Are there new relevant therapeutic endpoints in the modern era of the BCR::ABL1 tyrosine kinase inhibitors in chronic myeloid leukemia?
Leukemia, Published online: 26 March 2024; doi:10.1038/s41375-024-02229-3Are there new relevant therapeutic endpoints in the modern era of the BCR::ABL1 tyrosine kinase inhibitors in chronic myeloid leukemia? (Source: Leukemia)
Source: Leukemia - March 26, 2024 Category: Hematology Authors: Hagop Kantarjian Susan Branford Massimo Breccia Jorge Cortes Fadi G. Haddad Andreas Hochhaus Timothy Hughes Ghayas C. Issa Elias Jabbour Franck E. Nicolini Koji Sasaki Francois Xavier-Mahon Source Type: research

The Eμ-Ret mouse is a novel model of hyperdiploid B-cell acute lymphoblastic leukemia
Leukemia, Published online: 22 March 2024; doi:10.1038/s41375-024-02221-xThe Eμ-Ret mouse is a novel model of hyperdiploid B-cell acute lymphoblastic leukemia (Source: Leukemia)
Source: Leukemia - March 22, 2024 Category: Hematology Authors: Ali Farrokhi Tanmaya Atre Jenna Rever Mario Fidanza Wendy Duey Samuel Salitra Junia Myung Meiyun Guo Sumin Jo Anuli Uzozie Fatemeh Baharvand Nina Rolf Franziska Auer Julia Hauer Stephan A. Grupp Patrice Eydoux Philipp F. Lange Alix E. Seif Christopher A. Source Type: research

Measurable residual disease quantification in adult patients with KMT2A-rearranged acute lymphoblastic leukemia
Leukemia, Published online: 22 March 2024; doi:10.1038/s41375-024-02209-7Measurable residual disease quantification in adult patients with KMT2A-rearranged acute lymphoblastic leukemia (Source: Leukemia)
Source: Leukemia - March 22, 2024 Category: Hematology Authors: Thomas Burmeister Aeint-Steffen Str öh Britta Kehden Heiko Trautmann Claus Meyer Rolf Marschalek Patrizia Larghero Stefan Schwartz Bj örn Steffen Bernd Spriewald Thomas Heinicke Nadja J äkel J örg Westermann Kathrin Nachtkamp Andreas Viardot Max S. To Source Type: research

Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche
Leukemia, Published online: 21 March 2024; doi:10.1038/s41375-024-02226-6Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche (Source: Leukemia)
Source: Leukemia - March 21, 2024 Category: Hematology Authors: Susann Winter Katharina S. G ötze Judith S. Hecker Klaus H. Metzeler Borhane Guezguez Kevin Woods Hind Medyouf Alexander Sch äffer Marc Schmitz Rebekka Wehner Ingmar Glauche Ingo Roeder Martina Rauner Lorenz C. Hofbauer Uwe Platzbecker Source Type: research

Impaired binding affinity of YTHDC1 with METTL3/METTL14 results in R-loop accumulation in myelodysplastic neoplasms with DDX41 mutation
Leukemia, Published online: 21 March 2024; doi:10.1038/s41375-024-02228-4Impaired binding affinity of YTHDC1 with METTL3/METTL14 results in R-loop accumulation in myelodysplastic neoplasms with DDX41 mutation (Source: Leukemia)
Source: Leukemia - March 21, 2024 Category: Hematology Authors: Won Chan Hwang Kibeom Park Silvia Park Na Young Cheon Ja Yil Lee Taejoo Hwang Semin Lee Jong-Mi Lee Min Kyung Ju Joo Rak Lee Yong-Rim Kwon Woo-Lam Jo Myungshin Kim Yoo-Jin Kim Hongtae Kim Source Type: research

Treatment and survival for patients with localized primary ocular adnexal extranodal marginal zone lymphoma
Leukemia, Published online: 19 March 2024; doi:10.1038/s41375-024-02227-5Treatment and survival for patients with localized primary ocular adnexal extranodal marginal zone lymphoma (Source: Leukemia)
Source: Leukemia - March 19, 2024 Category: Hematology Authors: Lin-Rui Gao Xin Li Xinyue Wang Yuanzheng Liang Yunpeng Wu Xiao-Li Feng Wei Rao Xin Liu Yong-Wen Song Hui Fang Bo Chen Jing Jin Yue-Ping Liu Hao Jing Yuan Tang Ning-Ning Lu Shu-Lian Wang Ye-Xiong Li Liang Wang Shu-Nan Qi Source Type: research

Beyond the marrow: insights from comprehensive next-generation sequencing of extramedullary multiple myeloma tumors
Leukemia, Published online: 16 March 2024; doi:10.1038/s41375-024-02206-wBeyond the marrow: insights from comprehensive next-generation sequencing of extramedullary multiple myeloma tumors (Source: Leukemia)
Source: Leukemia - March 16, 2024 Category: Hematology Authors: T. Jelinek D. Zihala T. Sevcikova A. Anilkumar Sithara V. Kapustova H. Sahinbegovic O. Venglar L. Muronova L. Broskevicova S. Nenarokov D. Bilek T. Popkova H. Plonkova J. Vrana V. Zidlik P. Hurnik M. Havel M. Hrdinka Z. Chyra G. Stracquadanio M. Simicek R Source Type: research

