Comprehensive characterization of stemness-related lncRNAs in triple-negative breast cancer identified a novel prognostic signature related to treatment outcomes, immune landscape analysis and therapeutic guidance: a silico analysis with in vivo experiments
Cancer stem cells (CSCs) and long non-coding RNAs (lncRNAs) are known to play a crucial role in the growth, migration, recurrence, and drug resistance of tumor cells, particularly in triple-negative breast can... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 4, 2024 Category: Research Authors: Min Zhang, Fangxu Zhang, Jianfeng Wang, Qian Liang, Weibing Zhou and Jian Liu Tags: Research Source Type: research
Differences of skin carotenoids and adherence to the Mediterranean Diet pattern in adults from Southern Italy and Dominican Republic
The measurement of the skin carotenoids using the Veggie Meter ® has emerged as a rapid objective method for assessing fruit and vegetable intake, highly recommended by the Mediterranean Diet (MD), which repres... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 4, 2024 Category: Research Authors: Giuseppina Augimeri, Manuel Soto, Fabrizio Ceraudo, Giovanna Caparello, Melisa Villegas Figueroa, Mirko Cesario, Lorenzo S. Caputi, Berniza Calder ón and Daniela Bonofiglio Tags: Research Source Type: research
Genetic association and causal relationship between multiple modifiable risk factors and autoimmune liver disease: a two-sample mendelian randomization study
This study comprehensively assessed the causal association bet... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 4, 2024 Category: Research Authors: Weize Gao, Chong Peng, Zhan Wang, Yongxin Li and Mingjun Liu Tags: Research Source Type: research
Correction to: Role of Hippo pathway dysregulation from gastrointestinal premalignant lesions to cancer
(Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 3, 2024 Category: Research Authors: Giulia Schiavoni, Beatrice Messina, Stefano Scalera, Lorenzo Memeo, Cristina Colarossi, Marzia Mare, Giovanni Blandino, Gennaro Ciliberto, Giulia Bon and Marcello Maugeri-Sacc à Tags: Correction Source Type: research
Integrative analyses of bulk and single-cell transcriptomics reveals the infiltration and crosstalk of cancer-associated fibroblasts as a novel predictor for prognosis and microenvironment remodeling in intrahepatic cholangiocarcinoma
Intrahepatic cholangiocarcinoma (ICC) is a highly malignant neoplasm and characterized by desmoplastic matrix. The heterogeneity and crosstalk of tumor microenvironment remain incompletely understood. (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 3, 2024 Category: Research Authors: Yan-Jie Zhong, Xi-Mei Luo, Fei Liu, Zhi-Qiang He, Si-Qi Yang, Wen-Jie Ma, Jun-Ke Wang, Yu-Shi Dai, Rui-Qi Zou, Ya-Fei Hu, Tian-Run Lv, Fu-Yu Li and Hai-Jie Hu Tags: Research Source Type: research
Impact of fundamental components of the Mediterranean diet on the microbiota composition in blood pressure regulation
The Mediterranean diet (MedDiet) is a widely studied dietary pattern reflecting the culinary traditions of Mediterranean regions. High adherence to MedDiet correlates with reduced blood pressure and lower card... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 3, 2024 Category: Research Authors: Ana Karina Zambrano, Santiago Cadena-Ullauri, Viviana A. Ruiz-Pozo, Rafael Tamayo-Trujillo, Elius Paz-Cruz, Patricia Guevara-Ram írez, Evelyn Frias-Toral and Daniel Simancas-Racines Tags: Review Source Type: research
Mechanism of action, potency and efficacy: considerations for cell therapies
One of the most challenging aspects of developing advanced cell therapy products (CTPs) is defining the mechanism of action (MOA), potency and efficacy of the product. This perspective examines these concepts ... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 2, 2024 Category: Research Authors: Carl G. Simon Jr., Erich H. Bozenhardt, Christina M. Celluzzi, David Dobnik, Melanie L. Grant, Uma Lakshmipathy, Thiana Nebel, Linda Peltier, Anthony Ratcliffe, James L. Sherley, Glyn N. Stacey, Rouzbeh R. Taghizadeh, Eddie H. P. Tan and Sandrine Vessilli Tags: Review Source Type: research
