Journal of Stroke and Cerebrovascular Diseases This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Edaravone dexborneol regulates γ-aminobutyric acid transaminase in rats with acute intracerebral hemorrhage
Edaravone dexborneol is neuroprotective against ischemic stroke, with free radical-scavenging and anti-inflammatory effects, but its effects in hemorrhagic stroke remain unclear. We evaluated whether edaravone dexborneol has a neuroprotective effect in intracerebral hemorrhage, and its underlying mechanisms. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 1, 2024 Category: Neurology Authors: Rui Yang, Jia Li, Li Zhao, Ming Zhang, Yaya Qin, Xiaoqiong Tong, Shenglin Wang, Fanhui Yang, Guohui Jiang Source Type: research

Mendelian randomization analyses reveal causal relationship between liver volume and stroke
This study aims to utilize Mendelian randomization (MR) to explore the genetic causal relationship between them. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 1, 2024 Category: Neurology Authors: Changyun Zhang, YuQiu Li, Chuanzhu Yan, Huijuan Yu, Xin Zhang Source Type: research

Hypothyroidism's Effect on Stroke Limited to Specific Subtypes: A Mendelian Randomization Study
This study aimed to explore the causal effect of hypothyroidism on the risk of stroke and its subtypes by Mendelian randomization (MR) analysis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 28, 2024 Category: Neurology Authors: Xinmin Deng, Wen Chang, Jingyi Zhu, Xiaofeng Lv, Rui Lai, Yu Cai, Shanshan Liu, Jingtao Liang Source Type: research

A novel p55PIK signaling peptide inhibitor alleviates neuroinflammation via the STAT3/NF-kB signaling pathway in experimental stroke
Ischemic stroke remains the predominant contributor to mortality and disability globally. Microglia undergo rapid activation and initiate inflammatory cascade reactions by phenotypic polarization, participating in the regulation of inflammatory injury and tissue repair post-ischemic stroke. Regulating microglia-mediated neuroinflammation is a promising therapeutic strategy for ischemic stroke. Previously, we designed and synthesized a novel p55PIK inhibitor, TAT-N15 polypeptide, which presents inhibitive activity on NF- κB signaling-mediated inflammation in acute conjunctivitis and allergic rhinitis. (Source: Journal of S...
Source: Journal of Stroke and Cerebrovascular Diseases - April 26, 2024 Category: Neurology Authors: Yujing Liu, Changlong Leng, Youwei Li, Meiling Zhou, Xiansheng Ye, Chaoxing Li, Xianmin Xia, Binlian Sun, Xiji Shu, Wei Liu Source Type: research

The Effect of Sodium-Glucose Transporter 2 Inhibitors on Stroke in Patients With Type 2 Diabetes: A Meta-analysis
To provide an update on the effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors on stroke in patients with type 2 diabetes (T2D). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 26, 2024 Category: Neurology Authors: Eric Pasqualotto, Farley Reis Rodrigues, Giovana Barros e Silva Ribeiro, Gustavo de Oliveira Almeida, J úlia Camargo Kabariti, Rafael Oliva Morgado Ferreira, Matheus Pedrotti Chavez, Mariana R.C. Clemente, Nicole B. Sur, Daniel G. Di Luca Source Type: research

Importance of Sex and Gender Differences in Enrollment and Interpretation of Stroke Clinical Trials
This review aims to reinforce the importance of improving sex balance in preclinical trials and sex and gender diversity and proportional balance in clinical trials enrollment and how this influences interpretation of stroke clinical trials. It also aims to identify strategies for improvement in data collection. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 25, 2024 Category: Neurology Authors: Tina M. Burton, Tracy E. Madsen, Rebecca Karb, Karen L. Furie Source Type: research

Association between the quantity of stroke care units and the complement of neurosurgical and neurology specialists in Japan: A retrospective study
Initial treatment in a stroke unit (SU) can reduce the mortality of stroke victims, increase the rate of discharge to home, and decrease the amount of time spent in the hospital. The effectiveness of an SU has also been proven in a meta-analysis. Stroke units have been established in various locations in Europe since 1990, and the medical system for managing the acute phase of stroke has improved1, 2. The Japanese Stroke Association recommends in its Stroke Treatment Guidelines 2021 that acute stroke patients should be treated by a multidisciplinary stroke team in an SU that provides intensive care and early rehabilitation...
Source: Journal of Stroke and Cerebrovascular Diseases - April 24, 2024 Category: Neurology Authors: Kentaro Hara, Masato Kanda, Hiroyo Kuwabara, Yoshio Kobayashi, Takahiro Inoue Source Type: research

