LncRNA PART1 Attenuates Myocardial Ischemia-Reperfusion Injury by Regulating TFAP2C/DUSP5 Axis via miR-302a-3p
CONCLUSION: PART1 improved the autophagy and apoptosis in H/R-exposed AC16 cells through miR-302a-3p/TFAP2C/DUSP5 axis, which might provide novel targets for MIRI treatment.PMID:38654453 | DOI:10.4070/kcj.2023.0131 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Min Zeng Xin Wei Jinchao Zhou Siqi Luo Source Type: research
Neuromodulation for Atrial Fibrillation Control
Korean Circ J. 2024 Mar 18. doi: 10.4070/kcj.2024.0050. Online ahead of print.ABSTRACTTrigger and functional substrate are related to the tone of autonomic nervous system, and the role of the autonomic nerve is more significant in paroxysmal atrial fibrillation (AF) compared to non-paroxysmal AF. We have several options for neuromodulation to help to manage patients with AF. Neuromodulation targets can be divided into efferent and afferent pathways. On the efferent side, block would be an intuitive approach. However, permanent block is hard to achieve due to completeness of the procedure and reinnervation issues. Temporary...
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Seil Oh Source Type: research
Lower Atrial Fibrillation Risk With Sodium-Glucose Cotransporter 2 Inhibitors Than With Dipeptidyl Peptidase-4 Inhibitors in Individuals With Type 2 Diabetes: A Nationwide Cohort Study
CONCLUSIONS: In this nationwide cohort study of individuals with type 2 diabetes, treatment with SGLT2i was associated with a lower risk of AF compared with treatment with DPP-4i.PMID:38654455 | DOI:10.4070/kcj.2023.0234 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Min Kim Kyoung Hwa Ha Junyoung Lee Sangshin Park Kyeong Seok Oh Dae-Hwan Bae Ju Hee Lee Sang Min Kim Woong Gil Choi Kyung-Kuk Hwang Dong-Woon Kim Myeong-Chan Cho Dae Jung Kim Jang-Whan Bae Source Type: research
COVID-19 Vaccination-Related Myocarditis: What We Learned From Our Experience and What We Need to Do in The Future
Korean Circ J. 2024 Apr 1. doi: 10.4070/kcj.2024.0065. Online ahead of print.ABSTRACTCoronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has led to a global health crisis with substantial mortality and morbidity. To combat the COVID-19 pandemic, various vaccines have been developed, but unexpected serious adverse events including vaccine-induced thrombotic thrombocytopenia, carditis, and thromboembolic events have been reported and became a huddle for COVID-19 vaccination. Vaccine-related myocarditis (VRM) is a rare but significant adverse event associated primarily with mRNA vacci...
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Jae-Hyeong Park Kye Hun Kim Source Type: research
Beta Blockers in Contemporary Cardiology: Is It Better to Cast Them Out?
Korean Circ J. 2024 Apr;54(4):165-171. doi: 10.4070/kcj.2023.0209.ABSTRACTBeta blockers are one of the commonest prescription drugs in medicine and they have been thought to revolutionize the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) in the last century. In addition to HFrEF, they are prescribed for a variety of diseases in cardiology from hypertension to HF, angina, and stable coronary artery disease (CAD). The increased prescription of beta blockers in conditions like HF with preserved ejection fraction (HFpEF), and stable CAD may be doing more harm than good as per the data we have so far. T...
