Vegan grade medium component screening and concentration optimization for the fermentation of the probiotic strain Lactobacillus paracasei IMC 502 ® using Design of Experiments
J Ind Microbiol Biotechnol. 2024 Apr 24:kuae016. doi: 10.1093/jimb/kuae016. Online ahead of print.ABSTRACTLactobacillus paracasei IMC502® is a commercially successful probiotic strain, however, there are no reports that investigate growth medium composition in relation to improved biomass production for this strain. The major outcome of the present study is the design and optimization of a growth medium based on vegan components to be used in the cultivation of Lactobacillus paracasei IMC502®, by using Design of Experiments (DoE). Besides comparing different carbon sources, the use of plant-based peptones as nitrogen sou...
Source: Journal of Industrial Microbiology and Biotechnology - April 24, 2024 Category: Microbiology Authors: Darshankumar Parecha Alberto Alfano Donatella Cimini Chiara Schiraldi Source Type: research

Vegan grade medium component screening and concentration optimization for the fermentation of the probiotic strain Lactobacillus paracasei IMC 502 ® using Design of Experiments
J Ind Microbiol Biotechnol. 2024 Apr 24:kuae016. doi: 10.1093/jimb/kuae016. Online ahead of print.ABSTRACTLactobacillus paracasei IMC502® is a commercially successful probiotic strain, however, there are no reports that investigate growth medium composition in relation to improved biomass production for this strain. The major outcome of the present study is the design and optimization of a growth medium based on vegan components to be used in the cultivation of Lactobacillus paracasei IMC502®, by using Design of Experiments (DoE). Besides comparing different carbon sources, the use of plant-based peptones as nitrogen sou...
Source: Journal of Industrial Microbiology and Biotechnology - April 24, 2024 Category: Microbiology Authors: Darshankumar Parecha Alberto Alfano Donatella Cimini Chiara Schiraldi Source Type: research

Vegan grade medium component screening and concentration optimization for the fermentation of the probiotic strain Lactobacillus paracasei IMC 502 ® using Design of Experiments
J Ind Microbiol Biotechnol. 2024 Apr 24:kuae016. doi: 10.1093/jimb/kuae016. Online ahead of print.ABSTRACTLactobacillus paracasei IMC502® is a commercially successful probiotic strain, however, there are no reports that investigate growth medium composition in relation to improved biomass production for this strain. The major outcome of the present study is the design and optimization of a growth medium based on vegan components to be used in the cultivation of Lactobacillus paracasei IMC502®, by using Design of Experiments (DoE). Besides comparing different carbon sources, the use of plant-based peptones as nitrogen sou...
Source: Journal of Industrial Microbiology and Biotechnology - April 24, 2024 Category: Microbiology Authors: Darshankumar Parecha Alberto Alfano Donatella Cimini Chiara Schiraldi Source Type: research

Vegan grade medium component screening and concentration optimization for the fermentation of the probiotic strain Lactobacillus paracasei IMC 502 ® using Design of Experiments
J Ind Microbiol Biotechnol. 2024 Apr 24:kuae016. doi: 10.1093/jimb/kuae016. Online ahead of print.ABSTRACTLactobacillus paracasei IMC502® is a commercially successful probiotic strain, however, there are no reports that investigate growth medium composition in relation to improved biomass production for this strain. The major outcome of the present study is the design and optimization of a growth medium based on vegan components to be used in the cultivation of Lactobacillus paracasei IMC502®, by using Design of Experiments (DoE). Besides comparing different carbon sources, the use of plant-based peptones as nitrogen sou...
Source: Journal of Industrial Microbiology and Biotechnology - April 24, 2024 Category: Microbiology Authors: Darshankumar Parecha Alberto Alfano Donatella Cimini Chiara Schiraldi Source Type: research

Vegan grade medium component screening and concentration optimization for the fermentation of the probiotic strain Lactobacillus paracasei IMC 502 ® using Design of Experiments
J Ind Microbiol Biotechnol. 2024 Apr 24:kuae016. doi: 10.1093/jimb/kuae016. Online ahead of print.ABSTRACTLactobacillus paracasei IMC502® is a commercially successful probiotic strain, however, there are no reports that investigate growth medium composition in relation to improved biomass production for this strain. The major outcome of the present study is the design and optimization of a growth medium based on vegan components to be used in the cultivation of Lactobacillus paracasei IMC502®, by using Design of Experiments (DoE). Besides comparing different carbon sources, the use of plant-based peptones as nitrogen sou...
Source: Journal of Industrial Microbiology and Biotechnology - April 24, 2024 Category: Microbiology Authors: Darshankumar Parecha Alberto Alfano Donatella Cimini Chiara Schiraldi Source Type: research