Differential in vivo roles of Mpl cytoplasmic tyrosine residues in murine hematopoiesis and myeloproliferative disease
Leukemia, Published online: 15 March 2024; doi:10.1038/s41375-024-02219-5Differential in vivo roles of Mpl cytoplasmic tyrosine residues in murine hematopoiesis and myeloproliferative disease (Source: Leukemia)
Source: Leukemia - March 15, 2024 Category: Hematology Authors: Kira Behrens Maria Kauppi Elizabeth M. Viney Andrew J. Kueh Craig D. Hyland Tracy A. Willson Liam Salleh Carolyn A. de Graaf Jeffrey J. Babon Marco J. Herold Nicos A. Nicola Warren S. Alexander Source Type: research

CD22 CAR T cells demonstrate high response rates and safety in pediatric and adult B-ALL: Phase 1b results
Leukemia, Published online: 15 March 2024; doi:10.1038/s41375-024-02220-yCD22 CAR T cells demonstrate high response rates and safety in pediatric and adult B-ALL: Phase 1b results (Source: Leukemia)
Source: Leukemia - March 15, 2024 Category: Hematology Authors: Liora M. Schultz Nikeshan Jeyakumar Anne Marijn Kramer Bita Sahaf Hrishi Srinagesh Parveen Shiraz Neha Agarwal Mark Hamilton Courtney Erickson Ashley Jacobs Jennifer Moon Christina Baggott Sally Arai Sushma Bharadwaj Laura J. Johnston Michaela Liedtke Rob Source Type: research

NFKBIE mutations are selected by the tumor microenvironment and contribute to immune escape in chronic lymphocytic leukemia
Leukemia, Published online: 15 March 2024; doi:10.1038/s41375-024-02224-8NFKBIE mutations are selected by the tumor microenvironment and contribute to immune escape in chronic lymphocytic leukemia (Source: Leukemia)
Source: Leukemia - March 15, 2024 Category: Hematology Authors: Alice Bonato Supriya Chakraborty Riccardo Bomben Giulia Canarutto Giulia Felician Claudio Martines Antonella Zucchetto Federico Pozzo Marija Vujovikj Jerry Polesel Annalisa Chiarenza Maria Ilaria Del Principe Giovanni Del Poeta Giovanni D ’Arena Roberto Source Type: research

Flow cytometric analysis of peripheral blood neutrophil myeloperoxidase expression in myelodysplastic neoplasms
Leukemia, Published online: 14 March 2024; doi:10.1038/s41375-024-02223-9Flow cytometric analysis of peripheral blood neutrophil myeloperoxidase expression in myelodysplastic neoplasms (Source: Leukemia)
Source: Leukemia - March 14, 2024 Category: Hematology Authors: Tatiana Raskovalova Marie-Christine Jacob Sophie Park Source Type: research

Allogeneic haematopoietic cell transplantation for advanced systemic mastocytosis: Best practice recommendations on behalf of the EBMT Practice Harmonisation and Guidelines Committee
Leukemia, Published online: 12 March 2024; doi:10.1038/s41375-024-02182-1Allogeneic haematopoietic cell transplantation for advanced systemic mastocytosis: Best practice recommendations on behalf of the EBMT Practice Harmonisation and Guidelines Committee (Source: Leukemia)
Source: Leukemia - March 12, 2024 Category: Hematology Authors: Donal P. McLornan Tomasz Czerw Gandhi Damaj Mark Ethell Carmelo Gurnari Juan Carlos Hern ández-Boluda Nicola Polverelli Juliana Schwaab Katja Sockel Greco Raffaella Francesco Onida Isabel S ánchez-Ortega Giorgia Battipaglia Chiara Elena Jason Gotlib And Source Type: research

Why are not all eligible chronic myeloid leukemia patients willing to attempt tyrosine kinase inhibitor discontinuation? A Czech nationwide analysis related to the TKI stopping trial HALF
Leukemia, Published online: 12 March 2024; doi:10.1038/s41375-024-02215-9Why are not all eligible chronic myeloid leukemia patients willing to attempt tyrosine kinase inhibitor discontinuation? A Czech nationwide analysis related to the TKI stopping trial HALF (Source: Leukemia)
Source: Leukemia - March 12, 2024 Category: Hematology Authors: Daniela Žáčková Luk áš Semerád Edgar Faber Hana Klamov á Luk áš Stejskal Petra B ělohlávková Michal Karas Eduard Cmunt Olga Černá Ji řina Procházková Petra Čičátková Ane žka Kvetková Tom áš Horňák Ivana Skoumalov á Dana Srbov Source Type: research

Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity
Leukemia, Published online: 11 March 2024; doi:10.1038/s41375-024-02211-zMutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity (Source: Leukemia)
Source: Leukemia - March 11, 2024 Category: Hematology Authors: Matthew Schwede Katharina Jahn Jack Kuipers Linde A. Miles Robert L. Bowman Troy Robinson Ken Furudate Hidetaka Uryu Tomoyuki Tanaka Yuya Sasaki Asiri Ediriwickrema Brooks Benard Andrew J. Gentles Ross Levine Niko Beerenwinkel Koichi Takahashi Ravindra Ma Source Type: research

STAT3 protects hematopoietic stem cells by preventing activation of a deleterious autocrine type-I interferon response
Leukemia, Published online: 11 March 2024; doi:10.1038/s41375-024-02218-6STAT3 protects hematopoietic stem cells by preventing activation of a deleterious autocrine type-I interferon response (Source: Leukemia)
Source: Leukemia - March 11, 2024 Category: Hematology Authors: Bhakti Patel Yifan Zhou Rachel L. Babcock Feiyang Ma M. Anna Zal Dhiraj Kumar Yusra B. Medik Laura M. Kahn Josu é E. Pineda Elizabeth M. Park Sarah M. Schneider Ximing Tang Maria Gabriela Raso Collene R. Jeter Tomasz Zal Karen Clise-Dwyer Khandan Keyomar Source Type: research