Predictive values of relative fat mass and body mass index on cardiovascular health in community-dwelling older adults: Results from the Longevity Check-up (Lookup) 7+
Cardiovascular disease (CVD) is the leading cause of death and non-communicable diseases worldwide [1,2]. Cardiovascular risk factors (CRFs) such as excess body weight, high blood pressure (BP), diabetes, high low-density lipoprotein cholesterol, and active smoking are responsible for more than half of new CVD diagnoses and one fifth of 10-year mortality [3]. Assessing and managing cardiovascular risk is particularly relevant in older adults, as advancing age itself is a predisposing factor for CVD [4]. (Source: Maturitas)
Source: Maturitas - May 1, 2024 Category: Primary Care Authors: Stefano Cacciatore, Riccardo Calvani, Emanuele Marzetti, Helio Jos é Coelho-Júnior, Anna Picca, Alberto Emanuele Fratta, Ilaria Esposito, Matteo Tosato, Francesco Landi Tags: Original article Source Type: research
Adding more beans to the US typical dietary pattern can lead to greater intake of shortfall nutrients and a higher diet quality in younger and older adults
United States (US) dietary guidance sets forth evidence-based recommendations on what every American should consume to meet nutrient requirements and reduce chronic disease risk. The process is completed every five years and is jointly accomplished via the US Department of Agriculture (USDA) and Health and Human Services [1]. Current dietary patterns in the American population continue to fall short of meeting recommendations set forth by the 2020 –2025 Dietary Guidelines for Americans (DGA) [2]. (Source: Maturitas)
Source: Maturitas - April 29, 2024 Category: Primary Care Authors: Yanni Papanikolaou, Joanne Slavin, Sofia Papanikolaou, Victor L. Fulgoni Tags: Original article Source Type: research
Weight gain during midlife: Does race/ethnicity influence risk?
Analysis of the United States National Health and Nutrition Examination Survey (NHANES) from 1999 to 2008 by Flegal et al. found a progressive increase in the prevalence of obesity (defined as a body mass index ≥30) for adults of all ages. Most notable was the prevalence of obesity in women aged 40–59 with the 2007–2008 prevalence in non-Hispanic Caucasian women at 35.7 %, while for non-Hispanic African American and Mexican American women the values were close to 50 % (51.7 % and 48.9 % respe ctively). (Source: Maturitas)
Source: Maturitas - April 29, 2024 Category: Primary Care Authors: Patress Ann Persons, Lesley Williams, Heather Fields, Sneha Mishra, Rajal Mehta Tags: Review article Source Type: research
The relationship between religious affiliation and menopause symptoms and attitudes in United States women
Menopause a is key phase in female reproductive health and can result in bothersome symptoms. Natural menopause is defined as the permanent cessation of menstruation due to the loss of follicular activity in the ovaries, typically between the ages of 45 and 58 years [1]. Hot flashes and difficulty sleeping are commonly reported symptoms, and sexual dysfunction is a commonly reported diagnosis by women in this age group [2]. Hot flashes last an average of 7 years after natural menopause, but in some cases longer, and are characterized by a transient r ise in skin temperature and heart rate [2]. (Source: Maturitas)
Source: Maturitas - April 28, 2024 Category: Primary Care Authors: Annika Agarwal, Holly N. Thomas Tags: Original article Source Type: research
Antidepressant use and ovarian cancer risk: Evidence from nationwide studies with > 14,000 cases from Denmark and Sweden
Depression is estimated to have affected 4.4 % of the global population in 2015 (1). The condition has a high recurrence rate and in most cases require medium- to long-term treatment. The number of prescriptions for antidepressants has been increasing substantially over the last decades (2), and it is of public health priority to investigat e the epidemiology of potential side effects in a systematic fashion. Commonly prescribed antidepressants include tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs). (Source: Maturitas)