Vegan grade medium component screening and concentration optimization for the fermentation of the probiotic strain Lactobacillus paracasei IMC 502 ® using Design of Experiments
J Ind Microbiol Biotechnol. 2024 Apr 24:kuae016. doi: 10.1093/jimb/kuae016. Online ahead of print.ABSTRACTLactobacillus paracasei IMC502® is a commercially successful probiotic strain, however, there are no reports that investigate growth medium composition in relation to improved biomass production for this strain. The major outcome of the present study is the design and optimization of a growth medium based on vegan components to be used in the cultivation of Lactobacillus paracasei IMC502®, by using Design of Experiments (DoE). Besides comparing different carbon sources, the use of plant-based peptones as nitrogen sou...
Source: Journal of Industrial Microbiology and Biotechnology - April 24, 2024 Category: Microbiology Authors: Darshankumar Parecha Alberto Alfano Donatella Cimini Chiara Schiraldi Source Type: research

Unlocking Growth Potential in Halomonas bluephagenesis for Enhanced PHA Production with Sulfate Ions
In conclusion, stimulating H. bluephagenesis (TDH4A1B5P) to produce PHA is a feasible and suitable strategy for all H. bluephagenesis.PMID:38632039 | DOI:10.1093/jimb/kuae013 (Source: Journal of Industrial Microbiology and Biotechnology)
Source: Journal of Industrial Microbiology and Biotechnology - April 17, 2024 Category: Microbiology Authors: Fuwei Yao Kai Yuan Weiqiang Zhou Weitao Tang Tang Tang Xiaofan Yang Haijun Liu Fangliang Li Qing Xu Chao Peng Source Type: research

Discovery of Streptomyces species CS-62, a novel producer of the Acinetobacter baumannii selective antibiotic factumycin
J Ind Microbiol Biotechnol. 2024 Apr 17:kuae014. doi: 10.1093/jimb/kuae014. Online ahead of print.ABSTRACTNarrow spectrum antibiotics are of great interest given their ability to spare the microbiome and decrease widespread antibiotic resistance compared to broad spectrum antibiotics. Herein we screened an in-house library of Actinobacteria strains for selective activity against Acinetobacter baumannii and successfully identified Streptomyces sp. CS-62 as a producer of a natural product with this valuable activity. Analysis of the cultures via high resolution mass spectrometry and tandem mass spectrometry followed by compa...
Source: Journal of Industrial Microbiology and Biotechnology - April 17, 2024 Category: Microbiology Authors: Amir Y Alwali Diane Santos C ésar Aguilar Audrey Birch Lorena Rodriguez-Ordu ña Carson B Roberts Ramya Modi Cuauhtemoc Licona-Cassani Elizabeth I Parkinson Source Type: research

Unlocking Growth Potential in Halomonas bluephagenesis for Enhanced PHA Production with Sulfate Ions
In conclusion, stimulating H. bluephagenesis (TDH4A1B5P) to produce PHA is a feasible and suitable strategy for all H. bluephagenesis.PMID:38632039 | DOI:10.1093/jimb/kuae013 (Source: Journal of Industrial Microbiology and Biotechnology)
Source: Journal of Industrial Microbiology and Biotechnology - April 17, 2024 Category: Microbiology Authors: Fuwei Yao Kai Yuan Weiqiang Zhou Weitao Tang Tang Tang Xiaofan Yang Haijun Liu Fangliang Li Qing Xu Chao Peng Source Type: research

Discovery of Streptomyces species CS-62, a novel producer of the Acinetobacter baumannii selective antibiotic factumycin
J Ind Microbiol Biotechnol. 2024 Apr 17:kuae014. doi: 10.1093/jimb/kuae014. Online ahead of print.ABSTRACTNarrow spectrum antibiotics are of great interest given their ability to spare the microbiome and decrease widespread antibiotic resistance compared to broad spectrum antibiotics. Herein we screened an in-house library of Actinobacteria strains for selective activity against Acinetobacter baumannii and successfully identified Streptomyces sp. CS-62 as a producer of a natural product with this valuable activity. Analysis of the cultures via high resolution mass spectrometry and tandem mass spectrometry followed by compa...
Source: Journal of Industrial Microbiology and Biotechnology - April 17, 2024 Category: Microbiology Authors: Amir Y Alwali Diane Santos C ésar Aguilar Audrey Birch Lorena Rodriguez-Ordu ña Carson B Roberts Ramya Modi Cuauhtemoc Licona-Cassani Elizabeth I Parkinson Source Type: research

