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Population impacts of conditional financial incentives and a male-targeted digital decision support application on the HIV treatment cascade in rural KwaZulu Natal: findings from the HITS cluster randomized clinical trial
CONCLUSIONS: Small CFIs can contribute to achieve the first step of the HIV care cascade. However, neither CFIs nor EPIC-HIV was sufficient to increase the number of people on ART. Additional evidence is needed to confirm the impact of EPIC-HIV on viral suppression.PMID:38695099 | DOI:10.1002/jia2.26248 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 2, 2024 Category: Infectious Diseases Authors: Maxime Inghels Hae-Young Kim Thulile Mathenjwa Maryam Shahmanesh Janet Seeley Sally Wyke Philippa Matthews Oluwafemi Adeagbo Dickman Gareta Nuala McGrath H Manisha Yapa Ann Blandford Thembelihle Zuma Adrian Dobra Till B ärnighausen Frank Tanser Source Type: research

Impact of simplified HCV diagnostic strategies on the HCV epidemic among men who have sex with men in the era of HIV oral pre-exposure prophylaxis in Taiwan: a modelling study
CONCLUSIONS: Simplified HCV diagnostic strategies could control the ongoing HCV epidemic and improve HCV testing and treatment among Taiwanese MSM. Single-visit point-of-care RNA testing would result in large reductions in HCV incidence and prevalence among MSM. Efficient risk-reduction strategies will need to be implemented alongside point-of-care testing to achieve HCV elimination among MSM in Taiwan.PMID:38695100 | DOI:10.1002/jia2.26251 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 2, 2024 Category: Infectious Diseases Authors: Huei-Jiuan Wu Sophy TingFang Shih Tanya L Applegate Jisoo A Kwon Evan B Cunningham Jason Grebely Richard T Gray Source Type: research

Exploring adolescent girls and young women's PrEP-user profiles: qualitative insights into differentiated PrEP delivery platform selection and engagement in Cape Town, South Africa
CONCLUSIONS: Market segmentation of AGYW characterizes different types of PrEP-users and has the potential to enhance tailored messaging and campaigns to reach specific segments, with the aim of improving sustained PrEP use and HIV prevention benefits.PMID:38695101 | DOI:10.1002/jia2.26254 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 2, 2024 Category: Infectious Diseases Authors: Elzette Rousseau Kathleen J Sikkema Robin F Julies Katelyn Mazer Gabrielle O'Malley Renee Heffron Jennifer F Morton Rachel Johnson Connie Celum Jared M Baeten Linda-Gail Bekker Source Type: research

Experiences of oral pre-exposure prophylaxis use among heterosexual men accessing sexual and reproductive health services in South Africa: a qualitative study
CONCLUSIONS: Our study reports on the experiences of heterosexual men accessing oral PrEP in real-world settings and contributes to the limited literature among this population. We highlight multiple levels which could be strengthened to improve men's PrEP use, including individual support, education among partners and communities, and addressing health system barriers to access.PMID:38695102 | DOI:10.1002/jia2.26249 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 2, 2024 Category: Infectious Diseases Authors: Fatima Abegail Cholo Siphokazi Dada Catherine Elizabeth Martin Saiqa Mullick Source Type: research

Urine tenofovir testing for real-time PrEP adherence feedback: a qualitative study involving transgender women in Uganda
CONCLUSIONS: Incorporating POC urine testing into routine PrEP adherence counselling was acceptable and potentially beneficial for TGW but required attention to context. Additional research is needed to identify effective strategies for optimizing adherence monitoring and counselling for this population.PMID:38695107 | DOI:10.1002/jia2.26255 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 2, 2024 Category: Infectious Diseases Authors: Andrew Mujugira Beyonce Karungi Jackson Mugisha Agnes Nakyanzi Olivia Nampewo Faith Naddunga Brenda Kamusiime Rogers Nsubuga Kikulwe R Nyanzi Timothy R Muwonge Monique A Wyatt Norma C Ware Monica Gandhi Jessica E Haberer Source Type: research

Prevalence and incidence of anal high-grade squamous intraepithelial lesions in a cohort of cisgender men and transgender women who have sex with men diagnosed and treated during acute HIV acquisition in Bangkok, Thailand
CONCLUSIONS: With antiretroviral therapy initiation during acute HIV acquisition, we found the prevalence of anal HSIL among cisgender men and transgender women who have sex with men to be similar to those without HIV. Subsequent anal HSIL incidence, although lower than that of those with chronic HIV acquisition, was still higher than that of those without HIV. Screening for and management of anal HSIL should be a crucial part of long-term HIV care for all MSM.PMID:38695517 | DOI:10.1002/jia2.26242 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - May 2, 2024 Category: Infectious Diseases Authors: Supanat Thitipatarakorn Nipat Teeratakulpisarn Siriporn Nonenoy Aphakan Klinsukontakul Sujittra Suriwong Jirat Makphol Piranun Hongchookiat Thanyapat Chaya-Ananchot Napasawan Chinlaertworasiri Pravit Mingkwanrungruang Carlo Sacdalan Kultida Poltavee Tippa Source Type: research

Injection network drivers of HIV prevention service utilization among people who inject drugs: results of a community-based sociometric network cohort in New Delhi, India
CONCLUSIONS: We found differential associative relationships between individual HIV prevention service engagement and the health or risk behaviours of direct and indirect alters. Characterizing network exposure beyond direct injecting partnerships provided important context on possible mechanisms of behavioural influence. Findings could be leveraged to design peer-based interventions that promote network diffusion of health-seeking behaviours.PMID:38632848 | PMC:PMC11024448 | DOI:10.1002/jia2.26241 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 18, 2024 Category: Infectious Diseases Authors: Neia S Prata Menezes Shruti H Mehta Amy Wesolowski Steven J Clipman Aylur K Srikrishnan Muniratnam S Kumar Katie J C Zook Gregory M Lucas Carl Latkin Sunil S Solomon Source Type: research

Injection network drivers of HIV prevention service utilization among people who inject drugs: results of a community-based sociometric network cohort in New Delhi, India
CONCLUSIONS: We found differential associative relationships between individual HIV prevention service engagement and the health or risk behaviours of direct and indirect alters. Characterizing network exposure beyond direct injecting partnerships provided important context on possible mechanisms of behavioural influence. Findings could be leveraged to design peer-based interventions that promote network diffusion of health-seeking behaviours.PMID:38632848 | DOI:10.1002/jia2.26241 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 18, 2024 Category: Infectious Diseases Authors: Neia S Prata Menezes Shruti H Mehta Amy Wesolowski Steven J Clipman Aylur K Srikrishnan Muniratnam S Kumar Katie J C Zook Gregory M Lucas Carl Latkin Sunil S Solomon Source Type: research

Social and structural drivers of HIV vulnerability among a respondent-driven sample of feminine and non-feminine presenting transgender women who have sex with men in Zimbabwe
CONCLUSIONS: Findings suggest that TGW, particularly feminine presenting TGW, experience social and structural inequities which may contribute to HIV vulnerability. Interventions aimed at addressing inequities, including trans competency training for providers and gender-affirming, psychosocial and legal support services for TGW, might mitigate risk.PMID:38627887 | PMC:PMC11021625 | DOI:10.1002/jia2.26231 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - April 17, 2024 Category: Infectious Diseases Authors: Lauren E Parmley Sophia S Miller Innocent Chingombe Munyaradzi Mapingure Owen Mugurungi John H Rogers Godfrey Musuka Chesterfield Samba Avi J Hakim Tiffany G Harris Source Type: research