Source: Maturitas - April 24, 2024 Category: Primary Care Authors: Guoqiao Zheng, Louise Baandrup, Jiangrong Wang, Rasmus Hertzum-Larsen, Charlotte Gerd Hannibal, Lina S. M ørch, Mette Tuxen Faber, Karin Sundström, Susanne K. Kjær Tags: Original Article Source Type: research
Insights into the vulvar component of the genitourinary syndrome of menopause (GSM)
Genital, urinary and sexual symptoms are common in elderly women because menopausal hypoestrogenism interacts with both reduced androgen circulating levels and degenerative processes driven by age, leading to anatomical and functional modifications in urogenital tissues [1]. Clinical presentations are highly heterogeneous in terms of type, severity and localization of symptoms, as well as influence on quality of life (QoL), which greatly varies according to a multitude of bio-psycho-social determinants [2]. (Source: Maturitas)
Source: Maturitas - April 24, 2024 Category: Primary Care Authors: Laura Cucinella, Lara Tiranini, Chiara Cassani, Ellis Martini, Andrea Cumetti, Stefano Memoli, Sara Tedeschi, Rossella E. Nappi Tags: Review article Source Type: research
Menopause experiences in sexual minority women and non-binary people
By 2060, there will be an estimated 5 million sexual and gender minority adults who are 50+ years old in the United States [1]. Lesbian/gay, bisexual, and queer-identified1 cisgender women, to whom we refer as sexual minority women (SMW), and non-binary people are resilient and diverse. Despite making substantial strides towards achieving visibility and acceptance, the healthcare experiences of these communities remain overwhelmingly characterized by challenges, disparities, and unmet needs. Additionally, SMW and non-binary people continue to be excluded or overlooked in medical research even as population numbers grow. (Source: Maturitas)
Source: Maturitas - April 24, 2024 Category: Primary Care Authors: Talia Sobel, Donya Derakshani, Jennifer A. Vencill Tags: Review article Source Type: research
Comparison of promestriene with vaginal fractional CO2 laser and radiofrequency treatments of genitourinary syndrome of menopause
Life expectancy has been increasing worldwide in the last decades and at least one third of women's life will be lived in the postmenopausal period [1]; thus, many suffering of the Genitourinary Syndrome of Menopause (GSM) [2,3]; This is a chronic and progressive female condition involving several lower genital tract signs and symptoms, including dyspareunia, vaginal dryness, itching, burning and also urinary symptoms. Such symptoms may affect women's sexuality and quality of life, hence, there is a need for therapeutic options to ameliorate these symptoms [2]. (Source: Maturitas)
Source: Maturitas - April 24, 2024 Category: Primary Care Authors: Isadora B. Seganfredo, Cristina Bianchi, Maricy Tacla, Peter Chedraui, Jorge M. Haddad, Ricardo Simoes, Edmund C. Baracat, Jos é M. Soares Tags: Original article Source Type: research
EMAS position statement: Thyroid disease and menopause
Women experience menopause at a particular stage of their lifetime. On the other hand, subclinical hypothyroidism, mainly due to autoimmune thyroiditis, is a common endocrine disease in women during their reproductive years (the prevalence rate is 6 –10 %) [1] and is often present or arises during the menopausal transition. (Source: Maturitas)
Source: Maturitas - April 23, 2024 Category: Primary Care Authors: Gesthimani Mintziori, Stavroula Veneti, Kris Poppe, Dimitrios G. Goulis, Eleni Armeni, C. Tamer Erel, Ivan Fistoni ć, Timothy Hillard, Angelica Lindén Hirschberg, Blazej Meczekalski, Nicolás Mendoza, Alfred O. Mueck, Tommaso Simoncini, Petra Stute, Dor Tags: Original article Source Type: research
Pulse pressure is associated with decline in physical function in older adults
Frailty syndrome in older individuals is characterized by weight loss, weakness, slowness, low levels of physical activity, and exhaustion [1], and it is associated with disability [2] and mortality [3,4]. Handgrip strength and walking speed are frequently assessed to measure the physical function of older individuals, particularly those who have high blood pressure (BP) and are experiencing progressive vascular aging, which is a common chronic condition. [5]. Carotid-femoral or brachial-ankle pulse wave velocity is commonly used to evaluate arterial stiffness and vascular aging. (Source: Maturitas)