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Javaid Ahmad Dar John Roshan Jacob Source Type: research
Dronedarone Attenuates Ang II-Induced Myocardial Hypertrophy Through Regulating SIRT1/FOXO3/PKIA Axis
CONCLUSIONS: Dronedarone alleviated MH through mediating SIRT1/FOXO3/PKIA axis, which provide more evidences for dronedarone against MH.PMID:38654563 | PMC:PMC11040268 | DOI:10.4070/kcj.2023.0197 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Cheng Chen Song Hu Heng-Jing Hu Zhi-Xuan Liu Xin-Teng Wu Tao Zou Hua Su Source Type: research
Pleiotropic Effect of Dronedarone Beyond Antiarrhythmic Agent: Reduction of Hypertrophy
Korean Circ J. 2024 Apr;54(4):187-188. doi: 10.4070/kcj.2024.0067.NO ABSTRACTPMID:38654564 | PMC:PMC11040269 | DOI:10.4070/kcj.2024.0067 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Jung-Joon Cha Source Type: research
The Association of CHADS-P2A2RC Risk Score With Clinical Outcomes in Patients Taking P2Y12 Inhibitor Monotherapy After 3 Months of Dual Antiplatelet Therapy Following Percutaneous Coronary Intervention
CONCLUSIONS: The CHADS-P2A2RC risk score is valuable in discriminating high-ischemic-risk patients. Even in such patients with a high risk of ischemic events, P2Y12 inhibitor monotherapy was associated with a lower incidence of bleeding without increased risk of ischemic events compared with prolonged DAPT.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT02079194.PMID:38654565 | PMC:PMC11040264 | DOI:10.4070/kcj.2023.0268 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Pil Sang Song Seok-Woo Seong Ji-Yeon Kim Soo Yeon An Mi Joo Kim Kye Taek Ahn Seon-Ah Jin Jin-Ok Jeong Jeong Hoon Yang Joo-Yong Hahn Hyeon-Cheol Gwon Woo Jin Jang Hyuck Jun Yoon Jang-Whan Bae Woong Gil Choi Young Bin Song Source Type: research
Requirements of a Usable Scoring System for Risk Stratification in Patients With Coronary Artery Disease
Korean Circ J. 2024 Apr;54(4):201-202. doi: 10.4070/kcj.2024.0082.NO ABSTRACTPMID:38654566 | PMC:PMC11040265 | DOI:10.4070/kcj.2024.0082 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Sung Soo Kim Hyun Kuk Kim Source Type: research
The Effects of Radiofrequency Catheter Ablation for Atrial Fibrillation on Right Ventricular Function
CONCLUSIONS: RV systolic function is more impaired in patients with PeAF and LSPeAF than in those with PAF. RV systolic function is more improved after RFCA in patients with PeAF than in those with PAF or LSPeAF.PMID:38654567 | PMC:PMC11040267 | DOI:10.4070/kcj.2023.0312 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Minkwan Kim Jae-Sun Uhm Je-Wook Park SungA Bae In Hyun Jung Seok-Jae Heo Daehoon Kim Hee Tae Yu Tae-Hoon Kim Boyoung Joung Moon-Hyoung Lee Source Type: research
Preserving the Right Ventricular Function: Early Rhythm Control Through Ablation of Persistent Atrial Fibrillation
Korean Circ J. 2024 Apr;54(4):218-220. doi: 10.4070/kcj.2024.0102.NO ABSTRACTPMID:38654568 | PMC:PMC11040262 | DOI:10.4070/kcj.2024.0102 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Min-Su Jung Hyoung-Seob Park Source Type: research
Cardiomyopathy Without Amyloid Deposit in Systemic Light Chain Deposition Disease
Korean Circ J. 2024 Apr;54(4):221-222. doi: 10.4070/kcj.2024.0022.NO ABSTRACTPMID:38654569 | PMC:PMC11040263 | DOI:10.4070/kcj.2024.0022 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Bo Eun Park Se Yong Jang Yoon Jung Park Myung Hwan Bae Jang Hoon Lee Dong Heon Yang Hun Sik Park Yongkeun Cho Source Type: research
LncRNA PART1 Attenuates Myocardial Ischemia-Reperfusion Injury by Regulating TFAP2C/DUSP5 Axis via miR-302a-3p
CONCLUSION: PART1 improved the autophagy and apoptosis in H/R-exposed AC16 cells through miR-302a-3p/TFAP2C/DUSP5 axis, which might provide novel targets for MIRI treatment.PMID:38654453 | DOI:10.4070/kcj.2023.0131 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Min Zeng Xin Wei Jinchao Zhou Siqi Luo Source Type: research
Neuromodulation for Atrial Fibrillation Control
Korean Circ J. 2024 Mar 18. doi: 10.4070/kcj.2024.0050. Online ahead of print.ABSTRACTTrigger and functional substrate are related to the tone of autonomic nervous system, and the role of the autonomic nerve is more significant in paroxysmal atrial fibrillation (AF) compared to non-paroxysmal AF. We have several options for neuromodulation to help to manage patients with AF. Neuromodulation targets can be divided into efferent and afferent pathways. On the efferent side, block would be an intuitive approach. However, permanent block is hard to achieve due to completeness of the procedure and reinnervation issues. Temporary...
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Seil Oh Source Type: research
Lower Atrial Fibrillation Risk With Sodium-Glucose Cotransporter 2 Inhibitors Than With Dipeptidyl Peptidase-4 Inhibitors in Individuals With Type 2 Diabetes: A Nationwide Cohort Study
CONCLUSIONS: In this nationwide cohort study of individuals with type 2 diabetes, treatment with SGLT2i was associated with a lower risk of AF compared with treatment with DPP-4i.PMID:38654455 | DOI:10.4070/kcj.2023.0234 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Min Kim Kyoung Hwa Ha Junyoung Lee Sangshin Park Kyeong Seok Oh Dae-Hwan Bae Ju Hee Lee Sang Min Kim Woong Gil Choi Kyung-Kuk Hwang Dong-Woon Kim Myeong-Chan Cho Dae Jung Kim Jang-Whan Bae Source Type: research