Unlocking Growth Potential in Halomonas bluephagenesis for Enhanced PHA Production with Sulfate Ions
In conclusion, stimulating H. bluephagenesis (TDH4A1B5P) to produce PHA is a feasible and suitable strategy for all H. bluephagenesis.PMID:38632039 | DOI:10.1093/jimb/kuae013 (Source: Journal of Industrial Microbiology and Biotechnology)
Source: Journal of Industrial Microbiology and Biotechnology - April 17, 2024 Category: Microbiology Authors: Fuwei Yao Kai Yuan Weiqiang Zhou Weitao Tang Tang Tang Xiaofan Yang Haijun Liu Fangliang Li Qing Xu Chao Peng Source Type: research

Discovery of Streptomyces species CS-62, a novel producer of the Acinetobacter baumannii selective antibiotic factumycin
J Ind Microbiol Biotechnol. 2024 Apr 17:kuae014. doi: 10.1093/jimb/kuae014. Online ahead of print.ABSTRACTNarrow spectrum antibiotics are of great interest given their ability to spare the microbiome and decrease widespread antibiotic resistance compared to broad spectrum antibiotics. Herein we screened an in-house library of Actinobacteria strains for selective activity against Acinetobacter baumannii and successfully identified Streptomyces sp. CS-62 as a producer of a natural product with this valuable activity. Analysis of the cultures via high resolution mass spectrometry and tandem mass spectrometry followed by compa...
Source: Journal of Industrial Microbiology and Biotechnology - April 17, 2024 Category: Microbiology Authors: Amir Y Alwali Diane Santos C ésar Aguilar Audrey Birch Lorena Rodriguez-Ordu ña Carson B Roberts Ramya Modi Cuauhtemoc Licona-Cassani Elizabeth I Parkinson Source Type: research

Multi-modular metabolic engineering and efflux engineering for enhanced lycopene production in recombinant Saccharomyces cerevisiae
J Ind Microbiol Biotechnol. 2024 Apr 15:kuae015. doi: 10.1093/jimb/kuae015. Online ahead of print.ABSTRACTLycopene has been widely used in the food industry and medical field due to its antioxidant, anti-cancer, and anti-inflammatory properties. However, achieving efficient manufacture of lycopene using chassis cells on an industrial scale remains a major challenge. Herein, we attempted to integrate multiple metabolic engineering strategies to establish an efficient and balanced lycopene biosynthetic system in Saccharomyces cerevisiae. First, the lycopene synthesis pathway was modularized to sequentially enhance the metabo...
Source: Journal of Industrial Microbiology and Biotechnology - April 15, 2024 Category: Microbiology Authors: Guangxi Huang Jiarong Li Jingyuan Lin Changqing Duan Guoliang Yan Source Type: research

Multi-modular metabolic engineering and efflux engineering for enhanced lycopene production in recombinant Saccharomyces cerevisiae
J Ind Microbiol Biotechnol. 2024 Apr 15:kuae015. doi: 10.1093/jimb/kuae015. Online ahead of print.ABSTRACTLycopene has been widely used in the food industry and medical field due to its antioxidant, anti-cancer, and anti-inflammatory properties. However, achieving efficient manufacture of lycopene using chassis cells on an industrial scale remains a major challenge. Herein, we attempted to integrate multiple metabolic engineering strategies to establish an efficient and balanced lycopene biosynthetic system in Saccharomyces cerevisiae. First, the lycopene synthesis pathway was modularized to sequentially enhance the metabo...
Source: Journal of Industrial Microbiology and Biotechnology - April 15, 2024 Category: Microbiology Authors: Guangxi Huang Jiarong Li Jingyuan Lin Changqing Duan Guoliang Yan Source Type: research

Multi-modular metabolic engineering and efflux engineering for enhanced lycopene production in recombinant Saccharomyces cerevisiae
J Ind Microbiol Biotechnol. 2024 Apr 15:kuae015. doi: 10.1093/jimb/kuae015. Online ahead of print.ABSTRACTLycopene has been widely used in the food industry and medical field due to its antioxidant, anti-cancer, and anti-inflammatory properties. However, achieving efficient manufacture of lycopene using chassis cells on an industrial scale remains a major challenge. Herein, we attempted to integrate multiple metabolic engineering strategies to establish an efficient and balanced lycopene biosynthetic system in Saccharomyces cerevisiae. First, the lycopene synthesis pathway was modularized to sequentially enhance the metabo...
Source: Journal of Industrial Microbiology and Biotechnology - April 15, 2024 Category: Microbiology Authors: Guangxi Huang Jiarong Li Jingyuan Lin Changqing Duan Guoliang Yan Source Type: research