A mitochondrion-targeted cyanine agent for NIR-II fluorescence-guided surgery combined with intraoperative photothermal therapy to reduce prostate cancer recurrence
Poorly identified tumor boundaries and nontargeted therapies lead to the high recurrence rates and poor quality of life of prostate cancer patients. Near-infrared-II (NIR-II) fluorescence imaging provides cert... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 3, 2024 Category: Nanotechnology Authors: Chenchen Liu, Zong Chang, Kailei Chen, Qiang Xue, Bingxin Shu, Zhihao Wei, Xuan Zhou, Like Guo, Yuling Zhang, Yingying Pan, Qi Cao, Huageng Liang, Qinchao Sun and Xiaoping Zhang Tags: Research Source Type: research
Migrasomes from adipose derived stem cells enrich CXCL12 to recruit stem cells via CXCR4/RhoA for a positive feedback loop mediating soft tissue regeneration
Adipose-derived stem cells (ASCs) represent the most advantageous choice for soft tissue regeneration. Studies proved the recruitment of ASCs post tissue injury was mediated by chemokine CXCL12, but the mechan... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 3, 2024 Category: Nanotechnology Authors: Yunzi Chen, Ye Li, Bin Li, Delin Hu, Ziqing Dong and Feng Lu Tags: Research Source Type: research
The effects of exosomes originating from different cell sources on the differentiation of bone marrow mesenchymal stem cells into schwann cells
Bone marrow mesenchymal stem cells (BMSCs) can differentiate into Schwann cells (SCs) during peripheral nerve injury; in our previous research, we showed that SC-derived exosomes (SC-exos) played a direct indu... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 3, 2024 Category: Nanotechnology Authors: Hui Wang, Xianxiang Zhang, Weiwei Zhang and Hao Sun Tags: Research Source Type: research
Single-sEV profiling identifies the TACSTD2 + sEV subpopulation as a factor of tumor susceptibility in the elderly
Aging is a very complex physiological phenomenon, and sEVs are involved in the regulation of this mechanism. Serum samples from healthy individuals under 30 and over 60 years of age were collected to analyze d... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 3, 2024 Category: Nanotechnology Authors: Nannan Ning, Jianying Lu, Qianpeng Li, Mengmeng Li, Yanling Cai, Hongchun Wang and Jingxin Li Tags: Research Source Type: research
Engineered nanoparticles promote cardiac tropism of AAV vectors
Cardiac muscle targeting is a notoriously difficult task. Although various nanoparticle (NP) and adeno-associated viral (AAV) strategies with heart tissue tropism have been developed, their performance remains... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 3, 2024 Category: Nanotechnology Authors: Lauren Switala, Lin Di, Huiyun Gao, Courteney Asase, Matthew Klos, Palanivel Rengasamy, Daria Fedyukina and Andrei Maiseyeu Tags: Research Source Type: research
A lava-inspired proteolytic enzyme therapy on cancer with a PEG-based hydrogel enhances tumor distribution and penetration of liposomes
The enhanced permeability and retention (EPR) effect has become the guiding principle for nanomedicine against cancer for a long time. However, several biological barriers severely resist therapeutic agents ’ p... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 2, 2024 Category: Nanotechnology Authors: Jiaojiao Li, Dandan Mi, Rujing Wang, Yuke Li, Mengnan Zhao and Sanjun Shi Tags: Research Source Type: research
Advances in the application of extracellular vesicles derived from three-dimensional culture of stem cells
Stem cells (SCs) have been used therapeutically for decades, yet their applications are limited by factors such as the risk of immune rejection and potential tumorigenicity. Extracellular vesicles (EVs), a key... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - May 1, 2024 Category: Nanotechnology Authors: Wenya Chen, Peipei Wu, Can Jin, Yinjie Chen, Chong Li and Hui Qian Tags: Review Source Type: research
Ångstrom-scale gold particles loaded with alendronate via alpha-lipoic acid alleviate bone loss in osteoporotic mice
Osteoporosis is a highly prevalent metabolic disease characterized by low systemic bone mass and deterioration of bone microarchitecture, resulting in reduced bone strength and increased fracture risk. Current... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 30, 2024 Category: Nanotechnology Authors: Weihang Gao, Jiao Jiao Li, Jingyu Shi, Hongbing Lan, Yuanyuan Guo and Dehao Fu Tags: Research Source Type: research