Source: Maturitas - April 22, 2024 Category: Primary Care Authors: Shao-Yuan Chuang, Wen-Ling Liu, Hao-Min Cheng, Ren-Hua Chung, Chia-Hung Lai, Shu-Chun Chuang, I-Chien Wu, Hsing-Yi Chang, Chao Agnes Hsiung, Wei J. Chen, Chih-Cheng Hsu Tags: Original article Source Type: research
When haemoglobin drops in the older hospitalized patient
Anaemia is a common comorbid condition in older patients admitted to hospitals. Currently, anaemia in older adults is attributed to three major causes: nutritional deficiencies, anaemia of inflammation (AI), and unexplained anaemia of ageing (UAA) [1]. (Source: Maturitas)
Source: Maturitas - April 20, 2024 Category: Primary Care Authors: Jenny Shun Wah Lee, Tung Wai Auyeung Tags: Editorial Source Type: research
The impact of a specialist-led digital health application on menopause symptoms in the workplace: A single-arm, longitudinal evaluation
Menopause is a natural process in normal female aging, resulting from depletion of ovarian follicles, and occurs at a median age of 51 years in Caucasian women and earlier in others, with the menopause transition usually starting at about 47 years. This period lasts until a year after menstruation has ceased and marks the menopause transition [1]. Although the transition happens to half the population, the experience varies co nsiderably from person to person [2]. While some women report no menopausal symptoms, others experience severe symptoms lasting for, at its worst, over a decade. (Source: Maturitas)
Source: Maturitas - April 20, 2024 Category: Primary Care Authors: Thea S. Schei, Kathy Abernethy Tags: Original Article Source Type: research
Hormone replacement therapy in women with iatrogenic premature ovarian insufficiency after radiotherapy for cervical cancer: A retrospective cohort and survey study
According to a GLOBOCAN summary of 185 countries in 2020, there were 604,127 cases of cervical cancer worldwide and 341,831 deaths. The majority of affected women are younger than 50 years of age at diagnosis [1]. As the average age of onset of natural menopause is 51 [2], most women diagnosed and treated for cervical cancer are premenopausal at the time of diagnosis. The treatment options for cervical cancer include surgery and/or (chemo)radiation therapy, depending on the s tage of the disease [3,4]. (Source: Maturitas)
Source: Maturitas - April 19, 2024 Category: Primary Care Authors: Charlotte van der Hoef, Lawrencia Dsane Bawuah, Nicoline Schuur, Yvonne V. Louwers, Jan Willem Mens, Nadia Hikary-Bhal, Helena C. van Doorn Tags: Original article Source Type: research
Longitudinal associations of polypharmacy and frailty with major cardiovascular events and mortality among more than half a million middle-aged participants of the UK Biobank
Polypharmacy, which is most commonly defined as concomitant use of 5 or more medications [1], is common in the older population due to increasing prevalence of multimorbidity with increasing age [2 –4]. Previous studies have shown significant associations of polypharmacy with falls, adverse drug reactions/events, hospitalization, and mortality [5]. As co-morbidity and age-related changes in medication pharmacokinetics and pharmacodynamics are more profound, polypharmacy is particularly probl ematic in frail patients [6]. (Source: Maturitas)
Source: Maturitas - April 19, 2024 Category: Primary Care Authors: Li-Ju Chen, Sha Sha, Hermann Brenner, Ben Sch öttker Tags: Original article Source Type: research
Healthy aging among centenarians and near-centenarians: Findings from the Georgia Centenarian Study
Living a long, satisfactory, and healthy life is a goal most, if not all, adults strive to attain. Demographic trends in all developed countries show that average life spans gradually get longer, and more adults live longer past the century mark [1]. As people live longer, more scientific studies are being conducted to unmask the underlying mechanisms that can contribute to living longer and well --- that is, healthy aging [2]. (Source: Maturitas)
Source: Maturitas - April 18, 2024 Category: Primary Care Authors: Peter Martin, Leonard W. Poon, for the Georgia Centenarian Study Tags: Review article Source Type: research