Correction to: Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer
(Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 2, 2024 Category: Research Authors: Jieping Qiu, Ying Xia, Yawei Bao, Jingjing Cheng, Lei Liu and Dong Qian Tags: Correction Source Type: research
Removal of endothelial surface-associated von villebrand factor suppresses accelerate datherosclerosis after myocardial infarction
Thromboinflammation involving platelet adhesion to endothelial surface-associated von Willebrand factor (VWF) has been implicated in the accelerated progression of non-culprit plaques after MI. The aim of this... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 1, 2024 Category: Research Authors: Koya Ozawa, William Packwood, Matthew A Muller, Yue Qi, Aris Xie, Oleg Varlamov, Owen J. McCarty, Dominic Chung, Jos é A. López and Jonathan R. Lindner Tags: Research Source Type: research
The potential and promise for clinical application of adoptive T cell therapy in cancer
Adoptive cell therapy has revolutionized cancer treatment, especially for hematologic malignancies. T cells are the most extensively utilized cells in adoptive cell therapy. Currently, tumor-infiltrating lymph... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 1, 2024 Category: Research Authors: Yinqi Li, Yeteng Zheng, Taiqing Liu, Chuanyun Liao, Guobo Shen and Zhiyao He Tags: Review Source Type: research
Genomic landscape and distinct molecular subtypes of primary testicular lymphoma
Primary testicular lymphoma (PTL) is a rare lymphoma predominantly occurring in the elderly male population. It is characterized by a limited response to treatment and a heightened tendency towards relapse. Hi... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - May 1, 2024 Category: Research Authors: Weilong Zhang, Ping Yang, Yaru Yang, Shuozi Liu, Yongdeng Xu, Chaoling Wu, Jing Wang, Cuiling Liu, Hui Liu, Shuangshuang Li, Wei Huang and Hongmei Jing Tags: Research Source Type: research
Potential value of CT-based comprehensive nomogram in predicting occult lymph node metastasis of esophageal squamous cell paralaryngeal nerves: a two-center study
The aim of this study is to construct a combined model that integrates radiomics, clinical risk factors and machine learning algorithms to predict para-laryngeal lymph node metastasis in esophageal squamous ce... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - April 30, 2024 Category: Research Authors: Ting Xue, Xinyi Wan, Taohu Zhou, Qin Zou, Chao Ma and Jieqiong Chen Tags: Research Source Type: research
Correction: Implementation of genomic medicine for rare disease in a tertiary healthcare system: Mayo Clinic Program for Rare and Undiagnosed Diseases (PRaUD)
(Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - April 30, 2024 Category: Research Authors: Filippo Pinto e Vairo, Jennifer L. Kemppainen, Carolyn R. Rohrer Vitek, Denise A. Whalen, Kayla J. Kolbert, Kaitlin J. Sikkink, Sarah A. Kroc, Teresa Kruisselbrink, Gabrielle F. Shupe, Alyssa K. Knudson, Elizabeth M. Burke, Elle C. Loftus, Lorelei A. Band Tags: Correction Source Type: research
The association of ROS1 mutation with cancer immunity and its impact on the efficacy of pan-cancer immunotherapy
(Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - April 30, 2024 Category: Research Authors: Yingying Li, Hong Zhao, Jinyuan Huang, Huimeng Yan and Bin Zhao Tags: Letter to the Editor Source Type: research
Developing and validating a clinlabomics-based machine-learning model for early detection of retinal detachment in patients with high myopia
Retinal detachment (RD) is a vision-threatening disorder of significant severity. Individuals with high myopia (HM) face a 2 to 6 times higher risk of developing RD compared to non-myopes. The timely identific... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - April 30, 2024 Category: Research Authors: Shengjie Li, Meiyan Li, Jianing Wu, Yingzhu Li, Jianping Han, Yunxiao Song, Wenjun Cao and Xingtao Zhou Tags: Research Source Type: research
