Does electrophysical agents work for cellulite treatment? a systematic review of clinical trials
Conclusions: Our findings indicate that the quality of evidence from clinical studies on the use of electrophysical agents for cellulite treatment remains subpar. Further studies with robust experimental designs and more precise assessment techniques are necessary. While our study does not refute the effectiveness of the techniques used for cellulite treatment, it underscores the need for additional well-designed trials. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - May 2, 2024 Category: Laser Surgery Source Type: research

Enhancing nerve regeneration in infraorbital nerve injury rat model: effects of vitamin B complex and photobiomodulation
AbstractOrofacial nerve injuries may result in temporary or long-term loss of sensory function and decreased quality of life in patients. B vitamins are required for DNA synthesis and the repair and maintenance of phospholipids. In particular, vitamins B1, B6, and B12 are essential for neuronal function. Deficiency in vitamin B complex (VBC) has been linked to increased oxidative stress, inflammation and demyelination. Photobiomodulation (PBM) has antioxidant activity and is neuroprotective. In addition, a growing literature attests to the positive effects of PBM on nerve repair. To assess the effect of PBM and VBC on rege...
Source: Lasers in Medical Science - April 29, 2024 Category: Laser Surgery Source Type: research

Definition of refractory melasma and its treatment: a review
In conclusion, we were able to provide a rough definition of refractory melasma and list the available therapies. According to the literature, the most prevalent treat ment is laser combination therapy. However, laser treatment should be considered only after topical agents and chemical peeling have failed. Considering its side effects, efficacy, and safety, oral TXA may be a better option, but more research is needed to make a firm conclusion. Moreover, maintenan ce therapy is required after treatment. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - April 29, 2024 Category: Laser Surgery Source Type: research

The phenomenon of skin contraction in CO2 LASER surgical incisions using superpulse and continuous emission mode – preliminary study
This study suggests that the use of the Continuous mode of LASER emission, regardless of the power used, is associated with a higher level of final skin contraction.Trial registration number and date of registration for prospectively registered trialsProject approval registration number by the Research and Teaching Ethics Committee (CEIE),Faculty of Veterinary Medicine —University of Lisbon (FMV_ULisboa), Lisboa—Portugal, N/Refª 015/2022. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - April 28, 2024 Category: Laser Surgery Source Type: research

Effectiveness of photobiomodulation therapy in the treatment of patients with an ankle sprain: a systematic review and meta-analysis
ConclusionPBMT is quite effective for patients with an ankle sprain. PBMT showed high effect size with a moderate level of evidence on pain intensity. The lack of significant effects of PBMT on function and edema with low level of evidence limit the confidence to the current results and recommend further large high-quality studies with higher PBMT intensity and fluency for standardisation of the irradiation parameters and treatment protocol.RegistrationPROSPERO registration number (CRD42021292930). (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - April 26, 2024 Category: Laser Surgery Source Type: research

Advantages of the co2 laser use in the rare condition of nasal mucosa squamous cell carcinoma surgery in dogs —a clinical prospective study
AbstractNasal mucosa tumors are an uncommon process and very dificult to work on with surgery. Radiotherapy associated or not with chemotherapy is the standard method to treat the disease. However, its access it is in the majority of the case not possible, making the surgery the best choice to try to achieve the patient's control. The anatomy of the region makes the complete surgical resection very difficult to achieve using the common and conventional blade scalpel surgery.  The study features the advantages of using a CO2 laser to perform nasal mucosa carcinoma surgery in 6 dogs (N  = 6). For the work we used an Aes...
Source: Lasers in Medical Science - April 25, 2024 Category: Laser Surgery Source Type: research

Comment to: Dusting efficacy between the regular setting of holmium laser (Ho:YAG) versus vapor tunnel pulse modality for non-complex kidney stones
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - April 25, 2024 Category: Laser Surgery Source Type: research

Phase-locked µPIV analysis of flow dynamics in a simulated root canal with different laser-activated irrigations
Conclusion: Elevating the activation energy can boost the peak flushing veloci ty and the maximum WSS, thereby enhancing irrigation efficiency. Given the same activation energy, PIPS outperforms MSP. Additionally, increasing the activation frequency may be an effective strategy to improve irrigation performance further. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - April 24, 2024 Category: Laser Surgery Source Type: research