A Systematic Review of the Epidemiology and The Public Health Implications of Stroke in Sub-Saharan Africa
With approximately 11 million strokes occurring annually worldwide, and over 6.5 million deaths annually, stroke has made its place as one of the major killers in the world. Although developing countries make up more than 4/5 of the global stroke burden, well-grounded information on stroke epidemiology remains lacking there. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 23, 2024 Category: Neurology Authors: Gisele Abissegue, Seidina Iliasu Yakubu, Aiswarya Seema Ajay, Faatihah Niyi-Odumosu Source Type: research

Application of Interpretable Machine Learning Algorithms to Predict Acute Kidney Injury in Patients with Cerebral Infarction in ICU
This study aimed to explore the application of interpretable machine learning algorithms in predicting AKI in patients with cerebral infarction. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 22, 2024 Category: Neurology Authors: Xiaochi Lu, Yi Chen, Gongping Zhang, Xu Zeng, Linjie Lai, Chaojun Qu Source Type: research

Quantitative Imaging for Predicting Hematoma Expansion in Intracerebral Hemorrhage: A Multimodel Comparison
Several studies report that radiomics provides additional information for predicting hematoma expansion in intracerebral hemorrhage (ICH). However, the comparison of diagnostic performance of radiomics for predicting revised hematoma expansion (RHE) remains unclear. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 22, 2024 Category: Neurology Authors: Wen-Song Yang, Jia-Yang Liu, Yi-Qing Shen, Xiong-Fei Xie, Shu-Qiang Zhang, Fang-Yu Liu, Jia-Lun Yu, Yong-Bo Ma, Zhong-Song Xiao, Hao-Wei Duan, Qi Li, Shan-Xiong Chen, Peng Xie Source Type: research

Prevalence of symptoms of post stroke depression and anxiety in young adults: a systematic review and meta-analysis
Young adults with stroke have distinct professional and social roles making them vulnerable to symptoms of post-stroke depression (PSD) and post-stroke anxiety (PSA). Prior reviews have examined the prevalence of anxiety and depression in stroke populations. However, there are a lack of studies that have focused on these conditions in young adults. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 22, 2024 Category: Neurology Authors: Katrina Hannah D. Ignacio, Ryan T. Muir, Jose Danilo B. Diestro, Nishita Singh, Melody Hope Lim Lee Yu, Omar El Omari, Rana Abdalrahman, Suzanne L. Barker-Collo, Maree L. Hackett, Sean P. Dukelow, Mohammed A. Almekhlafi Source Type: research

Protein kinase C-inhibition reduces critical weight loss and improves functional outcome after experimental subarachnoid haemorrhage
This study was undertaken to analyse functional outcomes up to 14 days after experimental SAH. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 18, 2024 Category: Neurology Authors: Jesper P B ömers, Anja Holm, Spyridoula Kazantzi, Professor Lars Edvinsson, Professor Tiit I Mathiesen, Kristian A Haanes Source Type: research

De Novo Brain Vascular Malformation in an Adult with Hereditary Hemorrhagic Telangiectasia and Juvenile Polyposis Overlap Syndrome
The development of brain vascular malformation (BVM) is rare in adults. The Hereditary Hemorrhagic Telangiectasia (HHT) Clinical Guidelines recommend BVM screening with magnetic resonance imaging (MRI) at the time of diagnosis. However, these guidelines apply broadly to the HHT population and do not account for patients with Mothers Against Decapentaplegic Homolog 4 (MADH4) mutations, often presenting other hypermobility features and cardiovascular anomalies (e.g., Aortic root aneurysms, vascular kinking). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 17, 2024 Category: Neurology Authors: Elisa Guan, Carolina Vazquez, Ana Braslavsky, Cristina H. Besada, Akly Manuel S. Perez, Oscar Peralta, Monaco Ricardo Garc ía, Matteo Baccanelli, Nicolás M. Ciarrocchi, Marcelo M. Serra Tags: Case Report Source Type: research

The Predictive Value of Serum F-actin on the Severity and Early Neurological Deterioration of Acute Ischemic Stroke
F-actin is involved in the progression of ischemic stroke and is associated with the disruption of the blood-brain barrier. In this article, we evaluated serum F-actin as a biomarker in stroke severity and early neurological deterioration (END) in acute ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 17, 2024 Category: Neurology Authors: Jiaqian Li, Binda Wang, Fangyu Dai, Xuelian Kou, Guangyong Wu, Bin Wu, Jie Xu, Lulan Pan, Jingjing Liu, Songbin He, Feng Gao Source Type: research

Health Care-Associated Infections after Surgical Treatment of Ruptured Intracranial Aneurysms
Aneurysmal subarachnoid hemorrhage (SAH) is catastrophic, and microsurgery for ruptured intracranial aneurysms is one of the preventive modalities for rebleeding. However, patients remain at high risk of medical morbidities after surgery, one of the most important of which is health care-associated infections (HAIs). We analyzed the incidence and risk factors of HAIs, as well as their association with the outcomes after surgical treatment of ruptured aneurysms. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2024 Category: Neurology Authors: Yu-Hua Huang, Tsung-Han Lee Source Type: research