Photodynamic and nitric oxide therapy-based synergistic antimicrobial nanoplatform: an advanced root canal irrigation system for endodontic bacterial infections
The main issues faced during the treatment of apical periodontitis are the management of bacterial infection and the facilitation of the repair of alveolar bone defects to shorten disease duration. Conventiona... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 30, 2024 Category: Nanotechnology Authors: Youyun Zeng, Xiangyu Hu, Zhibin Cai, Dongchao Qiu, Ying Ran, Yiqin Ding, Jiayi Shi, Xiaojun Cai and Yihuai Pan Tags: Research Source Type: research
Biomimetic nanodrug blocks CD73 to inhibit adenosine and boosts antitumor immune response synergically with photothermal stimulation
Combination of tumor immunotherapy with photothermal therapy (PTT) is a feasible tactic to overcome the drawback of immunotherapy such as poor immune response. Via triggering the immunogenic cells death (ICD), PT... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 30, 2024 Category: Nanotechnology Authors: Tan Li, Xingyu Zhang, Chengyu Shi, Qiao Liu and Yuetao Zhao Tags: Research Source Type: research
Electrospun nanofibers synthesized from polymers incorporated with bioactive compounds for wound healing
The development of innovative wound dressing materials is crucial for effective wound care. It ’s an active area of research driven by a better understanding of chronic wound pathogenesis. Addressing wound care... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 27, 2024 Category: Nanotechnology Authors: Naveen Palani, Pradeshwaran Vijayakumar, P. Monisha, Saravanakumar Ayyadurai and Suriyaprakash Rajadesingu Tags: Review Source Type: research
Carbon dots as a novel photosensitizer for photodynamic therapy of cancer and bacterial infectious diseases: recent advances
Carbon dots (CDs) are novel carbon-based nanomaterials that have been used as photosensitizer-mediated photodynamic therapy (PDT) in recent years due to their good photosensitizing activity. Photosensitizers (... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 26, 2024 Category: Nanotechnology Authors: Lingxiang Sun, Yifan Zhao, Hongyi Peng, Jian Zhou, Qingmei Zhang, Jingyu Yan, Yingyu Liu, Susu Guo, Xiuping Wu and Bing Li Tags: Review Source Type: research
Young osteocyte-derived extracellular vesicles facilitate osteogenesis by transferring tropomyosin-1
Bone marrow mesenchymal stem cells (BMSCs) can undergo inadequate osteogenesis or excessive adipogenesis as they age due to changes in the bone microenvironment, ultimately resulting in decreased bone density ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 25, 2024 Category: Nanotechnology Authors: Zhen-Xing Wang, Xiao Lin, Jia Cao, Yi-Wei Liu, Zhong-Wei Luo, Shan-Shan Rao, Qiang Wang, Yi-Yi Wang, Chun-Yuan Chen, Guo-Qiang Zhu, Fu-Xing-Zi Li, Yi-Juan Tan, Yin Hu, Hao Yin, You-You Li, Ze-Hui He & hellip; Tags: Research Source Type: research
LIFU/MMP-2 dual-responsive release of repurposed drug disulfiram from nanodroplets for inhibiting vasculogenic mimicry and lung metastasis in triple-negative breast cancer
Vasculogenic mimicry (VM), when microvascular channels are formed by cancer cells independent of endothelial cells, often occurs in deep hypoxic areas of tumors and contributes to the aggressiveness and metast... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 25, 2024 Category: Nanotechnology Authors: Ying Liu, Rui Tang, Yuting Cao, Nianhong Wu, Qiaoxi Qin, Yuanyuan Chen, Xi Wei, Jianli Ren, Yang Sun, Hong Zhou, Yang Zhou and Pan Li Tags: Research Source Type: research
The potential use of nanozymes as an antibacterial agents in oral infection, periodontitis, and peri-implantitis
Several studies suggest that oral pathogenic biofilms cause persistent oral infections. Among these is periodontitis, a prevalent condition brought on by plaque biofilm. It can even result in tooth loss. Furth... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 25, 2024 Category: Nanotechnology Authors: Mohammad Hosseini Hooshiar, Ashkan Badkoobeh, Shirin Kolahdouz, Azadeh Tadayonfard, Asieh Mozaffari, Kamyar Nasiri, Sara Salari, Reza Safaralizadeh and Saman Yasamineh Tags: Review Source Type: research