Intense pulsed light therapy for ocular surface diseases
AbstractIntense pulsed light (IPL) is a non-laser, high-intensity light source that has been shown to play a valuable role in dermatology and has been adopted in ophthalmology for treating meibomian gland dysfunction (MGD). In this review, we discuss the mechanism of action of IPL, including its benefits in ophthalmology. IPL therapy has been shown to improve tear film stability, meibomian gland (MG) function, and subjective symptoms of ocular dryness in MGD patients. Moreover, emerging evidence suggests that IPL therapy is beneficial for other ocular surface diseases, such as blepharitis and chalazia. Hence, it can be inf...
Source: Lasers in Medical Science - April 24, 2024 Category: Laser Surgery Source Type: research

755-nm picosecond laser plus topical 20% azelaic acid compared to topical 20% azelaic acid alone for the treatment of melasma: a randomized, split-face and controlled trial
Conclusion: The additional use of picosecond laser therapy showed no clinical difference except for subtle differences detected by RCM assessments.The study was registered in the Chinese Clinical Trial Registry (ChiCTR2100051294; 18 September 2021). (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - April 24, 2024 Category: Laser Surgery Source Type: research

Photobiomodulation in promoting increased Skin Flap Viability: a systematic review of animal studies
AbstractNecrosis is common in skin flap surgeries. Photobiomodulation, a noninvasive and effective technique, holds the potential to enhance microcirculation and neovascularization. As such, it has emerged as a viable approach for mitigating the occurrence of skin flap necrosis. The aim of this systematic review was to examine the scientific literature considering the use of photobiomodulation to increase skin-flap viability. The preferred reporting items for systematic reviews and meta-analyses (PRISMA), was used to conducted systematic literature search in the databases PubMed, SCOPUS, Elsevier and, Scielo on June 2023. ...
Source: Lasers in Medical Science - April 22, 2024 Category: Laser Surgery Source Type: research

Analysis of modified ilib therapy in patients submitted to plastic surgery
AbstractThe sample comprised 44 volunteers who had undergone some surgical procedure and were equally divided into four groups. G1 started the therapy 24  h after the surgical procedure with the device off. G2 followed the same time pattern, 24 h, but with the device turned on. G3 and G4 started therapy three days after the surgical procedure; in G3, the device was turned off, and in G4, the device remained on during therapy; each session lasted 30  min, using 660 nm (red), energy 180 J. For all groups, the therapy started with daily use for seven days and followed the interval use of three times a week until complete...
Source: Lasers in Medical Science - April 22, 2024 Category: Laser Surgery Source Type: research

Bio-thermal response during laser haemorrhoidoplasty: an exclusive analytical and numerical approach for theoretical investigation
AbstractHaemorrhoidal disease is identified by declension of the inflamed and bleeding of vascular tissues of the anal canal. Traditionally, haemorrhoids are associated with chronic  constipation and the most common symptoms are irritation in anus region, pain and discomfort, swelling around anus, tender lumps around the anus and rectal bleeding (depending upon the grade of haemorrhoid). Among the several conventional treatment procedures (commonly mentioned as, rubber band li tigation, sclerotherapy and electrotherapy), laser haemorrhoidoplasty is an out-patient and less-invasive laparoscopic procedure. From literature s...
Source: Lasers in Medical Science - April 22, 2024 Category: Laser Surgery Source Type: research

Clinical and ex-vivo effect of LASERs on prevention of early-enamel caries: systematic review & amp; meta-analyses
AbstractTo investigate the in vivo and in situ effect of different types of lasers in prevention of enamel demineralization in high caries risk cases (around orthodontic brackets, around restoration and in caries susceptible pits and fissures). PubMed was searched using the following keyword sequence; (Laser therapy OR laser irradiation OR laser application) AND (enamel caries prevention OR enamel demineralization OR enamel remineralization OR early enamel caries OR early-enamel caries OR enamel resistance OR enamel decalcification OR white spot lesions WSLs OR incipient lesion OR enamel decay OR enamel Dissolution OR enam...
Source: Lasers in Medical Science - April 18, 2024 Category: Laser Surgery Source Type: research

Deep learning automatically assesses 2- µm laser-induced skin damage OCT images
AbstractThe present study proposed a noninvasive, automated, in vivo assessment method based on optical coherence tomography (OCT) and deep learning techniques to qualitatively and quantitatively analyze the biological effects of 2- µm laser-induced skin damage at different irradiation doses. Different doses of 2-µm laser irradiation established a mouse skin damage model, after which the skin-damaged tissues were imaged non-invasively in vivo using OCT. The acquired images were preprocessed to construct the dataset required f or deep learning. The deep learning models used were U-Net, DeepLabV3+, PSP-Net, and HR-Net, and...
Source: Lasers in Medical Science - April 18, 2024 Category: Laser Surgery Source Type: research