungsupawong Viroj Wiwanitkit Source Type: research
